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Special Report

Migraine and epilepsy: genetically linked?

, , &
Pages 1307-1311 | Published online: 09 Jan 2014

References

  • Haan J, Terwindt GM, van den Maagdenberg AMJM, Stam AH, Ferrari MD. A review of the genetic relation between migraine and epilepsy. Cephalalgia28, 105–113 (2008).
  • Ottman R, Lipton RB. Comorbidity of migraine and epilepsy. Neurology44, 2105–2110 (1994).
  • Ludvigsson P, Hesdorffer D, Olafsson E, Kjartansson O, Hauser WA. Migraine with aura is a risk factor for unprovoked seizures in children. Ann. Neurol.59, 210–213 (2006).
  • Van den Maagdenberg AMJM, Haan J, Terwindt GM, Ferrari MD. Migraine: gene mutations and functional consequences. Curr. Opin. Neurol.20, 299–305 (2007).
  • Headache classification subcommittee of the international headache society. The International Classification of Headache Disorders. 2nd Edition. Cephalalgia24(Suppl. 1), 1–160 (2004).
  • Gourfinkel-An I, Baulac S, Nabbout R et al. Monogenic idiopathic epilepsies. Lancet Neurol.3, 209–218 (2004).
  • Stam AH, van den Maagdenberg AMJM, Haan J, Terwindt GM, Ferrari MD. Genetics of migraine: an update with special attention for genetic co-morbidity. Curr. Opin. Neurol.21, 288–293 (2008).
  • Stam AH, Vanmolkot KR, Kremer HP et al.CACNA1A R1347Q: a frequent recurrent mutation in hemiplegic migraine. Clin. Genet. (2008) (Epub ahead of print).
  • Vanmolkot KR, Kors EE, Hottenga JJ et al. Novel mutations in the Na+, K+-ATPase pump gene ATP1A2 associated with familial hemiplegic migraine and benign familial infantile convulsions. Ann. Neurol.54, 360–366 (2003).
  • Lebas A, Guyant-Marechal L, Hannequin D, Riant F, Tournier-Lasserve E, Parain D. Severe attacks of familial hemiplegic migraine, childhood epilepsy and ATP1A2 mutation. Cephalalgia28(7), 774–777 (2008).
  • Deprez L, Weckhuysen S, Peeters K et al. Epilepsy as part of the phenotype associated with ATP1A2 mutations. Epilepsia49, 500–508 (2008).
  • Martinelli BF, Aridon P, Zara F et al. No evidence of ATP1A2 involvement in 12 multiplex Italian families with benign familial infantile seizures. Neurosci. Lett.388, 71–74 (2005).
  • Buono RJ, Ferraro TN, O’Connor MJ et al. Lack of association between temporal lobe epilepsy and a novel polymorphism in the α2 subunit gene (ATP1A2) of the sodium potassium transporting ATPase. Am. J. Med. Genet.96, 79–83 (2000).
  • Lohoff FW, Ferraro TN, Sander T et al. No association between common variations in the human α2 subunit gene (ATP1A2) of the sodium-potassium-transporting ATPase and idiopathic generalized epilepsy. Neurosci. Lett.382, 33–38 (2005).
  • Dichgans M, Freilinger T, Eckstein G et al. Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine. Lancet366, 371–377 (2005).
  • Vanmolkot KR, Babini E, de Vries BB et al. The novel L1649Q mutation in the SCN1A epilepsy gene is associated with familial hemiplegic migraine: genetic and functional studies. Hum. Mut.28, 522 (2007).
  • Haut SR, Bigal ME, Lipton RB. Chronic disorders with episodic manifestations: focus on epilepsy and migraine. Lancet Neurol.5, 148–157 (2006).
  • Coppola G, Pierelli F, Schoenen J. Is the cerebral cortex hyperexcitable or hyperresponsive in migraine? Cephalalgia27, 1429–1439 (2007).
  • Curra A, Pierelli F, Coppola G et al. Shortened cortical silent period in facial muscles of patients with migraine. Pain132, 124–131 (2007).
  • Siniatchkin M, Moeller F, Sheperd A, Siebner H, Stephani U. Altered cortical visual processing in individuals with a spreading photoparoxysmal EEG response. Eur. J. Neurosci.26, 529–536 (2007).
  • Steinlein OK. Genetic mechanisms that underlie epilepsy. Nat. Rev. Neurosci.5, 400–408 (2004).
  • Van de Ven RCG, Kaja S, Plomp JJ, Frants RR, Van den Maagdenberg AMJM, Ferrari MD. Genetic models of migraine. Arch. Neurol.64, 643–646 (2007).
  • Hadjikhani N, Sanchez del Rio M, Wu O et al. Mechanisms of migraine aura revealed by functional MRI in human visual cortex. Proc. Natl Acad. Sci. USA98, 4687–4692 (2001).
  • Gorji A, Speckmann EJ. Spreading depression enhances the spontaneous epileptiform activity in human neocortical tissues. Eur. J. Neurosci.19, 3371–3374 (2004).
  • Koch UR, Musshoff U, Pannek HW et al. Intrinsic excitability, synaptic potentials, and short-term plasticity in human epileptic neocortex. J. Neurosci. Res.80, 715–726 (2005).
  • De Simone R, Ranieri A, Marano E et al. Migraine and epilepsy: Clinical and pathophysiological considerations. Neurol. Sci.28, S150-S155 (2007).
  • Burstein R, Yarnitsky D, Goor-Arych I et al. An association between migraine and cutaneous allodynia. Ann. Neurol.47, 614–624 (2000).
  • Bergerot A, Holland PR, Akerman S et al. Animal models of migraine: looking at the component parts of a complex disorder. Eur. J. Neurosci.24, 1517–1534 (2006).
  • Tokuda S, Kuramoto T, Tanaka K et al. The ataxic groggy rat has a missense mutation in the P/Q-type voltage-gated Ca2+ channel α-1A subunit gene and exhibits absence seizures. Brain Res.1133, 168–177 (2007).
  • Ayata C, Shimizu-Sasamata M, Lo EH, Noebels JL, Moskowitz MA. Impaired neurotransmitter release and elevated threshold for cortical spreading depression in mice with mutations in the α1A subunit of P/Q type calcium channels. Neuroscience95, 639–645 (2000).
  • Van den Maagdenberg AMJM, Pietrobon D, Pizzorusso T et al.A Cacna1a knockin migraine mouse model with increased susceptibility to cortical spreading depression. Neuron41, 701–710 (2004).
  • Yu FH, Mantegazza M, Westenbroek RE et al. Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy. Nat. Neurosci.9, 1142–1149 (2006).
  • Ogiwara I, Miyamoto H, Morita N et al. Nav1.1 Localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an SCN1A gene mutation. J. Neurosci.27, 5903–5914 (2007).
  • Kearney JA, Plummer NW, Smith MR et al. A gain-of-function mutation in the sodium channel gene Scn2a results in seizures and behavioral abnormalities. Neuroscience102, 307–317 (2001).
  • Calabresi P, Galletti F, Rossi C, Sarchielli P, Cupini LM. Antiepileptic drugs in migraine: from clinical aspects to cellular mechanism. Trends Pharmacol. Sci.28, 188–195 (2007).
  • Ayata C, Jin H, Kudo C, Dalkara T, Moskowitz MA. Suppression of cortical spreading depression in migraine prophylaxis. Ann. Neurol.59, 652–661 (2006).
  • Kaczmarek LK. Non-conducting functions of voltage-gated ion channels. Nat. Rev. Neurosci.7, 761–771 (2006).
  • Ashcroft FM. From molecule to malady. Nature440, 440–447 (2006).

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