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Therapeutic potential of green tea: a new horizon in drug discovery

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Pages 349-359 | Published online: 20 Mar 2007

Bibliography

  • WHO policy perspectives on medicines: Traditional medicine – growing needs and potential. WHO, Geneva, Switzerland (2002) 2:1-6.
  • EISENBERG DM, KESSELER RC, FOSTER C et al.: Unconventional medicine in the United States. Prevalence, costs and patterns of use. N. Engl. J. Med. (1993) 328:246-252.
  • MUKHTAR H, AHMAD N: Green tea in chemoprevention of cancer. Toxicol. Sci. (1999) 52(S):111-117.
  • YANG TTC, KOO MWL: Hypocholesterolemic effects of Chinese tea. Pharmacol. Res. (1997) 35(6):505-512.
  • GRAHAM HN: Green tea composition, consumption and polyphenol chemistry. Prev. Med. (1992) 21:334-350.
  • BALANTINE DA, WISEMAN SA, BOUWENS LC: The chemistry of tea flavonoids. Crit. Rev. Food Sci. Nutr. (1997) 37:693-704.
  • CABRERA C, ARTACHO R, GIMENEZ R: Beneficial effects of green tea-a review. J. Am. Coll. Nutr. (2006) 25(2):79-99.
  • MUKHTAR H, AHMAD N: Tea polyphenols: prevention of cancer and optimizing health. Am. J. Clin. Nutr. (2000) 71(S):1698S-1702S.
  • YU R, JIAO JJ, DUH JL: Activation of mitogen-activated protein kinases by green tea polyphenolic potential signaling pathways in the regulation of antioxidant-responsive element-modified phase II enzyme gene expression. Carcinogenesis (1997) 18:451-456.
  • JANKUN J, SELMAN SH, SWIERCZ R, SKRZYPEZAK-JANKUN E: Why drinking green tea could prevent cancer. Nature (1997) 387:561.
  • AHMAD N, FYES DK, NIEMINEN AL et al.: Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells. J. Natl. Cancer Inst. (1997) 89:1881-1886.
  • LIANG YC, LIN-SHIAN SY, CHEN CF, LIN JK: Supression of extracellular signals and cell proliferation through EGF receptor binding bu (-)-epigallocatechin gallate in human A431 epidermoid carcinoma cells. J. Cell. Biochem. (1997) 67:55-65.
  • LIN YL, LIN JK: (-)-Epigallocatechin-3-gallate blocks the induction of nitric oxide synthase by down-regulating lipopolysaccharide induced activity of transcription factor nuclear factor-kappa. B. Mol. Pharmacol. (1997) 52:465-472.
  • DONG Z, MA WY, HUANG C, YANG CS: Inhibition of tumor promoter induced activator protein 1 activation and cell transformation by tea polyphenols, (-)-epigallocatechin gallate and theaflavins. Cancer. Res. (1997) 57:4414-4419.
  • IMAI K, SUGA K, NAKACHI K: Cancer preventive effects of drinking tea among a Japanese population. Prev. Med. (1997) 26:769-775.
  • KELLOFF GJ, CROWELL JA, STEELE VE et al.: Progress in cancer chemoprevention: development of diet-derived chemopreventive agents. J. Nutr. (2000) 130(S):467-471.
  • LIANG YC, LIN-SHIAN SY, CHEN CF, LIN JK: Inhibition of cyclin-dependent kinase 2 and 4 activities as well as induction of cdk inhibitors p21 and p27 during growth arrest of human breast carcinoma cells by (-)-epigallocatechin-3-gallate. J. Cell. Biochem. (1999) 75:1-12.
  • VALCIC S, TIMMERMANN BN, ALBERTS DS et al.: Inhibitory effect of six green tea catechins and caffeine on growth of four selected human tumor cell lines. Anti-Cancer Drugs (1996) 7:461-468.
