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Potential of glyburide to reduce intracerebral edema in brain metastases

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References

  • Eichler AF, Chung E, Kodack DP, et al. The biology of brain metastases – translation to new therapies. Nat Rev Clin Oncol 2001;8(6):344–56
  • Ortuzar W, Hanna N, Pennella E, et al. Brain metastases as the primary site of relapse in two randomized phase III pemetrexed trials in advanced non-small-cell lung cancer. Clin Lung Cancer 2012;13(1):24-30
  • Ryken TC, McDermott M, Robinson PD, et al. The role of steroids in the management of brain metastases: a systematic review and evidence-based clinical practice guideline. J Neurooncol 2010;96(1):103-14
  • Soffietti R, Cornu P, Delattre JY, et al. EFNS Guidelines on diagnosis and treatment of brain metastases: report of an EFNS Task Force. Eur J Neurol 2006;13(7):674-81
  • Vecht CJ, Hovestadt A, Verbiest HB, et al. Dose-effect relationship of dexamethasone on Karnofsky performance in metastatic brain tumors: a randomized study of doses of 4, 8, and 16 mg per day. Neurology 1994;44(4):675-80
  • Omuro AM, Delattre JY. What is the place of bevacizumab and irinotecan in the treatment of glioblastoma and other malignant gliomas? Curr Opin Neurol 2008;21(6):717-19
  • Simard JM, Sheth KN, Kimberly WT, et al. Glibenclamide in cerebral ischemia and stroke. Neurocrit Care 2013. [ Epub ahead of print]
  • Kurland DB, Tosun C, Pampori A, et al. Glibenclamide for the treatment of acute CNS injury. Pharmaceuticals 2013;6(10):1287-303
  • Simard JM, Chen M, Tarasov KV, et al. Newly expressed SUR1-regulated NC(Ca-ATP) channel mediates cerebral edema after ischemic stroke. Nat Med 2006;12(4):433-40
  • Simard JM, Geng Z, Woo SK, et al. Glibenclamide reduces inflammation, vasogenic edema, and caspase-3 activation after subarachnoid hemorrhage. J Cereb Blood Flow Metab 2009;29(2):317-30
  • Simard JM, Kilbourne M, Tsymbalyuk O, et al. Key role of sulfonylurea receptor 1 in progressive secondary hemorrhage after brain contusion. J Neurotrauma 2009;26(12):2257-67
  • Simard JM, Tsymbalyuk O, Ivanov A, et al. Endothelial sulfonylurea receptor 1-regulated NC Ca-ATP channels mediate progressive hemorrhagic necrosis following spinal cord injury. J Clin Invest 2007;117(8):2105-13
  • Silver FL, Fang J, Robertson AC, et al. Possible neuroprotective effects of sulfonylureas in diabetic patients with acute ischemic stroke. Abstracts from the 2009 International Stroke Conference. Stroke 2009;40:e516
  • Kunte H, Busch MA, Trostdorf K, et al. Hemorrhagic transformation of ischemic stroke in diabetics on sulfonylureas. Ann Neurol 2012;72(5):799-806
  • Thompson EM, Pishko GL, Muldoon LL, Neuwelt EA. Inhibition of SUR1 decreases the vascular permeability of cerebral metastases. Neoplasia 2013;15(5):535-43
  • Simard JM, Soo SK, Schwartzbauer GT, Gerzanich V. Sulfonylurea receptor 1 in central nervous system injury: a focused review. J Cereb Blood Flow Metab 2012;32(9):1699-717
  • Bryan J, Muñoz A, Zhang X, et al. ABCC8 and ABCC: ABC transporters that regulate K+ channels. Pflugers Arch 2007;453(5):703-18
  • Seino S. ATP-sensitive potassium channels: a model of heteromultimeric potassium channel/receptor assemblies. Annu Rev Physiol 1999;61:337-62
  • Yamada K, Inagaki N. Neuroprotection by KATP channels. J Mol Cell Cardiol 2005;38(6):945-9
  • Chen M, Dong Y, Simard JM. Functional coupling between sulfonylurea receptor type 1 and a nonselective cation channel in reactive astrocytes from adult rat brain. J Neurosci 2003;23(24):8568-77
  • Simard JM, Tarasov KV, Gerzanich V. Non-selective cation channels, transient receptor potential channels and ischemic stroke. Biochim Biophys Acta 2007;1772(8):947-57
