The effect of infections and vaccinations on stroke risk

References

• Khaw KT. Epidemiology of stroke. J. Neurol. Neurosurg. Psych. 61, 333–338 (1996).
   PubMed Web of Science ®Google Scholar
• Hacke W, Brott T, Caplan L et al. Thrombolysis in acute ischemic stroke: controlled trials and clinical experience. Neurology 53, S3–S14 (1999).
   PubMed Web of Science ®Google Scholar
• Grau AJ, Weimar C, Buggle F et al. Risk factors, outcome, and treatment in subtypes of ischemic stroke: the German stroke data bank. Stroke 32, 2559–2566 (2001).
   PubMed Web of Science ®Google Scholar
• Lawes CM, Bennett DA, Feigin VL, Rodgers A. Blood pressure and stroke: an overview of published reviews. Stroke 35, 1024–1033 (2004).
   Web of Science ®Google Scholar
• Olsson SB, Halperin JL. Prevention of stroke in patients with atrial fibrillation. Semin. Vasc. Med. 5, 285–292 (2005).
   PubMedGoogle Scholar
• Amarenco P. Effect of statins in stroke prevention. Curr. Opin. Lipidol. 16, 614–618 (2005).
   PubMed Web of Science ®Google Scholar
• Gorelick PB. Stroke prevention therapy beyond antithrombotics: unifying mechanisms in ischemic stroke pathogenesis and implications for therapy: an invited review. Stroke 33, 862–875 (2002).
   PubMed Web of Science ®Google Scholar
• Lindsberg P, Grau AJ. Inflammation and infections as risk factors for ischemic stroke. Stroke 34, 2518–2532 (2003).
   PubMed Web of Science ®Google Scholar
• Smeeth L, Thomas SL, Hall AJ, Hubbard R, Farrington P, Vallance P. Risk of myocardial infarction and stroke after acute infection and vaccination. N. Engl. J. Med. 351, 2611–2618 (2004).
   PubMed Web of Science ®Google Scholar
• Chiu B. Multiple infections in carotid atherosclerotic plaques. Am. Heart J. 138, S534–S546 (1999).
   PubMed Web of Science ®Google Scholar
• Fiehn NE, Larsen T, Christiansen N, Holmstrup P, Schroeder TV. Identification of periodontal pathogens in atherosclerotic vessels. J. Periodontol. 76, 731–736 (2005).
   PubMed Web of Science ®Google Scholar
• Desvarieux M, Demmer RT, Rundek T et al. Relationship between periodontal disease, tooth loss, and carotid artery plaque: the oral Infections and Vascular Disease Epidemiology Study (INVEST). Stroke 34, 2120–2125 (2003).
   PubMed Web of Science ®Google Scholar
• Desvarieux M, Schwahn C, Volzke H et al. Gender differences in the relationship between periodontal disease, tooth loss, and atherosclerosis. Stroke 35, 2029–2035 (2004).
   PubMed Web of Science ®Google Scholar
• Grau AJ, Becher H, Ziegler CM et al. Periodontal disease as a risk factor for ischemic stroke. Stroke 35, 496–501 (2004).
   PubMed Web of Science ®Google Scholar
• Pussinen PJ, Alfthan G, Rissanen H, Reunanen A, Asikainen S, Knekt P. Antibodies to periodontal pathogens and stroke risk. Stroke 35, 2020–2023 (2004).
   PubMed Web of Science ®Google Scholar
• Engebretson SP, Lamster IB, Elkind MS et al. Radiographic measures of chronic periodontitis and carotid artery plaque. Stroke 36, 561–566 (2005).
   PubMed Web of Science ®Google Scholar
• Greenwell H, Bissada NF. Emerging concepts in periodontal therapy. Drugs 62, 2581–2587 (2002).
   PubMed Web of Science ®Google Scholar
• Grayston JT. Background and current knowledge of Chlamydia pneumoniae and atherosclerosis. J. Infect. Dis. 181, S402–S410 (2000).
