Natriuretic peptides and panic disorder: therapeutic prospects

References

• Samson WK. Natriuretic peptides. A family of hormones. Trends Endocrinol Metab. 3, 86–90 (1992).
   PubMedGoogle Scholar
• Imura H, Nakao K, Itoh H. The natriuretic peptide system in the brain: implications in the central control of cardiovascular and neuroendocrine functions. Front. Neumendocrinol 13, 217–249 (1992).
   Google Scholar
• •Excellent structured review that is still of considerable interest today.
   Google Scholar
• Kaneko T, Shirakami G, Nakao K et a/. C- type natriuretic peptide (CNP) is the major natriuretic peptide in human cerebrospinal fluid. Brain Res. 612, 104–109 (1993).
   Google Scholar
• Lowe DG, Kasai( I, Sparkes RS, Mohandas T, Goeddel DV Chromosomal distribution of the human natriuretic peptide receptor/ guanylyl cyclase gene family. Cenomics 8, 304–312 (1990).
   Google Scholar
• Wilcox JN, Augustine A, Goeddel DV, Lowe DG. Differential regional expression of three natriuretic peptide receptor genes within primate tissues. Mal Cell Biol. 11, 3454–3462 (1991).
   Google Scholar
• Herman JP, Dolgas CM, Marcinek R, Langub MC Jr. Expression and glucocorticoid regulation of natriuretic peptide clearance receptor (NPR-C) mRNA in rat brain and choroid plexus. .1. Chem. Neuroanat. 11, 257–265 (1996).
   Google Scholar
• Kukkonen P, Vuolteenaho 0, Ruskoaho H. Basal and volume expansion-stimulated plasma atrial natriuretic peptide concentrations and hemodynamics in conscious rats: effects of S CH39.370, an endopeptidase inhibitor and C-ANF-(4–23), a clearance receptor ligand. Endocrinology 130, 755–765 (1992).
   Google Scholar
• Yandle TG, Richards AM, Nicholls MG, Cuneo R, Espkner EA, Livesey JH. Metabolic clearance rate and plasma life of a-human atrial natriuretic peptide in man. Life Sci. 38, 1827–1833 (1986).
   PubMed Web of Science ®Google Scholar
• Hunt PJ, Richards AM, Espiner EA, Nicholls MG, Yandle TG. Bioactivity and metabolism of C-type natriuretic peptide in normal man. J. Clin. Endocrinol. Metab. 78, 1428–1435 (1994).
   Google Scholar
• Koller KH, Lowe DG, Bennett GL et al Selective activation of the B natriuretic peptide receptor by the C-type natriuretic peptide (CNP). Science 252,120–123 (1991).
   PubMed Web of Science ®Google Scholar
• Lopez MJ, Gathers DL, Kuhn M. The guanyl cyclase-deficient mouse defmes differential pathways of natriuretic peptide signaling. Biol. Chem. 272, 23064–23068 (1997).
   Google Scholar
• Langub MC, Watson RE, Herman JP. Distribution of natriuretic peptide precursor mRNAs in the rat brain. J. Comp. Neumlogy356, 183–199 (1995b).
   Google Scholar
• Langub MC, Dolgas CM, Watson RE, Herman JR The C-type natriuretic peptide receptor is the predominant natriuretic peptide receptor mRNA expressed in rat hypothalamus. I Neuroendocrinol 7, 305–309 (1995a).
   PubMedGoogle Scholar
• Sumners C, Tang W Atrial natriuretic peptide receptor subtypes in rat neuronaland astrocyte glial cultures. Am. J. Physiol 262, C1134—C1143 (1992).
   Google Scholar
• Kurihara M, Saavedra JM, Shigematsu K. Localization and characterization of atrial natriuretic peptide binding sites in discrete areas of rat brain and pituitary gland by quantitative autoradiography. Brain Res. 408,31–39 (1987).
   Google Scholar
• Yeung VTF, Lai CK, Cockram CS eta]. Atrial natriuretic peptide in the central nervous system. Neuroendocrinology53, 18–24 (1991).
   Google Scholar
• Holsboer E The rationale for corticotrophin-releasing hormone receptor (CRII-R) antagonists to treat depressionand anxiety. I PTchiatry Res. 33,181–214 (1999).
   PubMedGoogle Scholar
• Arborelius L, Owens MJ, Plotsky PM, Nemeroff CB. The role of corticotropin-releasing factor in depression and anxiety disorders. Endocrinol 160,1–12 (1999).
