Ontogeny of oral drug absorption processes in children

Bibliography

• Schirm E, Tobi H, de Vries TW, Lack of appropriate formulations of medicines for children in the community. Acta Paediatr 2003;92(12):1486-9
   PubMed Web of Science ®Google Scholar
• Atkinson AJ, Abernethy DR, Daniels CE, Drug absorption and bioavailability. In: Principles of clinical pharmacology. 2nd edition. Academic Press; Burlington USA; 2007. p 37-58
   Google Scholar
• Martinez MN, Amidon GL. A mechanistic approach to understanding the factors affecting drug absorption: a review of fundamentals. J Clin Pharmacol 2002;42(6):620-43
   PubMed Web of Science ®Google Scholar
• Kearns GL, Abdel-Rahman SM, Alander SW, Developmental pharmacology–drug disposition, action, and therapy in infants and children. N Engl J Med 2003;349(12):1157-67
   PubMed Web of Science ®Google Scholar
• Jacqz-Aigrain E. Drug policy in Europe Research and funding in neonates: current challenges, future perspectives, new opportunities. Early Hum Dev 2011;87(Suppl 1):S27-30
   PubMed Web of Science ®Google Scholar
• FDA. U.S. Food and Drug Administration. Available from: http://www.fda.gov/ScienceResearch/SpecialTopics/PediatricTherapeuticsResearch/default.htm
   Google Scholar
• Hines RN, McCarver DG. The ontogeny of human drug-metabolizing enzymes: phase I oxidative enzymes. J Pharmacol Exp Ther 2002;300(2):355-60
   PubMed Web of Science ®Google Scholar
• Smits A, Kulo A, de Hoon JN, Allegaert K. Pharmacokinetics of drugs in neonates: pattern recognition beyond compound specific observations. Curr Pharm Des 2012. [Epub ahead of print]
   Web of Science ®Google Scholar
• Strolin Benedetti M, Whomsley R, Baltes EL. Differences in absorption, distribution, metabolism and excretion of xenobiotics between the paediatric and adult populations. Expert Opin Drug Metab Toxicol 2005;1(3):447-71
   PubMedGoogle Scholar
• Yokoi T. Essentials for starting a pediatric clinical study (1): pharmacokinetics in children. J Toxicol Sci 2009;34(Suppl 2):SP307-12
   PubMed Web of Science ®Google Scholar
• Bowles A, Keane J, Ernest T, Specific aspects of gastro-intestinal transit in children for drug delivery design. Int J Pharm 2010;395(1-2):37-43
   PubMedGoogle Scholar
• Datta S, Houle GL, Fox GS. Concentration of lidocaine hydrochloride in newborn gastric fluid after elective caesarean section and vaginal delivery with epidural analgesia. Can Anaesth Soc J 1975;22(1):79-83
   PubMedGoogle Scholar
• Whetstine LJ, Hulsey TC, Annibale DJ, Pittard WB. Supplemental oxygen and gastric pH in unfed preterm infants. South Med J 1995;88(4):458-61
   PubMed Web of Science ®Google Scholar
• Miller RA. Observations on the gastric acidity during the first month of life. Arch Dis Child 1941;16(85):22-30
   PubMedGoogle Scholar
• Cote CJ, Goudsouzian NG, Liu LM, Assessment of risk factors related to the acid aspiration syndrome in pediatric patients-gastric ph and residual volume. Anesthesiology 1982;56(1):70-2
   PubMed Web of Science ®Google Scholar
• Goresky GV, Finley GA, Bissonnette B, Shaffer EA. Efficacy, duration, and absorption of a paediatric oral liquid preparation of ranitidine hydrochloride. Can J Anaesth 1992;39(8):791-8
   PubMed Web of Science ®Google Scholar
• Jahr JS, Burckart G, Smith SS, Effects of famotidine on gastric pH and residual volume in pediatric surgery. Acta Anaesthesiol Scand 1991;35(5):457-60
   PubMed Web of Science ®Google Scholar
