Advantages and risks of nanotechnologies in cancer patients and occupationally exposed workers

Bibliography

• Boyle P, Levin B. editors. Worldwide cancer burden. In: World cancer report 2014. International Agency for Research on Cancer; Lyon, France: 2014. p. 16-54
   Google Scholar
• Cheong I, Huang X, Thornton K, et al. Targeting cancer with bugs and liposomes: ready, aim, fire. Cancer Res 2007;67:9605-8
   PubMed Web of Science ®Google Scholar
• Caraglia M, Marra M, Misso G, et al. Tumour-specific uptake of anti-cancer drugs: the future is here. Curr Drug Metab 2012;13:4-21
   PubMed Web of Science ®Google Scholar
• Roger E, Lagarce F, Garcion E, Benoit J-P. Biopharmaceutical parameters to consider in order to alter the fate of nanocarriers after oral delivery. Nanomedicine 2010;5(2):287-306
   PubMed Web of Science ®Google Scholar
• Sharma A, Madhunapantula SV, Robertson GP. Toxicological considerations when creating nanoparticle-based drugs and. Expert Opin Drug Metab Toxicol 2012;8:47-69
   PubMed Web of Science ®Google Scholar
• Savolainen K, Alenius H, Norppa H, et al. Risk assessment of engineered nanomaterials and nanotechnologies--a review. Toxicology 2010;269:92-104
   PubMed Web of Science ®Google Scholar
• Schulte PA, Trout D, Zumwalde RD, et al. Options for occupational health surveillance of workers potentially exposed to engineered nanoparticles: state of the science. J Occup Environ Med 2008;50:517-26
   PubMed Web of Science ®Google Scholar
• Couvreur P, Kante B, Roland M, Speiser P. Adsorption of antineoplastic drugs to polyalkylcyanoacrylate nanoparticles and their release in calf serum. J Pharm Sci 1979;68:1521-4
   PubMed Web of Science ®Google Scholar
• Gullotti E, Yeo Y. Extracellularly activated nanocarriers: a new paradigm of tumor targeted drug delivery. Mol Pharm 2009;6:1041-51
   PubMed Web of Science ®Google Scholar
• Li SD, Huang L. Pharmacokinetics and biodistribution of nanoparticles. Mol Pharm 2008;5:496-504
   PubMed Web of Science ®Google Scholar
• Alexis F, Pridgen E, Molnar LK, Farokhzad OC. Factors affecting the clearance and biodistribution of polymeric nano-particles. Mol Pharm 2008;5:505-15
   PubMed Web of Science ®Google Scholar
• Levy I, Roberts J, Baum M. The use of liposomes in the diagnosis and treatment of malignant disease. Postgrad Med J 1987;63:829-33
   PubMed Web of Science ®Google Scholar
• Drummond DC, Meyer O, Hong K, et al. Optimizing liposomes for delivery of chemotherapeutic agents to solid tumors. Pharmacol Rev 1999;51:691-743
   PubMed Web of Science ®Google Scholar
• Weissig V, Torchilin VP. Liposomes: a practical approach. In: Torchilin VP, Weissig V, editors. Surface modifications of liposomes. Oxford University Press, Oxford; 2003. p. 384
   Google Scholar
• Maeda H. Enhanced permeability and retention (EPR) effect: basis for drug targeting to tumors. In: Muzykantov V, Torchilin VP, editors. Biomedical aspects of drug targeting. Kluwer, Boston, MA; 2003. p. 211-28
   Google Scholar
• Storm G, Oussoren C, Peeters PAM, Barenholz Y. Tolerability of liposomes in vivo. In: Gregoriadis G, editor. Liposome technology. CRC Press, Inc, Boca Raton, FL; 1993. p. 345-383
   Google Scholar
• Shmeeda H, Amitay Y, Gorin J, et al. Delivery of zoledronic acid encapsulated in folate-targeted liposome results in potent in vitro cytotoxic activity on tumor cells. J Control Release 2010;146(1):76-83
   PubMed Web of Science ®Google Scholar
