567
Views
31
CrossRef citations to date
0
Altmetric
Review

The effect of pregestational diabetes on fetal heart function

References

  • Jenkins KJ, Correa A, Feinstein JA, et al. American Heart Association Council on Cardiovascular Disease in the Young. Noninherited risk factors and congenital cardiovascular defects: current knowledge: a scientific statement from the American Heart Association Council on Cardiovascular Disease in the Young: endorsed by the American Academy of Pediatrics. Circulation 2007;115(23):2995-3014
  • Zielinsky P, Piccoli ALJr. Myocardial hypertrophy and dysfunction in maternal diabetes. Early Hum Dev 2012;88(5):273-8
  • Passarella G, Trifirò G, Gasparetto M, et al. Disorders in glucidic metabolism and congenital heart diseases: detection and prevention. Pediatr Cardiol 2013;34(4):931-7
  • Stuart A, Amer-Wåhlin I, Persson J, Källen K. Long-term cardiovascular risk in relation to birth weight and exposure to maternal diabetes mellitus. Int J Cardiol 2013;168(3):2653-7
  • Moazzen H, Lu X, Ma NL, et al. N-Acetylcysteine prevents congenital heart defects induced by pregestational diabetes. Cardiovasc Diabetol 2014;13(1):46
  • Starikov R, Bohrer J, Goh W, et al. Hemoglobin A1c in pregestational diabetic gravidas and the risk of congenital heart disease in the fetus. Pediatr Cardiol 2013;34(7):1716-22
  • Huybrechts KF, Palmsten K, Avorn J, et al. Antidepressant use in pregnancy and the risk of cardiac defects. N Engl J Med 2014;370(25):2397-407
  • Weber HS, Copel JA, Reece EA, et al. Cardiac growth in fetuses of diabetic mothers with good metabolic control. J Pediatr 1991;118(1):103-7
  • Shields LE, Gan EA, Murphy HF, et al. The prognostic value of hemoglobin A1c in predicting fetal heart disease in diabetic pregnancies. Obstet Gynecol 1993;81(6):954-7
  • Bernard LS, Ramos GA, Fines V, Hull AD. Reducing the cost of detection of congenital heart disease in fetuses of women with pregestational diabetes mellitus. Ultrasound Obstet Gynecol 2009;33(6):676-82
  • Vargas R, Repke JT, Ural SH. Type 1 diabetes mellitus and pregnancy. Rev Obstet Gynecol 2010;3(3):92-100
  • Lawrence JM, Contreras R, Chen W, Sacks DA. Trends in the prevalence of preexisting diabetes and gestational diabetes mellitus among a racially/ethnically diverse population of pregnant women, 1999–2005. Diabetes Care 2008;31:899-904
  • Nolan CJ, Damm P, Prentki M. Type 2 diabetes across generations: from pathophysiology to prevention and management. Lancet 2011;378(9786):169-81
  • Chu C, Gui YH, Ren YY, Shi LY. The impacts of maternal gestational diabetes mellitus (GDM) on fetal hearts. Biomed Environ Sci 2012;25(1):15-22
  • Clausen TD, Mathiesen E, Ekbom P, et al. Poor pregnancy outcome in women with type 2 diabetes. Diabetes Care 2005;28(2):323-8
  • Figueroa H, Silva MC, Kottmann C, et al. Fetal evaluation of the modified-myocardial performance index in pregnancies complicated by diabetes. Prenat Diagn 2012;32(10):943-8
  • Lehtoranta L, Vuolteenaho O, Laine VJ, et al. Maternal hyperglycemia leads to fetal cardiac hyperplasia and dysfunction in a rat model. Am J Physiol Endocrinol Metab 2013;305(5):E611-19
  • El-Ganzoury MM, El-Masry SA, El-Farrash RA, et al. Infants of diabetic mothers: echocardiographic measurements and cord blood IGF-I and IGFBP-1. Pediatr Diabetes 2012;13(2):189-96
  • Arslan D, Oran B, Vatansev H, et al. The usefulness of plasma asymmetric dimethylarginine (ADMA) levels and tissue Doppler echocardiography for heart function in term infants born to mothers with gestational diabetes mellitus. J Matern Fetal Neonatal Med 2013;26(17):1742-8
  • Eslamian L, Akbari S, Marsoosi V, Jamal A. Association between fetal overgrowth and metabolic parameters in cord blood of newborns of women with GDM. Minerva Med 2013;104(3):317-24
  • Lindegaard ML, Nielsen LB. Maternal diabetes causes coordinated down-regulation of genes involved with lipid metabolism in the murine fetal heart. Metabolism 2008;57(6):766-73
  • Madsen NL, Schwartz SM, Lewin MB, Mueller BA. Prepregnancy body mass index and congenital heart defects among offspring: a population-based study. Congenit Heart Dis 2013;8(2):131-41
