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Technology Report

Challenges for CTC-based liquid biopsies: low CTC frequency and diagnostic leukapheresis as a potential solution

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Pages 147-164 | Received 24 Jul 2015, Accepted 18 Nov 2015, Published online: 16 Dec 2015

References

  • Papers of special note have been highlighted as:
  • • of interest
  • •• of considerable interest
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• Describes the statistics of the different process steps that are needed for the isolation and detection of CTCs.

• This study describes a model developed to estimate tumor size and CTC concentration before distant metastasis occur.

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•• First paper describing the use of DLA in cancer patients.

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