• Kelly EJ, Chatfield SL, Brownlee KG, The effect of intravenous ranitidine on the intragastric pH of preterm infants receiving dexamethasone. Arch Dis Child 1993;69(1 Spec No):37-9
   PubMed Web of Science ®Google Scholar
• Kelly EJ, Newell SJ, Brownlee KG, Gastric acid secretion in preterm infants. Early Hum Dev 1993;35(3):215-20
   PubMed Web of Science ®Google Scholar
• Kraus G, Krishna DR, Chmelarsch D, Famotidine. Pharmacokinetic properties and suppression of acid secretion in paediatric patients following cardiac surgery. Clin Pharmacokinet 1990;18(1):77-81
   PubMed Web of Science ®Google Scholar
• Maekawa N, Mikawa K, Yaku H, Effects of 2-, 4- and 12-h fasting intervals on preoperative gastric fluid pH and volume, and plasma glucose and lipid homeostasis in children. Acta Anaesthesiol Scand 1993;37(8):783-7
   PubMed Web of Science ®Google Scholar
• Miller BR, Tharp JA, Issacs WB. Gastric residual volume in infants and children following a 3-h fast. J Clin Anesth 1990;2(5):301-5
   PubMedGoogle Scholar
• Nishina K, Mikawa K, Maekawa N, Omeprazole reduces preoperative gastric fluid acidity and volume in children. Can J Anaesth 1994;41(10):925-9
   PubMed Web of Science ®Google Scholar
• Oderda G, Rapa A, Chiorboli E, Measurement of postprandial changes in urine acid output to detect changes of gastric acid secretion after proton pump inhibitors in children. Dig Dis Sci 2002;47(8):1843-9
   PubMed Web of Science ®Google Scholar
• Omari TI, Davidson GP. Multipoint measurement of intragastric pH in healthy preterm infants. Arch Dis Child Fetal Neonatal Ed 2003;88(6):F517-20
   PubMed Web of Science ®Google Scholar
• Rogers IM, Drainer IK, Moore MR, Buchanan KD. Plasma gastrin in congenitial hypertrophic pyloric stenosis. A hypothesis disproved. Arch Dis Child 1975;50(6):467-71
   PubMed Web of Science ®Google Scholar
• Smith LJ, Kaminsky S, D'Souza SW. Neonatal fat digestion and lingual lipase. Acta Paediatr Scand 1986;75(6):913-18
   PubMed Web of Science ®Google Scholar
• Splinter WM, Schaefer JD. Unlimited clear fluid ingestion two hours before surgery in children does not affect volume or pH of stomach contents. Anaesth Intensive Care 1990;18(4):522-6
   PubMed Web of Science ®Google Scholar
• Splinter WM, Stewart JA, Muir JG. Large volumes of apple juice preoperatively do not affect gastric pH and volume in children. Can J Anaesth 1990;37(1):36-9
   PubMed Web of Science ®Google Scholar
• Yildiz F, Tryba M, Kuehn K, Hausdoerfer J. Reduction of gastric acid secretion. The efficacy of pre-anaesthetic oral cimetidine in children. Anaesthesia 1984;39(4):314-18
   PubMed Web of Science ®Google Scholar
• Lopez-Alonso M, Moya MJ, Cabo JA, Twenty-four-hour esophageal impedance-pH monitoring in healthy preterm neonates: rate and characteristics of acid, weakly acidic, and weakly alkaline gastroesophageal reflux. Pediatrics 2006;118(2):e299-308
   Google Scholar
• Omari TI, Haslam RR, Lundborg P, Davidson GP. Effect of omeprazole on acid gastroesophageal reflux and gastric acidity in preterm infants with pathological acid reflux. J Pediatr Gastroenterol Nutr 2007;44(1):41-4
   PubMed Web of Science ®Google Scholar
• Demir H, Ozen H, Kocak N, Does simultaneous gastric and esophageal pH monitoring increase the diagnosis of gastroesophageal reflux disease? Turk J Pediatr 2005;47(1):14-16
   PubMed Web of Science ®Google Scholar
• Kleinman RE, Goulet OJ, Mieli-Vergani G, Walker's pediatric gastrointestinal disease. People's Medical Publishing House; Shelton, CT: 2008