  • Cheng X, Chapple SJ, Patel B, et al. Gestational diabetes mellitus impairs Nrf2-mediated adaptive antioxidant defenses and redox signaling in fetal endothelial cells in utero. Diabetes 2013;62(12):4088-97
  • Pisaneschi S, Boldrini A, Genazzani AR, et al. Feto-placental vascular dysfunction as a prenatal determinant of adult cardiovascular disease. Intern Emerg Med 2013;8(Suppl 1)):S41-5
  • Goulopoulou S, Hannan JL, Matsumoto T, et al. Augmented dilation to nitric oxide in uterine arteries from rats with type 2 diabetes: implications for vascular adaptations to pregnancy. Am J Physiol Heart Circ Physiol 2014;306(4):H610-18
  • Boney CM, Verma A, Tucker R, Vohr BR. Metabolic syndrome in childhood: association with birth weight, maternal obesity, and gestational diabetes mellitus. Pediatrics 2005;115(3):e290-6
  • Yajnik CS. Transmission of obesity-adiposity and related disorders from the mother to the baby. Ann Nutr Metab 2014;64(Suppl 1):8-17
  • Crispi F, Gratacós E. Fetal cardiac function: technical considerations and potential research and clinical applications. Fetal Diagn Ther 2012;32(1-2):47-64
  • Rogers L, Li J, Liu L, et al. Advances in fetal echocardiography: early imaging, three/four dimensional imaging, and role of fetal echocardiography in guiding early postnatal management of congenital heart disease. Echocardiography 2013;30:428-38
  • Hernandez-Andrade E, Benavides-Serralde JA, Cruz-Martinez R, et al. Evaluation of conventional Doppler fetal cardiac function parameters: E/A ratios, outflow tracts, and myocardial performance index. Fetal Diagn Ther 2012;32(1-2):22-9
  • Cruz-Martínez R, Figueras F, Bennasar M, et al. Normal reference ranges from 11 to 41 weeks’ gestation of fetal left modified myocardial performance index by conventional Doppler with the use of stringent criteria for delimitation of the time periods. Fetal Diagn Ther 2012;32(1-2):79-86
  • Friedman D, Buyon J, Kim M, Glickstein JS. Fetal cardiac function assessed by Doppler myocardial performance index (Tei index). Ultrasound Obstet Gynecol 2003;33-6
  • Ghawi H, Gendi S, Mallula K, et al. Fetal left and right ventricle myocardial performance index: defining normal values for the second and third trimesters--single tertiary center experience. Pediatr Cardiol 2013;34(8):1808-15
  • Russell NE, Foley M, Kinsley BT, et al. Effect of pregestational diabetes mellitus on fetal cardiac function and structure. Am J Obstet Gynecol 2008;199(3):312.e1-7
  • Harada K, Tsuda A, Orino T, et al. Tissue Doppler imaging in the normal fetus. Int J Cardiol 1999;71:227-34
  • Saini AP, Ural S, Pauliks LB. Quantitation of fetal heart function with tissue Doppler velocity imaging-reference values for color tissue Doppler velocities and comparison with pulsed wave tissue Doppler velocities. Artif Organs 2014;38(1):87-91
  • Paladini D, Lamberti A, Teodoro A, et al. Tissue Doppler imaging of the fetal heart. Ultrasound Obstet Gynecol 2000;16:530-5
  • Chan LY, Fok WY, Wong JT, et al. Reference charts of gestation-specific tissue Doppler imaging indices of systolic and diastolic functions in the normal fetal heart. Am Heart J 2005;150:750-5
  • Comas M, Crispi F, Gómez O, et al. Gestational age- and estimated fetal weight-adjusted reference ranges for myocardial tissue Doppler indices at 24–41 weeks’ gestation. Ultrasound Obstet Gynecol 2011;37:57-64
  • Gardiner HM, Pasquini L, Wolfenden J, et al. Increased periconceptual maternal glycated haemoglobin in diabetic mothers reduces fetal long axis cardiac function. Heart 2006;92(8):1125-30
  • Harada K, Ogawa M, Tanaka T. Right ventricular pre-ejection myocardial velocity and myocardial acceleration in normal fetuses assessed by Doppler tissue imaging. J Am Soc Echocardiogr 2005;18:370-4
  • Huhta JC, Kales E, Casbohm A. Fetal tissue Doppler – a new technique for perinatal cardiology. Curr Opin Pediatr 2003;15:472-4
  • Twining P. Myocardial motion imaging: a new application of power color flow and frequency-based color flow Doppler in fetal echocardiography. Ultrasound Obstet Gynecol 1999;13:255-9
  • Elmstedt NN, Johnson JJ, Lind BB, et al. Reference values for fetal tissue velocity imaging and a new approach to evaluate fetal myocardial function. Cardiovasc Ultrasound 2013;11:29