  • LIN JK, LIANG YC, LIN-SHIAU SY: Cancer chemoprevention by tea polyphenols through mitotic signal transduction blockade. Biochem. Pharmacol. (1999) 58:911-915.
  • FUIJIKI H, SUGANUMA M, OKABE S et al.: Mechanistic findings of green tea as cancer preventive for humans. Proc. Soc. Exp. Biol. Med. (1999) 220:225-228.
  • NIHAL A, HASAN M: Green tea polyphenols and cancer: biological mechanisms and practical implications. Nutr. Rev. (1999) 57:78-83.
  • BERGER SJ, GUPTA S, BELFI CA, GOSKY DM, MUKHTAR H: Green tea constituent (-)-epigallocatechin-3-gallate inhibits topoisomerase I activity in human colon carcinoma cells. Biochem. Biophys. Res. Commun. (2001) 288:101-105.
  • AHMED N, GUPTA S, MUKHTAR H: Green tea polyphenol epigallocatechin-3-gallate differentially modulates nuclear factor kappa B in cancer cells versus normal cells. Arch. Biochem. Biophys. (2000) 376:338-346.
  • GABRISA S, SARTOR L, BIGGIN S, SALVATO B, BENELLI R, ALBINI A: Tumor gelatinases and invasion inhibited by the green tea flavanol epigallocatechin-3-gallate. Cancer (2001) 91:822-832.
  • JUNG YD, KIM MS, SHIN BA et al.: EGCG, a mjor component of green tea inhibits tumor growth by inhibiting VEGF induction in human colon carcinoma cells. Br. J. Cancer (2001) 84:844-850.
  • ARAB L, LL’YASOVA: The epidemiology of tea consumption and colorectal cancer incidence. J. Nutr. (2003) 133:3310S-3318S.
  • LI N, SUN Z, HAN C, CHEN J: The chemopreventive effects of tea on human oral precancerous mucosa lesions. Proc. Soc. Exp. Biol. Med. (1999) 220:218-224.
  • KHAN SG, KATIYAR SK, AGARWAL R, MUKHTAR H: Enhancement of antioxidant and phase II enzymes by oral feeding of green tea polyphenols in drinking water to SKH-I hairless mice: possible role in cancer chemoprevention. Cancer Res. (1992) 52:4050-4052.
  • HIDER RC, LIU ZD, KHODR HH: Metal chelation of polyphenols. Methods Enzymol. (2001) 35:190-203.
  • FREI B, HIGDON JV: Antioxidant activity of tea polyhenols in vivo: evidence from animal. J. Nutr. (2003) 133:3275S-3284S.
  • DONOVAN JL, DEVANE CL, CHAVIN KD et al.: Oral administration of a decaffeinated green tea (Camellia sinensis) extract did not alter urinary 8-epi-prostaglandin F(2α), a biomarker for in-vivo lipid peroxidation. J. Pharm. Pharmacol. (2005) 57(10):1365-1369.
  • COIMBRA S, CASTRO E, ROCHA-PEREIRA P, REBELO I, ROCHA S, SANTOS-SILVA A: The effect of green tea in oxidative stress. Clin. Nutr. (2006) 25(5):790-796.
  • GUPTA SK, HALDER N, SRIVASTAVA S, TRIVEDI D, JOSHI S, VERMA SD: Green tea protects against selenite-induced oxidative stress in experimental cataractogenesis. Ophthalmic Res. (2002) 34:258-263.
  • VINSON JA, ZHANG J: Black and green teas equally inhibit diabetic cataracts in streptozotocin- induced rat model of diabetes. J. Agric. Food Chem. (2005) 53:3710-3713.
  • THIAGARAJAN G, CHANDANI S, SUNDARI CS, RAO SH, KULKARNI AV, BALASUBRAMANIAN D: Antioxidant properties of green and black tea, and their potential ability to retard the progression of eye lens cataract. Exp. Eye Res. (2001) 73(3):393-401.