   PubMed Web of Science ®Google Scholar
• Apfalter P, Barousch W, Nehr M, Willinger B, Rotter M, Hirschl AM. No evidence of involvement of Chlamydia pneumoniae in severe cerebrovascular atherosclerosis by means of quantitative real-time polymerase chain reaction. Stroke 35, 2024–2028 (2004).
   PubMed Web of Science ®Google Scholar
• Johnston SC, Messina LM, Browner WS, Lawton MT, Morris C, Dean D. C-reactive protein levels and viable Chlamydia pneumoniae in carotid artery atherosclerosis. Stroke 32, 2748–2752 (2001).
   PubMed Web of Science ®Google Scholar
• Vainas T, Kurvers AJM, Mess WH et al. Chlamydia pneumoniae serology is associated with thrombosis-related but not with plaque-related microembolization during carotid endarterectomy. Stroke 33, 1249–1254 (2002).
   PubMed Web of Science ®Google Scholar
• Johnsen SP, Overvad K, Ostergaard L, Tjonneland A, Husted SE, Sorensen HT. Chlamydia pneumoniae seropositivity and risk of ischemic stroke: a nested case-control study. Eur. J. Epidemiol. 20, 59–65 (2005).
   PubMed Web of Science ®Google Scholar
• LaBiche R, Koziol D, Quinn TC et al. Presence of Chlamydia pneumoniae in human symptomatic and asymptomatic carotid atherosclerotic plaque. Stroke 32, 855–860 (2001).
   PubMed Web of Science ®Google Scholar
• Etminan M, Carleton B, Delaney JA, Padwal R. Macrolide therapy for Chlamydia pneumoniae in the secondary prevention of coronary artery disease: a meta-analysis of randomized controlled trials. Pharmacotherapy 24, 338–343 (2004).
   PubMed Web of Science ®Google Scholar
• O´Connor CM, Dunne MW, Pfeffer MA et al. Investigators in the WIZARD study. Azithromycin for the secondary prevention of coronary heart disease events: the WIZARD study: a randomized controlled trial. JAMA 290, 1459–1466 (2003).
   PubMed Web of Science ®Google Scholar
• Grayston JT, Kronmal RA, Jackson LA et al. ACES Investigators. Azithromycin for the secondary prevention of coronary events. N. Engl. J. Med. 352, 1637–1645 (2005).
   PubMed Web of Science ®Google Scholar
• Sander D, Winbeck K, Klingelhöfer J, Etgen T, Conrad B. Progression of early carotid atherosclerosis is only temporarily reduced after antibiotic treatment of Chlamydia pneumoniae seropositivity. Circulation 109, 1010–1015 (2004).
   PubMed Web of Science ®Google Scholar
• Gieffers J, Fullgraf H, Jahn J et al. Chlamydia pneumoniae infection in circulating human monocytes is refractory to antibiotic tretament. Circulation 103, 351–356 (2001).
   PubMed Web of Science ®Google Scholar
• Sawayama Y, Ariyama I, Hamada M et al. Association between chronic Helicobacter pylori infection and acute ischemic stroke: Fukuoka Harasanshin Atherosclerosis Trial (FHAT). Atherosclerosis 178, 303–309 (2005).
   PubMed Web of Science ®Google Scholar
• Pietroiusti A, Diomedi M, Silvestrini M et al. Cytotoxin-associated gene-A-positive Helicobacter pylori strains are associated with atherosclerotic stroke. Circulation 106, 580–584 (2002).
   PubMed Web of Science ®Google Scholar
• Preusch MR, Grau AJ, Buggle F et al. Association between cerebral ischaemia and cytotoxin-associated gene-A-bearing strains of Helicobacter pylori. Stroke 35, 1800–1804 (2004).
   PubMed Web of Science ®Google Scholar
• Diomedi M, Pietroiusti A, Silvestrini M et al. CagA-positive Helicobacter pylori strains may influence the natural history of atherosclerotic stroke. Neurology 63, 800–804 (2004).
   PubMed Web of Science ®Google Scholar
• Cremonini F, Gabrielli M, Gasbarrini G et al. The relationship between chronic H. pylori infection, CagA seropositivity and stroke: meta-analysis. Atherosclerosis 173, 253–259 (2004).
