Controlled release of therapeutics using interpenetrating polymeric networks

Bibliography

• Kumar MNVR, Kumar N. Polymeric controlled drug-delivery systems: perspective issues and opportunities. Drug Dev IndPharm 2001;27(1):1–30
   PubMed Web of Science ®Google Scholar
• Sperling LH, Hu R. Interpenetrating polymer networks. In: Utracki LA, editor. Polymer blends handbook. Springer, Dordrecht; The Netherlands: 2003. p. 417–47
   Google Scholar
• Ignat L, Stanciu A. Advanced polymers: interpenetrating polymer networks. In: Kulshreshtha AK, Vasile C, editors. Handbook of polymer blends and composites. Rapra Technology Ltd, Shawbury, Sherwsbury, Shropshire, SY4 4NR, UK; 2003. 3. p. 275–80
   Google Scholar
• Kudela V. Hydrogels. In: Kroschwitz JI, editor. Encyclopedia of polymer science and engineering. Wiley; New York, NY, USA: 1987. p. 783–807
   Google Scholar
• Work WJ, Horie K, Hess M, Stepto RFT. Definitions of terms related to polymer blends, composites, and multiphase polymeric materials. Pure Appl Chem 2044;76(11):1985–2007
   Google Scholar
• Aylsworth JW. Plastic composition. US1111284A; 1914
   Google Scholar
• Millar JRJ. Interpenetrating polymer networks. Styrene-divinylbenzene copolymers with two and three interpenetrating networks, and their sulphonates. Chem Soc 1960;1311–17
   Web of Science ®Google Scholar
• Sperling LH. Interpenetrating polymer networks. In: Sperling LH, Klempner D, Utracki LA, editors. Advances in chemistry series. ACS Publications, Washington, DC, USA;1994. 239. p. 3–38
   Google Scholar
• Sperling LH, Mishra V. The current status of interpenetrating polymer net-works. In: Kim SC, Sperling L, editors. IPNs around the world: science and engineering. Wiley; New York: 1997. p. 1–25
   Google Scholar
• Dragan ES. Design and applications of interpenetrating polymer network hydrogels. A review. Chem Eng J 2014;243:572–90
   Web of Science ®Google Scholar
• Lohani A, Singh G, Bhattacharya SS. Interpenetrating polymer networks as innovative drug delivery systems. J Drug Deliv 2014;2014:ID 583612
   Google Scholar
• Sperling LH. Interpenetrating polymer networks and related materials. Plenum Press; New York: 1981
   Google Scholar
• Rokhade AP, Agnihotri SA, Aminabhavi TM, et al. Semi-interpenetrating polymer network microspheres of gelatin and sodium carboxymethyl cellulose for controlled release of ketorolac tromethamine. Carbohydr Polym 2006;65:243–52
   Web of Science ®Google Scholar
• Rokhade AP, Agnihotri SA, Aminabhavi TM. Synthesis and characterization of semi-interpenetrating microspheres of acrylamide grafted dextran and chitosan for controlled release of acyclovir. Carbohydr Polym 2007;67:605–13
   Web of Science ®Google Scholar
• Munk P, Aminabhavi TM. Introduction to macromolecular science. 2nd edition. Wiley; New York, USA: 2002
   Google Scholar
• Agnihotri SA, Mallikarjuna NN, Aminabhavi TM. Recent advances on chitosan-based micro and nanoparticles in drug delivery. J Control Release 2004;100:5–28
   PubMed Web of Science ®Google Scholar
• Murugesh S, Mandal BK. A review on interpenetrating polymer network. Int J Pharm Pharm Sci 2012;4:1–7
   Google Scholar
• Koul V, Mohamed R, Kuckling D, et al. Interpenetrating polymer network (IPN) nanogels based on gelatin and poly(acrylic acid) by inverse miniemulsion technique: synthesis and characterization. Colloids Surf B Biointerfaces 2011;83:204–13
   PubMed Web of Science ®Google Scholar
• Chapiro A. Radiation chemistry of polymeric systems. Interscience; New York: 1962. p. 22–81
