Cytokines: monitors of disease severity for the clinic

Bibliography

• Biomarkers Definitions Working Group. Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clin Pharmacol Ther 2001;69:89-95
   PubMed Web of Science ®Google Scholar
• Illei GG, Tackey E, Lapteva L, Lipsky PE. Biomarkers in systemic lupus erythematosus. Arthritis Rheum 2004;50:1709-20
   PubMed Web of Science ®Google Scholar
• Suh CH, Kim HA. Cytokines and their receptors as biomarkers of systemic lupus erythematosus. Expert Rev Mol Diagn 2008;8:189-98
   PubMed Web of Science ®Google Scholar
• Grewal IS. CD70 as a therapeutic target in human malignancies. Expert Opin Ther Targets 2008;12:341-51
   PubMed Web of Science ®Google Scholar
• Prasad AS, Fitzgerald JT, Bao B, et al. Duration of symptoms and plasma cytokine levels in patients with the common cold treated with zinc acetate. A randomized, double-blind, placebo-controlled trial. Ann Intern Med 2000;133:245-52
   PubMed Web of Science ®Google Scholar
• Hartsell WF, Scott CB, Dundas GS, et al. Can serum markers be used to predict acute and late toxicity in patients with lung cancer? Analysis of RTOG 91-03. Am J Clin Oncol 2007;30:368-76
   PubMed Web of Science ®Google Scholar
• Feigin A. Evidence from biomarkers and surrogate endpoints. NeuroRx 2004;1:323-30
   PubMedGoogle Scholar
• Pepe MS, Etzioni R, Feng Z, et al. Phases of biomarker development for early detection of cancer. JNCI 2001;93:1054-61
   PubMed Web of Science ®Google Scholar
• Baker SG, Kramer BS, McIntosh M, et al. Evaluating markers for the early detection of cancer: overview of study designs and methods. Clin Trials 2006;3:43-56
   PubMed Web of Science ®Google Scholar
• Packard R, Libby P. Inflammation in atherosclerosis: from vascular biology to biomarker discovery and risk prediction. Clin Chem 2008;54:24
   PubMed Web of Science ®Google Scholar
• Schwab C, McGeer PI. Inflammatory aspects of Alzheimer's Disease and other neurodegenerative disorders. J Alzheimers Dis 2008;13:359-69
   PubMed Web of Science ®Google Scholar
• Vojdani A. Antibodies as predictors of autoimmune diseases and cancer. Exp Opin Med Diagn 2008;2:593-606
   PubMedGoogle Scholar
• Burkly LC, Michaelson JS, Hahm K, et al. TWEAKing tissue remodeling by a multifunctional cytokine: role of TWEAK/Fn14 pathway in health and disease. Cytokine 2007;40:1-16
   PubMed Web of Science ®Google Scholar
• Clynes R, Moser B, Yan SF, et al. Receptor for AGE (RAGE): weaving tangled webs within the inflammatory response. Curr Mol Med 2007;7:743-51
   PubMed Web of Science ®Google Scholar
• Aujla SJ, Dubin PJ, Kolls JK. Interleukin-17 in pulmonary host defense. Exp Lung Res 2007;33:507-18
   PubMed Web of Science ®Google Scholar
• Collison LW, Workman CJ, Kuo TT, et al. The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature 2007;45:566-9
   Google Scholar
• Holm TL, Nielsen J, Claesson MH. CD4+CD25+ regulatory T cells: I Phenotype and physiology. APMIS 2004;112:629-41
   PubMed Web of Science ®Google Scholar
• Calvani N, Richards HB, Tucci M, et al. Up-regulation of IL-18 and predominance of a Th1 immune response is a hallmark of lupus nephritis. Clin Exp Immunol 2004;138:171-8
   PubMed Web of Science ®Google Scholar
• Aujla SJ, Chan YR, Zheng M, et al. IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia. Nat Med 2008;14:247-9
   PubMed Web of Science ®Google Scholar
