36
Views
4
CrossRef citations to date
0
Altmetric
Drug Evaluation

Cilostazol: improving walking distance in patients with intermittent claudication

&
Pages 503-509 | Published online: 10 Jan 2014

References

  • Hiatt WR. Medical treatment of peripheralarterial disease and claudication. N Engl J. Med 344, 1608–1621 (2001).
  • Fowkes F, Housley E, Cawood E et al Edinburgh artery study: prevalence of asymptomatic and symptomatic peripheral arterial disease in the general population. mt. J Epidemid 20, 384–392 (1991).
  • Kannel WB, McGee DI. Update on some epidemiological features on intermittent claudication. J. Am. Geriatr Soc. 33, 13–18 (1985).
  • Regensteiner JG, Steiner JF, Hiatt WR. Exercise training improves functional status in patients with peripheral arterial disease. J Vasc. Surg 23(1), 104–115 (1996).
  • Collinson DJ, Donnelly R Therapeutic angiogenesis in the lower limb: can biotechnology produce an effective collateral circulation? Eur J Vasc. Endovasc. Surg 28, 9–23 (2004).
  • Lederman RJ, Mendelsohn FO, Anderson RD et al. Therapeutic angiogenesis with recombinant fibroblast growth factor-2 for intermittent claudication (the TRAFFIC study): a randomized trial. Lancet 359, 2053–2058 (2002).
  • Donnelly R, Yeung JM. Management of intermittent claudication: the importance of secondary prevention. Eur. J. Vasc. Endovasc. Surg. 23,100-107 (2002).
  • Donnelly R. Pletal: symptom relief in intermittent claudication. Prescriber 26–32 (2003).
  • Gotoh F, Tohgi H, Hirai S et al. Cilostazol Stroke Prevention Study: a placebo-controlled double-blind trial for secondary prevention of cerebral infarction. J. Stroke Cerebrovasc. Dis. 9, 147–157 (2000)
  • Schrör K. The pharmacology of cilostazol. Diabetes Obes. Metab. 4, S14—S19 (2002).
  • Liu Y, Fong M, Cone J, Wang S, Yoshitake M, Kambayashi J. Inhibition of adenosine uptake and augmentation of ischemia-induced increase of interstitial adenosine by cilostazol, an agent to treat intermittent claudication. J. Cardiovasc. Pharmacol 36, 351–360 (2000).
  • Chapman TM, Goa KL. Cilostazol. A review of its use in intermittent claudication. Am. J. Cardiovasc. Drugs 3(2), 117–138 (2003).
  • Takahashi S, Oida K, Fujiwara R et al. Effect of cilostazol, a cyclic AMP phosphodiesterase inhibitor, on the proliferation of rat aortic smooth muscle cells in culture. J. Cardiovasc. Pharmacol 20, 900–906 (1992).
  • Elam MB, Heckman J, Crouse JR et al Effect of the novel antiplatelet agent cilostazol on plasma lipoproteins in patients with intermittent claudication. Arterioscler. Thromb. Vasc. Bid 18, 1942–1947 (1998).
  • Nishio Y, Kashiwagi A, Takahara N, Hidaka H, Kikkawa R Cilostazol, a cAMP phosphodiesterase inhibitor, attenuates the production of monocyte chemoattractant protein-1 in response to tumour necrosis factor-a in vascular endothelial cells. Harm. Metab. Res. 29, 491–495 (1997)
  • Aoki M, Morishita R, Hayashi S et al. Inhibition of neointimal formation after balloon injury by cilostazol, accompanied by improvement of endothelial dysfunction and induction of hepatocyte growth factor in a rat diabetes model. Diabetalogia 44, 1034–1042 (2001).
  • Lee T-M, Su S-F, Tsai C-H et al. Differential effects of cilostazol and pentoxyfilline on vascular endothelial growth factor in patients with intermittent claudication. Clin. Sci. (London) 101(3), 305–311 (2001).
  • Bramer SL, Forbes WE Mallikaarjun S. Cilostazol pharmacokinetics after single and multiple oral doses in healthy males and patients in with intermittent claudication resulting form peripheral arterial disease. Clin. Pharmacokinet. 37, 1–11 (1999).
  • Bramer SL, Forbes WP. Relative bioavailability and effects of a high fat meal on single dose cilostazol pharmacokinetics. Clin. Pharmacokinet. 37(Suppl. 2), 113–123 (1999).
  • Suni A, Forbes WP, Bramer SL. Effects of CYP3A inhibition on the metabolism of cilostazol. Clin. Pharmacokinet. 37,61–68 (1999).
  • Mallikaarjun S, Bramer SL, Bortey E et al. Pharmacodynamic—pharmacokinetic interaction of aspirin with cilostazol. Clin. Pharmacol Ther. 63,231 (1998).
  • Mallikaarjun S, Mico BA, Forbes WP A pharmacokinetic and pharmacodynamic study of the potential interaction between cilostazol and warfarin. Pharm. Res. 14, S555 (1997).
  • White DB, Comerota AJ, Schmieder FA, Throm RC, Gaughan JP, Rao AK. Managing PAD with multiple platelet inhibitors: the effect of combination therapy on bleeding time. J. Vasc. Surg. 38, 710–713 (2003).
  • Strandness DE Jr, Dalman RE, Panian S et al Effect of cilostazol in patients with intermittent claudication: a randomized, double-blind, placebo-controlled study. Vasc. Endovasc. Surg 36(2), 83–91 (2002).
  • Dawson DL, Cutler BS, Hiatt VIR et al. A comparison of cilostazol and pentoxyfilline for treating intermittent claudication. Am. J. Med. 109(7), 523–530 (2000).
  • •Large multicenter trial comparing the effects of cilostazol, placebo and pentoxifylline on treadmill walking distance.
  • Beebe HG, Dawson DL, Cutler BS et al. A new pharmacological treatment for intermittent claudication: results of a randomized, multicenter trial. Arch. Intern. Med. 159(17), 2041–2050 (1999).
  • Dawson DL, Cutler BS, Meissner MH et al Cilostazol has beneficial effects in treatment of intermittent claudication: results of a multicentre, randomized, prospective, double-blind trial. Circulation 98(7), 678–686 (1998).
  • Money SR, Herd JA, Isaacsohn JL et al Effect of cilostazol on walking distances in patients with intermittent claudication caused by peripheral arterial disease. J. Vasc. Surg. 27(2), 267–274 (1998).
  • Thompson PD, Zimet R, Forbes WP, Zhang P. Meta-analysis of results from eight randomized, placebo-controlled trials on the effect of cilostazol on patients with intermittent claudication. Am. J. Cardiol 90,1314–1319 (2002).
  • Pratt CM. Analysis of the cilostazol safety database. Am. J. Cardiol 87(12A), D28—D33 (2001).
  • Packer M, Carver JR, Rodeheffer RJ. et al. Effect of oral milrinone on mortality in severe chronic heart failure. The PROMISE Study Research Group. N Engl J. Med. 325(3), 634–640 (1991).
  • Cone J, Wang S, Tandon N et al. Comparison of the effects of cilostazol and milrinone on intracellular cAMP levels and cellular function in platelets and cardiac cells. J. Cardiovasc. Pharmacol. 34(4), 497–504 (1999).
  • •Demonstrates that cilostazol and milrinone, both phosphodiesterase-3 inhibitors, have different effects on cAMP levels, which in turn might explain why cilostazol has not been associated with the adverse cardiovascular effects noted with milrinone.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.