   Google Scholar
• Horia MM, Nizam El-Din, Abdel Wahab M, et al. Radiation synthesis of acrylic acid/polyethyleneimine interpenetrating polymer networks (IPNs) hydrogels and its application as a carrier of atorvastatin drug for controlling cholesterol. Eur Polym J 2012;48:1632–40
   Web of Science ®Google Scholar
• Xiao W, He J, Nichol JW, et al. Synthesis and characterization of photo crosslinkable gelatin and silk fibroin interpenetrating polymer network hydrogels. Acta Biomater 2011;7:2384–93
   PubMed Web of Science ®Google Scholar
• Suri S, Schmidt CE. Photo patterned collagen-hyaluronic acid interpenetrating polymer network hydrogels. Acta Biomater 2009;5:2385–97
   PubMed Web of Science ®Google Scholar
• Wang B, Liu M, Chen Z, et al. Preparation, characterization and controlled release investigation of interpenetrating polymer networks of poly(acrylic acid)/triazole modified poly(vinyl alcohol). Int J Pharm 2007;331:19–26
   PubMed Web of Science ®Google Scholar
• Shanmugasundaram N, Ravichandran P, Reddy PN, et al. Collagen-chitosan polymeric scaffolds for the in vitro culture of human epidermoid carcinoma cells. Biomaterials 2001;22:1943–51
   PubMed Web of Science ®Google Scholar
• Tigli RS, Gumusderelioglu M. Evaluation of alginate-chitosan semi IPNs as cartilage scaffolds. J Mater Sci Mater Med 2009;20:699–709
   PubMed Web of Science ®Google Scholar
• Lee PI. Initial concentration distribution as a mechanism for regulating drug release from diffusion controlled and surface erosion controlled matrix systems. J Control Release 1986;4:1–7
   Google Scholar
• Brazel SC, Peppas NA. Modeling of drug release from swellable polymers. Eur J Pharm Biopharm 2000;49:47–8
   PubMed Web of Science ®Google Scholar
• Einmahl S, Zignani M, Varesio E, et al. Concomitant and controlled release of dexamethasone and 5-fluorouracil from poly(ortho ester). Int J Pharm 1999;185:189–98
   PubMed Web of Science ®Google Scholar
• Longley DB, Harkin DP, Johnston PG. 5-Fluorouracil: mechanisms of action and clinical strategies. Nat Rev Cancer 2003;3:330–8
   PubMed Web of Science ®Google Scholar
• Dickson JLB, Cunningham D. Systemic treatment of gastric cancer. Eur J Gastroenterol Hepatol 2004;16:255–63
   PubMed Web of Science ®Google Scholar
• Pasetto LM, Jirillo A, Stefani M, et al. Old and new drugs in systemic therapy of pancreatic cancer. Crit Rev Oncol Hematol 2004;49:135–51
   PubMed Web of Science ®Google Scholar
• Reddy KM, Ramesh Babu V, Aminabhavi TM, et al. Temperature sensitive semi-IPN microspheres from sodium alginate and N-isopropylacrylamide for controlled release of 5-fluorouracil. J Appl Polym Sci 2008;107:2820–9
   Web of Science ®Google Scholar
• Zhang J-T, Huang S-W, Cheng S-X, et al. Preparation and properties of poly(N-isopropylacrylamide)/poly(N-isopropylacrylamide) interpenetrating polymer networks for drug delivery. Polym Chem 2004;42:1249–54
   Web of Science ®Google Scholar
• Xiao Y-L, Duan G-Y, Li Y-Q, et al. Preparation of thermo-sensitive HPMC/PNIPAAm hydrogel and its controlled drug delivery of 5-fluorouracil. J Chem Eng Chin Univ 2011;25:123–8
   Google Scholar
• Varaprasad K, Vimala K, Ravindra S, et al. Biodegradable chitosan hydrogels for in vitro drug release studies of 5-flurouracil an anticancer drug. J Polym Environ 2012;20:573–82
   Web of Science ®Google Scholar
• Zhao X-Q, Wang T-X, Liu W, et al. Multifunctional Au@IPN-pNIPAAm nanogels for cancer cell imaging and combined chemo-photothermal treatment. J Mater Chem 2011;21:7240–7