• Hiscock N, Stanley Chan MH, Bisucci T, et al. Skeletal myocytes are a source of interleukin-6 mRNA expression and protein release during contraction: evidence of fiber type specificity. FASEB 2004;4:992-4
   Google Scholar
• Blumberg H, Conklin D, Xu WF, et al. Interleukin 20: Discovery, receptor identification, and role in epidermal function. Cell 2001;104:9-19
   PubMed Web of Science ®Google Scholar
• LaPorte SL, Juo ZS, Vaclavikova J, et al. Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system. Cell 2008;132:259-72
   PubMed Web of Science ®Google Scholar
• Spolski R, Leonard WJ. Interleukin-21: basic biology and implications for cancer and autoimmunity. Annu Rev Immunol 2008;26:57-79
   PubMed Web of Science ®Google Scholar
• Vermijlen D, Ellis P, Langford C, et al. Distinct cytokine-driven responses of activated blood gammadelta T cells: insights into unconventional T cell pleiotropy. J Immunol 2007;178:4304-14
   PubMed Web of Science ®Google Scholar
• Borish LC, Steinke JW. Cytokines and chemokines. J Allergy Clin Immunol 2003;111:S460-75
   PubMedGoogle Scholar
• Available from: http://www.copewithcytokines.de/cope.cgi.
   Google Scholar
• Zlotnik A, Yoshie O. Chemokines: a new classification system and their role in immunity. Immunity 2000;12:121-7
   PubMed Web of Science ®Google Scholar
• Kofoed K, Schneider UV, Scheel T, et al. Development and validation of a multiplex add-on assay for sepsis biomarkers using xMAP technology. Clin Chem 2006;52:1284-93
   PubMed Web of Science ®Google Scholar
• Ryu OH, Atkinson JC, Hoehn GT, et al. Identification of parotid salivary biomarkers in Sjogren's syndrome by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry and two-dimensional difference gel electrophoresis. Rheumatology 2006;45:1077-86
   PubMed Web of Science ®Google Scholar
• Bauskin AR, Brown DA, Kuffner T, et al. Role of macrophage inhibitory cytokine-1 in tumorigenesis and diagnosis of cancer. Cancer Res 2006;66:4983-6
   PubMed Web of Science ®Google Scholar
• Yang H, Filipovic Z, Brown D, et al. Macrophage inhibitory cytokine-1: a novel biomarker for p53 pathway activation. Mol Cancer Ther 2003;2:1023-9
   PubMed Web of Science ®Google Scholar
• Mignot G, Ullrich E, Bonmort M, et al. The critical role of IL-15 in the antitumor effects mediated by the combination therapy imatinib and IL-2. J Immunol 2008;18:6477-83
   Google Scholar
• Kryczek I, Wei S, Zou L, et al. Cutting edge: Th17 and regulatory T cell dynamics and the regulation by IL-2 in the tumor microenvironment. J Immunol 2007;178:6730-3
   PubMed Web of Science ®Google Scholar
• Fichtner-Feigl S, Terabe M, Kitani A, et al. Restoration of tumor immunosurveillance via targeting of interleukin-13 receptor-alpha 2. Cancer Res 2008;68:3467-75
   PubMed Web of Science ®Google Scholar
• Chechlinska M, Kowalska M, Kaminska J. Cytokines as potential tumour markers. Exp Opin Med Diagn 2008;2:691-711
   PubMedGoogle Scholar
• Atanackovic D, Cao Y, Kim JW, et al. The local cytokine and chemokine milieu within malignant effusions. Tumour Biol 2008;29:93-104
   PubMed Web of Science ®Google Scholar
• Zlotnik A. New insights on the role of CXCR4 in cancer metastasis. J Pathol 2008;215:211-3
   PubMed Web of Science ®Google Scholar
• Burger JA, Kipps TJ. CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment. Blood 2006;107:1761-7
   PubMed Web of Science ®Google Scholar
• Ruffini PA, Morandi P, Cabioglu N, et al. Manipulating the chemokine-chemokine receptor network to treat cancer. Cancer 2007;109:2392-404
