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Editorial

Cardiovascular risks of cyclooxygenase-2 inhibitors and traditional anti-inflammatory drugs: necessary but not sufficient for clinical decision making

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References

  • Hennekens CH, Borzak S. Cyclooxygenase 2 inhibitors and most traditional nonsteroidal anti-inflammatory drugs produce similar moderately increased risks of cardiovascular disease. J Cardiovasc Pharmacol Ther 2008;13(1):41-50
  • Hennekens CH, DeMets D. Statistical association and causation: contributions of different types of evidence. JAMA 2011;306:1134-6
  • Hennekens CH, DeMets D. The need for large scale randomized evidence without undue emphasis on small trials, meta-analyses or subgroup analyses. JAMA 2009;302:2361-2
  • Hennekens CH, DeMets D. Data and safety monitoring boards of randomized trials: emerging principles and practical suggestions. Clin Invest ( In Press)
  • COXIB and Traditional NSAID Trialists' (CNT) Collaboration. Bhala N, Emberson J, et al. Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials. Lancet 2013;382(9894):769-7
  • Chan FKL, Chung SCS, Suen BY, et al. Preventing recurrent upper gastrointestinal bleeding in patients with Helicobacter pylori infection who are taking low-dose aspirin or naproxen. N Engl J Med 2001;344:967-73
  • Antman EM, Bennett JS, Daugherty A, et al. Use of non-steroidal anti-inflammatory drugs: an update for clinicians: a scientific statement from the American Heart Association. Circulation 2007;115(12):1634-42

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