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Expert Review of Neurotherapeutics Volume 7, 2007 - Issue 1
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Key Paper Evaluation

Schizophrenia: more evidence for less glutamate

Paul D Morrison Institute of Psychiatry, De Crespigny Hill, London SE5 8AF, UK
&
Lyn S Pilowsky Institute of Psychiatry., De Crespigny Hill, London SE5 8AF, UK. [email protected]
Pages 29-31 | Published online: 09 Jan 2014

References

  • Hahn CG, Hoau-Yan W, Dan-Sung C et al. Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia. Nat. Med. 12(7), 824–828 (2006).
  • Stefansson H, Sigurdsson E, Steinthorsdottir V et al. Neuregulin 1 and susceptibility to schizophrenia. Am. J. Hum. Genet. 71(4), 877–892 (2002).
  • Li D, Collier DA, He L. Meta-analysis shows strong positive association of the neuregulin 1 (NRG1) gene with schizophrenia. Hum. Mol. Genet. 15(12), 1995–2002 (2006).
  • Buonanno A, Fischbach GD. Neuregulin and ErbB receptor signaling pathways in the nervous system. Curr. Opin. Neurobiol. 11(3), 287–296 (2001).
  • Esper RM, Pankonin MS, Loeb JA. Neuregulins: versatile growth and differentiation factors in nervous system development and human disease. Brain Res. Rev. 51(2), 161–175 (2006).
  • Garcia RA, Vasudevan K, Buonanno A. The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses. Proc. Natl Acad. Sci. USA 97(7), 3596–3601 (2000).
  • Huang YZ, Won S, Ali DW et al. Regulation of neuregulin signaling by PSD-95 interacting with ErbB4 at CNS synapses. Neuron 26(2), 443–455 (2000).
  • Gu Z, Jiang Q, Fu AK, Ip NY, Yan Z. Regulation of NMDA receptors by neuregulin signaling in prefrontal cortex. J. Neurosci. 25(20), 4974–4984 (2005).
  • Olney JW, Newcomer JW, Farber NB. NMDA receptor hypofunction model of schizophrenia. J. Psychiatr. Res. 33(6), 523–533 (1999).
  • Goff DC, Coyle JT. The emerging role of glutamate in the pathophysiology and treatment of schizophrenia. Am. J. Psychiatry 158(9), 1367–1377 (2001).
  • Lane HY, Chang YC, Liu YC, Chiu CC, Tsai GE. Sarcosine or D-serine add-on treatment for acute exacerbation of schizophrenia: a randomized, double-blind, placebo-controlled study. Arch. Gen. Psychiatry 62(11), 1196–2004 (2005).
  • Lynch G, Gall CM. Ampakines and the threefold path to cognitive enhancement. Trends Neurosci. 29(10), 554–562 (2006).
  • Salter MW, Kalia LV. Src kinases: a hub for NMDA receptor regulation. Nat. Rev. Neurosci. 5(4), 317–328 (2004).

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