   PubMed Web of Science ®Google Scholar
• Smith JR, Braziel RM, Paoletti S, et al. Expression of B-cell-attracting chemokine 1 (CXCL13) by malignant lymphocytes and vascular endothelium in primary central nervous system lymphoma. Blood 2003;10:815-21
   Google Scholar
• Lacour S, Gautier JC, Pallardy M, Roberts R. Cytokines as potential biomarkers of liver toxicity. Cancer Biomark 2005;1:29-39
   PubMedGoogle Scholar
• Gaïni S, Pedersen SS, Koldkaer OG, et al. New immunological serum markers in bacteraemia: anti-inflammatory soluble CD163, but not proinflammatory high mobility group-box 1 protein, is related to prognosis. Clin Exp Immunol 2008;151:423-31
   PubMed Web of Science ®Google Scholar
• Gaïni S, Koldkjaer OG, Møller HJ, et al. A comparison of high-mobility group-box 1 protein, lipopolysaccharide-binding protein and procalcitonin in severe community-acquired infections and bacteraemia: a prospective study. Crit Care 2007;11:R76
   PubMed Web of Science ®Google Scholar
• Balci C, Sungurtekin H, Gurses E, et al. Usefulness of procalcitonin for diagnosis of sepsis in the intensive care unit. Crit Care 2003;7:85-90
   PubMed Web of Science ®Google Scholar
• Houben EN, Nguyen L, Pieters J. Interaction of pathogenic mycobacteria with the host immune system. Curr Opin Microbiol 2006;9:76-85
   PubMed Web of Science ®Google Scholar
• Küpeli E, Karnak D, Beder S, et al. Diagnostic accuracy of cytokine levels (TNF-alpha, IL-2 and IFN-gamma) in bronchoalveolar lavage fluid of smear-negative pulmonary tuberculosis patients. Respiration 2008;75:73-8
   PubMed Web of Science ®Google Scholar
• Ribeiro-Rodrigues R, Resende Co T, Johnson JL, et al. Sputum cytokine levels in patients with pulmonary tuberculosis as early markers of mycobacterial clearance. Clin Diagn Lab Immunol 2002;9:818-23
   PubMedGoogle Scholar
• Barot-Ciorbaru R. Immunomodulation by bacterial fractions. Int J Immunopharmacol 1994;16:469-73
   PubMed Web of Science ®Google Scholar
• Detjen AK, Keil T, Roll S, et al. Interferon-gamma release assays improve the diagnosis of tuberculosis and nontuberculous mycobacterial disease in children in a country with low incidence of tuberculosis. Clin Infect Dis 2007;45:322-8
   PubMed Web of Science ®Google Scholar
• Janssens JP. Clinical utility of the interferon-{gamma} release assay for elderly patients with active tuberculosis: a word of caution. Chest 2008;134:471-2
   PubMedGoogle Scholar
• Nakae S, Iwakura Y, Suto H, Galli SJ. Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17. J Leukoc Biol 2007;8:1258-68
   Google Scholar
• Sirskyj D, Thèze J, Kumar A, Kryworuchko M. Disruption of the gamma c cytokine network in T cells during HIV infection. Cytokine 2008;43:1-14
   PubMed Web of Science ®Google Scholar
• Torre D, Pugliese A. Interleukin-18: a proinflammatory cytokine in HIV-1 infection. Curr HIV Res 2006;4:423-30
   PubMed Web of Science ®Google Scholar
• Bourgarit A, Carcelain G, Martinez V, et al. Explosion of tuberculin-specific Th1-responses induces immune restoration syndrome in tuberculosis and HIV co-infected patients. AIDS 2006;20:F1-7
   PubMed Web of Science ®Google Scholar
• Herbein G, Khan KA. Is HIV infection a TNF receptor signaling-driven disease? Trends Immunol 2008;29:61-7
   PubMed Web of Science ®Google Scholar
• Leong AS, Wong KT, Leong TY, et al. The pathology of dengue hemorrhagic fever. Semin Diagn Pathol 2007;24:227-36
   PubMed Web of Science ®Google Scholar
