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Expert Review of Cardiovascular Therapy Volume 14, 2016 - Issue 2
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Reviews

Percutaneous treatment of left main and non-left main bifurcation coronary lesions using drug-eluting stents

Jae-Hyung RohAsan Medical Center - Cardiology Division, University of Ulsan College of Medicine, Seoul, Korea
&
Young-Hak KimAsan Medical Center - Cardiology Division, University of Ulsan College of Medicine, Seoul, KoreaCorrespondence[email protected]
Pages 229-243 | Received 26 Sep 2015, Accepted 11 Nov 2015, Published online: 29 Dec 2015

References

  • Papers of special note have been highlighted as:
  • • of interest
  • •• of considerable interest
  • Thomas MR, Hildick-Smith D, Louvard Y, et al. Percutaneous coronary intervention for bifurcation disease. A consensus view from the first meeting of the European Bifurcation Club. EuroIntervention. 2006;2:149–153.
  • Lassen JF, Holm NR, Stankovic G, et al. Percutaneous coronary intervention for coronary bifurcation disease: consensus from the first 10 years of the European Bifurcation Club meetings. EuroIntervention. 2014;10:545–560.

•• Recent guidelines for the treatment of coronary bifurcations.

  • Kim Y-H, Lee J-H, Roh J-H, et al. Randomized comparisons between different stenting approaches for bifurcation coronary lesions with or without side branch stenosis. JACC Cardiovasc Interv. 2015;8:550–560.

•• Recently published randomized studies comparing routine versus selective final kissing balloon inflation for bifurcations with normal side branches and single- versus double-stent techniques for those with diseased side branches.

  • Colombo A, Bramucci E, Saccà S, et al. Randomized study of the crush technique versus provisional side-branch stenting in true coronary bifurcations: the CACTUS (Coronary Bifurcations: Application of the Crushing Technique Using Sirolimus-Eluting Stents) Study. Circulation. 2009;119:71–78.
  • Colombo A, Moses JW, Morice MC, et al. Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions. Circulation. 2004;109:1244–1249.
  • Ferenc M, Gick M, Kienzle R-P, et al. Randomized trial on routine vs. provisional T-stenting in the treatment of de novo coronary bifurcation lesions. Eur Heart J. 2008;29:2859–2867.
  • Hildick-Smith D, De Belder AJ, Cooter N, et al. Randomized trial of simple versus complex drug-eluting stenting for bifurcation lesions: the British Bifurcation Coronary Study: old, new, and evolving strategies. Circulation. 2010;121:1235–1243.
  • Pan M, De Lezo JS, Medina A, et al. Rapamycin-eluting stents for the treatment of bifurcated coronary lesions: a randomized comparison of a simple versus complex strategy. Am Heart J. 2004;148:857–864.
  • Steigen TK, Maeng M, Wiseth R, et al. Randomized study on simple versus complex stenting of coronary artery bifurcation lesions: the Nordic bifurcation study. Circulation. 2006;114:1955–1961.
  • Katritsis DG, Siontis GCM, Ioannidis JPA. Double versus single stenting for coronary bifurcation lesions a meta-analysis. Circ Cardiovasc Interv. 2009;2:409–415.
  • Zimarino M, Corazzini A, Ricci F, et al. Late thrombosis after double versus single drug-eluting stent in the treatment of coronary bifurcations: a meta-analysis of randomized and observational Studies. JACC Cardiovasc Interv. 2013;6:687–695.
  • Chen S-L, Santoso T, Zhang -J-J, et al. A randomized clinical study comparing double kissing crush with provisional stenting for treatment of coronary bifurcation lesions: results from the DKCRUSH-II (Double Kissing Crush versus Provisional Stenting Technique for Treatment of Coronary Bifurcation Lesions) Trial. J Am Coll Cardiol. 2011;57:914–920.
  • Chen S-L, Sheiban I, Xu B, et al. Impact of the complexity of bifurcation lesions treated with drug-eluting stents: the DEFINITION Study (Definitions and impact of complEx biFurcation lesIons on clinical outcomes after percutaNeous coronary IntervenTIOn using drug-eluting steNts). JACC Cardiovasc Interv. 2014;7:1266–1276.
  • Vaquerizo B, Lefèvre T, Darremont O, et al. Unprotected left main stenting in the real world two-year outcomes of the French left main taxus registry. Circulation. 2009;119:2349–2356.
  • Hahn J-Y, Chun WJ, Kim J-H, et al. Predictors and outcomes of side branch occlusion after main vessel stenting in coronary bifurcation lesions: results from the COBIS II Registry (COronary BIfurcation Stenting). J Am Coll Cardiol. 2013;62:1654–1659.
  • Choy JS, Kassab GS. Scaling of myocardial mass to flow and morphometry of coronary arteries. J Appl Physiol. 2008;104:1281–1286.
  • Kassab GS, Bhatt DL, Lefèvre T, et al. Relation of angiographic side branch calibre to myocardial mass: a proof of concept myocardial infarct index. EuroIntervention. 2013;8:1461–1463.
  • Burzotta F, De Vita M, Sgueglia GA, et al. How to solve difficult side branch access? EuroIntervention. 2011;6:J72–J80.
  • Furukawa E, Hibi K, Kosuge M, et al. Intravascular ultrasound predictors of side branch occlusion in bifurcation lesions after percutaneous coronary intervention. Circ J. 2005;69:325–330.
  • Goto Y, Kawasaki T, Koga N, et al. Plaque distribution patterns in left main trunk bifurcations: prediction of branch vessel compromise by multidetector row computed topography after percutaneous coronary intervention. EuroIntervention. 2012;8:708–716.
  • Park JJ, Chun EJ, Cho Y-S, et al. Potential predictors of side-branch occlusion in bifurcation lesions after percutaneous coronary intervention: a coronary CT angiography study. Radiology. 2014;271:711–720.
  • Dou K, Zhang D, Xu B, et al. An angiographic tool for risk prediction of side branch occlusion in coronary bifurcation intervention: the RESOLVE score system (Risk prEdiction of Side branch OccLusion in coronary bifurcation interVEntion). JACC Cardiovasc Interv. 2015;8:39–46.
  • Arora RR, Raymond RE, Dimas AP, et al. Side branch occlusion during coronary angioplasty: incidence, angiographic characteristics, and outcome. Cathet Cardiovasc Diagn. 1989;18:210–212.
  • Meier B, Gruentzig AR, King III SB, et al. Risk of side branch occlusion during coronary angioplasty. Am J Cardiol. 1984;53:10–14.
  • Chaudhry EC, Dauerman KP, Sarnoski CL, et al. Percutaneous coronary intervention for major bifurcation lesions using the simple approach: risk of myocardial infarction. J Thromb Thrombolysis. 2007;24:7–13.
  • Brunel P, Lefevre T, Darremont O, et al. Provisional T-stenting and kissing balloon in the treatment of coronary bifurcation lesions: results of the French multicenter “TULIPE” study. Catheter Cardiovasc Interv. 2006;68:67–73.
  • Ahn J-M, Lee J-Y, Kang S-J, et al. Functional assessment of jailed side branches in coronary bifurcation lesions using fractional flow reserve. JACC Cardiovasc Interv. 2012;5:155–161.

