Systemic and global toxicities of head and neck treatment

References

• Wilson IB, Cleary PD. Health-related quality of life, a conceptual model of patient outcomes. JAMA273, 59–63 (1995).
   PubMed Web of Science ®Google Scholar
• Hickok JT, Morrow GR, Roscoe JA, Mustian K, Okunieff P. Occurrence, severity, and longitudinal course of twelve common symptoms in 1129 consecutive patients during radiotherapy for cancer. J. Pain Symptom. Manage.30, 433–442 (2005).
   PubMed Web of Science ®Google Scholar
• Maccormick RE. Possible acceleration of aging by adjuvant chemotherapy: a cause of early onset frailty? Med. Hypotheses67, 212–215 (2006).
   PubMed Web of Science ®Google Scholar
• Danzer R, Bluthe RM, Kent S, Goodall G. Behavioral effects of cytokines: an insight into mechanisms of sickness behavior. J. Neurosci. Methods17, 130–150 (1993).
   Google Scholar
• Pusztai L, Mendoza TR, Reuben JM et al. Changes in plasma levels of inflammatory cytokines in response to paclitaxel chemotherapy. Cytokine25, 94–102 (2004).
   PubMed Web of Science ®Google Scholar
• Bower JE, Ganz PA, Aziz N, Fahey JL. Fatigue and proinflammatory cytokine activity in breast cancer survivors. Psychosom. Med.64, 604–611 (2002).
   PubMed Web of Science ®Google Scholar
• Chansky K, Benedetti J, Macdonald JS. Differences in toxicity between men and women treated with 5-fluorouracil therapy for colorectal carcinoma. Cancer103, 1165–1171 (2005).
   PubMed Web of Science ®Google Scholar
• McCollum AD, Catalano PJ, Haller DG et al. Outcomes and toxicity in African American and Caucasian patients in a randomized adjuvnat trial for colon cancer. J. Natl Cancer Inst.39, 91–100 (2002).
   Google Scholar
• Vera-Llonch M, Oster G, Hagiwara M et al. Oral mucositis in patients undergoing radiation treatment for head and neck carcinoma. Cancer106, 329–336 (2006).
   PubMed Web of Science ®Google Scholar
• Barasch A, Peterson DE. Risk factors for ulcerative oral mucositis in cancer patients: unanswered questions. Oral Oncol.39, 91–100 (2003).
   PubMed Web of Science ®Google Scholar
• Bjarnason GA, Mackenzie R, Hodson I et al. A randomized prospective Phase-III study comparing the acute oral mucositis of morning vs. afternoon radiotherapy (RT) in patients (pts) with squamous cell carcinoma of the head and neck (SCCHN): NCIC-CTG HN.3. Proc. Am. Soc. Clin. Oncol.23, 500 (2005) (Abstract 5500).
   Google Scholar
• Anthony L, Bowen J, Garden A, Hewson I, Sonis S. New thoughts on the pathobiology of regimen-related mucosal injury. Support. Care Cancer14, 516–518 (2006).
   PubMed Web of Science ®Google Scholar
• Worthington HV, Clarkson JE, Eden OB. Interventions for preventing oral mucositis for patients with cancer receiving treatment. Cochrane Database Syst. Rev.2, CD000978 (2007).
   Google Scholar
• Trotti A, Bellm LA, Epstein JB et al. Mucositis incidence, severity and associated outcomes in patients with head and neck cancer receiving radiotherapy with or without chemotherapy: a systematic literature review. Radiother. Oncol.66, 253–262 (2003).
   PubMed Web of Science ®Google Scholar
• Sonis ST. The pathobiology of mucositis. Nat. Rev. Cancer4, 277–284 (2004).
   PubMed Web of Science ®Google Scholar
• Sonis ST, Elting LS, Keefe D. Perspectives on cancer therapy-induced mucosal injury pathogenesis, measurement, epidemiology, and consequences for patients. Cancer100(Suppl.), 1995–2025 (2004).