• Shmeeda H, Amitay Y, Tzemach D, et al. Liposome encapsulation of zoledronic acid results in major changes in tissue distribution and increase in toxicity. J Control Release 2013;167(3):265-75
   PubMed Web of Science ®Google Scholar
• Marra M, Salzano G, Leonetti C, et al. Nanotechnologies to use bisphosphonates as potent anticancer agents: the effects of zoledronic acid encapsulated into liposomes. Nanomedicine 2011;7(6):955-64
   PubMed Web of Science ®Google Scholar
• Elbayoumi TA, Torchilin VP. “Tumor-specific antmediated targeted delivery of Doxil reduces the manifestof auricular erythema side effect in mice”. Int J Pharm 2008;357(1-2):272-9
   PubMed Web of Science ®Google Scholar
• Sahoo NG, Bao H, Pan Y, et al. Functionalized carbon nanomaterials as nanocarriers for loading and delivery of a poorly water-soluble anticancer drug: a comparative study. Chem Commun 2011;47:5235-7
   PubMed Web of Science ®Google Scholar
• Kang B, Chang S, Dai Y, et al. Cell response to carbon nanotubes: size-dependent intracellular uptake mechanism and subcellular fate. Small 2010;6(21):2362-6
   PubMed Web of Science ®Google Scholar
• Mallick K, Strydom AM. Biophilic carbon nanotubes. Colloids Surf B Biointerfaces 2013;105:310-18
   PubMed Web of Science ®Google Scholar
• Bianco A, Kostarelos K, Prato M. Applications of carbon nanotubes in drug delivery. Curr Opin Chem Biol 2005;9:674-9
   PubMed Web of Science ®Google Scholar
• Lim DJ, Sim M, Oh L, et al. Carbon-based drug delivery carriers for cancer therapy. Arch Pharm Res 2014;37(1):43-52
   PubMed Web of Science ®Google Scholar
• Chen H, Ma X, Li Z, et al. Functionalization of single-walled carbon nanotubes enables efficient intracellular delivery of siRNA targeting MDM2 to inhibit breast cancer cells growth. Biomed Pharmacother 2012;60(5):334-8
   Web of Science ®Google Scholar
• Avti PK, Sitharaman B. Luminescent single-walled carbon nanotube-sensitized europium nanoprobes for cellular imaging. Int J Nanomedicine 2012;7:1953-64
   PubMed Web of Science ®Google Scholar
• Magrini A, Bergamaschi A, Bergamaschi E. Carbon nanotubes (CNT) and nanoparticles (NP): interaction with lung epithelium and other biological systems. G Ital Med Lav Ergon 2006;28(3):266-9
   PubMedGoogle Scholar
• Johnston HJ, Hutchison GR, Christensen FM, et al. A critical review of the biological mechanisms underlying the in vivo and in vitro toxicity of carbon nanotubes: the contribution of physico-chemical characteristics. Nanotoxicology 2010;4(2):207-46
   PubMed Web of Science ®Google Scholar
• Haag R. Supramolecular drug-delivery systems based on polymeric core–shell architectures. Angew Chem Int Ed 2004;43:278-82
   PubMed Web of Science ®Google Scholar
• Adams ML, Lavasanifar A, Kwon GS. Amphiphilic block copolymers for drug delivery. J Pharm Sci 2003;92(7):1343-55
   PubMed Web of Science ®Google Scholar
• Ostacolo L, Marra M, Ungaro F, et al. In vitro anticancer activity of docetaxel-loaded micelles based on poly(ethylene oxide)-poly(epsilon-caprolactone) block copolymers: do nanocarrier properties have a role? J Control Release 2010;148(2):255-63
   PubMed Web of Science ®Google Scholar
• Ungaro F, Conte C, Ostacolo L, et al. Core-shell biodegradable nanoassemblies for the passive targeting of docetaxel: features, antiproliferative activity and in vivo toxicity. Nanomedicine 2012;8(5):637-46
   PubMed Web of Science ®Google Scholar