   Google Scholar
• Boyle JT. Acid secretion from birth to adulthood. J Pediatr Gastroenterol Nutr 2003;37(Suppl 1):S12-16
   Google Scholar
• Huang NN, High RH. Comparison of serum levels following the administration of oral and parenteral preparations of penicillin to infants and children of various age groups. J Pediatr 1953;42(6):657-8
   PubMed Web of Science ®Google Scholar
• Hoekstra JH, van den Aker JH, Kneepkens CM, Evaluation of 13CO2 breath tests for the detection of fructose malabsorption. J Lab Clin Med 1996;127(3):303-9
   PubMedGoogle Scholar
• Perri F, Pastore M, Zicolella A, Gastric emptying of solids is delayed in celiac disease and normalizes after gluten withdrawal. Acta Paediatr 2000;89(8):921-5
   PubMed Web of Science ®Google Scholar
• Hoffman I, Tertychnyy A, Ectors N, Duodenogastro-esophageal reflux in children with refractory gastro-esophageal reflux disease. J Pediatr 2007;151(3):307-11
   PubMed Web of Science ®Google Scholar
• Bode S, Dreyer M, Greisen G. Gastric emptying and small intestinal transit time in preterm infants: a scintigraphic method. J Pediatr Gastroenterol Nutr 2004;39(4):378-82
   PubMed Web of Science ®Google Scholar
• Di Lorenzo C, Piepsz A, Ham H, Cadranel S. Gastric emptying with gastro-oesophageal reflux. Arch Dis Child 1987;62(5):449-53
   PubMed Web of Science ®Google Scholar
• Seibert JJ, Byrne WJ, Euler AR. Gastric emptying in children: unusual patterns detected by scintigraphy. AJR Am J Roentgenol 1983;141(1):49-51
   PubMed Web of Science ®Google Scholar
• Cucchiara S, Bortolotti M, Colombo C, Abnormalities of gastrointestinal motility in children with nonulcer dyspepsia and in children with gastroesophageal reflux disease. Dig Dis Sci 1991;36(8):1066-73
   PubMed Web of Science ®Google Scholar
• Miele E, Tozzi A, Staiano A, Persistence of abnormal gastrointestinal motility after operation for Hirschsprung's disease. Am J Gastroenterol 2000;95(5):1226-30
   PubMed Web of Science ®Google Scholar
• Yahav J, Avigad S, Frand M, Assessment of intestinal and cardiorespiratory function in children with congenital heart disease on high-caloric formulas. J Pediatr Gastroenterol Nutr 1985;4(5):778-85
   PubMed Web of Science ®Google Scholar
• Demirbilek S, Karaman A, Gurunluoglu K, Delayed gastric emptying in gastroesophageal reflux disease: the role of malrotation. Pediatr Surg Int 2005;21(6):423-7
   PubMed Web of Science ®Google Scholar
• Graff J, Brinch K, Madsen JL. Simplified scintigraphic methods for measuring gastrointestinal transit times. Clin Physiol 2000;20(4):262-6
   PubMedGoogle Scholar
• Bennink R, Peeters M, Van den Maegdenbergh V, Evaluation of small-bowel transit for solid and liquid test meal in healthy men and women. Eur J Nucl Med 1999;26(12):1560-6
   PubMedGoogle Scholar
• Mayer AP, Durward A, Turner C, Amylin is associated with delayed gastric emptying in critically ill children. Intensive Care Med 2002;28(3):336-40
   PubMed Web of Science ®Google Scholar
• Lodefalk M, Aman J, Bang P. Effects of fat supplementation on glycaemic response and gastric emptying in adolescents with type 1 diabetes. Diabet Med 2008;25(9):1030-5
   PubMed Web of Science ®Google Scholar
• Anderson BJ, van Lingen RA, Hansen TG, Acetaminophen developmental pharmacokinetics in premature neonates and infants: a pooled population analysis. Anesthesiology 2002;96(6):1336-45
