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Editorial

Surrogate markers to assess new therapies for drug-resistant tuberculosis

Pages 163-168 | Published online: 10 Jan 2014

References

  • Wright A, Bai G, Barrera L et al. Emergence of Mycobacterium tuberculosis with extensive resistance to second-line drugs – worldwide, 2000–2004. Morb. Mortal. Wkly Rep.55(11), 301–305 (2006).
  • Nuermberger EL, Yoshimatsu T, Tyagi S et al. Moxifloxacin-containing regimens of reduced duration produce a stable cure in murine tuberculosis. Am. J. Respir. Crit. Care Med.170(10), 1131–1134 (2004).
  • Wallis RS. Reconsidering adjuvant immunotherapy for tuberculosis. Clin. Infect. Dis.41(2), 201–208 (2005).
  • Fleming TR, DeMets DL. Surrogate end points in clinical trials: are we being misled? Ann. Intern. Med.125(7), 605–613 (1996).
  • CAST II investigators. Effect of the antiarrhythmic agent moricizine on survival after myocardial infarction. N. Engl. J. Med.327(4), 227–233 (1992).
  • Mitchison DA. Modern methods for assessing the drugs used in the chemotherapy of mycobacterial disease. Soc. Appl. Bacteriol. Symp. Ser.25, S72–S80 (1996).
  • Mitchison DA. Assessment of new sterilizing drugs for treating pulmonary tuberculosis by culture at 2 months [letter]. Am. Rev. Respir. Dis.147(4), 1062–1063 (1993).
  • Yew WW, Chan CK, Chau CH et al. Outcomes of patients with multidrug-resistant pulmonary tuberculosis treated with ofloxacin/levofloxacin-containing regimens. Chest117(3), 744–751 (2000).
  • Priftin (rifapentine) package insert. In: Physician’s Desk Reference. Medical Economics, NJ, USA 1334–1338 (1999).
  • Benator D, Bhattacharya M, Bozeman L et al. Rifapentine and isoniazid once a week versus rifampicin and isoniazid twice a week for treatment of drug-susceptible pulmonary tuberculosis in HIV-negative patients: a randomised clinical trial. Lancet360(9332), 528–534 (2002).
  • Brindle R, Odhiambo J, Mitchison DA. Serial counts of Mycobacterium tuberculosis in sputum as surrogate markers of the sterilising activity of rifampicin and pyrazinamide in treating pulmonary tuberculosis. BMC Pulm. Med.1(1), 2 (2001).
  • Jindani AJ, Aber VR, Edwards EA, Mitchison DA. The early bactericidal activity of drugs in patients with pulmonary tuberculosis. Am. Rev. Respir. Dis.121, 939–949 (1980).
  • Davies GR, Brindle R, Khoo SH, Aarons LJ. Use of nonlinear mixed-effects analysis for improved precision of early pharmacodynamic measures in tuberculosis treatment. Antimicrob. Agents Chemother.50(9), 3154–3156 (2006).
  • Condos R, Rom WN, Schluger NW. Treatment of multidrug-resistant pulmonary tuberculosis with interferon-γ via aerosol. Lancet349(9064), 1513–1515 (1997).
  • Giosue S, Casarini M, Ameglio F et al. Aerosolized interferon-α treatment in patients with multi-drug-resistant pulmonary tuberculosis. Eur. Cytokine Netw.11(1), 99–104 (2000).
  • Suarez-Mendez R, Garcia-Garcia I, Fernandez-Olivera N et al. Adjuvant interferon γ in patients with drug - resistant pulmonary tuberculosis: a pilot study. BMC Infect. Dis.4(1), 44 (2004).
  • Koh WJ, Kwon OJ, Suh GY et al. Six-month therapy with aerosolized interferon-γ for refractory multidrug-resistant pulmonary tuberculosis. J. Korean Med. Sci.19(2), 167–171 (2004).
  • Dawson R, Condos R, Lucke W et al. Randomized clinical trial of aerosol or subcutaneous interferon γ plus DOTS versus DOTS alone for cavitary tuberculosis: early results. Am. J. Respir. Crit. Care Med.S2, A745 (2006).
  • Intermune Investor Relations Press Release. InterMune Enrolls First Patient in Phase III Trial in Multidrug-Resistant Tuberculosis. 8–1-2000.