• Duncan R, Gac-Breton S, Keane R, et al. Polymer-drug conjugates, PDEPT and PELT: basic principles for design and transfer from the laboratory to clinic. J Control Release 2001;74(1-3):135-46
   PubMed Web of Science ®Google Scholar
• Xue Y, Tang X, Huang J, et al. Anti-tumor efficacy of polymer-platinum(II) complex micelles fabricated from folate conjugated PEG-graft-α,β-poly [(N-amino acidyl)-aspartamide] and cis-dichlorodiammine platinum(II) in tumor-bearing mice. Colloids Surf B Biointerfaces 2011;85(2):280-8
   PubMed Web of Science ®Google Scholar
• Chung YI, Kim JC, Kim YH, et al. The effect of surface functionalization of PLGA nanoparticles by heparin- or chitosan-conjugated Pluronic on tumor targeting. J Control Release 2010;143(3):374-82
   PubMed Web of Science ®Google Scholar
• Weissleder R, Tung CH, Mahmood U, et al. In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nat Biotechnol 1999;17(4):375-8
   PubMed Web of Science ®Google Scholar
• Kim SE, Kwon IC, Song HR, et al. Insight of key factors influencing tumor targeting characteristics of Glycol Chitosan-based nanoparticles and in vivo applications. Macromol Res 2012;20(11):1109-17
   Web of Science ®Google Scholar
• Lee CC, MacKay JA, Fréchet JM, Szoka FC. Designing dendrimers for biological applications. Nat Biotechnol 2005;23(12):1517-26
   PubMed Web of Science ®Google Scholar
• Tomalia DA, Baker H, Dewald J, et al. Dendritic macromolecules: synthesis of starburst dendrimers. Macromolecules 1986;19(9):2466-8
   Web of Science ®Google Scholar
• Hawkerand J, Frechet MJ. Preparation of polymers with controlled molecular architecture. A new convergent approach to dendritic macromolecules. J Am Chem Soc 1990;112(21):7638-47
   Web of Science ®Google Scholar
• Wang P, Zhao XH, Wang ZY, et al. Generation 4 polyamidoamine dendrimers is a novel candidate of nano-carrier for gene delivery agents in breast cancer treatment. Cancer Lett 2010;298(1):34-49
   PubMed Web of Science ®Google Scholar
• Gupta U, Dwivedi SKD, Bid HK, et al. Ligand anchored dendrimers based nanoconstructs for effective targeting to cancer cells. Int J Pharm 2010;393(2):186-97
   Web of Science ®Google Scholar
• Samuelson LE, Dukes MJ, Hunt CR, et al. TSPO targeted dendrimer imaging agent: synthesis, characterization, and cellular internalization. Bioconjug Chem 2009;20:2082-9
   PubMed Web of Science ®Google Scholar
• Solans C, Izquierdo P, Nolla J, et al. Nano-emulsions. Curr Opin Colloid Interface Sci 2005;10:102
   Web of Science ®Google Scholar
• Ganta S, Paxton JW, Baguley BC, Garg S. Pharmacokinetics and pharmacodynamics of chlorambucil delivered in parenteral emulsion. Int J Pharm 2008;360(1-2):115-21
   PubMed Web of Science ®Google Scholar
• Khanal A, Inoue Y, Yada M, et al. Synthesis of silica hollow nanoparticles templated by polymeric micelle with core-shell-corona structure. J Am Chem Soc 2007;129:1534-5
   PubMed Web of Science ®Google Scholar
• Yang J, Lee J, Kang J, et al. Hollow silica nanocontainers as drug delivery vehicles. Langmuir 2008;24:3417-21
   PubMed Web of Science ®Google Scholar
• Venkatesan P, Puvvada N, Dash R, et al. The potential of celecoxib-loaded hydroxyapatite-chitosan nanocomposite for the treatment of colon cancer. Biomaterials 2011;32(15):3794-806
   PubMed Web of Science ®Google Scholar
• Wang KW, Zhu YJ, Chen XY, et al. Flower-like hierarchically nanostructured hydroxyapatite hollow spheres: facile preparation and application in anticancer drug cellular delivery. Chem Asian J 2010;5(12):2477-82