   PubMed Web of Science ®Google Scholar
• Blijlevens N, Sonis S. Palifermin (recombinant keratinocyte growth factor-1): a pleiotropic growth factor with multiple biological activities in preventing chemotherapy- and radiotherapy-induced mucositis. Ann. Oncol.18(5), 817–826 (2007).
   PubMed Web of Science ®Google Scholar
• Logan RM, Gobson RJ, Sonis S, Keefe D. Nuclear factor-κB (NF-κB) and cyclooxygenase-2 (COX-2) expression in the oral mucosa following cancer chemotherapy. Oral Oncol.43(4), 395–401 (2006).
   PubMed Web of Science ®Google Scholar
• Trotti A. Toxicity in head and neck cancer: a review of trends and issues. Int. J. Radiat. Oncol. Biol. Phys.47, 1–12 (2000).
   PubMed Web of Science ®Google Scholar
• Duncan GG, Epstein JB, Tu D et al. Quality of life, mucositis, and xerostomia from radiotherapy for head and neck cancers: a report from the NCIC CTG HN2 randomized trial of an antimicrobial lozenge to prevent mucositis. Head Neck27, 421–428 (2005).
   PubMed Web of Science ®Google Scholar
• Wong PC, Dodd, MJ, Miaskowski C et al. Mucositis pain induced by radiation therapy: prevalence, severity, and use of self-care behaviors. J. Pain Symptom Manage.32, 27–37 (2006).
   PubMed Web of Science ®Google Scholar
• Isitt J, Murphy BA, Beaumont JL et al. Oral mucositis (OM) related morbidity and resource utilization is a prospective study of head and neck cancer (HNC) patients. Proc. Am. Soc. Clin. Oncol.24, 289 (2006) (Abstract 5539).
   Google Scholar
• Chau KS, Reddy SK, Lee MC, Patt RB. Pain and loss of function in head and neck cancer survivors. J. Pain Symptom Manage.18, 193–202 (1999).
   PubMed Web of Science ®Google Scholar
• Murphy BA, Cmelak A, Bayles S, Dowling E, Billante C. Head and neck cancer. In: Oxford Textbook of Palliative Medicine. Oxford University Press, Oxford, UK 658–672 (2004).
   Google Scholar
• Dewys WD, Begg C, Lavin PT et al. Prognostic effect of weight loss prior to chemotherapy in cancer patients. Am. J. Medicine69, 491–497 (1980).
   PubMed Web of Science ®Google Scholar
• Brookes GB. Nutritional status – a prognostic indicator in head and neck cancer. Otolaryngol. Head Neck Surg.93, 69–74 (1985).
   PubMed Web of Science ®Google Scholar
• Lees J. Incidence of weight loss in head and neck cancer patients on combined radiotherapy treatment at a regional oncology centre. Int. J. Radiat. Oncol. Biol. Phys.36, 1205–1209 (1999).
   Google Scholar
• Lin A, Jabbari S, Worden FP et al. Metabolic abnormalities associated with weight loss during chemoirradiation of head and neck cancer. Int. J. Radiation Biol. Phys.63, 1413–1418 (2005).
   PubMed Web of Science ®Google Scholar
• Lee JH, Machtay M, Unger LD et al. Prophylactic gastrostomy tubes in patients undergoing intensive irradiation for cancer of the head and neck. Arch. Otolaryngol. Head Neck Surg.124(8), 871–875 (1998).
   PubMed Web of Science ®Google Scholar
• Tyldesley S, Sheehan F, Munk P et al. The use of radiologically placed gastrostomy tubes in head and neck cancer patients receiving radiotherapy. Int. J. Radiat. Oncol. Biol. Phys.36, 1205–1209 (1996).
   PubMed Web of Science ®Google Scholar
• Gianotti L, Braga M, Radaelli G, Mariani L, Vignali A, Di Carlo V. Lack of improvement of prognostic performance of weight loss when combined with other parameters. Nutrition105, 62–73 (1995).
   Google Scholar
• Murphy BA, Friedmann J, Dowling E, Cheatham R, Cmelak A. Dietary intake and adapations in head and neck cancer patients treated with chemoradiation. Proc. Am. Soc. Clin. Oncol.21 (2002) (Abstract 932).
