Are rats the appropriate experimental model to understand age-related renal drug metabolism and toxicity?

Bibliography

• Goldstein RS, Tarloff JB, Hook JB. Age-related nephropathy in laboratory rats. FASEB J 1988;2:2241-51
   PubMed Web of Science ®Google Scholar
• Zoetis T, Hurtt ME. Species comparison of anatomical and functional renal development. Birth Defects Res B 2003;68:111-20
   PubMed Web of Science ®Google Scholar
• Lazarou J, Pomeranz BH, Corey PN. Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. J Am Med Assoc 1998;15:1200-5
   Google Scholar
• Olin SS. Research needs: recommendations of an ILSI Working Group on age-related differences in susceptibility. Food Addit Contam 1998;15:53-4
   PubMed Web of Science ®Google Scholar
• Pirmohamed M, Breckenridge AM, Kitteringham NR, Park BK. Adverse drug reactions: current status. Br Med J 1998;316:1295-8
   PubMed Web of Science ®Google Scholar
• Faustman EM, Silbernagel SM, Fenske RA, Mechanisms underlying children's susceptibility to environmental toxicants. Environ Health Perspect 2000;108(Suppl 1):13-21
   PubMed Web of Science ®Google Scholar
• Espandiari P, Zhang J, Rosenzweig BA, The utility of a rodent model in detecting pediatric drug-induced nephrotoxicity. Toxicol Sci 2007;99:637-48
   PubMed Web of Science ®Google Scholar
• Espandiari P, Zhang J, Schnackenberg LK, Age-related differences in susceptibility to toxic affects of valproic acid in rats. J Appl Toxicol 2008;28:628-37
   PubMed Web of Science ®Google Scholar
• Espandiari P, Rosenzweig B, Zhang J, Age-related differences in susceptibility to cisplatin-induced renal toxicity. J Appl Toxicol 2010;30:172-82
   PubMed Web of Science ®Google Scholar
• Chen G, Bridenbaugh EA, Akintola AD, Increased susceptibility of aging kidney to ischemic injury: identification of candidate genes changed during aging, but corrected by caloric restriction. Am J Physiol Renal Physiol 2007;293:F1271-81
   Google Scholar
• Ichimura T, Hung CC, Yang SA, Kidney injury molecule-1: a tissue and urinary biomarker for nephrotoxicant-induced renal injury. Am J Physiol Renal Physiol 2004;286:F552-63
   PubMed Web of Science ®Google Scholar
• Owen RA, Heywood R. Age-related variations in renal structure and function in Sprague-Dawley rats. Toxicol Pathol 1986;14:158-67
   PubMedGoogle Scholar
• Elema JD, Arends A. Focal and segmental glomerular hyalinosis and sclerosis in the rat. Lab Invest 1975;33:554-61
   PubMed Web of Science ®Google Scholar
• Hirokawa K. Characterization of age-associated kidney disease in Wistar rats. Mech Ageing Dev 1975;4:301-16
   PubMed Web of Science ®Google Scholar
• Bolton WK, Benton FR, Maclay JG, Sturgill BC. Spontaneous glomerular sclerosis in aging Sprague-Dawley rats. I. Lesions associated with mesangial IgM deposits. Am J Pathol 1976;85:277-302
   PubMed Web of Science ®Google Scholar
• Haley DP, Bulger RE. The aging male rat: structure and function of the kidney. Am J Anat 1983;167:1-13
   PubMedGoogle Scholar
• Hard GC, Khan KN. A contemporary overview of chronic progressive nephropathy in the laboratory rat, and its significance for human risk assessment. Toxicol Pathol 2004;32:171-80
   PubMed Web of Science ®Google Scholar
• Fleck C. Determination of the glomerular filtration rate (GFR): methodological problems, age-dependence, consequences of various surgical interventions, and the influence of different drugs and toxic substances. Physiol Res 1999;48:267-79
   PubMed Web of Science ®Google Scholar
• Inserra F, Basso N, Ferder M, Changes seen in the aging kidney and the effect of blocking the renin-angiotensin system. Ther Adv Cardiovasc Dis 2009;3:341-6
   PubMedGoogle Scholar
• Hard GC, Johnson KJ, Cohen SM. A comparison of rat chronic progressive nephropathy with human renal disease. Implications for human risk assessment. Crit Rev Toxicol 2009;39:332-46
   PubMed Web of Science ®Google Scholar
• Kelly SJ, Bonthius DJ, West JR. Developmental changes in alcohol pharmacokinetics in rats. Alcohol Clin Exp Res 1987;11:281-6
   PubMed Web of Science ®Google Scholar
• Stewart CF, Hampton EM. Effect of maturation on drug disposition in pediatric patients. Clin Pharm 1987;6:548-64
   PubMedGoogle Scholar
• Jose PA, Fildes RD, Gomez RA, Neonatal renal function and physiology. Curr Opin Pediatr 1994;6:172-7
