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Editorial

A neuroimmunologist’s perspective on Alzheimer’s disease therapy

Pages 439-441 | Published online: 09 Jan 2014

References

  • Nicholl JAR, Wilkinson D, Holmes C, Steart P, Markham H, Weller RO. Neuropathology of human Alzheimer disease after immunization with amyloid-β-peptide: a case report. Nat. Med.9, 448–452 (2003).
  • Pfeifer M, Boncristiano S, Bondolfi L et al. Cerebral hemorrhage after passive anti-Aβ immunotherapy. Science298, 1379 (2002).
  • Istrin G, Bosis E, Solomon B. Intravenous immunoglobulin enhances the clearance of fibrillar amyloid-β peptide. J. Neurosci. Res.84(2), 434–443 (2006).
  • Carty NC, Wilcock DM, Rosenthal A et al. Intracranial administration of deglycosylated C-terminal-specific anti-Aβ antibody efficiently clears amyloid plaques without activating microglia in amyloid-depositing transgenic mice. J. Neuroinflammation3, 11 (2006).
  • Schenk D, Barbour R, Dunn W et al. Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature400(6740), 173–177 (1999).

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