   Google Scholar
• Silver HJ, Wellman NS, Arnold DJ, Livingstone AS, Byers PM. Older adults on home enteral nutrition: enteral regimen, provider involvement, and health care outcomes. JPEN J. Parenter. Enteral. Nutr.28(2), 92–98 (2004).
   PubMed Web of Science ®Google Scholar
• Murphy BA, Lewin J, Ridner S, Trotti A. Mechanism of weight loss in head and neck cancer patients treated with chemoradiation. In: American Society of Clinical Oncolgoy 2006 Educational Book. American Society of Clinical Oncology, VA, USA 340–344 (2006).
   Google Scholar
• Silver HJ, Dietrich MS, Murphy BA. Loss of lean body mass and associated physical function decline in the context of increased energy expenditure and inflammatory state in head and neck cancer patients undergoing concurrent chemo-radiation therapy. Head Neck (2007) (In press).
   Google Scholar
• Rosenthal DI, Lewin J, Eisbruch A. Prevention and treatment of dysphagia and aspiration after chemoradiation for head and neck cancer. J. Clin. Oncol.24, 2636–2643 (2006).
   PubMed Web of Science ®Google Scholar
• Murphy BA, Smith K, Dowling E, Cmelak A, Burkey B, Forastiere A. Swallowing function for patients treated on E2399, a Phase II trial of function preservation with induction paclitaxel/carboplatin followed by radiation plus weekly paclitaxel. Proc. Am. Soc. Clin. Oncol.24, 286 (2006) (Abstract 5524).
   Google Scholar
• van Wilgen CP, Dijstra PU, van der Laan BF, Plukker JTM, Roodenburg JL. Morbidity of the neck after head and neck cancer therapy. Head Neck26, 785–791 (2004).
   PubMed Web of Science ®Google Scholar
• Cappiello J, Piazza C, Giudice M, De Maria G, Nicolai P. Shoulder disability after different selective neck dissections (level II–IV versus levels II–V): a comparative study. Laryngoscope115, 259–263 (2005).
   PubMed Web of Science ®Google Scholar
• Silver HJ, Horn PS, Murphy BA. Relationship between body composition changes, inflammation and physical functionality in head and neck cancer patients undergoing concurrent chemoradiation. FASEB J.20, A143 (2006).
   Google Scholar
• Mitchell SA, Berger AM. Cancer-related fatigue: the evidence base for assessment and management. Cancer J.12, 374–387 (2006).
   PubMed Web of Science ®Google Scholar
• Conn VS, Hafdahl AR, Porock DC, McDaniel R, Nielsen PJ. A meta-analysis of exercise interventions among people treated for cancer. Support. Care Cancer14, 699–712 (2006).
   PubMed Web of Science ®Google Scholar
• Dantzer R, Kelley KW. Twenty years of research in cytokine-induced sickness behavior. Brain Behav. Immun.21(2), 153–160 (2007).
   PubMed Web of Science ®Google Scholar
• Dantzer R, Kelley KW. Stress and immunity: an integrated view of the relationship between the brain and the immune system. Life Sci.44, 1995–2008 (1989).
   PubMed Web of Science ®Google Scholar
• Taylor JC, Terrell JE, Ronis DL et al. Disability in patients with head and neck cancer. Arch. Otolaryngol.130, 764–769 (2004).
   Google Scholar
• Disease of the Lymphatics. Browse N, Burnand KG, Mortimer PS (Eds). Arnold, London, UK (2003).
   Google Scholar
• Foldi M, Foldi E, Kubik S. Textbook of Lymphology for Physicians and Lymphedema Therapists. Urban & Fischer, Munchen, Germany (2003).
   Google Scholar
• Harris GJ, Woo KI, Schultz CJ et al. Late-onset chemosis in patients with head or neck tumors. Ophthal. Plast. Reconstr. Surg.20, 436–441 (2004).
   PubMed Web of Science ®Google Scholar
• Micke O, Bruns F, Mucke R et al. Selenium in the treatment of radiation-associated secondary lymphedema. Int. J. Radiation Oncology Biol. Phys.56, 40–49 (2003).