• Kurane I. Dengue hemorrhagic fever with special emphasis on immunopathogenesis. Comp Immunol Microbiol Infect Dis 2007;30:329-4
   PubMed Web of Science ®Google Scholar
• Pang T, Cardosa MJ, Guzman MG. Of cascades and perfect storms: the immunopathogenesis of dengue haemorrhagic fever-dengue shock syndrome (DHF/DSS). Immunol Cell Biol 2007;85:43-5
   PubMed Web of Science ®Google Scholar
• Bozza FA, Cruz OG, Zagne SM, et al. Multiplex cytokine profile from dengue patients: MIP-1beta and IFN-gamma as predictive factors for severity. BMC Infect Dis 2008;8:86
   PubMed Web of Science ®Google Scholar
• Lam CW, Chan MH, Wong CK. Severe acute respiratory syndrome: clinical and laboratory manifestations. Clin Biochem Rev 2004;25:121-32
   PubMedGoogle Scholar
• Huang KJ, Su IJ, Theron M, et al. An interferon-gamma-related cytokine storm in SARS patients. J Med Virol 2005;75:185-94
   PubMed Web of Science ®Google Scholar
• Chien JY, Hsueh PR, Cheng WC, et al. Temporal changes in cytokine/chemokine profiles and pulmonary involvement in severe acute respiratory syndrome. Respirology 2006;11:715-22
   PubMed Web of Science ®Google Scholar
• Jiang Y, Xu J, Zhou C, et al. Characterization of cytokine/chemokine profiles of severe acute respiratory syndrome. Am J Respirat Crit Care Med 2005;171:850-7
   PubMed Web of Science ®Google Scholar
• Ishihara K, Hirano T. IL-6 in autoimmune disease and chronic inflammatory proliferative disease. Cytokine Growth Factor Rev 2002;13:357-68
   PubMed Web of Science ®Google Scholar
• Kolls JK, Linden A. Interleukin-17 family members and inflammation. Immunity 2004;21:467-76
   PubMed Web of Science ®Google Scholar
• Matusevicius D, Kivisäkk P, He B, et al. Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis. Mult Scler 1999;5:101-4
   PubMed Web of Science ®Google Scholar
• Röhn TA, Jennings GT, Hernandez M, et al. Vaccination against IL-17 suppresses autoimmune arthritis and encephalomyelitis. Eur J Immunol 2006;36:2857-67
   PubMed Web of Science ®Google Scholar
• Haider AS, Lowes MA, Suárez-Fariñas M, et al. Identification of cellular pathways of ‘type 1,’ Th17 T cells, and TNF- and inducible nitric oxide synthase-producing dendritic cells in autoimmune inflammation through pharmacogenomic study of cyclosporine A in psoriasis. J Immunol 2008;180:1913-20
   PubMed Web of Science ®Google Scholar
• Zaba LC, Cardinale I, Gilleaudeau P, et al. Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses. J Exp Med 2007;204:3183-94
   PubMed Web of Science ®Google Scholar
• Zhang C, Zhang J, Yang B, Wu C. Cyclosporin A inhibits the production of IL-17 by memory Th17 cells from healthy individuals and patients with rheumatoid arthritis. Cytokine 2008;42:345-52
   PubMed Web of Science ®Google Scholar
• Zheng TS, Burkly LC. No end in site: TWEAK/Fn14 activation and autoimmunity associated- end-organ pathologies. J Leukoc Biol 2008;84:338-47
   PubMed Web of Science ®Google Scholar
• Kamijo S, Nakajima A, Kamata K, et al. Involvement of TWEAK/Fn14 interaction in the synovial inflammation of RA. Rheumatology 2008;47:442-50
   PubMed Web of Science ®Google Scholar
• Berner B, Akça D, Jung T, et al. Analysis of Th1 and Th2 cytokines expressing CD4+ and CD8+ T cells in rheumatoid arthritis by flow cytometry. J Rheumatol 2000;27:1128-35
   PubMed Web of Science ®Google Scholar
• Rosengren S, Firestein GS, Boyle DL. Measurement of Inflammatory Biomarkers in Synovial Tissue Extracts by Enzyme-Linked Immunosorbent Assay. Clin Diagn Lab Immunol 2003;10:1002-10