   PubMed Web of Science ®Google Scholar
• Morales MP, Bomati-Miguel O, de Alejo RP, et al. Contrast agents for MRI based on iron oxide nanoparticles prepared by laser pyrolysis. J Magn Magn Mater 2003;266:102-9
   Web of Science ®Google Scholar
• Mahfouz AE, Hamm B, Taupitz M. Contrast agents for MR imaging of the liver: a clinical overview. Eur Radiol 1997;7:507-13
   PubMed Web of Science ®Google Scholar
• Martinez-Mera I, Espinosa ME, Perez-Hernandez R, et al. Synthesis of magnetite (Fe“3O”4) nanoparticles without surfactants at room temperature. J Mater Lett 2007;61:4447
   Web of Science ®Google Scholar
• Chastellain M, Petri A, Gupta A, et al. Scalable synthesis of new class of polymer microrods by a liquid-liquid dispersion technique. Adv Eng MaterAdv Eng Mater 2004;6:235
   Web of Science ®Google Scholar
• Sun C, Veiseh O, Gunn J, et al. In vivo MRI detection of gliomas by chlorotoxin-conjugated superparamagnetic nanoprobes. Small 2008;4:372-9
   PubMed Web of Science ®Google Scholar
• Apopa PL, Qian Y, Shao R, et al. Iron oxide nanoparticles induce human microvascular endothelial cell permeability through reactive oxygen species production and microtubule remodeling. Part Fibre Toxicol 2009;6:1
   PubMed Web of Science ®Google Scholar
• Zhang H, Chen B, Jiang H, et al. A strategy for ZnO nanorod mediated multi-mode cancer treatment. Biomaterials 2011;32(7):1906-14
   PubMed Web of Science ®Google Scholar
• Duncan B, Kim C, Rotello VM. Gold nanoparticle platforms as drug and biomacromolecule delivery systems. J Control Release 2010;148:122-7
   PubMed Web of Science ®Google Scholar
• Giljohann DA, Seferos DS, Prigodich AE, et al. Gene regulationwith polyvalent siRNA-nanoparticle conjugates. J Am Chem Soc 2009;131:2072-3
   PubMed Web of Science ®Google Scholar
• Kim CK, Ghosh P, Pagliuca C, et al. Entrapment of hydrophobic drugs in nanoparticle monolayers with efficient release into cancer cells. J Am Chem Soc 2009;131:1360-1
   PubMed Web of Science ®Google Scholar
• Albanese A, Chan WCW. Effect of gold nanoparticle aggregation on cell uptake and toxicity. ACS Nano 2011;5(7):5478-89
   PubMed Web of Science ®Google Scholar
• Eghtedari M, Liopo AV, Copland JA, et al. Engineering of hetero-functional gold nanorods for the in vivo molecular targeting of breast cancer cells. Nano Lett 2009;9(1):287-91
   PubMed Web of Science ®Google Scholar
• Connor EE, Mwamuka J, Gole A, et al. Gold nanoparticles are taken up by human cells but do not cause acute cytotoxicity. Small 2005;1(3):325-7
   PubMed Web of Science ®Google Scholar
• Xiao Y, Hong H, Matson VZ, et al. Gold nanorods conjugated with Doxorubicin and cRGD for combined anticancer drug delivery and Pet imaging. Thernostics 2012;2(8):757-68
   PubMed Web of Science ®Google Scholar
• Wang C, Chen J, Talavage T, et al. Gold Nanorod/Fe3O4 nanoparticle “nano-pearl-necklaces” for simultaneous targeting, dual-mode imaging, and photothermal ablation of cancer cells. Angew Chem 2009;48(15):2759-276
   Web of Science ®Google Scholar
• Ferreira AJ, Cemlyn-Jones J, Robalo Cordeiro C. Nanoparticles, nanotechnology and pulmonary nanotoxicology. Rev Port Pneumol 2013;19(1):28-37
   PubMed Web of Science ®Google Scholar
• Zarogoulidis P, Giraleli C, Karamanos NK. Inhaled chemotherapy in lung cancer: safety concerns of nanocomplexes delivered. Ther Deliv 2012;3(9):1021-3