   Web of Science ®Google Scholar
• Liebsch GR, Landgraf R, Gerstberger R et al Chronic infusion of a CRTI-1 receptorantisense oligodeoxynucleotide into the central nucleus of the amygdala reduced anxiety-related behaviour in socially defeated rats. Reg. Peptides 59,229–239 (1995).
   Google Scholar
• Timpl P, Spanagel R, Sillaber let al Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1. Nat. Gene. 19,162-166 (1998).
   Google Scholar
• Takao T, Hashimoto K, Ota Z. Effect of atrial natriuretic peptide on acetylcholine-induced release of corticotropin-releasing factor from rat hypothalamus in vitro. Life Sci. 42,1199–1203 (1988).
   Google Scholar
• Ibanez-Santos J, Tsagarakis S, Rees LH, Besser GM, Grossman A. Atrial natriuretic peptides inhibit the release of corticotropin-releasing factor-41 from the rat hypothalamus in vitro. J. Endocrinol 126, 223–228 (1990).
   Google Scholar
• Antoni FA, Hunter EFM, Lowry PJ, Noble JM, Seckl JR. Atriopeptin: an endogenous corticotropin-release inhibiting hormone. Endocrinol 130,1753–1755 (1992).
   PubMed Web of Science ®Google Scholar
• Vesely DL, San Miguel GI, Hassan I, Schocken DD. Atrial natriuretic hormone, vessel dilator, long-acting natriureitc hormone and kaliureitc hormone decrease the circulating concentrations of CRH, corticotropin and cortisol. j Gun. Endocrinol Metab. 86,4244–4249 (2001).
   PubMedGoogle Scholar
• Jessop DS. Central nonglucocorticoid inhibitors of the hypothalamo-pituitary-adrenal axis. Endocrinol 160,169–180 (1999).
   Google Scholar
• Haug C, Grunt M, Schmid S eta]. Effect of corticotropin releasing factor on atrial natiruretic peptide release from the isolated perfused rat heart. Arzneimitte1forschung44, 579–582 (1994).
   Google Scholar
• Tojo K, Sato S, Tokudome G eta]. Stimulation by corticotropin-releasing factor of atrial natriuretic peptide and brain natriuretic peptide secretions from cultured neonatal rat cardiomyocytes. Biochem. Biophys. Res. Commun. 225,340–346 (1996).
   Google Scholar
• Colao A, Pivonello R, Ferone D eta]. Effect of corticotrophin-releasing hormone on arginine vasopressin and atrial natriuretic factor in patients with Cushing's disease. Gun. Endocrinol 49,77–84 (1998).
   Google Scholar
• Lim AT, Sheward WJ, Copolov D, Windmill D, Fink G. Atrial natriuretic factor is released into hypophysial portal blood: direct evidence that atrial natriuretic factor may be a neurohormone involved in hypothalamic pituitary control. J. Neuroendocrinol 2,15–17 (1990).
   Google Scholar
• King MS, Baertschi AJ. Physiological concentrations of atrial natriuretic factors with intact N-terminal sequences inhibit corticotropin-releasing factor-stimulated adrenocorticotropin secretion from cultured anterior pituitary cells. Endocrinology124, 286–292 (1989).
   PubMedGoogle Scholar
• Dayanithi G, Antoni FA. Atriopeptins are potent inhibitors of ACTH secretion by rat anterior pituitary cells in vitro involvement of the atrial natriuretic factor receptor domain of membrane-bound guanylyl cyclase. I Endocrinol 125,39–44 (1990).
   Google Scholar
• Naruse M, Obana K, Naruse K eta]. Atrial natriuretic peptide inhibits cortisol secretion as well as aldosterone secretion in vitro from human adrenal tissue. J. Gun. Endocrinol Metab. 64,10–16 (1987).
   Google Scholar
• Kellner M, Wiedemann K, Holsboer Atrial natriuretic factor inhibits the CRTI-stimulated secretion of ACTH and cortisol in man. Life Sci. 50,1835–1842 (1992).
   PubMed Web of Science ®Google Scholar
• Gardner DG, Gertz BJ, Deschepper CF, Kim DY. Gene for the rat atrial natriuretic peptide is regulated by glucccorticoids in sdtmj Gun. Invest 89,1275–1281 (1988).
   Google Scholar
• Fink G, Dow RC, Casley D eta]. Atrial natriuretic peptide is a physiological inhibitor of ACTH release: evidence from immunoneutralization in vivo. J. Endocrinol 131, R9—R12 (1991).
   Google Scholar
• Ur E, Faria M, Tsagarakis S, Anderson JV, Besser GM, Grossmann A. Atrial natriuretic peptide in physiological doses does not inhibit the ACTH or cortisol response to corticotrophin-releasing hormone-41 in normal human subjects. Endocrinol 131,163–167 (1991).