   PubMedGoogle Scholar
• Nakamura RM. Progress in the use of biochemical and biological markers for evaluation of rheumatoid arthritis. J Clin Lab Anal 2000;14:305-313
   PubMed Web of Science ®Google Scholar
• Horwood N. Lymphocyte-derived cytokines in inflammatory arthritis. Autoimmunity 2008;41:230-8
   PubMed Web of Science ®Google Scholar
• Wollheim FA. Markers of Disease in Rheumatoid arthritis. Curr Opin Rheumatol 2000;12:200-4
   PubMed Web of Science ®Google Scholar
• Liu CC, Manzi S, Ahearn JM. Biomarkers for systemic lupus erythematosus: a review and perspective. Curr Opin Rheumatol 2005;17:543-9
   PubMed Web of Science ®Google Scholar
• Chun HY, Chung JW, Kim HA, et al. Cytokine IL-6 and IL-10 as biomarkers in systemic lupus erythematosus. J Clin Immunol 2007;27:461-6
   PubMed Web of Science ®Google Scholar
• Aringer M, Smolen S. Tumour necrosis factor and other proinflammatory cytokines in systemic lupus erythematosus: a rationale for therapeutic intervention. Lupus 2004;13:344-7
   PubMed Web of Science ®Google Scholar
• Park MC, Park YB, Lee SK. Elevated interleukin-18 levels correlated with disease activity in systemic lupus erythematosus. Clin Rheumatol 2004;23:225-9
   PubMed Web of Science ®Google Scholar
• Wong CK, Lit LC, Tam LS, et al. Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus: implications for Th17-mediated inflammation in auto-immunity. Clin Immunol 2008;127:385-93
   PubMed Web of Science ®Google Scholar
• Lit LC, Wong CK, Tam LS, et al. Raised plasma concentration and ex vivo production of inflammatory chemokines in patients with systemic lupus erythematosus. Ann Rheum Dis 2006;65:209-15
   PubMed Web of Science ®Google Scholar
• Schwartz N, Michaelson JS, Putterman C. Lipocalin-2, TWEAK, and Other Cytokines as Urinary Biomarkers for Lupus Nephritis. Ann NY Acad Sci 2007;1109:265-74
   PubMed Web of Science ®Google Scholar
• Tso TK, Huang W, Huang H, Chang C. Relationship of plasma interleukin-18 concentrations to traditional and non-traditional cardiovascular risk factors in patients with systemic lupus erythematosus. Rheumatology 2006;45:1148-1153
   PubMed Web of Science ®Google Scholar
• Capper ER, Maskill JK, Gordon C, Blakemore AI. Interleukin (IL)-10, IL-1ra and IL-12 profiles in active and quiescent systemic lupus erythematosus: could longitudinal studies reveal patient subgroups of differing pathology? Clin Exp Immunol 2004;138:348-56
   PubMed Web of Science ®Google Scholar
• Akkoc T, de Koning PJ, Rückert B, et al. Increased activation-induced cell death of high IFN-gamma-producing T(H)1 cells as a mechanism of T(H)2 predominance in atopic diseases. J Allergy Clin Immunol 2008;121:652-8
   PubMed Web of Science ®Google Scholar
• Bullens DM, Truyen E, Coteur L, et al. IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx? Respir Res 2006;7:135
   PubMed Web of Science ®Google Scholar
• Betsi GI, Papadavid E, Falagas ME. Probiotics for the treatment or prevention of atopic dermatitis: a review of the evidence from randomized controlled trials. Am J Clin Dermatol 2008;9:93-103
   PubMed Web of Science ®Google Scholar
• Erin EM, Zacharasiewicz AS, Nicholson GC, et al. Rapid effect of inhaled ciclesonide in asthma: a randomized, placebo-controlled study. Chest 2008;134:740-5
   PubMed Web of Science ®Google Scholar