   PubMedGoogle Scholar
• Kendall M, Holgate S. Health impact and toxicological effects of nanomaterials in the lung. Respirology 2012;17(5):743-58
   PubMed Web of Science ®Google Scholar
• Morimoto Y, Hirohashi M, Ogami A, et al. Pulmonary toxicity of well-dispersed multi-wall carbon nanotubes following inhalation and intratracheal instillation. Nanotoxicology 2012;6(6):587-99
   PubMed Web of Science ®Google Scholar
• Wang L, Stueckle TA, Mishra A, et al. Neoplastic-like transformation effect of single-walled and multi-walled carbon nanotubes compared to asbestos on human lung small airway epithelial cells. Nanotoxicology 2014;8(5):485-507
   PubMed Web of Science ®Google Scholar
• Sargent LM, Porter DW, Staska LM, et al. Promotion of lung adenocarcinoma following inhalation exposure to multi-walled carbon nanotubes. Part Fibre Toxicol 2014;11(1):3
   PubMed Web of Science ®Google Scholar
• Nemmar A, Hoet PH, Vanquickenborne B, et al. Passage of inhaled particles into the blood circulation in humans. Circulation 2002;105(4):411-14
   PubMed Web of Science ®Google Scholar
• Dokka S, Toledo D, Shi X, et al. Oxygen radical-mediated pulmonary toxicity induced by some cationic liposomes. Pharm Res 2000;17:521-5
   PubMed Web of Science ®Google Scholar
• Khandoga A, Stampfl A, Takenaka S, et al. Ultrafine particles exert prothrombotic but not inflammatory effects on the hepatic microcirculation in healthy mice in vivo. Circulation 2004;109(10):1320-5
   PubMed Web of Science ®Google Scholar
• Radomski A, Jurasz P, Alonso-Escolano D, et al. Nanoparticle-induced platelet aggregation and vascular thrombosis. Br J Pharmacol 2005;146(6):882-93
   PubMed Web of Science ®Google Scholar
• Hoet PH, Bruske-Hohlfeld I & Salata OV. Nanoparticles—known and unknown health risks. J Nanobiotechnol 2004;2:12
   PubMedGoogle Scholar
• Oberdorster E. Manufactured nanomaterials (fullerenes, C60) induce oxidative stress in the brain of juvenile largemouth bass. Environ Health Perspect 2004;112:1058-62
   PubMed Web of Science ®Google Scholar
• Panyala N, Pena-Mendez EM, Havel J. Silver or silver nanoparticles: a hazardous threat to the environment and human health? J Appl Biomed 2008;6:17-129
   Google Scholar
• Sarin H, Kanevsky AS, Wu H, et al. Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells. J Transl Med 2008;6:80
   PubMed Web of Science ®Google Scholar
• Caraglia M, Luongo L, Salzano G, et al. Stealth liposomes encapsulating zoledronic acid: a new opportunity to treat neuropathic pain. Mol Pharm 2013;10(3):1111-18
   PubMed Web of Science ®Google Scholar
• Tang J, Xiong L, Wang S, et al. Distribution, translocation and accumulation of silver nanoparticles in rats. J Nanosci Nanotechnol 2009;9:4924-32
   PubMed Web of Science ®Google Scholar
• Sharma HS, Hussain S, Schlager J, et al. Influence of nanoparticles on blood-brain barrier permeability and brain edema formation in rats. Acta Neurochir 2010;106:359-64
   Google Scholar
• Tang M, Xing T, Zeng J, et al. Unmodified CdSe quantum dots induce elevation of cytoplasmic calcium levels and impairment of functional properties of sodium channels in rat primary cultured hippocampal neurons. Environ Health Perspect 2008;116(7):915-22
   PubMed Web of Science ®Google Scholar
• Hussain SM, Javorina AK, Schrand AM, et al. The interaction of manganese nanoparticles with PC-12 cells induces dopamine depletion. Toxicol Sci 2006;92:456-63
