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Editorial

Medulloblastoma: need for targeted treatment

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Pages 649-652 | Published online: 10 Jan 2014

References

  • Kaaijk P, Schouten-van Meeteren AY, Slotman BJ, Kaspers GJ. Past, current and future protocols for combined modality therapy in childhood medulloblastoma. Expert Rev. Anticancer Ther.3, 79–90 (2003).
  • Burstein S. Growth disorders after cranial radiation in childhood. J. Clin. Endocrinol. Metab.78, 1280–1281 (1994).
  • Ogilvy-Stuart AL, Clayton PE, Shalet SM. Cranial irradiation and early puberty. J. Clin. Endocrinol. Metab.78, 1282–1286 (1994).
  • Mulhern RK, Merchant TE, Gajjar A, Reddick WE, Kun LE. Late neurocognitive sequelae in survivors of brain tumours in childhood. Lancet Oncol.5, 399–408 (2004).
  • Grill J, Renaux VK, Bulteau C et al. Long-term intellectual outcome in children with posterior fossa tumors according to radiation doses and volumes. Int. J. Radiat. Oncol. Biol. Phys.45, 137–145 (1999).
  • Ris MD, Packer R, Goldwein J, Jones-Wallace D, Boyett JM. Intellectual outcome after reduced-dose radiation therapy plus adjuvant chemotherapy for medulloblastoma: a Children's Cancer Group study. J. Clin. Oncol.19, 3470–3476 (2001).
  • Buter J, Giaccone G. Medical treatment of non-small-cell lung cancer. Ann. Oncol.16(Suppl. 2), ii229–ii232 (2005).
  • Marino S. Medulloblastoma: developmental mechanisms out of control. Trends Mol. Med.11, 17–22 (2005).
  • Berman DM, Karhadkar SS, Hallahan AR et al. Medulloblastoma growth inhibition by hedgehog pathway blockade. Science297, 1559–1561 (2002).
  • Romer J, Curran T. Targeting medulloblastoma: small-molecule inhibitors of the sonic hedgehog pathway as potential cancer therapeutics. Cancer Res.65, 4975–4978 (2005).
  • Pomeroy SL, Tamayo P, Gaasenbeek M et al. Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature415, 436–442 (2002).
  • Li XN, Shu Q, Su JM, Perlaky L, Blaney SM, Lau CC. Valproic acid induces growth arrest, apoptosis, and senescence in medulloblastomas by increasing histone hyperacetylation and regulating expression of p21Cip1, CDK4, CMYC. Mol. Cancer Ther.4, 1912–1922 (2005).
  • Wang Q, Li H, Wang XW, Wu DC, Chen XY, Liu J. Resveratrol promotes differentiation and induces Fas-independent apoptosis of human medulloblastoma cells. Neurosci. Lett.351, 83–86 (2003).
  • Stockhammer G, Manley GT, Johnson R, Rosenblum MK, Samid D, Lieberman FS. Inhibition of proliferation and induction of differentiation in medulloblastoma- and astrocytoma-derived cell lines with phenylacetate. J. Neurosurg.83, 672–681 (1995).
  • Li XN, Parikh S, Shu Q et al. Phenylbutyrate and phenylacetate induce differentiation and inhibit proliferation of human medulloblastoma cells. Clin. Cancer Res.10, 1150–1159 (2004).
  • Block KI. Antioxidants and cancer therapy: furthering the debate. Integr. Cancer Ther.3, 342–348 (2004).
  • Prasad KN. Multiple dietary antioxidants enhance the efficacy of standard and experimental cancer therapies and decrease their toxicity. Integr. Cancer Ther.3, 310–322 (2004).
  • Borek C. Dietary antioxidants and human cancer. Integr. Cancer Ther.3, 333–341 (2004).
  • Rutz HP, Little JB. Modification of radiosensitivity and recovery from X ray damage in vitro by retinoic acid. Int. J. Radiat. Oncol. Biol. Phys.16, 1285–1288 (1989).
  • Katoh M. Regulation of WNT signaling molecules by retinoic acid during neuronal differentiation in NT2 cells: threshold model of WNT action. Int. J. Mol. Med.10, 683–687 (2002).
  • Hininger I, Waters R, Osman M et al. Acute prooxidant effects of vitamin C in EDTA chelation therapy and long-term antioxidant benefits of therapy. Free Radic. Biol. Med.38, 1565–1570 (2005).
  • Sartor CI. Mechanisms of disease: radiosensitization by epidermal growth factor receptor inhibitors. Nature Clin. Pract. Oncol.1, 80–87 (2004).
  • Gilbertson RJ, Perry RH, Kelly PJ, Pearson AD, Lunec J. Prognostic significance of HER2 and HER4 coexpression in childhood medulloblastoma. Cancer Res.57, 3272–3280 (1997).
  • Bowers G, Reardon D, Hewitt T et al. The relative role of ErbB1–4 receptor tyrosine kinases in radiation signal transduction responses of human carcinoma cells. Oncogene20, 1388–1397 (2001).
  • Dittmann K, Mayer C, Fehrenbacher B et al. Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase. J. Biol. Chem.280, 31182–31189 (2005).
  • Harari PM, Huang SM. Radiation response modification following molecular inhibition of epidermal growth factor receptor signaling. Semin. Radiat. Oncol. 11, 281–289 (2001).
  • Sminia P, Kuipers G, Geldof A, Lafleur V, Slotman B. COX-2 inhibitors act as radiosensitizer in tumor treatment. Biomed. Pharmacother.599(Suppl. 2), S272–S275 (2005).
  • Patti R, Gumired K, Reddanna P, Sutton LN, Phillips PC, Reddy CD. Overexpression of cyclooxygenase-2 (COX-2) in human primitive neuroectodermal tumors: effect of celecoxib and rofecoxib. Cancer Lett.180, 13–21 (2002).
  • Raju U, Ariga H, Dittmann K, Nakata E, Ang KK, Milas L. Inhibition of DNA repair as a mechanism of enhanced radioresponse of head and neck carcinoma cells by a selective cyclooxygenase-2 inhibitor, celecoxib. Int. J. Radiat. Oncol. Biol. Phys.63, 520–528 (2005).
  • Ranatunge RR, Garvey DS, Janero DR et al. Synthesis and selective cyclooxygenase-2 (COX-2) inhibitory activity of a series of novel bicyclic pyrazoles. Bioorg. Med. Chem.12, 1357–1366 (2004).
  • Luo JL, Kamata H, Karin M. IKK/NF-κB signaling: balancing life and death – a new approach to cancer therapy. J. Clin. Invest.115, 2625–2632 (2005).

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