• Bensch GW, Nelson HS, Borish LC. Evaluation of cytokines in nasal secretions after nasal antigen challenge: lack of influence of antihistamines. Ann Allergy Asthma Immunol 2002;88:457-62
   PubMed Web of Science ®Google Scholar
• Hellman L. Therapeutic vaccines against IgE-mediated allergies. Expert Rev Vaccines 2008;7:193-208
   PubMed Web of Science ®Google Scholar
• Giordano A, Frontini A, Cinti S. Adipose organ nerves revealed by immunohistochemistry. Methods Mol Biol 2008;456:83-95
   PubMedGoogle Scholar
• Hamdy O, Porramatikul S, Al-Ozairi E. Metabolic obesity: the paradox between visceral and subcutaneous fat. Curr Diabetes Rev 2006;2:367-73
   PubMedGoogle Scholar
• Bahceci M, Gokalp D, Bahceci S, et al. The correlation between adiposity and adiponectin, tumor necrosis factor alpha, interleukin-6 and high sensitivity C-reactive protein levels. Is adipocyte size associated with inflammation in adults? J Endocrinol Invest 2007;30:210-14
   PubMed Web of Science ®Google Scholar
• Olszanecka-Glinianowicz M, Zahorska-Markiewicz B, Janowska J, Zurakowski A. Serum concentrations of nitric oxide, tumor necrosis factor (TNF)-alpha and TNF soluble receptors in women with overweight and obesity. Metabolism 2004;53:1268-73
   PubMed Web of Science ®Google Scholar
• Khaodhiar L, Ling PR, Blackburn GL, Bistrian BR. Serum levels of interleukin-6 and C-reactive protein correlate with body mass index across the broad range of obesity. JPEN J Parenter Enteral Nutr 2004;28:410-15
   PubMed Web of Science ®Google Scholar
• Choi KM, Lee J, Lee KW, et al. Comparison of serum concentrations of C-reactive protein, TNF-alpha, and interleukin 6 between elderly Korean women with normal and impaired glucose tolerance. Diabetes Res Clin Pract 2004;64:99-106
   PubMed Web of Science ®Google Scholar
• Nogueira-Machado JA, Chaves MM. From hyperglycemia to AGE-RAGE interaction on the cell surface: a dangerous metabolic route for diabetic patients. Expert Opin Ther Targets 2008;12:871-82
   PubMed Web of Science ®Google Scholar
• Herder C, Kolb H, Koenig W, et al. Association of systemic concentrations of macrophage migration factor with impaired glucose tolerance and type 2 diabetes: results from the Cooperative Health Research in the Region of Augsburg, Survey 4 (KORA S4). Diabetes Care 2006;29:368-71
   PubMed Web of Science ®Google Scholar
• Guest CB, Park MJ, Johnson DR, Freund GG. The implication of proinflammatory cytokines in type 2 diabetes. Front Biosci 2008;13:5187-94
   PubMed Web of Science ®Google Scholar
• Gohda T, Tanimoto M, Moon JY, et al. Increased serum endogenous secretory receptor for advanced glycation end-product (esRAGE) levels in type 2 diabetic patients with decreased renal function. Diabetes Res Clin Pract 2008;81:196-201
   PubMed Web of Science ®Google Scholar
• Garcia-Macedo R, Sanchez-Muñoz F, Almanza-Perez JC, et al. Glycine increases mRNA adiponectin and diminishes pro-inflammatory adipokines expression in 3T3-L1 cells. Eur J Pharmacol 2008;587:317-21
   PubMed Web of Science ®Google Scholar
• Schmidt AM, Stern DM. Receptor for age (RAGE) is a gene within the major histocompatibility class III region: implications for host response mechanisms in homeostasis and chronic disease. Front Biosci 2001;6:D1151-60
   PubMed Web of Science ®Google Scholar
• Young JL, Libby P, Schönbeck U. Cytokines in the pathogenesis of atherosclerosis. Thromb Haemost 2002;88:554-67
   PubMed Web of Science ®Google Scholar
• Libby P. Changing concepts of atherogenesis. J Intern Med 2000;247:349-58