   Web of Science ®Google Scholar
• Chandra Sekhar E, Krishna Rao KSV, Ramesh Raju R. Chitosan/guar gum-g-acrylamide semi IPN microspheres for controlled release studies of 5-Fluorouracil. J Appl Pharm Sci 2011;1:199–204
   Google Scholar
• El-Sherbiny IM, Lins RJ, Abdel-Bary EM, et al. Preparation, characterization, swelling and in vitro drug release behaviour of poly[N-acryloylglycine-chitosan] interpolymeric pH and thermally-responsive hydrogels. Eur Polym J 2005;41:2584–91
   Web of Science ®Google Scholar
• El-Sherbiny IM, Harding DRK, Abdel-Bary EM. Preparation and swelling study of a pH-dependent interpolymeric hydrogel based on chitosan for controlled drug release. Int J Polymeric Mater Polymeric Biomater 2006;55:789–802
   Google Scholar
• Abdelaal MY, Abdel-Razik EA, Abdel-Bary EM, et al. Chitosan-based interpolymeric pH-responsive hydrogels for in vitro drug release. J Appl Polym Sci 2007;103:2864–74
   Web of Science ®Google Scholar
• Madhusudana Rao K, Mallikarjuna B, Krishna Rao KSV, et al. Preparation and characterization of pH sensitive poly(vinyl alcohol)/sodium carboxymethyl cellulose IPN microspheres for in vitro release studies of an anticancer drug. Polym Bull 2012;68:1905–19
   Web of Science ®Google Scholar
• Krishna Rao KSV, Kiran Kumar ABV, Madhusudhan Rao K, et al. Semi-IPN hydrogels based on poly(vinyl alcohol) for controlled release studies of chemotherapeutic agent and their swelling characteristics. Polym Bull 2008;61:81–90
   Web of Science ®Google Scholar
• Liu C, Chen Y, Chen J. Synthesis and characteristics of pH-sensitive semi-interpenetrating polymer network hydrogels based on konjac glucomannan and poly(aspartic acid) for in vitro drug delivery. Carbohydr Polym 2010;79:500–6
   Web of Science ®Google Scholar
• Liu C, Gan X, Chen Y. A novel pH-sensitive hydrogels for potential colon-specific drug delivery: characterization and in vitro release studies. Starch 2011;63:503–11
   Web of Science ®Google Scholar
• Judson IR, Beale PJ, Trigo JM, et al. A human capecitabine excretion balance and pharmacokinetic study after administration of a single oral dose of 14C-labelled drug. Invest New Drugs 1999;17:49–56
   PubMed Web of Science ®Google Scholar
• Agnihotri SA, Aminabhavi TM. Formulation and evaluation of novel tableted chitosan microparticles for the controlled release of clozapine. J Microencapsul 2004;21:709–18
   PubMed Web of Science ®Google Scholar
• Agnihotri SA, Aminabhavi TM. Novel interpenetrating network chitosan-poly(ethylene oxide-g-acrylamide) hydrogel microspheres for the controlled release of Capecitabine. Int J Pharm 2006;324:103–15
   PubMed Web of Science ®Google Scholar
• Brayfield A. editor. “Doxorubicin”. Martindale: the complete drug reference. Pharmaceutical Press, London, England, UK; 2013. Retrieved 15 April 2014
   Google Scholar
• Mohamed R, Choudhary V, Koul V. Extended doxorubicin hydrochloride release from degradable gelatin-divinyl ester (DVE) interpenetrating polymer networks (IPN). Int J Pharm Pharm Sci 2011;3:20–2
   Google Scholar
• Jaiswal M, Naz F, Dinda AK, et al. In vitro and in vivo efficacy of doxorubicin loaded biodegradable semi-interpenetrating hydrogel implants of poly (acrylic acid)/gelatin for post surgical tumor treatment. Biomed Mater 2013;8:045004
   PubMed Web of Science ®Google Scholar
• Husseini GA, Christensen DA, Rapoport NY, et al. Ultrasonic release of doxorubicin from Pluronic P105 micelles stabilized with an interpenetrating network of N,N-diethylacrylamide. J Controll Release 2002;83:303–5