   PubMed Web of Science ®Google Scholar
• Ameriso SF, Fridman EA, Leiguarda RC, Sevlever GE. Detection of Helicobacter pylori in human carotid atherosclerotic plaques. Stroke 32, 385–391 (2001).
   PubMed Web of Science ®Google Scholar
• Franceschi F, Sepulveda AR, Gasbarrini A et al. Cross-reactivity of antiCagA antibodies with vascular wall antigens: possible pathogenic link between Helicobacter pylori infection and atherosclerosis. Circulation 106, 430–434 (2002).
   PubMed Web of Science ®Google Scholar
• Espinola-Klein C, Rupprecht HJ, Blankenberg S et al. Impact of infectious burden on extent and long-term prognosis of atherosclerosis. Circulation 105, 15–21 (2002).
   PubMed Web of Science ®Google Scholar
• Kiechl S, Egger G, Mayr M et al. Chronic infections and the risk of carotid atherosclerosis. Prospective results from a large population study. Circulation 103, 1064–1070 (2001).
   PubMed Web of Science ®Google Scholar
• Ngeh J, Goodbourn C. Chlamydia pneumoniae , Mycoplasma pneumoniae, and Legionella pneumophila in elderly patients with stroke (C-PEPS, M-PEPS, L-PEPS): a case-control study on the infectious burden of atypical respiratory pathogens in elderly patients with acute cerebrovascular disease. Stroke 36, 259–265 (2005).
   PubMed Web of Science ®Google Scholar
• Ross R. Atherosclerosis – an inflammatory disease. N. Engl. J. Med. 340, 115–126 (1999).
   PubMed Web of Science ®Google Scholar
• Grau AJ, Boddy AW, Dukovic DA et al. The leukocyte count as an independent predictor of recurrent ischemic events. Stroke 35, 1137–1142 (2004).
   Google Scholar
• Napoli M, Papa F. Inflammation, hemostatic markers, and antithrombotic agents in relation to long-term risk of new cardiovascular events in first-ever ischemic stroke patients. Stroke 33, 1763–1771 (2002).
   PubMed Web of Science ®Google Scholar
• Ridker PM, Rifai N, Clearfield M et al. Measurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events. N. Engl. J. Med. 344, 1959–1965 (2001).
   PubMed Web of Science ®Google Scholar
• Nicholson KG, Wood JM, Zambon M. Influenza. N. Engl. J. Med. 362, 1733–1745 (2003).
   Google Scholar
• Nichol KL, Nordin J, Mullooly J, Lask R, Fillbrandt K, Iwane M. Influenza vaccination and reduction in hospitalizations for cardiac disease and stroke among the elderly. N. Engl. J. Med. 348, 1322–1332 (2003).
   PubMed Web of Science ®Google Scholar
• Lavallée P, Perchaud V, Gautier-Bertrand M, Grabli D, Amarenco P. Association between influenza vaccination and reduced risk of brain infarction. Stroke 33, 513–518 (2002).
   PubMed Web of Science ®Google Scholar
• Grau AJ, Fishcer B, Barth C, Ling P, Lichy C, Buggle F. Influenza vaccination is associated with a reduced risk of stroke. Stroke 36, 1501–1506 (2005).
   PubMed Web of Science ®Google Scholar
• Gurfinkel EP, de la Fuente L, Mendiz O, Mautner B. Influenza vaccine pilot study in acute coronary syndromes and planned percutaneous coronary interventions: the FLU Vaccination Acute Coronary Syndromes (FLUVACS) Study. Circulation 105, 2143–2147 (2005).
   Google Scholar
• Ohashi R, Mu H, Yao Q, Chen C. Atherosclerosis: immunopathogenesis and immunotherapy. Med. Sci. Monit. 10, RA255–RA260 (2004).
   PubMed Web of Science ®Google Scholar
• Zhou X, Hansson GK. Immunomodulation and vaccination for atherosclerosis. Expert Opin. Biol. Ther. 4, 599–612 (2004).
   PubMed Web of Science ®Google Scholar