Potentials and challenges in self-nanoemulsifying drug delivery systems

Bibliography

• Stegemann S, Leveiller F, Franchi D, When poor solubility becomes an issue: from early stage to proof of concept. Eur J Pharm Sci 2007;31:249-61
   PubMed Web of Science ®Google Scholar
• Liversidge EM. Nanocrystals: resolving pharmaceutical formulation issues associated with poorly water-soluble compounds, paper 45. Particles; Orlando, Florida: 2002. p. 20-3
   Google Scholar
• York P. The design of dosage forms. In: Aulton ME, editor. Pharmaceutics the science of dosage form design. Churchill Livingstone; Edinburgh: 1988. p. 1-13
   Google Scholar
• Cavallari C, Abertini B, Gonzalez-Rodriguez ML, Rodriguez L. Improved dissolution behaviour of steam-granulated piroxicam. Eur J Phar Biopharm 2002;54:65-73
   PubMed Web of Science ®Google Scholar
• Serajuddin ATM. Solid dispersion of poorly water soluble drugs: early promises, subsequent problems and recent breakthroughs. J Pharm Sci 1999;88:1058-66
   PubMed Web of Science ®Google Scholar
• Aungst BJ. Novel formulation strategies for improving oral bioavailability of drugs with poor membrane permeation or presystemic metabolism. J Pharm Sci 1993;82:979-86
   PubMed Web of Science ®Google Scholar
• Paradkar A, Ambike AA, Jadhav BK, Mahadik KR. Characterization of curcumin-PVP solid dispersion obtained by spray drying. Int J Pharm 2004;271:281-6
   PubMed Web of Science ®Google Scholar
• Aungst BJ, Nguyen N, Rogers NJ, Improved oral bioavailability of an HIV protease inhibitor using Gelucire 44/14 and Labrasol vehicles. B T Gattefosse 1994;87:49-54
   Google Scholar
• Kotta S, Khan AW, Pramod K, Exploring oral nanoemulsions for bioavailability enhancement of poorly water-soluble drugs. Expert Opin Drug Deliv 2012;9(5):585-98
   PubMed Web of Science ®Google Scholar
• Singh B, Bandopadhyay S, Kapil R, Self-emulsifying drug delivery systems (SEDDS): formulation development, characterization, and applications. Crit Rev Ther Drug Carrier Syst 2009;26:427-521
   PubMed Web of Science ®Google Scholar
• Patel PA, Chaulang GM, Akolkotkar A, Self emulsifying drug delivery system: a review. Res J Pharm Tech 2008;1(4):313-23
   Google Scholar
• Pouton CW. Lipid formulations for oral administration of drugs: non-emulsifying, self-emulsifying and ‘self-microemulsifying' drug delivery systems. Eur J Pharm Sci 2000;11(Suppl 2):S93-8
   PubMed Web of Science ®Google Scholar
• Pouton CW, Porter CJ. Formulation of lipid-based delivery systems for oral administration: materials, methods and strategies. Adv Drug Deliv Rev 2008;60:625-37
   PubMed Web of Science ®Google Scholar
• Graves S, Meleson K, Wilking J, Structure of concentrated nanoemulsions. J. Chem. Phys 2005;122:134703-6
   PubMed Web of Science ®Google Scholar
• Mahmoud EA, Bendas ER, Mohamed MI. Preparation and evaluation of self-nanoemulsifying tablets of carvedilol. AAPS PharmSciTech 2009;10(1):183-92
   PubMed Web of Science ®Google Scholar
• Gao P, Morozowich W. Development of supersaturatable selfemulsifying drug delivery system formulations for improving the oral absorption of poorly soluble drugs. Expert Opin Drug Discov 2006;3:97-110
   Google Scholar
• Nazzal S, Khan MA. Controlled release of a self-emulsifying formulation formulation from a tablet dosage form: stability assessment and optimization of some processing parameters. Int J Pharm 2006;315:110-21
   PubMed Web of Science ®Google Scholar
• Gao P, Rush BD, Pfund WP. Development of a supersaturable SEDDS (S-SEDDS) formulation of paclitaxel with improved oral bioavailability. J Pharm Sci 2003;92:2386-98
   PubMed Web of Science ®Google Scholar
• Thomas N, Müllertz A, Graf A, Rades T. Influence of lipid composition and drug load on the in vitro performance of self-nanoemulsifying drug delivery systems. J Pharm Sci 2012;101:1721-31
   PubMed Web of Science ®Google Scholar
• Nielsen FS, Petersen KB, Müllertz A. Bioavailability of probucol from lipid and surfactant based formulations in minipigs: influence of droplet size and dietary state. Eur J Pharm Biopharm 2008;69(2):553-62
