Molecular typing methods for the epidemiological identification of Clostridium difficile strains

References

• Kelly CP, LaMont JT. Clostridium difficile infection. Ann. Rev. Med. 49, 375–390 (1998).
   Web of Science ®Google Scholar
• • A review of C. difficile disease, diagnosis and treatment.
   Google Scholar
• Lyerly DM, Krivan HC, Wilkins TD. Clostridium difficile: its disease and toxins. Clin. Microbiol. Rev. 1, 1–18 (1988).
   Google Scholar
• Nath SK, Thornley JH, Kelly M et al. A sustained outbreak of Clostridium difficile in a general hospital: persistence of a toxigenic clone in four units. Infect. Control Hosp. Epidemiol. 15, 182–189 (1994).
   Web of Science ®Google Scholar
• Testore GP, Pantosi A, Cerquetti M, Babudieri S et al. Evidence of crossinfection in an outbreak of Clostridium difficile associated diarrhea in a surgical unit. J. Med. Microbiol. 26, 125–128 (1988).
   Web of Science ®Google Scholar
• Burdon DW. Clostridium difficile: the epidemiology and prevention of hospital acquired infection. Infection 10, 203–204 (1982).
   Web of Science ®Google Scholar
• Rafferty ME, Baltch AL, Smith RP et al. Comparison of restriction enzyme analysis, arbitrarily primed PCR and protein profile analysis typing for epidemiological investigation of an ongoing Clostridium difficile outbreak. J. Clin. Microbiol. 36, 2957–2963 (1998).
   Web of Science ®Google Scholar
• Delmee M, Homel M, Wauters G. Serogrouping of Clostridium difficile strains by slide agglutination. J. Clin. Microbiol. 21, 323–327 (1985).
   Google Scholar
• • Original description of the methodology used for serogrouping C. difficile.
   Google Scholar
• Toma S, Lesiak G, Magus M, Lo Ho Lau, Delmee M. Serotyping of Clostridium difficile. J. Clin. Microbiol. 26, 226–228 (1988).
   Google Scholar
• Van Dick P, Avesani V, Delmee M. Genotyping of outbreak related and sporadic Isolates of Clostridium difficile belonging to serogroup C. J. Clin. Microbiol. 34, 3049–3055 (1996).
   Google Scholar
• Depetrie C, Delmee M, Avesani V et al. Serogroup F strains of Clostridium difficile produce toxin B but no toxin A. J. Med. Microbiol. 38, 434–441 (1993).
   Web of Science ®Google Scholar
• Tabaqchali S, OFarrell S, Holland D, Silman R. Method for the typing of Clostrdium difficile based on polycacrylamide gel electrophoresis of [35S] methionine labeled proteins. J. Clin. Microbiol. 23, 197–198 (1986).
   Google Scholar
• • Detailed description of the methods for Radio PAGE of C. difficile strains.
   Google Scholar
• Mulligan ME, Halebian S, Kwok RYY et al. Bacterial agglutination and polyacrylamide gel electrophoresis for typing Clostridium difficile. J. Infect. Dis. 153, 267–271 (1986).
   Web of Science ®Google Scholar
• Mullligan ME, Peterson LRl, Kwok RYY, Clabots CR, Gerding DN. Immunoblots and plasmid fingerprints compared with serotyping and polyacrylamide gel electrophoresis for typing Clostridium difficile. J. Clin.Microbiol. 26, 41–46 (1988).
   Google Scholar
• • Original report on the use of immunoblot analysis to fingerprint C. difficile.
   Google Scholar
• Brazier J, Mulligan ME, Delmee M, Tabaqchali S et al. Preliminary findings of the International Typing Study on Clostridium difficile. Clin. Infect. Dis. 25\(Suppl. 2), S199–201 (1997).
   Google Scholar
• •• This important reference is the first attempt to standardize typing systems for C. difficile. It reports the preliminary findings of the International Typing Study Group.
   Google Scholar
• Clabots CR, Peterson LR, Gerding DN. Characterization of a nosocomial Clostridium difficile outbreak by using plasmid profile typing and clindamycin susceptibility testing. J. Infect. Dis. 158, 731–736 (1988).
   Google Scholar
• Arai T, Atsuko K, Satoshi N, Nakamura M. A survey of plasmids in Clostridium difficile strains. Kitasato Arch. Exp. Med. 57, 285–288 (1984).
   Google Scholar
• Steinberg JP, Beckerdite ME, Westenfelder GO. Plasmid profiles of Clostridium difficile isolates from patients with antibioticassociated colitis in two community hospitals. J. Infect. Dis. 156, 1036–1038 (1987).
   Google Scholar
• Wren BW, Tabaqchali S. Restriction endonuclease DNA analysis of Clostridium difficile. J. Clin. Microbiol. 25, 2402–2404 (1987).