• This study reported the incidence of functionally significant jailed side branches after main branch stenting.

  • Koo B-K, Kang H-J, Youn T-J, et al. Physiologic assessment of jailed side branch lesions using fractional flow reserve. J Am Coll Cardiol. 2005;46:633–637.
  • Koo B-K, Waseda K, Kang H-J, et al. Anatomic and functional evaluation of bifurcation lesions undergoing percutaneous coronary intervention. Circ Cardiovasc Interv. 2010;3:113–119.
  • Koo B-K, Park K-W, Kang H-J, et al. Physiological evaluation of the provisional side-branch intervention strategy for bifurcation lesions using fractional flow reserve. Eur Heart J. 2008;29:726–732.
  • Chen S-L, Ye F, Zhang J-J, et al. Randomized comparison of FFR-guided and angiography-guided provisional stenting of true coronary bifurcation lesions: the DKCRUSH-VI (Double Kissing Crush Versus Provisional Stenting Technique for Treatment of Coronary Bifurcation Lesions VI) Trial. JACC Cardiovasc Interv. 2015;8:536–546.
  • Korn HV, Yu J, Ohlow MA, et al. Interventional therapy of bifurcation lesions: a TIMI flow-guided concept to treat side branches in bifurcation lesions—a prospective randomized clinical study (Thueringer bifurcation study, THUEBIS study as pilot trial). Circ Cardiovasc Interv. 2009;2:535–542.
  • Niemelä M, Kervinen K, Erglis A, et al. Randomized comparison of final kissing balloon dilatation versus no final kissing balloon dilatation in patients with coronary bifurcation lesions treated with main vessel stenting: the Nordic-Baltic Bifurcation Study III. Circulation. 2011;123:79–86.
  • Pan M, Medina A, Suárez de Lezo J, et al. Coronary bifurcation lesions treated with simple approach (from the Cordoba & Las Palmas [CORPAL] Kiss Trial). Am J Cardiol. 2011;107:1460–1465.
  • Gwon H-C, Hahn J-Y, Koo B-K, et al. Final kissing ballooning and long-term clinical outcomes in coronary bifurcation lesions treated with 1-stent technique: results from the COBIS registry. Heart. 2012;98:225–231.
  • Yamawaki M, Muramatsu T, Kozuma K, et al. Long-term clinical outcome of a single stent approach with and without a final kissing balloon technique for coronary bifurcation. Circ J Off J Jpn Circ Soc. 2013;78:110–121.
  • Roh J-H, Lee J-H, Kim Y-H, et al. Procedural predictors of angiographic restenosis after bifurcation coronary stenting (from the choice of optimal strategy for bifurcation lesions with normal side branch and optimal stenting strategy for true bifurcation lesions studies). Am J Cardiol. 2015;116:1050–1056.
  • Foin N, Torii R, Mortier P, et al. Kissing balloon or sequential dilation of the side branch and main vessel for provisional stenting of bifurcations: lessons from micro-computed tomography and computational simulations. JACC Cardiovasc Interv. 2012;5:47–56.
  • Guérin P, Pilet P, Finet G, et al. Drug-eluting stents in bifurcations bench study of strut deformation and coating lesions. Circ Cardiovasc Interv. 2010;3:120–126.
  • Rahman S, Leesar T, Cilingiroglu M, et al. Impact of kissing balloon inflation on the main vessel stent volume, area, and symmetry after side-branch dilation in patients with coronary bifurcation lesions: a serial volumetric intravascular ultrasound study. JACC Cardiovasc Interv. 2013;6:923–931.
  • Louvard Y, Thomas M, Dzavik V, et al. Classification of coronary artery bifurcation lesions and treatments: time for a consensus! Catheter Cardiovasc Interv Off J Soc Card Angiogr Interv. 2008;71:175–183.