   PubMed Web of Science ®Google Scholar
• Kidani Y. Antitumor agents. US4169846A; 1979
   Google Scholar
• Chen Y, Ding D, Mao Z, et al. Synthesis of hydroxypropylcellulose-poly(acrylic acid) particles with semi-interpenetrating polymer network structure. Biomacromolecules 2008;9:2609–14
   PubMed Web of Science ®Google Scholar
• Gowda DV, Darshan J, Shivakumar HJ, et al. Influence of a microporous membrane coating on theophylline drug delivery. Asian Indian J Pharm Sci 2007;2:56–67
   Google Scholar
• Bhise SB, Aloorkar NH. Formulations and in vitro evaluation of floating capsules of theophylline. Indian J Pharm Sci 2008;70:224–7
   PubMed Web of Science ®Google Scholar
• Rokhade AP, Shelke NB, Aminabhavi TM, et al. Novel interpenetrating polymer network microspheres of chitosan and methylcellulose for controlled release of theophylline. Carbohydr Polym 2007;69:678–87
   Web of Science ®Google Scholar
• Sullad AG, Manjeshwar LS, Aminabhavi TM. Controlled release of theophylline from interpenetrating blend microspheres of poly(vinyl alcohol) and methyl cellulose. J Appl Polym Sci 2010;116:1226–35
   Web of Science ®Google Scholar
• Sullad AG, Manjeshwar LS, Aminabhavi TM. Polymeric blend microspheres for controlled release of theophylline. J Appl Polym Sci 2010;117:1361–70
   Web of Science ®Google Scholar
• Kajjari PB, Manjeshwar LS, Aminabhavi TM. Semi-interpenetrating polymer network hydrogel blend microspheres of gelatin and hydroxyethyl cellulose for controlled release of theophylline. Ind Eng Chem Res 2011;50:7833–40
   Web of Science ®Google Scholar
• Al-Kahtani AA, Sherigara BS. Controlled release of theophylline through semi-interpenetrating network microspheres of chitosan-(dextran-g-acrylamide). J Mater Sci Mater Med 2009;20:1437–45
   PubMed Web of Science ®Google Scholar
• Ng L, Swami S. IPNs based on chitosan with NVP and NVP/HEMA synthesised through photoinitiator-free photopolymerisation technique for biomedical applications. Carbohydr Polym 2005;60:523–8
   Web of Science ®Google Scholar
• Zhang Y, Wu F, Li M, et al. pH switching on-off semi-IPN hydrogel based on cross-linked poly(acrylamide-co-acrylic acid) and linear polyallyamine. Polymer (Guildf) 2005;46:7695–700
   Web of Science ®Google Scholar
• Krishna Rao KSV, Subha MCS, Aminabhavi TM, et al. Novel chitosan-based pH-sensitive interpenetrating network microgels for controlled release of cefadroxil. Carbohydr Polym 2006;66:333–44
   Web of Science ®Google Scholar
• Reddy KM, Ramesh Babu V, Aminabhavi TM, et al. Development of chitosan-guar gum semi-interpenetrating polymer network microspheres for controlled drug release of cefadroxil. Des Monomers Polym 2006;9:491–501
   Web of Science ®Google Scholar
• Pisal S, Zainnuddin R, Nalawade P, et al. Molecular properties of ciprofloxacin-indion 234 complexes. AAPS PharmSciTech 2004;5:84–91
   Google Scholar
• Wang Q, Dong Z, Du Y. Controlled release of ciprofloxacin hydrochloride from chitosan/polyethylene glycol blendfilms. Carbohydr Polym 2007;69:336–43
   Web of Science ®Google Scholar
• Kajjari PB, Manjeshwar LS, Aminabhavi TM. Novel interpenetrating polymer network hydrogel microspheres of chitosan and poly(acrylamide)-grafted-guar gum for controlled release of ciprofloxacin. Ind Eng Chem Res 2011;50:13280–7
   Web of Science ®Google Scholar
• Yerri Swamy B, Venkata Prasad C, Reedy CLN, et al. Interpenetrating polymer network microspheres of hydroxy propyl methyl cellulose/poly (vinyl alcohol) for control release of ciprofloxacin hydrochloride. Cellulose 2011;18:349–57