   PubMed Web of Science ®Google Scholar
• Grove M, Müllertz A, Pedersen GP, Nielsen JL. Bioavailability of seocalcitol III. Administration of lipid-based formulations to minipigs in the fasted and fed state. Eur J Pharm Sci 2007;31(1):8-15
   PubMed Web of Science ®Google Scholar
• Woo JS, Song YK, Hong JY, Reduced food-effect and enhanced bioavailability of a self-microemulsifying formulation of itraconazole in healthy volunteers. Eur J Pharm Sci 2008;33(2):159-65
   PubMed Web of Science ®Google Scholar
• Taha E, Ghorab D, Zaghloul AA. Bioavailability assessment of vitamin a self-nanoemulsified drug delivery systems in rats. A Comp Study Med Princ Pract 2007;16:355-9
   PubMed Web of Science ®Google Scholar
• Silva BFB, Marques EF, Olsson U, Size, Shape, and charge of salt-free catanionic microemulsion droplets: a small-angle neutron scattering and modeling study. J Phys Chem B 2009;113:10230-9
   PubMed Web of Science ®Google Scholar
• Charman WN, Noguchi T, Stella VJ. An experimental system designed to study the in situ intestinal lymphatic transport of lipophilic drugs in anesthetized rats. Int J Pharm 1986;33:155-64
   Web of Science ®Google Scholar
• Myers RA, Stella VJ. Factors affecting the lymphatic transport of penclomedine (NSC-338720), a lipophilic cytotoxic drug: comparison to DDT and hexachlorobenzene. Int J Pharm 1992;80:511-162
   Web of Science ®Google Scholar
• Zhao Y, Wang C, Chow AHL, Self-nanoemulsifying drug delivery system (SNEDDS) for oral delivery of Zedoary essential oil: formulation and bioavailability studies. Int J Pharm 2010;383:170-7
   PubMed Web of Science ®Google Scholar
• Odeberga JM, Kaufmannb P, Kroonc KG, Höglunda P. Lipid drug delivery and rational formulation design for lipophilic drugs with low oral bioavailability, applied to cyclosporine. Eur J Pharm Sci 2003;20:375-82
   PubMed Web of Science ®Google Scholar
• Kimura M, Shizuki M, Miyoshi K, Relationship between the molecular structures and emulsification properties of edible oils. Biosci Biotech Biochem 1994;58:1258-61
   PubMed Web of Science ®Google Scholar
• Hauss DJ, Fogal SE, Ficorilli JV, Lipid-based delivery systems for improving the bioavailability and lymphatic transport of a poorly water-soluble LTB4 inhibitor. J Pharm Sci 1998;87:164-9
   PubMed Web of Science ®Google Scholar
• Kassem AA, Marzouk MA, Ammar AA, Elosaily GH. Preparation and in vitro evaluation of self-nanoemulsifying drug delivery systems (SNEDDS) containing clotrimazole. Drug Discov Ther 2010;4(5):373-9
   PubMedGoogle Scholar
• Basalious EB, Shawky N, Badr-Eldin SM. SNEDDS containing bioenhancers for improvement of dissolution and oral absorption of lacidipine. I: development and optimization. Int J Pharm 2010;391:203-11
   PubMed Web of Science ®Google Scholar
• Prajapati HN, Dalrymple DM, Serajudin ATM. A comparative evaluation of mono-, di- and triglyceride of medium chain fatty acids by lipid/surfactant/water phase diagram, solubility determination and dispersion testing for application in pharmaceutical dosage form development. Pharm Res 2012;29:285-305
   PubMed Web of Science ®Google Scholar
• Parmar N, Singla N, Amina S, Kohli K. Study of cosurfactant effect on nanoemulsifying area and development of lercanidipine loaded (SNEDDS) self nanoemulsifying drug delivery system. Colloids Surf B Biointerfaces 2011;86(2):327-38
   PubMed Web of Science ®Google Scholar
• Rowe RC, Sheskey PJ, Weller PJ. Pharmaceutical excipients handbook. Pharmaceutical Press and American Pharmaceutical Association; Dundee: 2003
   Google Scholar
• Torchlin VP. Nanoparticulates as drug carriers. ICP; London: 2006
   Google Scholar
• Lawrence MJ, Rees GD. Microemulsion based media as novel drug delivery systems. Adv Drug Deliv 2000;45:89-121
   PubMed Web of Science ®Google Scholar
• Poelma FG, Breäs R, Tukker JJ. Intestinal absorption of drugs. III. The influence of taurocholate on the disappearance kinetics of hydrophilic and lipophilic drugs from the small intestine of the rat. Pharm Res 1990;7:392-7
   PubMed Web of Science ®Google Scholar