   PubMed Web of Science ®Google Scholar
• Belyanskaya L, Weigel S, Hirsch C, et al. Effects of carbon nanotubes on primary neurons and glial cellsz. Neurotoxicology 2009;30:702
   PubMed Web of Science ®Google Scholar
• Schenk M, Mueller C. The mucosal immune system at the gastrointestinal barrier. Best Pract Res Clin Gastroenterol 2008;22:391-409
   PubMed Web of Science ®Google Scholar
• Schleh C, Semmler-Behnke M, Lipka J, et al. Size and surface charge of gold nanoparticles determine absorption across intestinal barriers and accumulation in secondary target organs after oral administration. Nanotoxicology 2012;6(1):36-46
   PubMed Web of Science ®Google Scholar
• Peng Q, Zhang ZR, Sun X, et al. Mechanisms of phospholipid complex loaded nanoparticles enhancing the oral bioavailability. Mol Pharm 2010;7(2):565-75
   PubMed Web of Science ®Google Scholar
• Wiwattanapatapee R, Carreno-Gomez B, et al. Anionic PAMAM dendrimers rapidly cross adult rat intestine in vitro: a potential oral delivery system? Pharm Res 2000;17(8):991-8
   PubMed Web of Science ®Google Scholar
• Jos A, Pichardo S, Puerto M, et al. Cytotoxicity ofvcarboxylic acid functionalized single wall carbon nanotubes on the human intestinal cell line Caco-2. Toxicol In Vitro 2009;23(8):1491-6
   PubMed Web of Science ®Google Scholar
• Lai X, Blazer-Yost BL, Clack JW, et al. Protein expression profiles of intestinal epithelial co-cultures: effect of functionalised carbon nanotube exposure. Int J Biomed Nanosci Nanotechnol 2013;3:1-2
   Google Scholar
• Shvedova AA, Castranova V, Kisin ER, et al. Exposure to carbon nanotube material: assessment of nanotube cytotoxicity using human keratinocyte cells. J Toxicol Environ Health 2003;66:1909-26
   PubMed Web of Science ®Google Scholar
• Cainelli F, Vallone A. Safety and efficacy of pegylated liposomal doxorubicin in HiV-associated Kaposi's sarcoma. Biologics 2009;3:385-90
   PubMedGoogle Scholar
• Murray AR, Kisin E, Leonard SS, et al. Oxidative stress and inflammatory response in dermal toxicity of single-walled carbon nanotubes. Toxicology 2009;257(3):161-71
   PubMed Web of Science ®Google Scholar
• Cucinotto I, Fiorillo L, Gualtieri S, et al. Nanoparticle albumin bound Paclitaxel in the treatment of human cancer: nanodelivery reaches prime-time? J Drug Deliv 2013;2013:905091
   Google Scholar
• Immordino ML, Dosio F, Cattel L. Stealth liposomes: review of the basic science, rationale, and clinical applications, existing and potential. Int J Nanomedicine 2006;1(3):297-315
   PubMed Web of Science ®Google Scholar
• Salzano G, Marra M, Porru M, et al. Self-assembly nanoparticles for the delivery of bisphosphonates into tumors. Int J Pharm 2011;403(1-2):292-7
   Google Scholar
• Marra M, Salzano G, Leonetti C, et al. New self-assembly nanoparticles and stealth liposomes for the delivery of zoledronic acid: a comparative study. Biotechnol Adv 2012;30(1):302-9
   PubMed Web of Science ®Google Scholar
• Di Martino MT, Campani V, Misso G, et al. In vivo activity of miR-34a mimics delivered by stable nucleic acid lipid particles (SNALPs) against multiple myeloma. PLOS One 2014;9(2):e90005, doi:10.1371/journal.pone.0090005
   PubMed Web of Science ®Google Scholar
• Gottesman MM, Fojo T, Bates SE. Multidrug resistance in cancer: role of ATP-dependent transporters. Nat Rev Cancer 2002;2:48-58
   PubMed Web of Science ®Google Scholar