   PubMed Web of Science ®Google Scholar
• Libby P, Sukhova G, Lee RT, Galis ZS. Cytokines regulate vascular functions related to stability of the atherosclerotic plaque. J Cardiovasc Pharmacol 1995;25:S9-12
   PubMedGoogle Scholar
• Fisman EZ, Adler Y, Tenenbaum A. Biomarkers in cardiovascular diabetology: interleukins and matrixins. Adv Cardiol 2008;45:44-64
   PubMed Web of Science ®Google Scholar
• Ehrin JA, Morrow DA, Sabarine MS. Inflammatory biomarkers in acute coronary syndromes. Circulation 2006;113:e72-5
   PubMed Web of Science ®Google Scholar
• Schulz C, Schäfer A, Stolla M, et al. Chemokine fractalkine mediates leukocyte recruitment to inflammatory endothelial cells in flowing whole blood: a critical role for P-selectin expressed on activated platelets. Circulation 2007;116:764-7
   PubMed Web of Science ®Google Scholar
• Blankenberg S, Tiret L, Bickel C, et al. Interleukin-18 is a strong predictor of cardiovascular death in stable and unstable angina. Circulation 2003;107:e206-7
   PubMedGoogle Scholar
• Zirlik A, Abdullah SM, Gerdes N, et al. Interleukin-18, the metabolic syndrome, and subclinical atherosclerosis: results from the Dallas Heart Study. Arterioscler Thromb Vasc Biol 2007;27:2043-9
   PubMed Web of Science ®Google Scholar
• Nishii M, Inomata T, Takehana H, et al. Serum levels of interleukin-10 on admission as a prognostic predictor of human fulminant myocarditis. J Am Coll Cardiol 2004;44:1292-7
   PubMed Web of Science ®Google Scholar
• Tousoulis D, Antoniades C, Vassiliadou C, et al. Effects of combined administration of low dose atorvastatin and vitamin E on inflammatory markers and endothelial function in patients with heart failure. Eur J Heart Fail 2005;7:1126-32
   PubMed Web of Science ®Google Scholar
• Brili S, Tousoulis D, Antoniades C, et al. Effects of ramipril on endothelial function and the expression of proinflammatory cytokines and adhesion molecules in young normotensive subjects with successfully repaired coarctation of aorta: a randomized cross-over study. J Am Coll Cardiol 2008;51:742-9
   PubMed Web of Science ®Google Scholar
• Colbert LH, Visser M, Simonsick EM, et al. Physical activity, exercise, and inflammatory markers in older adults: findings from the Health, Aging and Body Composition Study. J Am Geriatr Soc 2004;52:1098-104
   PubMed Web of Science ®Google Scholar
• Yaffe K, Lindquist K, Penninx BW, et al. Inflammatory markers and cognition in well-functioning African-American and white elders. Neurology 2003;61:76-80
   PubMed Web of Science ®Google Scholar
• Visser M, Pahor M, Taaffe DR, et al. Relationship of interleukin-6 and tumor necrosis factor-alpha with muscle mass and muscle strength in elderly men and women: the Health ABC Study. J Gerontol A Biol Sci Med Sci 2002;57:M326-32
   PubMed Web of Science ®Google Scholar
• Schaap LA, Pluijm SM, Deeg DJ, Visser M. Inflammatory markers and loss of muscle mass (sarcopenia) and strength. Am J Med 2006;119:526.e9-17
   PubMed Web of Science ®Google Scholar
• Alley DE, Crimmins EM, Karlamangla A, et al. Inflammation and rate of cognitive change in high-functioning older adults. J Gerontol A Biol Sci Med Sci 2008;63:50-5
   PubMed Web of Science ®Google Scholar
• Weaver JD, Huang MH, Albert M, et al. Interleukin-6 and risk of cognitive decline: MacArthur studies of successful aging. Neurology 2002;59:371-8
   PubMed Web of Science ®Google Scholar
