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Review

Pharmacoeconomic considerations of tropisetron for prophylaxis and treatment of CINV and PONV

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Pages 575-585 | Published online: 09 Jan 2014

References

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  • •One of only two articles found in the authors' extensive literature research about pharmacoeconomic considerations concerning postoperative nausea and vomiting and thus highly relevant to this review. It contains a cost-effectiveness analysis comparing two different anesthetic models to avoid postoperative nausea and vomiting. One of these models uses an antiemetic prophylaxis with tropisetron and fortecortin.
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  • ••The only meta-analysis of tropisetron forthe prophylaxis of postoperative nausea and vomiting in the authors literature search
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  • •Covers work from a research group that concentrated on the efficacy of tropisetron for the prophylaxis and treatment of chemotherapy induced nausea and vomiting.
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  • ••Highly relevant to this review since itssubject is a cost—benefit analysis comparing odansetron, granisetron and tropisetron for the prevention of chemotherapy-induced nausea and vomiting.
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  • Trani& MR. A rational approach to the control of postoperative nausea and vomiting: evidence from systematic reviews. Part I. Efficacy and harm of antiemetic interventions and methodological issues. Acta. Anaesthesia" Land. 45,4-13 (2001).
  • •Gives an overview of the evidence from systematic reviews concerning the treatment and prevention of postoperative nausea and vomiting. They compare the efficacy and side effects of all available antiemetic agents found in different studies and recommend different concepts for the prophylaxis of postoperative nausea and vomiting.
  • Trani& MR. A rational approach to the control of postoperative nausea and vomiting: evidence from systematic reviews. Part II. Recommendations for prevention and treatment and a research agenda. Acta. Anaesthesia" Scand. 45,14-19 (2001).
  • •Gives an overview of the evidence from systematic reviews concerning the treatment and prevention of postoperative nausea and vomiting. They compare the efficacy and side effects of all available antiemetic agents found in different studies and recommend different concepts for the prophylaxis of postoperative nausea and vomiting.
  • Trani& MR, Phillips C, Reynolds DJM, McQuay HJ, Moore RA. Cost-effectiveness of ondansetron for postoperative nausea and vomiting. Anaesthesia 54,226-234 (1999).
  • •Second article that could be found on the subject of the cost-effectiveness of the 5-HT3 antagonist odansetron for the prophylaxis of post operative nausea and vomiting.

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