  • Chen M, Simard JM. Cell swelling and a nonselective cation channel regulated by internal Ca2+ and ATP in native reactive astrocytes from adult rat brain. J Neurosci 2001;21(17):6512-21
  • Guinamard R, Sallé L, Simard C. The non-selective monovalent cationic channels TRPM4 and TRPM5. Adv Exp Med Biol 2011;704:147-71
  • Bano D, Nicotera P. Ca2+ signals and neuronal death in brain ischemia. Stroke 2007;38(2 suppl):674-6
  • Simard JM, Woo SK, Norenberg MD, et al. Brief suppression of Abcc8 prevents autodestruction of spinal cord after trauma. Sci Transl Med 2010;2(28):28ra29
  • Simard JM, Woo SK, Bhatta S, Gerzanich V. Drugs acting on SUR1 to treat CNS ischemia and trauma. Curr Opin Pharmacol 2008;8(1):42-9
  • Tomiyama Y, Brian JE Jr, Todd MM. Cerebral blood flow during hemodilution and hypoxia in rats: role of ATP-sensitive potassium channels. Stroke 1999;30(9):1942-7
  • Nedergaard M, Kraig RP, Tanabe J, Pulsinelli WA. Dynamics of interstitial and intracellular pH in evolving brain infarct. Am J Physiol 1991;260(3 pt 2):R581-8
  • Ortega FJ, Jolkkonen J, Mahy N, Rodríguez MJ. Glibenclamide enhances neurogenesis and improves long-term functional recovery after transient focal cerebral ischemia. J Cereb Blood Flow Metab 2012;33(3):356-64
  • Sullivan HC, Harik SI. ATP-sensitive potassium channels are not expressed in brain microvessels. Brain Res 1993;612(1–2):336-8
  • Mehta RI, Ivanova S, Tosun C, et al. Sulfonylurea receptor 1 expression in human cerebral infarcts. J Neuropathol Exp Neurol 2013;72(9):871-3
  • Woo SK, Kwon MS, Geng Z, et al. Sequential activation of hypoxia-inducible factor 1 and specificity protein 1 is required for hypoxia-induced transcriptional stimulation of Abcc8. J Cereb Blood Flow Metab 2012;32(3):525-36
  • Woo SK, Kwon MS, Ivanov A, et al. The sulfonylurea receptor 1 (Sur1)-transient receptor potential melastatin 4 (TRPM4) channel. J Biol Chem 2013;288(5):3655-67
  • Liss B, Roeper J. Molecular physiology of neuronal K-ATP channels. Mol Membr Biol 2001;18(2):117-27
  • Wali B, Ishrat T, Atif F, et al. Glibenclamide administration attenuates infarct volume, hemispheric swelling, and functional impairments following permanent focal cerebral ischemia in rats. Stroke Res Treat 2012;2012:460909
  • Simard JM, Tsymbalyuk N, Tsymbalyuk O, et al. Glibenclamide is superior to decompressive craniectomy in a rat model of malignant stroke. Stroke 2010;41(3):531-7
  • Ortega FJ, Gimeno-Bayon J, Espinosa-Parrilla JF, et al. ATP-dependent potassium channel blockade strengthens microglial neuroprotection after hypoxia-ischemia in rats. Exp Neurol 2012;235(1):282-96
  • Acarin L, González B, Castellano B. Neuronal, astroglial, and microglial expression after an excitotoxic lesion in the immature rate brain. Eur J NeuroSci 2000;12(10):3505-20
  • Kitamura Y, Takata K, Inden M, et al. Intracerebroventricular injection of microglia protects against focal brain ischemia. J Pharmacol Sci 2004;94(2):203-6
  • Gu W, Brännström T, Wester P. Cortical neurogenesis in adult rats after reversible photothrombotic stroke. J Cereb Blood Flow Metab 2000;20(8):1166-73
  • Kurland D, Hong C, Aarabi B, et al. Hemorrhagic progression of a contusion after traumatic brain injury: a review. J Neurotrauma 2012;29(1):19-31
  • Hackenberg K, Zweckberger K, Sakowitz O, et al. Glibenclamide reduces secondary brain damage after experimental traumatic brain injury. Presented at the 64th Annual Meeting of the German Society of Neurosurgery; 27 May 2013; Dusseldorf, Germany
  • Griffiths IR, Burns N, Crawford AR. Early vascular changes in the spinal grey matter following impact injury. Acta Neuropathol 1978;41(1):33-9