   Web of Science ®Google Scholar
• Swarnalatha S, Gopi R, Ganesh Kumar A, et al. A novel amphiphilic nano hydrogel using ketene based polyester with polyacrylamide for controlled drug delivery system. J Mater Sci Mater Med 2008;19:3005–14
   PubMed Web of Science ®Google Scholar
• Buzas GM, Szekely E. Eradication of Helicobacter pylori in peptic ulcer patients. Orv Hetil 1999;140:121–4
   PubMedGoogle Scholar
• Risbud MV, Hardikar AA, Bhat SV, et al. pH-sensitive freeze-dried chitosan-polyvinyl pyrrolidone hydrogels as controlled release system for antibiotic delivery. J Controll Release 2000;68:23–30
   PubMed Web of Science ®Google Scholar
• Ekici S, Saraydin D. Synthesis, characterization and evaluation of IPN hydrogels for antibiotic release. Drug Deliv 2004;11:381–8
   PubMed Web of Science ®Google Scholar
• Ekici S, Saraydin D. Interpenetrating polymeric network hydrogels for potential gastrointestinal drug release. Polym Int 2007;56:1371–7
   Web of Science ®Google Scholar
• Raad I, Hanna H, Maki D. Intravascular catheter-related infections: advances in diagnosis, prevention, and management. Lancet Infect Dis 2007;7:645–57
   PubMed Web of Science ®Google Scholar
• Muñoz-Muñoz F, Ruiz J-C, Alvarez-Lorenzo C, et al. Novel interpenetrating smart polymer networks grafted onto polypropylene by gamma radiation for loading and delivery of vancomycin. Eur Polym J 2009;45:1859–67
   Web of Science ®Google Scholar
• Ruiz J-C, Alvarez-Lorenzo C, Taboada P, et al. Polypropylene grafted with smart polymers (PNIPAAm/PAAc) for loading and controlled release of vancomycin. Eur J Pharm Biopharm 2008;70:467–77
   PubMed Web of Science ®Google Scholar
• Muñoz-Muñoz F, Ruiz J-C, Alvarez-Lorenzo C, et al. Temperature- and pH-sensitive interpenetrating polymer networks grafted on PP: cross-linking irradiation dose as a critical variable for the performance as vancomycin-eluting systems. Radiat Phys Chem 2012;81:531–40
   Web of Science ®Google Scholar
• Tripathi KD. Essentials of medical pharmacology. 4th edition. Jaypee Brothers Medical Publication, New Delhi; 2002
   Google Scholar
• Kulkarni PV, Keshavayya J. Chitosan-sodium alginate biodegradable interpenetrating polymer network (IPN) beads for delivery of ofloxacin hydrochloride. Int J Pharm Pharm Sci 2010;2:77–82
   Web of Science ®Google Scholar
• Gupta AK, Siddiqui AW, Datta MS, et al. Interpenetrating polymeric network hydrogel for stomach-specific drug delivery of clarithromycin: preparation and evaluation. Asian J Pharm 2010;4:179–84
   Google Scholar
• Wahlig H, Dingeldein E. Antibiotics and bone cement; experimental and clinical long-term observations. Acta Orthop Scand 1980;51:49–56
   PubMedGoogle Scholar
• Changez M, Burugapalli K, Koul V, et al. The effect of composition of poly(acrylic acid)-gelatin hydrogel on gentamicin sulphate release: in vitro. Biomaterials 2003;24:527–36
   PubMed Web of Science ®Google Scholar
• Changez M, Koul V, Dinda AK, et al. Efficacy of antibiotics-loaded interpenetrating network (IPNs) hydrogel based on poly(acrylic acid) and gelatin for treatment of experimental osteomyelitis: in vivo study. Biomaterials 2005;26:2095–104
   PubMed Web of Science ®Google Scholar
• Changez M, Koul V, Burugapalli K, et al. Studies on biodegradation and release of gentamicin sulphate from interpenetrating network hydrogels based on poly(acrylic acid) and gelatin: in vitro and in vivo. Biomaterials 2004;25:139–46
