Bibliography
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- •Short communication on the state of play in the field.
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- ••Excellent introduction to particleinteractions, although with little AFM content.
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- ••Excellent introduction to particleinteractions in inhalation, with good DPI content.
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- •Good general introduction to AFM.
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- •A colloid probe study of a lactose particle surface.
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- •First paper to use AFM single particle approach on an inhalation application.
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- •Shows increased cohesion force of salbutamol at high humidity.
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- •Study ranking the adhesion of a drug particle to various surfaces.
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- •Early paper with an attempt to quantify contact area.
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- •Good study of the effect of RH on drug cohesion, interesting observation about charge dissipation.
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- ••Calculation of particle W, by directimaging of asperities.
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- •Interesting comments on the use of contact mechanics in AFM experiments.
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- •Model to describe the effects of roughness of particle adhesion.
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- •Good review of DPI technology.
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- •Interesting novel comparative approach to particle adhesion, with comparison to other methods.
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- •Interesting novel cohesive-adhesive balance approach to particle adhesion.
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- •Good study of the effect of RH on drug carrier adhesion.
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- •Early paper showing variations in adhesion of a particle over a gelatin capsule.
- YOUNG PM, COCCONI D, COLOMBO P et al.: Characterisation of a surface modified dry powder inhalation carrier prepared by particle smoothing. Pharm. Pharmacol (2002) 54:1339–1344.
- •Experiment comparing adhesion of drug to different types of lactose, interesting correlation with impinger results.
- YOUNG PM, PRICE R, LEWIS D, EDGE S, TRAINI D: Under pressure: predicting pressurized metered dose inhaler interactions using the atomic force microscope. J. Colloid interface Sci. (2003) 262:298–302.
- •Experiment that ranks adhesion of salbutamol to various MDI materials.
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- •Study of adhesion to MDI container materials in model propellant.
- BEACH ER, TORMOEN GW, DRELICH J, HAN R: Pull-off force measurements between rough surfaces by atomic force microscopy. J. Colloid Interface Sci. (2002) 247:84–99.
- ••Detailed paper comparing experiment andmodelling of adhesion of rough surfaces.
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- •Determination of particle surface energy from AFM measurements, and attempts to allow for surface roughness.
- HOOTON JC, GERMAN CS, ALLEN S et al.: An AFM study of the effect of nanoscale contact geometry and surface chemistry on the adhesion of pharmaceutical particles. Pharm. Res. (2004) 21(6):952–960.
- •In depth study of RH effects on adhesion, proposes that asperity morphology determines behaviour.
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- •Good study of the effect of RH on drug-carrier adhesion.
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- RABINOVICH YT, ADLER JJ, ATA A, SINGH RK, MOUDGIL BM: Adhesion between nanoscale rough surfaces; II. measurement and comparison with theory. J. Colloid Interface Sci. (2000) 232:17–24.
- •Model to describe the effects of roughness on particle adhesion.
- NEWELL HE, BUCKTON G, BUTLER DA, THIELMANN F, WILLIAMS DR: The use of inverse gas chromatography to measure the surface energy of crystalline, amorphous and recently milled lactose. Pharm. Res. (2001) 18(5):662–666.
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- VETTIGER P, DESPONT M, DRECHSLER U et al.: The "Millipede" - more than one thousand tips for future AFM data storage. IBM J. Res. Dev. (2000) 44(3):323–340.
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- JONES R, POLLOCK HM, GELDART D, VERLINDEN-LUTS A: Frictional forces between cohesive powder particles studied by AFM. Ultramicroscopy (2004) 100(1-2):59–78.
- •Interesting paper using AFM to measure and quantify particle friction.
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