   PubMed Web of Science ®Google Scholar
• Berseth CL, Ittmann PI. Antral and duodenal motor responses to duodenal feeding in preterm and term infants. J Pediatr Gastroenterol Nutr 1992;14(2):182-6
   PubMed Web of Science ®Google Scholar
• Ittmann PI, Amarnath R, Berseth CL. Maturation of antroduodenal motor activity in preterm and term infants. Dig Dis Sci 1992;37(1):14-19
   PubMed Web of Science ®Google Scholar
• Morriss FH Jr, Moore M, Weisbrodt NW, West MS. Ontogenic development of gastrointestinal motility: IV. Duodenal contractions in preterm infants. Pediatrics 1986;78(6):1106-13
   PubMed Web of Science ®Google Scholar
• Bisset WM, Watt JB, Rivers RP, Milla PJ. Measurement of small-intestinal motor activity in the preterm infant. J Biomed Eng 1988;10(2):155-8
   PubMedGoogle Scholar
• Berseth CL, Nordyke CK, Valdes MG, Responses of gastrointestinal peptides and motor activity to milk and water feedings in preterm and term infants. Pediatr Res 1992;31(6):587-90
   PubMedGoogle Scholar
• Al Tawil Y, Berseth CL. Gestational and postnatal maturation of duodenal motor responses to intragastric feeding. J Pediatr 1996;129(3):374-81
   PubMedGoogle Scholar
• Vajro P, Silano G, Longo D, Orocoecal transit time in healthy and constipated children. Acta Paediatr Scand 1988;77(4):583-6
   PubMedGoogle Scholar
• Van Den Driessche M, Van Malderen N, Geypens B, Lactose-[13C]ureide breath test: a new, noninvasive technique to determine orocecal transit time in children. J Pediatr Gastroenterol Nutr 2000;31(4):433-8
   PubMedGoogle Scholar
• Khin M, Bolin TD, Tin O, Investigation of small-intestinal transit time in normal and malnourished children. J Gastroenterol 1999;34(6):675-9
   PubMedGoogle Scholar
• Murphy MS, Nelson R, Eastham EJ. Measurement of small intestinal transit time in children. Acta Paediatr Scand 1988;77(6):802-6
   PubMedGoogle Scholar
• Vreugdenhil G, Sinaasappel M, Bouquet J. A comparative study of the mouth to caecum transit time in children and adults using a weight adapted lactulose dose. Acta Paediatr Scand 1986;75(3):483-8
   PubMedGoogle Scholar
• Geypens B, Bennink R, Peeters M, Validation of the lactose-[13C]ureide breath test for determination of orocecal transit time by scintigraphy. J Nucl Med 1999;40(9):1451-5
   PubMedGoogle Scholar
• Wutzke KD, Heine WE, Plath C, Evaluation of oro-coecal transit time: a comparison of the lactose-[13C, 15N]ureide 13CO2- and the lactulose H2-breath test in humans. Eur J Clin Nutr 1997;51(1):11-19
   PubMedGoogle Scholar
• Fallingborg J, Christensen LA, Ingeman-Nielsen M, Measurement of gastrointestinal pH and regional transit times in normal children. J Pediatr Gastroenterol Nutr 1990;11(2):211-14
   PubMed Web of Science ®Google Scholar
• Boehm G, Bierbach U, Senger H, Activities of lipase and trypsin in duodenal juice of infants small for gestational age. J Pediatr Gastroenterol Nutr 1991;12(3):324-7
   PubMedGoogle Scholar
• Jarvenpaa AL, Rassin DK, Kuitunen P, Feeding the low-birth-weight infant. III. Diet influences bile acid metabolism. Pediatrics 1983;72(5):677-83
   PubMedGoogle Scholar
• Challacombe DN, Edkins S, Brown GA. Duodenal bile acids in infancy. Arch Dis Child 1975;50(11):837-43
   PubMedGoogle Scholar
• Walkowiak J, Herzig KH, Strzykala K, Fecal elastase-1 is superior to fecal chymotrypsin in the assessment of pancreatic involvement in cystic fibrosis. Pediatrics 2002;110(1 Pt 1):e7
   PubMed Web of Science ®Google Scholar