   PubMed Web of Science ®Google Scholar
• Bhaskaran S, Suresh S. Biodegradable microspheres of ketorolac tromethamine for parenteral administration. J Microencapsul 2004;21:743–50
   PubMed Web of Science ®Google Scholar
• Rokhade AP, Agnihotri SA, Aminabhavi TM, et al. Semi-Interpenetrating polymer network microspheres of gelatin and sodium carboxymethyl cellulose for the controlled release of ketorolac tromethamine. Carbohydr Polym 2006;65:243–52
   Web of Science ®Google Scholar
• Sallmann AR. The history of diclofenac. Am J Med 1986;80:29–33
   PubMed Web of Science ®Google Scholar
• Kurkuri MD, Aminabhavi TM. Poly(vinyl alcohol) and poly(acrylic acid) sequential interpenetrating network pH-sensitive microspheres for the delivery of diclofenac sodium to the intestine. J Control Release 2004;96:9–20
   PubMed Web of Science ®Google Scholar
• Banerjee S, Chaurasia G, Pal D, et al. Investigation on crosslinking density for development of novel interpenetrating polymer network (IPN) based formulation. J Sci Ind Res 2010;69:777–84
   Web of Science ®Google Scholar
• Ahmed A-K, Naik HSB, Sherigara BS. Synthesis and characterization of chitosan-based pH-sensitive semi-interpenetrating network microspheres for controlled release of diclofenac sodium. Carbohydr Res 2009;344:699–706
   PubMed Web of Science ®Google Scholar
• Ray S, Banerjee S, Maiti S, et al. Novel interpenetrating network microspheres of xanthan gum-poly(vinyl alcohol) for the delivery of diclofenac sodium to the intestine in vitro and in vivo evaluation. Drug Deliv 2010;17:508–19
   PubMed Web of Science ®Google Scholar
• Bhattacharya SS, Ghosha AK, Banerjee S, et al. Al3+ ion cross-linked interpenetrating polymeric network microbeads from tailored natural polysaccharides. Int J Biol Macromol 2012;51:1173–84
   PubMed Web of Science ®Google Scholar
• Banerjee S, Siddiqui L, Bhattacharya SS, et al. Interpenetrating polymer network (IPN) hydrogel microspheres for oral controlled release application. Int J Biol Macromol 2012;50:198–206
   PubMed Web of Science ®Google Scholar
• Zhao Y, Chen G, Sun M, et al. Study on preparation of the pH sensitive hydroxyethyl chitin/poly (acrylic acid) hydrogel and its drug release property. J Biomed Eng 2006;23:338–41
   Google Scholar
• Shipton EA. Tramadol-present and future. Anaesth Intensive Care 2000;28:363–74
   PubMed Web of Science ®Google Scholar
• Kumar P, Singh I. Formulation and characterization of tramadol-loaded IPN microgels of alginate and gelatin: optimization using response surface methodology. Acta Pharm 2010;60:295–310
   PubMed Web of Science ®Google Scholar
• Jones JCV, Smith J, Jones DR. A comparison in general practice of once and twice daily sustained-release ibuprofen and standard ibuprofen in the treatment of non-articular rheumatism. Br J Clin Pract 1984;38:353–8
   PubMedGoogle Scholar
• Kantor TH. Ibuprofen. Ann Intern Med 1979;91:877–82
   PubMed Web of Science ®Google Scholar
• Ray R, Pal R, Karan S, et al. Evaluation of pharmacological activities of ibuprofen loaded interpenetrating polymer Network (IPN) beads from sodium carboxymethyl xanthan and sodium alginate on rats. Pharmacol Online 2010;2:719–36
   Google Scholar
• Ray R, Maity S, Mandal S, et al. Studies on the release of ibuprofen from Al3+ ion cross-linked homopolymeric and interpenetrating network hydrogel beads of carboxymethyl xanthan and sodium alginate. Adv Polym Technol 2011;30:1–11
   Web of Science ®Google Scholar
