Treatment of depressive symptoms with quetiapine

References

• Kasper S, Muller-Spahn E Review of quetiapine and its clinical applications in schizophrenia. Expert Opin. Pharmacother. 1,783–801 (2000).
   PubMedGoogle Scholar
• •Recent review on quetiapine in schizophrenia.
   Google Scholar
• Martin RL, Cloninger CR, Guze SB, Clayton PJ. Frequency and differential diagnosis of depressive syndromes in schizophrenia.j Gun. fisychiatry 46, 9–13 (1985).
   Google Scholar
• Wassink TH, Flaum M, Nopoulos P, Andreasen NC. Prevalence of depressive symptoms early in the course of schizophrenia. A117. I fiychiatry156,315–316 (1999).
   Google Scholar
• Keck PE Jr, Strakowski SM, McElroy SL The efficacy of atypical antipsychotics in the treatment of depressive symptoms, hostility and suicidality in patients with schizophrenia Gun. Psychiatry61\(Supp1. 3), 4–9 (2000).
   Google Scholar
• Regier DA, Farmer ME, Rae DS eta]. Comorbidity of mental disorders with alcohol and other drug abuse. Results from the Epidemiologic Catchment Area (ECA) Study. JAIVIA 264,2511–2518 (1990).
   Google Scholar
• Koreen AR, Sins SG, Chakos M, Alvir J, Mayerhoff D, Lieberman J. Depression in first-episode schizophrenia. Am. Psychiatry 150, 1643–1648 (1993).
   PubMed Web of Science ®Google Scholar
• Roy A, Thompson R, Kennedy S. Depression in chronic schizophrenia. BE Psychiatry 142, 465–470 (1983).
   Google Scholar
• AstraZeneca Pharmaceuticals. Data on file.
   Google Scholar
• Tollefson GD, Sanger TM, Lu Y, Thieme ME. Depressive signs and symptoms in schizophrenia: a prospective blinded trial of olanzapine and haloperidol. Arch. Gen. Psychiatry 55, 250–258 (1998).
   PubMed Web of Science ®Google Scholar
• Ghaemi SN. New treatments for bipolar disorder: the role of atypical neuroleptic agents. j Gun. Ptychiatry61\(Suppl. 14), 33–42 (2000). itSaller CF, Salama AT. Seroquel: biochemical profile of a potential atypical antipsychotic. fiychopharmacology (Ben). 112, 285–292 (1993).
   Google Scholar
• Small JG, Hirsch SR, Arvanitis LA, Miller BG, Link CG. Quetiapine in patients with schizophrenia. A high- and low-dose double-blind comparison with placebo. Seroquel Study Group. Arch. Gem fiychiatry54, 549–557 (1997).
   Google Scholar
• ••Clinical trial that assessed efficacy andsafety of quetiapine in schizophrenia patients. This included the effect of quetiapine on depressive symptoms.
   Google Scholar
• Sajatovic M, Brescan DW, Perez DE et al. Quetiapine alone and added to a mood stabilizer for serious mood disorders.j Gun. Psychiatry 62, 728–732 (2001) .
   Google Scholar
• •This study examined the effect of quetiapine on depressive symptoms in patients with mood disorders.
   Google Scholar
• Arvanitis LA, Miller BG. Multiple fixed doses of Seroquel (quetiapine) in patients with acute exacerbation of schizophrenia: a comparison with haloperidol and placebo. The Seroquel Trial 13 Study Group. Biol. Psychiatry 42, 233–246 (1997).
   Google Scholar
• •• Double-blind, randomized, controlled trial that assessed efficacy and safety of quetiapine in schizophrenia patients. This included the effect of quetiapine on depressive symptoms.
   Google Scholar
• Mullen J, Jibson MD, Sweitzer D. A comparison of the relative safety, efficacy and tolerability of quetiapine and risperidone in outpatients with schizophrenia and other psychotic disorders: the quetiapine experience with safety and tolerability (QUEST) study. Clirz Ther. 23, 1839–1854 (2001).
   PubMed Web of Science ®Google Scholar
• •Compares the efficacy and safety of quetiapine and risperidone in patients with schizophrenia and includes an assessment of the effects of these drugs on depressive symptoms.