• Chiu YY, Higaki K, Neudeck BL, Human jejunal permeability of cyclosporin A: influence of surfactants on P-glycoprotein efflux in Caco-2 cells. Pharm Res 2003;20:749-56
   PubMed Web of Science ®Google Scholar
• Anton N, Vandamme TF. Nano-emulsions and Micro-emulsions: clarifications of the Critical Differences. Pharm Res 2011;28:978-85
   PubMed Web of Science ®Google Scholar
• Meinzer A, Mueller E, Vondersher J. Microemulsion: a suitable galenical approach for the absorption enhancement of low soluble compounds? B T Gattefosse 1995;88:21-6
   Google Scholar
• Vonderscher J. Meinzer, A. Rationale for the development of Sandimmune Neoral. Transplant Proc 1994;26:2925-2927A
   PubMed Web of Science ®Google Scholar
• Ghosh PK, Majithiya RJ, Umertiia ML, Murthy RS. Design and development of microemulsion drug delivery system of acyclovir for improvement of oral bioavailability. APPS PharmSciTech 2006;7:77
   PubMed Web of Science ®Google Scholar
• Ghosh PK, Murthy RS. Microemulsion a potential drug delivery system. Curr Drug Deliv 2006;3:167-80
   PubMedGoogle Scholar
• Garti N, Yaghmur A, Leser ME, Improved oil solubilization in oil/water food grade microemulsions in the presence of polyols and ethanol. J Agric Food Chem 2001;49:2552-62
   PubMed Web of Science ®Google Scholar
• Eccleston J. Microemulsions. In: Swarbrick J, Boylan JC, editors. Encyclopedia of pharmaceutical technology. Marcel Dekker; New York: 1994. p. 375-421
   Google Scholar
• Reiss H. Entropy induced dispersion of bulk liquids. J Colloids Interface Sci 1975;53:61-70
   Web of Science ®Google Scholar
• Groves MJ, Galindez DAD. The self-emulsifying action of mixed surfactants in oil. Acta Pharma Suecica 1976;13:361-72
   PubMedGoogle Scholar
• Wakerly MG, Pouton CW, Meakin BJ, Morton FS. Self-emulsification of vegetable oil-nonionic surfactant mixture: a proposed mechanism of action. ACS Symp. Ser 1986;311:242-55
   Google Scholar
• Craig DQM, Lievens HSR, Pitt KG, Storey DE. An investigation into the physicochemical properties of self-emulsifying systems using low frequency dielectric spectroscopy, surface tension measurements and particle size analysis. Int J Pharm 1993;96:147-55
   Web of Science ®Google Scholar
• Craig DQM. The use of self-emulsifying systems as a means of improving drug delivery. B.T. Gattefosse 1993;86:21-31
   Google Scholar
• Craig DQM, Barker SA, Banning D, Booth SW. An investigation into the mechanisms of self-emulsification using particle size analysis and low frequency dielectric spectroscopy. Int J Pharm 1995;114:103-10
   Web of Science ®Google Scholar
• Forgiarini A, Esqucna J, Gonza´lez C, Solans C. Formation of nano-emulsions by low-energy emulsification methods at constant temperature. Langmuir 2001;17:2076-83
   Web of Science ®Google Scholar
• Forgiarini A, Esqucna J, Gonzalez C, Solans C. Studies of the relation between phase behavior and emulsification methods with nanoemulsion formation. Prog Colloid Polym Sci 2000;115:36-9
   Google Scholar
• Sole I, Solans C, Maestro A, Study of nano-emulsion formation by dilution of microemulsions. J Colloid Interface Sci 2012;376:133-9
   PubMed Web of Science ®Google Scholar
• Pouton CW. Formulation of self-emulsifying drug delivery systems. Adv Drug Deliv Rev 1997;25:47-58
   Web of Science ®Google Scholar
• Goddeeris C, Cuppob F, Reynaersb H, Light scattering measurements on microemulsions: estimation of droplet sizes. Int J Pharm 2006;312:187-95
   PubMed Web of Science ®Google Scholar
• Yang S, Gursoy RN, Lambert G, Benita S. Enhanced oral absorption of paclitaxel in a novel self-microemulsifying drug delivery system with or without concomitant use of P-glycoprotein inhibitors. Pharm Res 2004;21:261-70
   PubMed Web of Science ®Google Scholar
• Wang L, Dong J, Chen J, Design and optimization of a new self-nanoemulsifying drug delivery system. J Colloids Interface Sci 2009;330:0443-8
   PubMed Web of Science ®Google Scholar
• Gursoy N, Garrigue JS, Razafindratsita A, Excipient effects on in vitro cytotoxicity of a novel paclitaxel self-emulsifying drug delivery system. J Pharm Sci 2003;92:2411-18