   PubMedGoogle Scholar
• Lindeman RD. Changes in renal function with aging. Implications for treatment. Drugs Aging 1992;2:423-31
   PubMed Web of Science ®Google Scholar
• Lumbers ER. Development of renal function in the fetus: a review. Reprod Fertil Dev 1995;7:415-26
   PubMed Web of Science ®Google Scholar
• Belichenko VM, Grigorieva TA, Shyyrapai UV, Dynamics of organ blood flow in rats in postnatal ontogenesis. J Evol Biochem Physiol 2009;45:246-51
   Web of Science ®Google Scholar
• Morselli PL, Franco-Morselli R, Bossi L. Clinical pharmacokinetics in newborns and infants: age-related differences and therapeutic implications. Clin Pharmacokinet 1980;5:485-527
   PubMed Web of Science ®Google Scholar
• Milsap RL, Jusko WJ. Pharmacokinetics in the infant. Environ Health Perspect 1994;102(Suppl 1):107-10
   PubMedGoogle Scholar
• Shimada T, Yamazaki H, Mimura M, Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J Pharmacol Exp Ther 1994;270:414-23
   PubMed Web of Science ®Google Scholar
• Cresteil T. Onset of xenobiotic metabolism in children: toxicological implications. Food Addit Contam 1998;15(Suppl):45-51
   PubMedGoogle Scholar
• Horbach GJMJ, Van Asten JG, Van Bezooijen CFA. The influence of age on the inducibility of rat liver cytochrome P450IA1 (CYPIA1) and P450IA2 (CYPIA2) mRNAs. Mutat Res 1990;237:117-21
   PubMed Web of Science ®Google Scholar
• McMartin DN, O'Connor JA Jr, Fasco MJ, Kaminski LS. Influence of aging and induction on rat liver and kidney microsomal mixed function oxidase systems. Toxicol Appl Pharmacol 1980;54:411-19
   PubMed Web of Science ®Google Scholar
• Dutton GJ. Developmental aspects of drug conjugation, with special reference to glucuronidation. Annu Rev Pharmacol Toxicol 1978;18:17-35
   PubMed Web of Science ®Google Scholar
• McRorie TI, Lynn AM, Nespeca MK, The maturation of morphine clearance and metabolism. Am J Dis Child 1992;146:972-6
   PubMedGoogle Scholar
• Morgado N, Sanhueza J, Nieto S, Valenzuela A. Effects of the degree of hydrogrnation of fish oil on the enzymatic activity and on the fatty acid composition of hepatic microsomes from young and aged rats. Ann Nutr Metab 2003;47:124-31
   PubMed Web of Science ®Google Scholar
• Meng Q, Wong YT, Chen J, Ruan R. Age-related changes in mitochondrial function and antioxidative enzyme activity in Fischer 344 rats. Mech Ageing Dev 2007;128:286-92
   PubMed Web of Science ®Google Scholar
• Maher P. The effects of stress and aging on glutathione metabolism. Ageing Res Rev 2005;4:288-314
   PubMed Web of Science ®Google Scholar
• Mallikarjuna K, Nishanth K, Sathyavelu Reddy K. Hepatic glutathione mediated antioxidant system in ethanol treated rats: decline with age. Pathophysiology 2007;14:17-21
   PubMedGoogle Scholar
• Appenroth D, Winnefeld K. Role of glutathione for cisplatin nephrotoxicity in young and adult rats. Ren Fail 1993;15:135-9
   PubMed Web of Science ®Google Scholar
• Travis LB. The kidney and urinary. In: Rudolph AM, editor, Pediatrics. 19th edition. Appleton and Lange, Norwalk; 1991. p. 1223-36
   Google Scholar
• Buist SCN, Cherrington NJ, Choudhuri S, Gender-specific and developmental influences on the expression of rat organic anion transporters. J Pharmacol Exp Ther 2002;301:145-51
   PubMed Web of Science ®Google Scholar
• Fanos V, Dall'Agnola A. Antibiotics in neonatal infection. Drugs 1999;58:405-27
   PubMed Web of Science ®Google Scholar
• Appenroth D, Winnefeld K, Braunlich H. Nephrotoxicity and pharmacokinetics of cisplatinum in young and adult rats. Biomed Biochim Acta 1988;47:791-7
   PubMedGoogle Scholar
• Namikawa K, Kinsoku A, Minami T, Relationship between age and nephrotoxicity following single low-dose cisplatin (CDDP) injection in rats. Biol Pharm Bull 1995;18:957-62
   PubMed Web of Science ®Google Scholar
• Ali BH, Al-Moundhri M, Tageldin M, Ontogenic aspects of cisplatin-induced nephrotoxicity in rats. Food Chem Toxicol 2008;46:3355-8
   PubMed Web of Science ®Google Scholar
• de la Torre A, Granero S, Mayayo E, Effect of age on vanadium nephrotoxicity in rats. Toxicol Lett 1999;105:75-82
   PubMed Web of Science ®Google Scholar
• Appenroth D. Ontogenetic changes in the nephrotoxicity of chromate correlate with the glutathione oxidoreductase system. J Trace Elem Electrolytes Health Dis 1994;8:33-6