   Web of Science ®Google Scholar
• • Description of methodology used for REA typing of C. difficile.
   Google Scholar
• Kuijper EDJ, Oudbier JH, Stuifbergen WNHM, Jansz A, Zanen HC. Application of whole cell DNA restriction endonuclease profiles to the epidemiology of Clostridium difficile-induced diarrhea. J. Clin. Microbiol. 25, 751–753 (1987).
   Google Scholar
• Peerbooms PGH, Kuijt P, Maclaren DM. Application of chromosomal restriction endonuclease digest analysis for use as typing method for Clostridium difficile. J. Clin. Pathol. 40, 771–776 (1987).
   Google Scholar
• Devlin HR, Au W, Foux L, Bradbury WC. Restriction endonuclease analysis of nosocomial isolates of Clostridium difficile. J. Clin. Microbiol. 25, 2168–2172 (1987).
   Web of Science ®Google Scholar
• Johnson S, Adelmann A, Clabots CR, Peterson LR, Gerding DN. Recurrences of Clostridium diffcile diarrhea not caused by the original infecting organism. J. Infect. Dis. 159, 340–343 (1989).
   Google Scholar
• ONeill GL, Beaman MH, Riley TV. Relapse versus reinfection with Clostridium difficile. Epidemiol .Infect. 107, 627–635 (1991).
   Web of Science ®Google Scholar
• Samore MH, Bettin KM, DeGirolami P, Gerding DN, Karchmer A. Epidemiology of Clostridium difficile at a tertiary care hospital: diversity of types by restriction endonuclease analysis (REA). Infect. Control Hosp. Epidemiol. 13, 760–761 (1994).
   Google Scholar
• Kristjansson M, Samore MH, Gerding DN et al. Comparison of restriction endonuclease analysis, ribotyping and pulsed-field gel electrophoresis for molecular differentiation of Clostridium difficile strains. J. Clin. Microbiol. 32, 1963–1969 (1994).
   Web of Science ®Google Scholar
• • A good comparison of several commonly used molecular typing methods.
   Google Scholar
• ONeill G, Adams JE, Bowman RA, Riley TV. A molecular characterization of Clostridium difficile isolates from humans, animals and their environments. Epidemiol. Infect. 111, 257–264 (1993).
   Web of Science ®Google Scholar
• McMilllin DE, Muldrow LL. Typing of toxin strains of Clostridium difficile using DNA fingerprints generated with arbitrary polymerase chain reaction primers. FEMS Microbiol. Lett. 92, 5–10 (1992).
   Web of Science ®Google Scholar
• Barbut FN, Maria N, Frottier J, Petit JC. Use of arbitrarily-primed polymerase chain reaction for investigating an outbreak of Clostridium difficile-associated diarrhea in AIDS patients. Eur. J. Clin. Microbiol. Infect. Dis. 12, 794–795 (1993).
   Web of Science ®Google Scholar
• Silva J, Jr., Tang YJ, Gumerlock PH. Genotyping of Clostridium difficile isolates. J. Infect. Dis. 169, 661–664 (1993).
   Web of Science ®Google Scholar
• Tang YJ, Houston ST, Gumerlock PH, Mulligan ME et al. Comparison of arbitrarily-primed PCR with restriction endonuclease and immunoblot analyses for typing Clostridium difficile isolates. J. Clin. Microbiol. 33, 3169–3173 (1995).
   Web of Science ®Google Scholar
• •• Report on the development of AP-PCR, validation of the technique and comparison with most common typing methods.
   Google Scholar
• Kilgore GE, Kato H. Use of arbitrary Primer PCR to type Clostridium difficile and comparison of results with those by immunoblot typing. J. Clin. Microbiol. 32, 1591–1593 (1994).
   Web of Science ®Google Scholar
• Collier MC, Stock F, DeGirolami PC, Samore MH, Cartwright CP. Comparison of PCR based approaches to molecular epidemiologic analysis of Clostridium difficile. J. Clin. Microbiol. 34, 1153–1157 (1996).
   Google Scholar
• Chachaty E, Saulnier P, Martin A, Mario N, Adremont A. Comparison of ribotyping, pulsed-field gel electrophoresis and random amplified polymorphic DNA for typing Clostridium difficile strains. FEMS Microbiol. Lett. 122, 61–68 (1994).
   Google Scholar
• Samore MH, Kristjansson M, Venkataraman L, DeGirolami PC, Arbeit RD. Comparison of arbitrarily-primed polymerase chain reaction, restriction enzyme analysis and pulsed-field gel electrophoresis for typing Clostridium difficile. J. Microbiol. Meth. 25, 215–224 (1996).
   Google Scholar
• Gutler V. Typing of Clostridium difficile strains by PCR amplification of variable length 16S23S rDNA spacer regions. J. Gen. Microbiol. 139, 3089–3097 (1993).