   Google Scholar
• Tauscher-Wisniewski S, Kapur S, Tauscher J etal Quetiapine: an effective antipsychotic in first-episode schizophrenia despite only transiently high dopamine-2 receptor blockade. j Gun. Psychiatry 63, 992–997 (2002).
   Google Scholar
• Buckley PE Broad therapeutic uses of atypical antipsychotic medications. Biol. Ptychiatry50, 912–924 (2001).
   Google Scholar
• Keck PE Jr. What makes a drug a primary mood stabilizer? Mal Psychology 7(Suppl. 1), S8—S14 (2002).
   Google Scholar
• Khouzam HR. Treatment of depressive mood in schizophrenia with the atypical antipsychotic quetiapine. Depress. Anxiety 11, 80–82 (2000).
   PubMed Web of Science ®Google Scholar
• •Discusses two cases of patients with schizophrenia whose depressive symptoms improved with quetiapine treatment.
   Google Scholar
• Emsley RA, Raniwalla J, Bailey PJ, Jones AM. A comparison of the effects of quetiapine (Seroquel') and haloperidol in schizophrenic patients with a history of and a demonstrated, partial response to conventional antipsychotic treatment. PRIZE Study Group. Int. Gun. Psychopharmacol 15, 121–131 (2000).
   PubMed Web of Science ®Google Scholar
• •The first international, randomized, double-blind study to compare quetiapine with haloperidol in patients with schizophrenia (includes data on their effects on depressive symptoms).
   Google Scholar
• Irmansyah, Jones AM, Whiteford JL, Altman C. Switching patients to quetiapine improves depressive symptoms in schizophrenia. Int. .1. Aiumpsychopharmacol 5 (Suppl. 1), 122 (2002).
   Google Scholar
• Sajatovic M, Mullen JA, Sweitzer DE. Efficacy of quetiapine and risperidone against depressive symptoms in outpatients with psychosis. j Clin. Psychiatry 63, 1156–1163 (2002).
   Google Scholar
• ••Directly compares the efficacy of quetiapine and risperidone on depressive symptoms in patients with psychosis and one of several DSM-1V diagnoses, induding independent data on bipolar disorder
   Google Scholar
• Brown ES, Nejtek VA, Perantie DC, Bobadilla L. Quetiapine in patients with bipolar disorder and cocaine dependence. Bipolar Disarl 4, 406–411 (2002).
   PubMed Web of Science ®Google Scholar
• •First study to address treatment of patients with bipolar disorder and comorbid substance (cocaine) dependence with quetiapine.
   Google Scholar
• Goodwin FK, Jamison KR. Manic- Depressive Illness. Oxford University Press, NY, USA (1990).
   Google Scholar
• Chisholm K, Dennehy E, Suppes T Clinical response to quetiapine add-on for treatment of refractory bipolar disorder. Paper presented at: 4th International Conference on Bipolar Disarler, Pittsburgh, PA, USA (2001).
   Google Scholar
• Zarate CA Jr, Rothschild A, Fletcher KE, Madrid A, Zapatel J. Clinical predictors of acute response with quetiapine in psychotic mood disorders. Cl/n. Ptychiatry61, 185–189 (2000).
   Google Scholar
• Keck PE Jr, Syllabus and proceedings summary of the APA meeting. New Orleans, LA, USA, May 5–10, 93 (Abstract 34E) (2001).
   Google Scholar
• Sachs G, Mullen JA, Devine NA, Sweitzer DE. Quetiapine versus placebo as adjunct to mood stabilizer for the treatment of acute mania. Bipolar Disonl. 4\(Suppl. 1), 133 (2002).
   Google Scholar
• ••First report of a large, randomized, double-blind clinical trial of adjunctive treatment with quetiapine in patients with bipolar disorder. Includes assessment of the effect of quetiapine on depressive symptoms.
   Google Scholar
• Geddes J, Freemantle N, Harrison P, Bebbington P Atypical antipsychotics in the treatment of schizophrenia: systematic overview and meta-regression analysis. Br. Merl 321, 1371–1376 (2000).
   PubMed Web of Science ®Google Scholar