   PubMedGoogle Scholar
• Chiusolo A, Defazio R, Casartelli A, Regucalcin down-regulation in rat kidney tissue after treatment with nephrotoxicants. Toxicol Lett 2008;182:84-90
   PubMed Web of Science ®Google Scholar
• Zanetti E, Chiusolo A, Defazio R, Evaluation of aging influence on renal toxicity caused by segment-specific nephrotoxicants of the proximal tubule in rat. J Appl Toxicol 2010;30:142-50
   PubMed Web of Science ®Google Scholar
• Appenroth D, Tiller S, Gambaryan S, Ontogenetic aspects of thallium-induced nephrotoxicity in rats. J Appl Toxicol 1996;16:235-43
   PubMed Web of Science ®Google Scholar
• Kociba RJ, Schwetz BA, Keyes DG, Chronic toxicity and reproduction studies of hexachlorobutadiene in rats. Environ Health Perspect 1977;21:49-53
   PubMed Web of Science ®Google Scholar
• Kuo C-H, Hook JB. Effects of age and sex on hexachloro-1,3-butadiene toxicity in the Fischer-344 rat. Life Sci 1983;33:517-23
   PubMed Web of Science ®Google Scholar
• Hook JB, Ishmael J, Lock EA. Nephrotoxicity of hexachloro-1:3-butadiene in the rat: the effect of age, sex, and strain. Toxicol Appl Pharmacol 1983;67:122-31
   PubMed Web of Science ®Google Scholar
• Trevisan A, Meneghetti P, Maso S, Sex- and age-related nephrotoxicity due to 1,2-dichloropropane in vitro. Arch Toxicol 1992;66:641-5
   PubMed Web of Science ®Google Scholar
• Dekant W, Vamvakas S. Biotransformation and membrane transport in nephrotoxicity. Crit Rev Toxicol 1996;26:309-34
   PubMed Web of Science ®Google Scholar
• Appenroth D, Rost M, Friedrich M, Schulz O. Contribution to the mechanism of chromate nephrotoxicity in developing rats: EPR investigations. Arch Toxicol 1996;71:25-30
   PubMed Web of Science ®Google Scholar
• Jacquillet G, Barbier O, Rubera I, Cadmium causes delayed effects on renal function in the offspring of cadmium-contaminated pregnant female rats. Am J Physiol Renal Physiol 2007;293:F1450-60
   PubMed Web of Science ®Google Scholar
• Davis M, Berndt WO, Mehendale H. Disposition and nephrotoxicity of hexachloro-1:3-butadiene. Toxicology 1980;16:179-91
   PubMed Web of Science ®Google Scholar
• Gray JE. Chronic progressive nephrosis in the albino rat. Crit Rev Toxicol 1977;5:115-44
   Web of Science ®Google Scholar
• Kyle ME, Kocsis JJ. The effect of age on salicylate-induced nephrotoxicity in male rats. Toxicol Appl Pharmacol 1985;81:337-47
   PubMed Web of Science ®Google Scholar
• Goldstein RS, Pasino DA, Hook JB. Cephaloridine nephrotoxicity in aging male Fischer-344 rats. Toxicology 1986;38:43-53
   PubMed Web of Science ®Google Scholar
• Beierschmitt WP, Keenan KP, Weiner M. Age-related increased susceptibility of male Fischer 344 rats to acetaminophen nephrotoxicity. Life Sci 1986;39:2335-42
   PubMed Web of Science ®Google Scholar
• Wormser U, Nir I. Effect of age on cadmium-induced metallothionein synthesis in the rat. Arch Toxicol 1988;62:392-4
   PubMed Web of Science ®Google Scholar
• Tarloff JB, Khairallah EA, Cohen SD, Goldstein RS. Sex- and age-dependent acetaminophen hepato- and nephrotoxicity in Sprague-Dawley rats: role of tissue accumulation, nonprotein sulphydryl depletion, and covalent binding. Fundam Appl Toxicol 1996;30:13-22
   PubMedGoogle Scholar
• Peters-Volleberg GWM, Dortant PM, Speijers GJA. Comparison of tobramycin nephrotoxicity in young adult and aged female rats. Pharmacol Toxicol 1999;84:147-53
   PubMedGoogle Scholar
• Brenner BM. Nephron adaptation to renal injury or ablation. Am J Physiol 1985;249:F324-37
   PubMed Web of Science ®Google Scholar
• Yu BP. Aging and oxidative stress: modulation by dietary restriction. Free Radic Biol Med 1996;21:97-105
   PubMedGoogle Scholar
• Son TG, Zou Y, Yu BP, Aging effect on myeloproxidase in rat kidney and its modulation by caloric restriction. Free Radic Res 2005;39:283-9
   PubMed Web of Science ®Google Scholar
• Lee JH, Jung KJ, Kim JW. Suppression of apoptosis by caloric restriction in aged kidney. Exp Gerontol 2004;39:1361-8
   PubMed Web of Science ®Google Scholar
• Glassok RJ. The GFR decline with aging: a sign of normal senescence, not disease. Nephrol Times 2009;2:6-8
   Google Scholar
• Roels HA, Lauwerys RR, Buchet JP, Health significance of cadmium induced renal dysfunction: a five year follow up. Br J Ind Med 1989;46:755-64
   PubMedGoogle Scholar