   Google Scholar
• ONeill GL, Ogunsola FT, Brazier JS, Duerden BI. Modification of a PCR ribotyping method for application as a routine typing scheme for Clostridium difficile. Anaerobe 2, 205–209 (1996).
   Web of Science ®Google Scholar
• • Report on a sensitive PCR ribotyping scheme for C. difficile.
   Google Scholar
• Bidet P, Barbut F, Lalande V, Burghoffer B, Petit JC. Development of a new PCR ribotyping method for Clostridium difficile based on ribosomal RNA gene sequencing. FEMS Microbiol. Lett.. 175, 261–266 (1999).
   Google Scholar
• Maslow JN, Skutsky AM, Arbeit RD. Application of pulsed-field gel electrophoresis to molecular epidemiology. In: Diagnostic Molecular Microbiology Principles and Applications. Persing DH, Smith TF, Tenover FC, White TJ (Eds.), American Society for Microbiology, Washington, DC, USA, 563–572 (1993).
   Google Scholar
• Talon D, Bailly P, Delmee M et al. Use of pulsed-field gel electrophoresis for investigation of an outbreak of Clostridium difficile infection among geriatric patients. Eur. J. Microbiol. Infect. Dis. 14, 987–993 (1995).
   Web of Science ®Google Scholar
• Kato H, Kato N, Watanabe K et al. Application of typing by pulsed-field gel electrophoresis to the study of Clostridium difficile in a neonatal intensive care unit. J. Clin. Microbiol. 32, 2067–2070 (1994).
   Web of Science ®Google Scholar
• Kato H, Kato N, Watanabe k, Ueno K, Sakata Y, Fujita K. Relapses or re-infections: analysis of a case of Clostridium difficile associated colitis by two typing systems. Curr. Microbiol. 33, 220–223 (1996).
   Web of Science ®Google Scholar
• Bidet P, Lalande V, Salauze B et al. Comparison of PCR ribotyping, arbitrarily primed PCR and pulsed-field gel electrophoresis for typing Clostridium difficile. J. Clin. Microbiol. 38, 2484–2487 (2000).
   Web of Science ®Google Scholar
• • Most recent report correlating the most commonly used molecular typing methods.
   Google Scholar
• Brazier J. The epidemiology and typing of Clostridium difficile. J. Antimicrob. Chemother. 41(Suppl.C), 47–57 (1998).
   Google Scholar
• •• Excellent overview of epidemiological aspects and typing of C. difficile.
   Google Scholar
• Dice LR. Measures of the amount of ecological association between species. Ecology 26, 297–302 (1945).
   Web of Science ®Google Scholar
• Tenover FC, Arbeit RD, Goering RV et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J. Clin. Microbiol. 33, 2233–2239 (1995).
   Web of Science ®Google Scholar
• Wilcox MH, Cunniffe JG, Trundle C, Redpath C. Financial burden of hospitalacquired Clostridium difficile infection. J. Hosp. Infect. 34, 23–30 (1996).
   PubMed Web of Science ®Google Scholar
• Kofsly P, Rosen L, Reed J, Tolmie M, Ufberg D. Clostridium difficile a common and costly colitis. Dis. Colon Rectum 34, 244–248 (1991).
   Google Scholar
• Cummings CA, Relman DA. Using DNA microarrays to study host-microbe interactions. Emerg. Infect. Dis. 6, 513–525 (2000).
   Web of Science ®Google Scholar
• Torres JP. Purification and characterization of toxin B from a strain of Clostridium difficile that does not produce toxin A. J. Med. Microbiol. 35, 40–44 (1991).
   Web of Science ®Google Scholar
• Braun V, Hundsberger T, Leukel P, Sauerborn M, von Eichel-Streiber C. Definition of a single integration site of the pathogenicity locus in Clostridium difficile. Gene 181, 29–38 (1996).
   Google Scholar
• Cohen SH, Tang YJ, Silva J, Jr. Analysis of the pathogenicity locus in Clostridium difficile strains. J. Infect. Dis. 181, 659–663 (2000).
   Web of Science ®Google Scholar
• •• The PaLoc is conserved in all toxigenic strains of C. difficile. This is the first paper analyzing a series of clinical isolates for the presence of the PaLoc genes.
   Google Scholar
• Rupnik M, Avesani V, Janc M, von Eichel- Streiber C, Delmee M. A novel toxinotyping scheme and correlation of toxinotypes with serogroups of Clostridium difficile isolates. J. Clin. Microbiol. 36, 2240–2247 (1998).
   Google Scholar
• Wozniak G, Trontelj P, Rupnik M. Genomic relatedness of Clostridium difficile strains from different toxinotypes and serogroups. Anaerobe 6, 261–267 (2000).
   Google Scholar