  • Popovich PG, Lemeshow S, Gensel JC, Tovar CA. Independent evaluation of the effects of glibenclamide on reducing progressive hemorrhagic necrosis after cervical spinal cord injury. Exp Neurol 2012;233(2):615-22
  • Aarnoudse-Moens CS, Weisglas-Kuperus N, van Goudoever JB, Oosterlaan J. Meta-analysis of neurobehavioral outcomes in very preterm and/or very low birth weight children. Pediatrics 2009;124(2):717-28
  • Tosun C, Koltz MT, Kurland DB, et al. The protective effect of glibenclamide in a model of hemorrhagic encephalopathy of prematurity. Brain Sci 2013;3(1):215-38
  • Turkbey B, Thomasson D, Pang Y, et al. The role of dynamic contrast-enhanced MRI in cancer treatment. Diagn Interv Radiol 2010;16(3):186-92
  • Bauer AT, Burgers HF, Rabie T, Marti HH. Matrix metallo-proteinase-9 mediates hypoxia-induced vascular leakage in the brain via tight junction rearrangement. J Cereb Blood Flow Metab 2010;30(4):837-48
  • Lai CH, Kuo KH, Leo JM. Critical role of actin in modulating BBB permeability. Brain Res Brain Res Rev 2005;50(1):7-13
  • Blum MS, Toninelli E, Anderson JM, et al. Cyto-skeletal rearrangement mediates human microvascular endothelial tight junction modulation by cytokines. Am J Physiol 1997;273(1 Pt 2):H286-94
  • Simard JM, Kahle KT, Gerzanich V. Molecular mechanisms of microvascular failure in central nervous system injury—synergistic roles of NKCC1 and SUR1/TRPM4. J Neurosurg 2010;113(3):622-9
  • Ghassemifar R, Lai CM, Rakoczy PE. VEGF differentially regulates transcription and translation of ZO-1α+ and ZO-1α– and mediates trans-epithelial resistance in cultured endothelial and epithelial cells. Cell Tissue Res 2006;323(1):117-25
  • Spanberger T, Berghoff AS, Dinhof C, et al. Extent of peritumoral brain edema correlates with prognosis, tumoral growth pattern, HIF1a expression and angiogenic activity in patients with single brain metastases. Clin Exp Metastasis 2013;30(4):357-68
  • Ningaraj NS, Rao MK, Black KL. Adenosine 5′-triphosphate-sensitive potassium channel-mediated blood-brain tumor barrier permeability increase in a rat brain tumor model. Cancer Res 2003;63(24):8899-911
  • Varallyay CG, Muldoon LL, Gahramanov S, et al. Dynamic MRI using iron oxide nanoparticles to assess early vascular effects of antiangiogenic versus corticosteroid treatment in a glioma model. J Cereb Blood Flow Metab 2009;29(4):853-60
  • US National Institutes of Health. Glyburide Advantage in Malignant Edema and Stroke Pilot (GAMES-PILOT). ClinicalTrials.gov summary. Available from: http://clinicaltrials.gov/show/NCT01268683 [Last accessed 2 October 2013]
  • Thomalla G, Hartmann F, Juettler E, et al. Prediction of malignant middle cerebral artery infarction by magnetic resonance imaging within 6 hours of symptom onset: a prospective multicenter observational study. Ann Neurol 2010;68(4):435-45
  • Mlynash M, Lansberg MG, De Silva DA, et al. Refining the definition of the malignant profile: insights from the DEFUSE-EPITHET pooled data set. Stroke 2011;42(5):1270-5
  • Rankin, J Cerebral vascular accidents in patients over the age of 60. II. Prognosis. Scott Med J 1957;2(5):200-15
  • Sanák D, Nosál’ V, Horák D, et al. Impact of diffusion-weighted MRI-measured initial cerebral infarction volume on clinical outcome in acute stroke patients with middle cerebral artery occlusion treated by thrombolysis. Neuroradiology 2006;48(9):632-9
  • US National Institutes of Health. Glyburide Advantage in Malignant Edema and Stroke – Remedy Pharmaceuticals (GAMES-RP). ClinicalTrials.gov summary. Available from: http://clinicaltrials.gov/show/NCT01794182 NLM [Last accessed on 2 October 2013]