   Google Scholar
• Wittert GA, Espiner EA, Richards AM, Donald RA, Livesey JH, Yandle TG. Atrial natriuretic factor reduces vasopressin and angiotensin II but not the ACTH response to acute hypoglycaemic stress in normal men. Gun. Endocrinol 38,183–189 (1993).
   Google Scholar
• Wiedemann K, Herzog L, Kellner M. Atrial natriuretic hormone inhibits corticotropin-releasing hormone-induced prolactin release in man. J. PTchiat. Res. 29,51–58 (1995).
   Google Scholar
• Kellner M, Herzog L, Holsboer F, Wiedemann K. Circadian changes in the sensitivity of the corticotropin-releasing hormone-stimulated HPA system after arginine vasopressin and atrial natriuretic hormone in human male controls. Psychoneuroendocrinology20,515–524 (1995).
   PubMedGoogle Scholar
• Bierwolf C, Burgemeister A, Luthke K, Born J, Fehm HL. Influence of exogenous atrial natriuretic peptide on the pituitary—adrenal response to corticotropin-releasing hormone and vasopressin in healthy men. J. Gun. Endocrinol Metab. 83,1151–1157 (1998).
   Google Scholar
• Ströhle A, Kellner M, Holsboer F, Wiedemann K. Atrial natriuretic hormone decreases endocrine response to a combined dexamethasone—corticotropin-releasing hormone test. Biol. Psychiatry 43, 371–375 (1998).
   Google Scholar
• Charles CJ, Espiner EA, Richards AM, Donald RA. Central c-type natriuretic peptide augments the hormone response to hemorrhage in conscious sheep. Peptides16, 129–132 (1995).
   PubMedGoogle Scholar
• Kellner M, Diehl I, Knaudt K, Schille C, Jahn H, Wiedemann K. C-type natriuretic peptide exerts stimulatory effects on the corticotropin-releasing hormone-induced secretion of hormones in normal man. Eur. Endocrinol 136,388–393 (1997).
   Google Scholar
• Hollander E, Liebowitz MR, Gorman JM, Cohen B, Fyer A, Klein DE Cortisol and sodium lactate-induced panic. Arch. Gen. Psychiatry 46, 135–140 (1989).
   PubMedGoogle Scholar
• Targum SD. Cortisol response during different anxiogenic challenges in panic disorder patients. PTchoneuroendocrinology 17,453–458 (1992).
   PubMed Web of Science ®Google Scholar
• Cameron OG, Lee MA, Curtis GC, McCann DS. Endocrine and physiological changes during 'spontaneous' panic attacks. PTchoneumendocrinology12,321–331 (1987).
   PubMed Web of Science ®Google Scholar
• Liebowitz ML, Gorman JM, Fyer AJ et al. Lactate provocation of panic attacks: II: biochemical and physiological findings. Arch. Gen. Psychiatry 42, 709–719 (1985).
   PubMed Web of Science ®Google Scholar
• Kellner M, Herzog L, Yassouridis A, Holsboer F, Wiedemann K. Possible role of atrial natriuretic hormone in pituitary—adrenocortical unresponsiveness in lactate-induced panic. Am. j fiychiatry152, 1365–1367 (1995).
   Google Scholar
• •First report to investigate putative role of atrial natriuretic peptide in the hypothalamic—pituitary—adrenocortical paradox in panic.
   Google Scholar
• Kellner M, Knaudt K, Jahn H, Holsboer F, Wiedemann K. Atrial natriuretic hormone in lactate-induced panic attacks: mode of release and endocrine and pathophysiological consequences. Psychiatry Res. 32, 37–48 (1998).
   Google Scholar
• Kellner M, Wiedemann K. Nonresponse of adrenocorticotropic hormone in first-ever lactate-induced panic attacks in healthy volunteers. Arch. Gen. Psychiaby55, 85–86 (1998).
   PubMedGoogle Scholar
• Klein DE False suffociation alarms, spontaneous panics and related conditions: an integrative hypothesis. Awl?. Gen. PTchiatry50, 306–317 (1993).
   PubMedGoogle Scholar
• Roy-Byrne PP, Uhda TVV, Post RM, Gallucci W Chrousos GP, Gold PW. The corticotropin-releasing hormone stimulation test in patients with panic disorder. Am. j PTchiatry143, (896–899) 1986.
   Google Scholar
• Holsboer F, von Bardeleben U, Buller R, Heuser I, Steiger A. Stimulation response to corticotropin-releasing hormone (CRII) inpatients with depression, alcoholism and panic disorder. Harm. Metab. Res. 19, 80–88 (1987).