• Taaffe DR, Harris TB, Ferrucci L, et al. Cross-sectional and prospective relationships of interleukin-6 and C-reactive protein with physical performance in elderly persons: MacArthur studies of successful aging. J Gerontol A Biol Sci Med Sci 2000;55:M709-15
   PubMed Web of Science ®Google Scholar
• van den Biggelaar AH, Gussekloo J, de Craen AJ, et al. Inflammation and interleukin-1 signaling network contribute to depressive symptoms but not cognitive decline in old age. Exp Gerontol 2007;42:693-701
   PubMed Web of Science ®Google Scholar
• Dheen ST, Kaur C, Ling EA. Microglial activation and its implications in the brain diseases. Curr Med Chem 2007;14:1189-97
   PubMed Web of Science ®Google Scholar
• Feldman HH, Jacova C, Robillard A, et al. Diagnosis and treatment of dementia: 2. Diagnosis. CMAJ 2008;178:825-36
   PubMed Web of Science ®Google Scholar
• Vassiliadis S, Relakis K, Papageorgiou A, Athanassakis I. Endometriosis and infertility: a multi-cytokine imbalance versus ovulation, fertilization and early embryo development. Clin Dev Immunol 2005;12:125-9
   PubMed Web of Science ®Google Scholar
• Fukui A, Kwak-Kim J, Ntrivalas E, et al. Intracellular cytokine expression of peripheral blood natural killer cell subsets in women with recurrent spontaneous abortions and implantation failures. Fertil Steril 2006;89:157-65
   Web of Science ®Google Scholar
• Ng SC, Gilman-Sachs A, Thaker P, et al. Expression of intracellular Th1 and Th2 cytokines in women with recurrent spontaneous abortion, implantation failures after IVF/ET or normal pregnancy. Am J Reprod Immunol 2002;48:77-86
   PubMed Web of Science ®Google Scholar
• Clark DA, Croitoru K. TH1/TH2,3 imbalance due to cytokine-producing NK, gammadelta T and NK-gammadelta T cells in murine pregnancy decidua in success or failure of pregnancy. Am J Reprod Immunol 2001;45:257-65
   PubMed Web of Science ®Google Scholar
• International Organization for Standardization. Available from: http://www.iso.org/iso/search.htm?qt=10993&searchSubmit=Search&sort=rel&type=simple&published=true.
   Google Scholar
• Varela MP, Kimmel PL, Phillips TM, et al. Biocompatibility of hemodialysis membranes: interrelations between plasma complement and cytokine levels. Blood Purif 2001;19:370-9
   PubMed Web of Science ®Google Scholar
• Cruz DN, de Cal M, Ronco C. Oxidative stress and anemia in chronic hemodialysis: the promise of bioreactive membranes. Contrib Nephrol 2008;161:89-98
   PubMed Web of Science ®Google Scholar
• Memoli B, Minutolo R, Bisesti V, et al. Changes of serum albumin and C-reactive protein are related to changes of interleukin-6 release by peripheral blood mononuclear cells in hemodialysis patients treated with different membranes. Am J Kidney Dis 2002;39:266-73
   PubMed Web of Science ®Google Scholar
• Thimm BW, Unger RE, Neumann HG, Kirkpatrick CJ. Biocompatibility studies of endothelial cells on a novel calcium phosphate/SiO2-xerogel composite for bone tissue engineering. Biomed Mater 2008;3:15007
   Google Scholar
• Perassi FT, Filho IB, Berbert FL, et al. Secretion of tumor necrosis factor-alpha by mouse peritoneal macrophages in the presence of dental sealers, sealapex and endomethasone. J Endod 2004;30:534-7
   PubMed Web of Science ®Google Scholar
• Chamberlain LM, Godek ML, Gonzalez-Juarrero M, Grainger DW. Phenotypic non-equivalence of murine (monocyte-) macrophage cells in biomaterial and inflammatory models. J Biomed Mater Res A 2008; published online 20 March 2008, doi:10.1002/jbm.a.31930
   Google Scholar