  • ZHANG B, OSBORNE NN: Oxidative-induced retinal degeneration is attenuated by epigallocatechin gallate. Brain Res. (2006) 1124(1):176-187.
  • NIE G, CAO Y, ZHAO B: Preventive effects of green tea polyphenols and their major component, (-)-epigallocatechin-3-gallate (EGCG), on hydroxydopamine-induced apoptosis in PC12 cells. Redox Rep. (2002) 7(3):171-177.
  • LUO H, TANG L, TANG M et al.: Phase IIa chemoprevention trial of green tea polyphenols in high risk individuals of liver cancer: modulation of urinary excretion of green tea polyphenols and 8-hydroxydeoxyguanosine. Carcinogenesis (2006) 27(2):262-268.
  • UNNO K, TAKABAYASHI F, YOSHIDA H et al.: Daily consumption of green tea catechins delays memory regression in aged mice. Biogerontology (2006) Epub ahead of print.
  • SKRZYDLEWSKA E, AUGUSTYNIAK A, MICHALAK K, FARBISZEWSKI R: Green tea supplementation in rats of different ages mitigates ethanol-induced changes in brain antioxidant abilities. Alcohol (2005) 37(2):89-98.
  • KAKUDA T, YANASE H, UTSUNOMIYA K, NOZAWA A, UNNO T, KATAOKA K: Protective effect of γ-glutamylethylamide (theanine) on ischemic delayed neuronal death in gerbils. Neurosci. Lett. (2000) 289(3):189-192.
  • SHINICHI K, ATSUSHI H, KAORI O et al.: Green tea consumption and cognitive function: a cross sectional study from the Tsurugaya Project. Am J. Clin. Nutr. (2006) 83(2):355-361.
  • KONO S, SHINCHI K, IKEDA N: Green tea consumption and serum lipid profiles: a cross sectional study in Northern Kyushu, Japan. Prev. Med. (1992) 21:526-531.
  • CHAN PT, FONG WP, CHEUNG YL: Jasmine green tea epicatechins are hypolipidemic in hamsters (Mesocricetus auratus) fed a high fat diet. J. Nutr. (1999) 129:1094-1101.
  • BURSILL CA, ABBEY M, ROACH PD: A green tea extract lowers plasma cholesterol by inhibiting cholesterol synthesis and upregulating the LDL receptor in the cholesterol-fed rabbit. Atherosclerosis (2006) Epub ahead of print.
  • BABU PV, SABITHA KE, SHYAMALADEVI CS: Therapeutic effect of green tea extract on oxidative stress in aorta and heart of streptozotocin diabetic rats. Chem. Biol. Interact. (2006) 162(2):114-120.
  • BABU PV, SABITHA KE, SHYAMALADEVI CS: Green tea impedes dyslipidemia, lipid peroxidation, protein glycation and ameliorates Ca2+-ATPase and Na+/K+-ATPase activity in the heart of streptozotocin-diabetic rats. Chem. Biol. Interact. (2006) 162(2):157-164.
  • YOKOZAWA T, NAKAGAWA T, OYA T, OKUBO T, JUNEJA LR: Green tea polyphenols and dietary fibre protect against kidney damage in rats with diabetic nephropathy. J. Pharm. Pharmacol. (2005) 57(6):773-780.
  • ZHONG L, FURNE JK, LEVITT MD: An extract of black, green and mulberry teas causes malabsorption of carbohydrates but not of triacylglycerol in healthy volunteers. Am. J. Clin. Nutr. (2006) 84(3):551-555.
  • SHIMIZU M: Modulation of intestinal function by food substances. Nahrung (1999) 43:154-158.
  • JUHEL C, ARMAND M, PAFUMI Y, ROSIER C, VANDERMANDER J, LAIRON D: Green tea extract (AR25) inhibits lipolysis of triglycerides in gastric and duodenal medium in vitro. J. Nutr. Biochem. (2000) 11:45-51.