   PubMedGoogle Scholar
• Schreiber W, Lauer CJ, Krumrey K, Holsboer F, Krieg JC. Dysregulation of the hypothalamic—pituitary—adrenocortical system in panic disorder. Neuropsychopharmacology (1997).
   Google Scholar
• Seier FE, Kellner M, Yassouridis A, Heese R, Strian F, Wiedemann K. Autonomic reactivity and hormonal secretion in lactate-induced panic attacks. Am. Physiol 272, H2630—H2638 (1997).
   Google Scholar
• Butler GC, Senn BL, Floras JS. Influence of atrial natriuretic factor on heart rate variability in normal men. Am. j Physiol267, H500—H505 (1994).
   Google Scholar
• Harro J, Vasar E, Bradwejn J. CCK in animal and human research on anxiety. 77PS14, 244–249 (1993).
   Google Scholar
• Wiedemann K, Jahn H, Yassouridis A, Kellner M. Anxiolyticlike effects of atrial natriuretic peptide on cholecystokinin tetrapeptide-induced panic attacks: preliminary findings. Arch. Gen. Psychiatry 58, 371–377 (2001).
   PubMed Web of Science ®Google Scholar
• ••First report on psychotropic effects ofANP in humans.
   Google Scholar
• Kellner M, Wiedemann K. Atrial natriuretic hormone responses to clonidine in patients with panic disorder and in healthy control subjects. Eur j Enclocrinol 137, 84–85 (1997).
   PubMedGoogle Scholar
• Poggioli R, Vergoni AV, Rasori E, Marrama D, Bertolini A. Behavioral effects of atriopeptin in rats. Neuropepticles 22, 149–154 (1992).
   Google Scholar
• Bidzseranova A, Gueron J, Toth G, Penke B, Varga J, Teledgy G. Behavioral effects of atrial natriuretic and brain natriuretic peptides in rats. Neurorep. 3, 283–285 (1992).
   PubMedGoogle Scholar
• Bhattacharya SK, Chakrabarti A, Sandler M, Glover V. Anxiolytic activity of intraventricularly administered atrial natriuretic peptide in the rat. Neuropsychopharmacology15, 199–206 (1996).
   PubMedGoogle Scholar
• Bird') É, Toth G, Telegdy G. Involvement of neurotransmitters in the 'anxiolytic-like' action of atrial natriuretic peptide in rats. Neuopepticles 29, 215–220 (1995).
   Google Scholar
• Ströhle A, Jahn H, Montkowski A et al. Central and peripheral administration of atriopeptin is anxiolytic in rats. Neuroenclocrinology 65, 210–215 (1997).
   PubMed Web of Science ®Google Scholar
• Montkowski A, Jahn H, Ströhle A, Poettig M, Holsboer F, Wiedemann K. C-type natriuretic peptide exerts effects opposing those of atrial natriuretic peptide on anxiety-related behaviour in rats. Brain Res. 792, 358–360 (1998).
   Google Scholar
• Samson WK, Scala KD, Huang FLS. CNP-22 stimulates, rather than inhibits, water drinking in the rat: evidence for an unique biological action of the C-type natriuretic peptides. Brain Res. 568, 285–288 (1992).
   Google Scholar
• Trachte GJ, Kanwal S, Elmquist BJ, Ziegler RJ. C-type natriuretic peptide neuromodulates via Clearance' receptors. Am. Physiol 268, C978—C984 (1995).
   Google Scholar
• Jahn H, Montkowski A, Knaudt K eta], a- helical-corticotropin-releasing hormone reverses anxiogenic effects of C-type natriuretic peptide in rats. Brain Res. 893, 21–28 (2001).
   PubMedGoogle Scholar
• Ströhle A, Kellner M, Holsboer F, Wiedemann K. Anxiolytic activity of atrial natriuretic peptide (ANP) in patients with panic disorder. Am j fiychiatry158, 1514–1516 (2001).
   Google Scholar
• Biro É, Sarnyai Z, Penke B, Szabo B, Telegdy G. Role of endogenous corticotropin-releasing factor in mediation of neuroendocrine and behavioral responses to cholecystokinin octapeptide sulfate ester in rats. Ainmencloainology57, 340–345 (1995).
   Google Scholar
• Kellner M, Yassouridis A, Hua Y, Wendrich M, Jahn H, Wiedemann K. Intravenous C-type natriuretic peptide augments behavioral and endocrine effects of choleystokinin tetrapeptide in healthy man. Psych. Res. 36, 1–6 (2002).
   Google Scholar
• ••First report on psychotropic effects of CNP in man.
   Google Scholar