  • Younoszai AK, Saudek DE, Emery SP, Thomas JD. Evaluation of myocardial mechanics in the fetus by velocity vector imaging. J Am Soc Echocardiogr 2008;21(5):470-4
  • Peng QH, Zhou QC, Zeng S, et al. Evaluation of regional left ventricular longitudinal function in 151 normal fetuses using velocity vector imaging. Prenat Diagn 2009;29(12):1149-55
  • Barker PC, Houle H, Li JS, et al. Global longitudinal cardiac strain and strain rate for assessment of fetal cardiac function: novel experience with velocity vector imaging. Echocardiography 2009;26(1):28-36
  • Matsui H, Germanakis I, Kulinskaya E, Gardiner HM. Temporal and spatial performance of vector velocity imaging in the human fetal heart. Ultrasound Obstet Gynecol 2011;37(2):150-7
  • Heimdal A, Støylen A, Torp H, Skjaerpe T. Real-time strain rate imaging of the left ventricle by ultrasound. J Am Soc Echocardiogr 1998;11(11):1013-19
  • Di Salvo G, Russo MG, Paladini D, et al. Quantification of regional left and right ventricular longitudinal function in 75 normal fetuses using ultrasound-based strain rate and strain imaging. Ultrasound Med Biol 2005;31:1159-62
  • Di Salvo G, Russo MG, Paladini D, et al. Two-dimensional strain to assess regional left and right ventricular longitudinal function in 100 normal foetuses. Eur J Echocardiogr 2008;9(6):754-6
  • Willruth AM, Geipel AK, Fimmers R, Gembruch UG. Assessment of right ventricular global and regional longitudinal peak systolic strain, strain rate and velocity in healthy fetuses and impact of gestational age using a novel speckle/feature-tracking based algorithm. Ultrasound Obstet Gynecol 2011;37(2):143-9
  • Germanakis I, Gardiner H. Assessment of fetal myocardial deformation using speckle tracking techniques. Fetal Diagn Ther 2012;32(1-2):39-46
  • Van Mieghem T, Giusca S, DeKoninck P, et al. Prospective assessment of fetal cardiac function with speckle tracking in healthy fetuses and recipient fetuses of twin-to-twin transfusion syndrome. J Am Soc Echocardiogr 2010;23(3):301-8
  • Crispi F, Sepulveda-Swatson E, Cruz-Lemini M, et al. Feasibility and reproducibility of a standard protocol for 2D speckle tracking and tissue Doppler-based strain and strain rate analysis of the fetal heart. Fetal Diagn Ther 2012;32(1-2):96-108
  • Gomez KJ, Dowdy K, Allen G, et al. Evaluation of ultrasound diagnosis of fetal anomalies in women with pregestational diabetes: university of Florida experience. Am J Obstet Gynecol 1988;159(3):584-6
  • Weiner Z, Zloczower M, Lerner A, et al. Cardiac compliance in fetuses of diabetic women. Obstet Gynecol 1999;93(6):948-51
  • Hatém MA, Zielinsky P, Hatém DM, et al. Assessment of diastolic ventricular function in fetuses of diabetic mothers using tissue Doppler. Cardiol Young 2008;18(3):297-302
  • Garcia-Flores J, Jañez M, Gonzalez MC, et al. Fetal myocardial morphological and functional changes associated with well-controlled gestational diabetes. Eur J Obstet Gynecol Reprod Biol 2011;154(1):24-6
  • Costa VN, Nomura RM, Reynolds KS, et al. Effects of maternal glycemia on fetal heart rate in pregnancies complicated by pregestational diabetes mellitus. Eur J Obstet Gynecol Reprod Biol 2009;143(1):14-17
  • Costa VN, Nomura RM, Reynolds KS, et al. Fetal and neonatal atrial arrhythmias: an association with maternal diabetes and neonatal macrosomia. Prenat Diagn 2013;33(12):1152-7
  • Pike JI, Krishnan A, Kaltman J, Donofrio MT. Fetal and neonatal atrial arrhythmias: An association with maternal diabetes and neonatal macrosomia. Prenat Diagn 2013;33:1152-7
  • Turan S, Turan OM, Miller J, et al. Decreased fetal cardiac performance in the first trimester correlates with hyperglycemia in pregestational maternal diabetes. Ultrasound Obstet Gynecol 2011;38(3):325-31
  • Bhorat IE, Bagratee JS, Pillay M, et al. Use of the myocardial performance index as a prognostic indicator of adverse fetal outcome in poorly controlled gestational diabetic pregnancies. Prenat Diagn 2014. [Epub ahead of print]
  • Bui YK, Kipps AK, Brook MM, et al. Tissue Doppler is more sensitive and reproducible than spectral pulsed-wave Doppler for fetal right ventricle myocardial performance index determination in normal and diabetic pregnancies. J Am Soc Echocardiogr 2013;26(5):507-14

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.