• Huang Y, Liu M, Wang L, et al. A novel triple-responsive poly(3-acrylamidephenylboronic acid-co-2-(dimethylamino) ethyl methacrylate)/(β-cyclodextrin-epichlorohydrin)hydrogels: Synthesis and controlled drug delivery. React Funct Polym 2011;71:666–73
   Web of Science ®Google Scholar
• Wang Q, Li S, Wang Z, et al. Preparation and characterization of a positive thermoresponsive hydrogel for drug loading and release. J Appl Polym Sci 2009;111:1417–25
   Web of Science ®Google Scholar
• Babu VR, Krishna Rao KSV, Aminabhavi TM, et al. pH sensitive interpenetrating network microgels of sodium alginate-acrylic acid for the controlled release of ibuprofen. J Appl Polym Sci 2006;99:2671–8
   Web of Science ®Google Scholar
• Rama Rao P, Diwan PV. Formulation and in vitro evaluation of polymeric films of diltiazem hydrochloride and indomethacin for transdermal administration. Drug Dev Ind Pharm 1998;24:327–36
   PubMed Web of Science ®Google Scholar
• Deng K, Gou Y, Zuo J, et al. A pH/temperature-sensitive semi-IPN bead for drug release carrier. Adv Mater Res 2010;148-149:1449–52
   Google Scholar
• Shi J, Alves NM, Mano JF. Drug release of pH/temperature-responsive calcium alginate/poly(N-isopropylacrylamide) semi-IPN beads. Macromol Biosci 2006;6:358–63
   PubMed Web of Science ®Google Scholar
• Ramesh Babu V, Sairam M, Aminabhavi TM. Preparation and characterization of novel semi-interpenetrating 2-hydroxyethylmethacrylate-g-chitosan copolymeric microspheres for sustained release of indomethacin. J Appl Polym Sci 2007;106:3778–85
   Web of Science ®Google Scholar
• Solak EK. Preparation and characterization of IPN microspheres for controlled delivery of naproxen. J Biomater Nanobiotechnol 2011;2:445–53
   Google Scholar
• Kulkarni RV, Boppana R, Mohan GK, et al. pH-responsive interpenetrating network hydrogel beads of poly(acrylamide)-g-carrageenan and sodium alginate for intestinal targeted drug delivery: Synthesis, in vitro and in vivo evaluation. J Colloid Interface Sci 2012;367:509–17
   PubMed Web of Science ®Google Scholar
• Huang SJ, Wang JM, Tseng SC, et al. Controlled immobilization of chondroitin sulfate in polyacrylic acid networks. J Biomater Sci Polym Ed 2007;18:17–34
   PubMed Web of Science ®Google Scholar
• Kulkarni RV, Sa B. Novel pH-sensitive interpenetrating network hydrogel beads of carboxymethylcellulose-(polyacrylamide-grafted-alginate) for controlled release of ketoprofen: preparation and characterization. Curr Drug Deliv 2008;5:256–64
   PubMedGoogle Scholar
• Kulkarni RV, Sa B. Evaluation of pH-sensitivity and drug release characteristics of (polyacrylamide-grafted-xanthan)-carboxymethyl cellulose-based pH-sensitive interpenetrating network hydrogel beads. Drug Dev Ind Pharm 2008;34:1406–14
   PubMed Web of Science ®Google Scholar
• Wang LF, Wang JM, Chiang YL. Insolubilization of sodium chondroitin sulfate by forming a semi-interpenetrating polymer network with acrylic acid: a potential carrier for colon-specific drug delivery. J Appl Polym Sci 2002;85:114–22
   Web of Science ®Google Scholar
• Mariappan TT, Singh S. Regional gastrointestinal permeability of rifampicin and isoniazid (alone and their combination) in the rat. Int J Tuberc Lung Dis 2003;7:797–803
   PubMed Web of Science ®Google Scholar
• Rastogi R, Sultana Y, Aqil M, et al. Alginate microspheres of isoniazid for oral sustained drug delivery. Int J Pharm 2007;334:71–7
   PubMed Web of Science ®Google Scholar