• Nissler K, Von Katte I, Huebner A, Henker J. Pancreatic elastase 1 in feces of preterm and term infants. J Pediatr Gastroenterol Nutr 2001;33(1):28-31
   PubMed Web of Science ®Google Scholar
• de Winter BC, Monchaud C, Premaud A, Bayesian estimation of mycophenolate mofetil in lung transplantation, using a population pharmacokinetic model developed in kidney and lung transplant recipients. Clin Pharmacokinet 2012;51(1):29-39
   PubMed Web of Science ®Google Scholar
• Hines RN. The ontogeny of drug metabolism enzymes and implications for adverse drug events. Pharmacol Ther 2008;118(2):250-67
   PubMed Web of Science ®Google Scholar
• Stevens JC, Hines RN, Gu C, Developmental expression of the major human hepatic CYP3A enzymes. J Pharmacol Exp Ther 2003;307(2):573-82
   PubMed Web of Science ®Google Scholar
• Fakhoury M, Litalien C, Medard Y, Localization and mRNA expression of CYP3A and P-glycoprotein in human duodenum as a function of age. Drug Metab Dispos 2005;33(11):1603-7
   PubMed Web of Science ®Google Scholar
• Johnson TN, Tanner MS, Taylor CJ, Tucker GT. Enterocytic CYP3A4 in a paediatric population: developmental changes and the effect of coeliac disease and cystic fibrosis. Br J Clin Pharmacol 2001;51(5):451-60
   PubMed Web of Science ®Google Scholar
• Treluyer JM, Jacqz-Aigrain E, Alvarez F, Cresteil T. Expression of CYP2D6 in developing human liver. Eur J Biochem 1991;202(2):583-8
   PubMedGoogle Scholar
• Fukudo M, Yano I, Masuda S, Population pharmacokinetic and pharmacogenomic analysis of tacrolimus in pediatric living-donor liver transplant recipients. Clin Pharmacol Ther 2006;80(4):331-45
   PubMed Web of Science ®Google Scholar
• Fukudo M, Yano I, Yoshimura A, Impact of MDR1 and CYP3A5 on the oral clearance of tacrolimus and tacrolimus-related renal dysfunction in adult living-donor liver transplant patients. Pharmacogenet Genomics 2008;18(5):413-23
   PubMed Web of Science ®Google Scholar
• De Wildt SN, Kearns GL, Hop WC, Pharmacokinetics and metabolism of oral midazolam in preterm infants. Br J Clin Pharmacol 2002;53(4):390-2
   PubMedGoogle Scholar
• Paine MF, Shen DD, Kunze KL, First-pass metabolism of midazolam by the human intestine. Clin Pharmacol Ther 1996;60(1):14-24
   PubMed Web of Science ®Google Scholar
• Mandema JW, Tuk B, van Steveninck AL, Pharmacokinetic-pharmacodynamic modeling of the central nervous system effects of midazolam and its main metabolite alpha-hydroxymidazolam in healthy volunteers. Clin Pharmacol Ther 1992;51(6):715-28
   PubMedGoogle Scholar
• Blake MJ, Abdel-Rahman SM, Pearce RE, Effect of diet on the development of drug metabolism by cytochrome P-450 enzymes in healthy infants. Pediatr Res 2006;60(6):717-23
   PubMedGoogle Scholar
• Dietrich CG, Geier A, Oude Elferink RP. ABC of oral bioavailability: transporters as gatekeepers in the gut. Gut 2003;52(12):1788-95
   PubMed Web of Science ®Google Scholar
• Cascorbi I. P-glycoprotein: tissue distribution, substrates, and functional consequences of genetic variations. Handb Exp Pharmacol 2011;201:261-83
   PubMedGoogle Scholar
• Fanta S, Niemi M, Jonsson S, Pharmacogenetics of cyclosporine in children suggests an age-dependent influence of ABCB1 polymorphisms. Pharmacogenet Genomics 2008;18(2):77-90
   PubMed Web of Science ®Google Scholar
• Fakhoury M, Lecordier J, Medard Y, Impact of inflammation on the duodenal mRNA expression of CYP3A and P-glycoprotein in children with Crohn's disease. Inflamm Bowel Dis 2006;12(8):745-9