  • Chen S-L, Xu B, Han Y-L, et al. Comparison of double kissing crush versus Culotte stenting for unprotected distal left main bifurcation lesions: results from a multicenter, randomized, prospective DKCRUSH-III study. J Am Coll Cardiol. 2013;61:1482–1488.
  • Colombo A, Stankovic G, Orlic D, et al. Modified T-stenting technique with crushing for bifurcation lesions: immediate results and 30-day outcome. Catheter Cardiovasc Interv. 2003;60:145–151.
  • Finn AV, Kolodgie FD, Harnek J, et al. Differential response of delayed healing and persistent inflammation at sites of overlapping sirolimus- or paclitaxel-eluting stents. Circulation. 2005;112:270–278.
  • Awata M, Kotani J, Uematsu M, et al. Serial angioscopic evidence of incomplete neointimal coverage after sirolimus-eluting stent implantation comparison with bare-metal stents. Circulation. 2007;116:910–916.
  • Galassi AR, Colombo A, Buchbinder M, et al. Long-term outcomes of bifurcation lesions after implantation of drug-eluting stents with the “mini-crush technique.”. Catheter Cardiovasc Interv Off J Soc Card Angiogr Interv. 2007;69:976–983.
  • Ormiston JA, Webster MWI, Webber B, et al. The “Crush” technique for coronary artery bifurcation stenting: insights from micro-computed tomographic imaging of bench deployments. JACC Cardiovasc Interv. 2008;1:351–357.
  • Costa RA, Mintz GS, Carlier SG, et al. Bifurcation coronary lesions treated with the “Crush” technique: an intravascular ultrasound analysis. J Am Coll Cardiol. 2005;46:599–605.

• This study investigated scaffolds on intravascular ultrasound after the crush technique.

  • Chen S-L, Mintz G, Kan J, et al. Serial intravascular ultrasound analysis comparing double kissing and classical crush stenting for coronary bifurcation lesions. Catheter Cardiovasc Interv Off J Soc Card Angiogr Interv. 2011;78:729–736.
  • Fan L, Chen L, Luo Y, et al. DK mini-culotte stenting in the treatment of true coronary bifurcation lesions: a propensity score matching comparison with T-provisional stenting. Heart Vessels. 2014. DOI:10.1007/s00380-014-0611-7. [Epub ahead of print]
  • Kervinen K, Niemelä M, Romppanen H, et al. Clinical outcome after crush versus culotte stenting of coronary artery bifurcation lesions: the Nordic Stent Technique Study 36-month follow-up results. JACC Cardiovasc Interv. 2013;6:1160–1165.
  • Kim Y-H, Park D-W, Suh I-W, et al. Long-term outcome of simultaneous kissing stenting technique with sirolimus-eluting stent for large bifurcation coronary lesions. Catheter Cardiovasc Interv Off J Soc Card Angiogr Interv. 2007;70:840–846.
  • Finet G, Gilard M, Perrenot B, et al. Fractal geometry of arterial coronary bifurcations: a quantitative coronary angiography and intravascular ultrasound analysis. EuroIntervention J Eur Collab Work Group Interv Cardiol Eur Soc Cardiol. 2008;3:490–498.
  • Huo Y, Finet G, Lefèvre T, et al. Optimal diameter of diseased bifurcation segment: a practical rule for percutaneous coronary intervention. EuroIntervention. 2012;7:1310–1316.
  • Murray CD. The physiological principle of minimum work applied to the angle of branching of arteries. J Gen Physiol. 1926;9:835–841.
  • Foin N, Sen S, Allegria E, et al. Maximal expansion capacity with current DES platforms: a critical factor for stent selection in the treatment of left main bifurcations? EuroIntervention. 2013;8:1315–1325.