  • Raju B, Hoshino Y, Kuwabara K et al. Aerosolized γ interferon (IFN-γ) induces expression of the genes encoding the IFN-γ-inducible 10-kilodalton protein but not inducible nitric oxide synthase in the lung during tuberculosis. Infect. Immun.72(3), 1275–1283 (2004).
  • Johnson BJ, Bekker LG, Rickman R et al. rhuIL-2 adjunctive therapy in multidrug resistant tuberculosis: a comparison of two treatment regimens and placebo. Tuber. Lung Dis.78(3–4), 195–203 (1997).
  • Johnson JL, Ssekasanvu E, Okwera A et al. Randomized trial of adjunctive interleukin-2 in adults with pulmonary tuberculosis. Am. J. Respir. Crit. Care Med.168, 185–191 (2003).
  • Ribeiro-Rodrigues R, Resende CT, Johnson JL et al. Sputum cytokine levels in patients with pulmonary tuberculosis as early markers of mycobacterial clearance. Clin. Diagn. Lab. Immunol.9(4), 818–823 (2002).
  • Barnes PF, Fong SJ, Brennan PJ, Twomey PE, Mazumder A, Modlin RL. Local production of tumor necrosis factor and IFN-γ in tuberculous pleuritis. J. Immunol.145, 149–154 (1990).
  • Bekker LG, Maartens G, Steyn L, Kaplan G. Selective increase in plasma tumor necrosis factor-α and concomitant clinical deterioration after initiating therapy in patients with severe tuberculosis. J. Infect. Dis.178(2), 580–584 (1998).
  • Wallis RS, Perkins M, Phillips M et al. Induction of the antigen 85 complex of M. tuberculosis in sputum: a determinant of outcome in pulmonary tuberculosis. J. Infect. Dis.178, 1115–1121 (1998).
  • Wallis RS, Phillips M, Johnson JL et al. Inhibition of INH-induced expression of M. tuberculosis antigen 85 in sputum: a potential surrogate marker in TB chemotherapy trials. Antimicrob. Agents Chemother.45(4), 1302–1304 (2001).
  • Aung H, Toossi Z, Wisnieski JJ et al. Induction of monocyte expression of TNFα by the 30-kD α antigen of M. tuberculosis, and synergism with fibronectin. J. Clin. Invest.98(5), 1261–1268 (1996).
  • Wallis RS, Kyambadde P, Johnson JL et al. A study of the safety, immunology, virology, and microbiology of adjunctive etanercept in HIV-1-associated tuberculosis. AIDS18(2), 257–264 (2004).
  • Mayanja-Kizza H, Jones-Lopez EC, Okwera A et al. Immunoadjuvant therapy for HIV-associated tuberculosis with prednisolone: a Phase II clinical trial in Uganda. J. Infect. Dis.191(6), 856–865 (2005).
  • Karakousis PC, Yoshimatsu T, Lamichhane G et al. Dormancy phenotype displayed by extracellular Mycobacterium tuberculosis within artificial granulomas in mice. J. Exp. Med.200(5), 647–657 (2004).
  • Wallis RS, Vinhas SA, Johnson JL et al. Whole blood bactericidal activity during treatment of pulmonary tuberculosis. J. Infect. Dis.187, 270–278 (2003).
  • Wallis RS, Song HY, Whalen C, Okwera A. TB chemotherapy: antagonism between immunity and sterilization. Am. J. Respir. Crit. Care Med.169(6), 771–772 (2004).
  • Heifets LB, Good RC. Current laboratory methods for the diagnosis of tuberculosis. In: Tuberculosis: Pathogenesis, Protection, and Control. Bloom BR (Ed.). ASM Press, DC, USA, 94 (1994).
  • Wallis RS, Patil S, Cheon SH et al. Drug tolerance in Mycobacterium tuberculosis. Antimicrob. Agents Chemother.43(11), 2600–2606 (1999).
  • Epstein MD, Schluger NW, Davidow AL, Bonk S, Rom WN, Hanna B. Time to detection of Mycobacterium tuberculosis in sputum culture correlates with outcome in patients receiving treatment for pulmonary tuberculosis. Chest113(2), 379–386 (1998).
  • Wallis RS, Perkins M, Phillips M et al. Predicting the outcome of therapy for pulmonary tuberculosis. Am. J. Respir. Crit. Care Med.161, 1076–1080 (2000).
  • Hasegawa N, Miura T, Ishizaka A, Yamaguchi K, Ishii K. Detection of mycobacteria in patients with pulmonary tuberculosis undergoing chemotherapy using MGIT and egg-based solid medium culture systems. Int. J. Tuberc. Lung Dis.6(5), 447–453 (2002).

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