  • IKEDA I, IMASATO Y, SASAKI E et al.: Tea catechins decrease micellar solubility and intestinal malabsorption of cholesterol in rats. Biochem. Biophys. Acta. (1992) 1127:141-146.
  • BURSILL C, ROACH PD, BOTTEMA CD, PAL S: Green tea upregulates the low-density lipoprotein receptors through the sterol-regulated element binding protein in HepG2 liver cells. J. Agric. Food Chem. (2001) 49:5639-5645.
  • KUHN DJ, BURNS AC, KAZIN A, PING-DOU Q: Direct inhibition of the ubiquitin-proteasome pathway by ester bond-containing green tea polyphenols is associated with increased expression of sterol regulatory element-binding protein 2 and LDL receptor. Biochem. Biophys. Acta. (2004) 1682:1-10.
  • PERSSON IA, JOSEFSSON M, PERSSON K, ANDERSSON RG: Tea flavanols inhibit angiotensin-converting enzyme activity and increase nitric oxide production in human endothelial cells. J. Pharm. Pharmacol. (2006) 58(8):1139-1144.
  • STEPHANOU A: Role of STAT-1 and STAT-3 in ischemia/reperfusion injury. J. Cell. Mol. Med. (2004) 8:519-525.
  • SOHN OS, SURACE A, FIALA ES et al.: Effects of green and black tea on hepatic xenobiotic metabolizing systems in the male rats. Xenobiotica (1994) 24:119-127.
  • MUTO S, FUJITA KI, YAMAZAKI Y, KAMATAKI B: Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450. Mutat. Res. (2001) 479:197-206.
  • YANG CS, WANG Z: Tea and cancer review. J. Natl. Cancer. Inst. (1993) 85:1038-1049.
  • AFZAL M, SAFER AM, AL-BLOUSHI S: CoQ9 potentiates green tea antioxidant activities in Wistar rats. Biofactors (2005) 25(1-4):255-259.
  • JEONG BC, KIM BS, KIM JI, KIM HH: Effects of green tea on urinary stone formation: an in vivo and in vitro study. J. Endourol. (2006) 20(5):356-361.
  • ITOH Y, YASUI T, OKADA A, TOZAWA K, HAYASHI Y, KOHR K: Preventive effect of green tea on renal stone formation and the role of oxidative stress in nephrolithiasis. J. Urol. (2005) 173(1):271-275.
  • MOHAMADIN AM, EL-BESHBISHY HA, EL-MAHDY MA: Green tea extract attenuates cyclosporine A-induced oxidative stress in rats. Pharmacol. Res. (2005) 51(1):51-57.
  • YOKOZAWA T, CHO EJ, NAKAGAWA T: Influence of green tea polyphenols in rats with arginine-induced renal failure. J. Agric. Food Chem. (2003) 51(8):2421-2425.
  • ISBRUCKER RA, EDWARDS JA, WOLZ E, DAVIDOVICH A, BAUSCH J: Safety studies on epigallocatechin gallate (EGCG) preparations. Part 3: teratogenicity and reproductive toxicity studies in rats. Food Chem. Toxicol. (2006) 44(5):651-661.
  • WESTPHAL LM, POLAN ML, TRANT AS, MOONEY SB: A nutritional supplement for improving fertility in women: a pilot study. J. Reprod Med. (2004) 49(4):289-293.
  • GUTMAN RI, RYU BH: Rediscovering tea. An explanation of the scientific literature. HerbalGram (1996) 37:33-48.
  • SAKANAKA S, SATO T, KIM M, YAMAMOTO T: Inhibitory effects of green tea polyphenols on glucan synthesis and cellular adherence of cariogenic streptococci. Agric. Biol. Chem. (1990) 54:2925-2929.
  • SAKANAKA S, AIZAWA M, KIM M, YAMAMOTO T: Inhibitory effects of green tea polyphenols on growth and cellular adherence of an oral bacterium, Porphyromonas gingivalis. Biosci. Biotechnol. Biochem. (1996) 60:745-749.