   PubMed Web of Science ®Google Scholar
• Nazzal S, Smalyukh II, Lavrentovich OD, Khan MA. Preparation and in vitro characterization of a eutectic based semisolid self-nanoemulsified drug delivery system (SNEDDS) of ubiquinone: mechanism and progress of emulsion formation. Int J Pharm 2002;235:247-65
   PubMed Web of Science ®Google Scholar
• Palamakula A, Khan MA. Evaluation of cytotoxicity of oils used in coenzyme Q10 self-emulsifying drug delivery systems (SEDDS). Int J Pharm 2004;273:63-73
   PubMed Web of Science ®Google Scholar
• Subramanian N, Ray S, Ghosal SK, Formulation design of self-microemulsifying drug delivery systems for improved oral bioavailability of celecoxib. Biol Pharm Bull 2004;27:1993-9
   PubMed Web of Science ®Google Scholar
• Gershanik T, Benita S. Positively charged self-emulsifying oil formulation for improving the oral bioavailability of progestrone. Pharm Dev Technol 1996;1:147-57
   PubMedGoogle Scholar
• Shahnaz G, Hartl M, Barthelmes J, Uptake of phenothiazines by the harvested chylomicrons ex vivo model: Influence of self-nanoemulsifying formulation design. Eur J Pharm Biopharm 2011;79(1):171-80
   PubMed Web of Science ®Google Scholar
• Yoo JH, Shanmugam S, Thapa P, Novel self-nanoemulsifying drug delivery system for enhanced solubility and dissolution of lutein. Arch Pharm Res 2010;33:417-26
   PubMed Web of Science ®Google Scholar
• Wankhade V, Tapar K, Pande S, Bobade N. Design and evaluation of self-nanoemulsifying drug delivery systems (SNEDDS) for Gliclazide. Der Pharmacia Lett 2010;2:132-43
   Google Scholar
• Patil P, Joshi P, Paradkar A. Effect of formulation variables on preparation and evaluation of gelled self-emulsifying drug delivery system (SEDDS) of Ketoprofen. AAPS PharmSciTech 2004;5:E42
   PubMedGoogle Scholar
• El-Laithy HM. Self-nanoemulsifying drug delivery system for enhanced bioavailability and improved hepatoprotective activity of Biphenyl Dimethyl Dicarboxylate. Curr Drug Deliv 2008;5:170-6
   PubMedGoogle Scholar
• Zhao Y, Wang C, Chow AH, Self-nanoemulsifying drug delivery system (SNEDDS) for oral delivery of zedoary essential oil: formulation and bioavailability studies. Int J Pharm 2010;383:170-7
   PubMed Web of Science ®Google Scholar
• Khoo S-M, Porter CJH, Charman WN. The formulation of halofantrine as either non-solubilising PEG 6000 or solubilising lipid based solid dispersions: physical, stability and absolute bioavailability assessment. Int J Pharm 2000;205:65-78
   PubMed Web of Science ®Google Scholar
• Nazzal S, Guven N, Reddy IK, Khan MA. Preparation and characterization of coenzyme QlO-Eudragit solid dispersion. Drug Dev Ind Pharm 2002;28:49-57
   PubMed Web of Science ®Google Scholar
• Nyqvist-Mayer AA, Brodin AF, Frank SG. Phase distribution studies on an oil-water emulsion based on a eutectic mixture of lidocaine and prilocaine as the dispersed phase. Pharm Sci 1985;74:1192-5
   PubMed Web of Science ®Google Scholar
• Kang LS, Jun HW, McCall JW. Physicochemical studies of lidocaine-menthol binary systems for enhanced membrane transport. Int J Pharm 2000;206:35-42
   PubMed Web of Science ®Google Scholar
• Date AS, Nagarsenker MS. Design and evaluation of self-nanoemulsifying drug delivery systems (SNEDDS) for cefpodoxime proxetil. Int J Pharm 2007;329:166-72
   PubMed Web of Science ®Google Scholar
• Humberstone AJ, Charman WN. Lipid based vehicles for oral delivery of poorly water soluble drugs. Adv Drug Deliv Rev 1997;25:103-28
   Web of Science ®Google Scholar
• Patel D, Sawant KK. Oral bioavailability enhancement of acyclovir by self-microemulsifying drug delivery systems (SMEDDS). Drug Dev. Ind Pharm 2007;33:1318-26
   Google Scholar
• Porter CJ, Trevaskis NL, Charman WN. Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs. Nat Rev Drug Discov 2007;6:231-48
   PubMed Web of Science ®Google Scholar
• Oh DH, Kang JH, Kim DW, Comparison of solid self-microemulsifying drug delivery system (solid SMEDDS) prepared with hydrophilic and hydrophobic solid carrier. Int J Pharm 2011;420:412-18
   PubMed Web of Science ®Google Scholar