  • US National Institutes of Health. Glyburide (RP-1127) for Traumatic Brain Injury (TBI). ClinicalTrials.gov summary. Available from: http://clinicaltrials.gov/show/NCT01454154 [Last accessed on 2 October 2013]
  • Lexicomp Online. Glyburide drug information. upToDate, Inc., Waltham, MA, USA; 2013. Available from: www.uptodate.com/contents/glyburide-drug-information?detectedLanguage=en&source=search_result&search=glyburide&selectedTitle=1%7E57&provider=noProvider [Last accessed on 2 October 2013]
  • US National Institutes of Health. Safety Study of RP-1127 (Glyburide for Injection) in Healthy Volunteers. ClinicalTrials.gov summary. Available from: http://clinicaltrials.gov/show/NCT01132703 [Last accessed on 2 October 2013]
  • US National Institutes of Health. Glyburide Healthy Volunteer Study. ClinicalTrials.gov summary. Available from: http://clinicaltrials.gov/ct2/show/record/NCT01716338 [Last accessed on 2 October 2013]
  • Mutalik S, Udupa N. Glibenclamide transdermal patches: physiochemical, pharmacodynamics, and pharmacokinetic evaluations. J Pharm Sci 2004;93(6):1577-94
  • St. John Sutton M, Rendell M, Dandona P, et al. A comparison of the effects of rosiglitazone and glyburide on cardiovascular function and glycemic control in patients with type 2 diabetes. Diabetes Care 2002;25(11):2058-64
  • Meinert CL, Knatterud GL, Prout TE, Klimt CR. A study of the effects of hypoglycemic agents on vascular complications in patients with adult-onset diabetes. II. Mortality results. Diabetes 1970;19(Suppl):789-830
  • Meyer G, Badenhoop K. Glucocorticoid-induced insulin resistance and diabetes mellitus. Receptor-, postreceptor mechanisms, local cortisol action, and new aspects of antidiabetic therapy [in German]. Med Klin 2003;98(5):266-70
  • Epocrates Online. DiaBeta, glyburide. Available from: https://online.epocrates.com/noFrame/showPage.do?method=drugs&MonographId=626 [Last accessed on 22 October 2013]
  • Epocrates Online. Dexamethasone. Available from: https://online.epocrates.com/noFrame/showPage.do?method=drugs&MonographId=189&ActiveSectionId=6 [Last accessed on 22 October 2013]
  • Giglio P, Gilbert MR. Cerebral radiation necrosis. Neurologist 2003;9(4):180-8
  • Glantz MJ, Burger PC, Friedman AH, et al. Treatment of radiation-induced nervous system injury with heparin and warfarin. Neurology 1994;44(11):2020-7
  • Rahmathulla G, Recinos PF, Valerio JE, et al. Laser interstitial thermal therapy for focal cerebral radiation necrosis: a case report. Stereotact Funct Neurosurg 2012;90(3):192-200
  • Williamson R, Kondziolka D, Kanaan H, et al. Adverse radiation effects after radiosurgery may benefit from oral vitamin e and pentoxifylline therapy: a pilot study. Stereotact Funct Neurosurg 2008;86(6):359-66
  • Deibert CP, Ahluwalia MS, Sheehan JP, et al. Bevacizumab for refractory adverse radiation effects after stereotactic radiosurgery. J Neurooncol 2013;115(2):217-23
  • Pan H-C, Sun M-H, Chen C-C, et al. Neuroimaging and quality-of-life outcomes in patients with brain metastasis and peritumoral edema who undergo Gamma Knife surgery. Neurosurg 2008;109(Suppl):90-8
  • Shuto T, Matsunaga S, Inomori S, Fujino H. Efficacy of gamma knife surgery for control of peritumoral edema associated with metastatic brain tumors. J Neurol Neurosurg Psychiatry 2008;79(9):1061-5
  • Edlow BL, Wu O, Singhal AB, et al. Glyburide reduces cytotoxic edema within the cerebral peduncles in acute ischemic stroke. Stroke 2013;44:ATP290
  • Kimberly WT, Battey TW, Pham L, et al. Glyburide is associated with attenuated vasogenic edema in stroke patients. Neurocrit Care 2013. [Epub ahead of print]

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