   PubMed Web of Science ®Google Scholar
• Fajardo LF. Effects of ionizing radiation on lymph nodes. Front. Radiat. Ther. Oncol.28, 37–45 (1994).
   PubMedGoogle Scholar
• Guyton AC, Hall JE. Textbook of Medical Physiology (10th Edition). Saunders, PA, USA (2000).
   Google Scholar
• Ridner SH. Breast cancer lymphedema: pathophysiology and risk reduction guidelines. Oncol. Nurs. Forum29, 1285–1293 (2002).
   PubMedGoogle Scholar
• Tabibiazar R, Cheung L, Han J et al. Inflammatory manifestations of experimental lymphatic insufficiency. PLoS Med.3, 1114–1139 (2006).
   Web of Science ®Google Scholar
• Zeller JL. High suicide risk for patients with head and neck cancer. JAMA296, 1716–1717 (2006).
   PubMed Web of Science ®Google Scholar
• Kendel W. Suicide and cancer: a gender-comparative study. Ann. Oncol.18, 381–387 (2007).
   PubMed Web of Science ®Google Scholar
• Zabora J, Brintzenhofeszoc K, Curbow B, Hooker C, Piantadosi S. The prevalence of psychological distress by cancer site. Psycho-oncology10, 19–28 (2001).
   PubMed Web of Science ®Google Scholar
• Haman K, Murphy B, Compas B. Social anxiety in head and neck cancer patients. Presented at: American Psychological Oncology Society Annual Meeting. Phoenix, AZ, USA, 27–29 January 2005.
   Google Scholar
• Haman K, Smith B, Murphy B, Compas B. Predictors of quality of life in head and neck cancer patients. Presented at: American Psychological Oncological Society Annual Meeting. Amelia Island, FL, USA, 16–19 February (2006).
   Google Scholar
• Sullivan MD, Edlund MJ, Zhang L et al. Association between mental health disorders, problem drug use and regular prescription opioid use. Arch. Intern. Med.166, 2087–2093 (2006).
   PubMed Web of Science ®Google Scholar
• Reiger DA, Farmer ME, Rae DS et al. Comorbidity of mental disorders with alcohol and other drug abuse. JAMA264, 2511–2518 (1990).
   PubMed Web of Science ®Google Scholar
• Harris DS, Wolkowitz OM, Reus VI. Psychoneuroendocrinology In: Kaplan and Sadock’s Comprehensive Textbook of Psychiatry (8th Edition). Lippincott Williams & Wilkins, MD, USA 126–137 (2005).
   Google Scholar
• Raison CL, Capupron L, Miller AH. Cytokines sing the blues: inflammation and the pathogenesis of depression. Trends Immunol.27, 24–31 (2006).
   PubMed Web of Science ®Google Scholar
• Schiepers OJG, Wichers MC, Maes M. Cytokines and major depression. Prog. Neuropsychopharmacol. Biol. Psychiatry29, 201–217 (2005).
   PubMed Web of Science ®Google Scholar
• Kenis G, Maes M. Effects of antidepressants on the production of cytokines. Int. J. Neuropsychopharmacol.5, 401–412 (2002).
   PubMed Web of Science ®Google Scholar
• Leonard BE. The immune system, depression and the action of antidepressants. Prog. Neuropsychopharmacol. Biol. Psychiatry25, 767–780 (2001).
   PubMed Web of Science ®Google Scholar
• Pitsavos C, Panagiotakos DB, Papageorgiou C et al. Anxiety in relation to inflammation and coagulation markers, among healthy adults: the ATTICA Study. Atherosclerosis185, 320–326 (2006).
   PubMed Web of Science ®Google Scholar
• Melmamed S, Shirom A, Toker S et al. Association of fear of terror with low-grade inflammation among apparently healthy employed adults. Psychosom. Med.66, 484–491 (2004).
   PubMed Web of Science ®Google Scholar
• Rapaport MH, Stein MB. Serum cytokine and soluble interleukin-2 receptors in patients with panic disorder. Anxiety1, 22–25 (1999).
   Google Scholar