Catheter-directed thrombolysis for extensive iliofemoral deep vein thrombosis: review of literature and ongoing trials

References

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•• This paper described the results of an early randomized controlled trial, which compared the effectiveness and safety profiles of catheter-directed thrombolysis and anticoagulation versus anticoagulation alone in patients with iliofemoral deep vein thrombosis.

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•• This paper described the results of a recent randomized controlled trial, which compared the effectiveness and safety profiles of ultrasound-assisted catheter directed thrombolysis versus catheter-directed thrombolysis alone in patients with iliofemoral deep vein thrombosis.

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•• This paper described the results of a recent randomized controlled trial, which compared the effectiveness and safety profiles of catheter-directed thrombolysis and anticoagulation versus anticoagulation alone in patients with iliofemoral deep vein thrombosis.

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•• This paper described the results of a recent randomized controlled trial, which compared the effectiveness and safety profiles of catheter directed thrombolysis alone versus catheter-directed thrombolysis with angioplasty and/or stenting in patients with iliofemoral deep vein thrombosis.

• Engelberger RP, Spirk D, Willenberg T, et al. Ultrasound-assisted versus conventional catheter-directed thrombolysis for acute iliofemoral deep vein thrombosis. Circ Cardiovasc Interv. 2015;8(1). doi:10.1161/CIRCINTERVENTIONS.114.002027
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•• This paper described the rationale and design of an ongoing phase 3 randomized controlled trial, which compared the efficacy of three approaches of adjunctive catheter-directed thrombolysis with optimal standard therapy alone in patients with symptomatic proximal deep vein thrombosis.