  • ZHANG J, KASHKET S: Inhibition of salivary amylase by black and green teas and their effects on the intraoral hydrolysis of starch. Caries Res. (1998) 32:233.
  • UI M: The effect of tea catechins for halitosis. Proc. Intern. Symp. Tea Sci. (1991):332-336.
  • WEISBURGER JH: Tea and health: the underlying mechanisms. Proc. Soc. Exp. Biol. Med. (1999) 220:271-275.
  • YAMAMOTO T, JUNEJA LR, CHU DC, KIM M: Chemistry and applications of green tea. CRC Press LLC, Boca Raton, USA (1997).
  • HENDEL J, NIELSEN OH: Expression of cycloxygenase-2 mRNA in active inflammatory bowel disease. Am. J. Gastroenterol. (1997) 92:1170-1173.
  • SAFAR S, ABDEEN S, DASHTI H et al.: Effect of green tea in the prevention and reversal of fasting-induced intestinal mucosal damage. Nutrition (2003) 19(6):536-540.
  • YEE YK, KOO MWL, SZETO M: Helicobacter pylori infection: risk and virulence. Chinese tea consumption and lower risk of Helicobacter infection. J. Gastroenterol. Hepatol. (2002) 17:552-555.
  • MATSUBARA S, SHIBATA H, ISHIKAWA F et al.: Suppression of Helicobacter pylori-induced gastritis by green tea extract in Mongolian gerbils. Biochem. Biophys. Res. Commun. (2003) 310:715-719.
  • SETIAWAN VW, ZHANG ZF, YU GP et al.: Protective effect of green tea on the risk of chronic gastritis and stomach cancer. Int. J. Cancer (2001) 92:600-604.
  • NAKAGAWA K, OKUDA S, MIYZJAWA T: Dose-dependent incorporation of tea catechins (-)-epigallocatechin-3-gallate and (-)-epigallocatechin, into human plasma. Biosci. Biotechnol. Biochem. (1997) 61:1981-1985.
  • PISKULA MK TERAO J: Accumulation of (-)-epicatechin metabolites in rat plasma after oral administration and distribution of conjugation enzymes in rat tissues. J. Nutr. (1998) 128:1172-1178.
  • AURA A, O’LEARY KA, WILLIAMSON G et al.: Quercetin derivatives are deconjugated and converted to hydroxyphenylacetic acids but not methylated by human fecal flora in vitro. J. Agric. Food Chem. (2002) 50:1725-1730.
  • LI C, LEE MJ, SHENG S et al.: Structural identification of two metabolites of catechins and their kinetics in human urine and blood after tea consumption. Chem. Res. Toxicol. (2000) 13:177-184.
  • MESELHY MR, NAKAMURA N, HATTORI M: Biotransformation of (-)-epicatechin-3-O-gallate by human intestinal bacteria. Appl. Environ. Microbiol. (1989) 55:1203-1208.
  • NAKAGAWA K, MIYZJAWA T: Absorption and distribution of tea catechins, (-)-epigallocatechin-3-gallate in the rat. J. Nutr. Sci. Vitaminol. (1997) 43:679-684.
  • LAMBERT JD, YANG CS: Cancer chemopreventive activity and bioavailability of tea and tea polyphenols. Mutat. Res. (2003) 523-524:201-208.
  • SUGANUMA M, OKABE S, ONIYAMA M, TADA Y, ITO H, FUJIKI H: Wide distribution of [3H] (-) epigallocatechin gallate, a cancer preventive tea polyphenol, in mouse tissue. Carcinogenesis (1998) 19(10):1770-1776.
  • HE YH, KIES C: Green and black tea consumption by humans: impact on polyphenol concentrations in feces, blood and urine. Plant Foods Hum. Nutr. (1994) 46:221-229.
  • KROON PA, CLIFFORD MN, CROZIER A et al.: How should we assess the effects of exposure to dietary polyphenols in vitro? Am. J.Clin. Nutr. (2004) 80:15-21.

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