• This study investigated the maximal expansion capacity of currently available drug-eluting stent platforms.

  • Foin N, Secco GG, Ghilencea L, et al. Final proximal post-dilatation is necessary after kissing balloon in bifurcation stenting. EuroIntervention. 2011;7:597–604.
  • Waksman R, Legutko J, Singh J, et al. FIRST: fractional flow reserve and intravascular ultrasound relationship study. J Am Coll Cardiol. 2013;61:917–923.
  • Park S-J, Ahn J-M, Kang S-J, et al. Intravascular ultrasound-derived minimal lumen area criteria for functionally significant left main coronary artery stenosis. JACC Cardiovasc Interv. 2014;7:868–874.
  • Kim J-S, Hong M-K, Ko Y-G, et al. Impact of intravascular ultrasound guidance on long-term clinical outcomes in patients treated with drug-eluting stent for bifurcation lesions: data from a Korean multicenter bifurcation registry. Am Heart J. 2011;161:180–187.
  • Ormiston JA, Webster MWI, Ruygrok PN, et al. Stent deformation following simulated side-branch dilatation: a comparison of five stent designs. Catheter Cardiovasc Interv. 1999;47:258–264.
  • Maeng M, Holm NR, Erglis A, et al. Long-term results after simple versus complex stenting of coronary artery bifurcation lesions: Nordic Bifurcation Study 5-year follow-up results. J Am Coll Cardiol. 2013;62:30–34.
  • Biondi-Zoccai G, Sheiban I, Servi S, et al. To kiss or not to kiss? Impact of final kissing-balloon inflation on early and long-term results of percutaneous coronary intervention for bifurcation lesions. Heart Vessels. 2013 [cited 2014 Aug 5]. Available from: http://link.springer.com/10.1007/s00380-013-0416-0.
  • Ge L, Airoldi F, Iakovou I, et al. Clinical and angiographic outcome after implantation of drug-eluting stents in bifurcation lesions with the crush stent technique: importance of final kissing balloon post-dilation. J Am Coll Cardiol. 2005;46:613–620.
  • Morino Y, Yamamoto H, Mitsudo K, et al. Functional formula to determine adequate balloon diameter of simultaneous kissing balloon technique for treatment of bifurcated coronary lesions: clinical validation by volumetric intravascular ultrasound analysis. Circ J Off J Jpn Circ Soc. 2008;72:886–892.
  • Authors/Task Force members, Windecker S, Kolh P, et al. 2014 ESC/EACTS guidelines on myocardial revascularization: the task force on myocardial revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). Developed with the special contribution of the European Association of Percutaneous Cardiovascular Interventions (EAPCI). Eur Heart J. 2014;35:2541–2619.
  • Kim W-J, Kim Y-H, Park D-W, et al. Comparison of single- versus two-stent techniques in treatment of unprotected left main coronary bifurcation disease. Catheter Cardiovasc Interv. 2011;77:775–782.
  • Song YB, Hahn J-Y, Yang JH, et al. Differential prognostic impact of treatment strategy among patients with left main versus non–left main bifurcation lesions undergoing percutaneous coronary intervention: results from the COBIS (Coronary Bifurcation Stenting) Registry II. JACC Cardiovasc Interv. 2014;7:255–263.
  • Pflederer T, Ludwig J, Ropers D, et al. Measurement of coronary artery bifurcation angles by multidetector computed tomography. Investig Radiol. 2006;41:793–798.
  • Oviedo C, Maehara A, Mintz GS, et al. Intravascular ultrasound classification of plaque distribution in left main coronary artery bifurcations: where is the plaque really located? Circ Cardiovasc Interv. 2010;3:105–112.
  • Džavík V, Colombo A. The absorb bioresorbable vascular scaffold in coronary bifurcations: insights from bench testing. JACC Cardiovasc Interv. 2014;7:81–88.

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