• Angadi SC, Manjeshwar LS, Aminabhavi TM. Stearic acid-coated chitosan-based interpenetrating polymer network microspheres: controlled release characteristics. Ind Eng Chem Res 2011;50:4504–14
   Web of Science ®Google Scholar
• Angadi SC, Manjeshwar LS, Aminabhavi TM. Interpenetrating polymer network blend microspheres of chitosan and hydroxyethyl cellulose for controlled release of isoniazid. Int J Biol Macromol 2010;47:171–9
   PubMed Web of Science ®Google Scholar
• Xing Z, Wang C, Yan J, et al. Dual stimuli responsive hollow nanogels with IPN structure for temperature controlling drug loading and pH triggering drug release. Soft Matter 2011;7:992–7997
   Google Scholar
• Gupta KC, Ravi Kumar MNV. pH dependent hydrolysis and drug release behavior of chitosan/poly(ethylene glycol) polymer network microspheres. J Mater Sci Mater Med 2001;12:753–9
   PubMed Web of Science ®Google Scholar
• Gupta KC, Ravi Kumar MNV. Studies on semi-interpenetrating polymer network beads of chitosan–poly(ethylene glycol) for the controlled release of drugs. J Appl Polym Sci 2001;80:39–649
   Google Scholar
• Mundargi RC, Shelke NB, Aminabhavi TM, et al. Novel thermoresponsive semi-interpenetrating network microspheres of gellan gum-poly(N-isopropylacrylamide) for controlled release of atenolol. J Appl Polym Sci 2010;116:1832–41
   Web of Science ®Google Scholar
• McTavish D, Campoli-Richards D, Sorkin EM, Carvedilol A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy. Drugs 1993;45:232–58
   PubMed Web of Science ®Google Scholar
• Agnihotri SA, Aminabhavi TM. Development of novel interpenetrating network gellan gum-poly(vinyl alcohol) hydrogel microspheres for the controlled release of carvedilol. Drug Dev Ind Pharm 2005;31:491–503
   PubMed Web of Science ®Google Scholar
• Sweetman SC. Martindale. In: The complete drug reference. 33rd edition. Pharmaceutical Press; London, UK: 2002. p. 874
   Google Scholar
• Watts PJ, Illum L. Colonic drug absorption and delivery. Drug Develop Ind Pharm 1997;23:893–913
   Web of Science ®Google Scholar
• Ray D, Gils PS, Mohanta GP, et al. Comparative delivery of Diltiazem hydrochloride through synthesized polymer: hydrogel and hydrogel microspheres. J Appl Polym Sci 2010;116:959–68
   Web of Science ®Google Scholar
• Mandal S, Basu SK, Sa B. Ca2+ ion cross-linked interpenetrating network matrix tablets of polyacrylamide-grafted-sodium alginate and sodium alginate for sustained release of diltiazem hydrochloride. Carbohydr Polym 2010;82:867–73
   Web of Science ®Google Scholar
• Kulkarni RV, Mangond BS, Mutalik S, et al. Interpenetrating polymer network microcapsules of gellan gum and egg albumin entrapped with diltiazem–resin complex for controlled release application. Carbohydr Polym 2011;83:1001–7
   Web of Science ®Google Scholar
• Kulkarni RV, Mutalik S, Mangond BS, et al. Novel interpenetrated polymer network microbeads of natural polysaccharides for modified release of water soluble drug: in vitro and in vivo evaluation. J Pharm Pharmacol 2012;64:530–40
   PubMed Web of Science ®Google Scholar
• Kulkarni RV, Baraskar VV, Alange VV, et al. Controlled release of an antihypertensive drug through interpenetrating polymer network hydrogel tablets of tamarind seed polysaccharide and sodium alginate. J Macromol Sci Part B Phys 2013;52:1636–50
   Web of Science ®Google Scholar
• Kulkarni RV, Baraskar VV, Setty CM, et al. Interpenetrating polymer network matrices of sodium alginate and carrageenan for controlled drug delivery application. Fibers Polym 2011;12:352–8
   Web of Science ®Google Scholar