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Darapladib for the treatment of cardiovascular disease

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References

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  • A Phase 2 Clinical study to investigate effects of darapladib in subjects with diabetic macular edema. Available from: http://clinicaltrials.gov/show/NCT01506895
  • To Estimate the potential effects of repeat doses of darapladib on the pharmacokinetics (PK) of rosuvastatin as well as evaluating safety and tolerability in healthy volunteers. Available from: http://clinicaltrials.gov/show/NCT01751074
  • A healthy volunteer pharmacokinetic study of single and repeat doses of SB-480848. Available from: http://clinicaltrials.gov/show/NCT00743860
  • A Study investigating the concentrations of darapladib in blood and the safety of this compound in healthy Japanese men. Available from: http://clinicaltrials.gov/show/NCT00551317
  • A study with darapladib to collect tolerability information. Available from: http://clinicaltrials.gov/show/NCT00704431
  • Study to determine the effect of repeated administration of diltiazem on the pharmacokinetics of darapladib (Sb-480848). Available from: http://clinicaltrials.gov/show/NCT01852565
  • Pharmacokinetic interaction of Darapladib and CYP 3A4 in healthy subjects. Available from: http://clinicaltrials.gov/show/NCT01873339
  • A Study to assess the pharmacokinetics, safety and tolerability of repeat oral doses of darapladib (SB-480848) in subjects with severe renal impairment. Available from: http://clinicaltrials.gov/show/NCT01711723
  • Study of the effects of SB 480848 (Darapladib) On the electrical conduction of the heart. Available from: http://clinicaltrials.gov/show/NCT00411073
  • Study to evaluate darapladib in moderately hepatically impaired subjects. Available from: http://clinicaltrials.gov/show/NCT01154114
  • Effect of darapladib on cantharidin-induced inflammatory blisters in subjects with Type 2 Diabetes mellitus (T2DM). Available from: http://clinicaltrials.gov/show/NCT02058641

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