   PubMed Web of Science ®Google Scholar
• Zhao W, Fakhoury M, Deschenes G, Population pharmacokinetics and pharmacogenetics of mycophenolic acid following administration of mycophenolate mofetil in de novo pediatric renal-transplant patients. J Clin Pharmacol 2010;50(11):1280-91
   PubMed Web of Science ®Google Scholar
• Ohmann EL, Burckart GJ, Brooks MM, Genetic polymorphisms influence mycophenolate mofetil-related adverse events in pediatric heart transplant patients. J Heart Lung Transplant 2010;29(5):509-16
   PubMed Web of Science ®Google Scholar
• Zhao W, Elie V, Roussey G, Population pharmacokinetics and pharmacogenetics of tacrolimus in de novo pediatric kidney transplant recipients. Clin Pharmacol Ther 2009;86(6):609-18
   PubMed Web of Science ®Google Scholar
• Blanquet S, Zeijdner E, Beyssac E, A dynamic artificial gastrointestinal system for studying the behavior of orally administered drug dosage forms under various physiological conditions. Pharm Res 2004;21(4):585-91
   PubMed Web of Science ®Google Scholar
• Brouwers J, Anneveld B, Goudappel GJ, Food-dependent disintegration of immediate release fosamprenavir tablets: in vitro evaluation using magnetic resonance imaging and a dynamic gastrointestinal system. Eur J Pharm Biopharm 2011;77(2):313-19
   PubMedGoogle Scholar
• Wilding IR, Kenyon CJ, Hooper G. Gastrointestinal spread of oral prolonged-release mesalazine microgranules (Pentasa) dosed as either tablets or sachet. Aliment Pharmacol Ther 2000;14(2):163-9
   PubMed Web of Science ®Google Scholar
• Hines RN. Ontogeny of human hepatic cytochromes P450. J Biochem Mol Toxicol 2007;21(4):169-75
   PubMed Web of Science ®Google Scholar
• Johnson TN, Rostami-Hodjegan A, Tucker GT. Prediction of the clearance of eleven drugs and associated variability in neonates, infants and children. Clin Pharmacokinet 2006;45(9):931-56
   PubMed Web of Science ®Google Scholar
• Ince I, de Wildt SN, Tibboel D, Tailor-made drug treatment for children: creation of an infrastructure for data-sharing and population PK-PD modeling. Drug Discov Today 2009;14(5-6):316-20
   PubMed Web of Science ®Google Scholar
• de Wildt SN, Ito S, Koren G. Challenges for drug studies in children: CYP3A phenotyping as example. Drug Discov Today 2009;14(1-2):6-15
   PubMedGoogle Scholar
• Gorski JC, Jones DR, Haehner-Daniels BD, The contribution of intestinal and hepatic CYP3A to the interaction between midazolam and clarithromycin. Clin Pharmacol Ther 1998;64(2):133-43
   PubMed Web of Science ®Google Scholar
• Lappin G, Shishikura Y, Jochemsen R, Comparative pharmacokinetics between a microdose and therapeutic dose for clarithromycin, sumatriptan, propafenone, paracetamol (acetaminophen), and phenobarbital in human volunteers. Eur J Pharm Sci 2011;43(3):141-50
   PubMed Web of Science ®Google Scholar
• Lappin G, Garner RC. The utility of microdosing over the past 5 years. Expert Opin Drug Metab Toxicol 2008;4(12):1499-506
   PubMed Web of Science ®Google Scholar
• Lappin G, Kuhnz W, Jochemsen R, Use of microdosing to predict pharmacokinetics at the therapeutic dose: experience with 5 drugs. Clin Pharmacol Ther 2006;80(3):203-15
   PubMed Web of Science ®Google Scholar
• Baillie R, Gordi T, Vuong L, Evaluation of Ursodiol Pharmacokinetics in Neonates Using AMS, 2011; Available from: http://www.rosaandco.com/posters/rosaVitaleaASCPTposter2011.pdf. February 2012
   Google Scholar