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Review

Toponomics and neurotoponomics: a new way to medical systems biology

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Pages 361-369 | Published online: 09 Jan 2014

References

  • Schubert W. Cytomics in characterizing toponomes: towards the biological code of the cell. Cytometry A69, 209–211 (2006).
  • Schubert W. Breaking the biological code. Cytometry A71, 771–772 (2007).
  • Schubert W. Topological proteomics, Toponomics, MELK Technology. Adv. Biochem. Eng. Biotechnol.83, 189–209 (2003).
  • Schubert W, Bonnekoh B, Pommer AJ et al. Analyzing proteome topology and function by automated multidimensional fluorescence microscopy. Nat. Biotechnol.24, 1270–1278 (2006).
  • Friedenberger M, Bode M, Krusche A, Schubert W. Fluorescence detection of protein clusters in individual cells and tissue sections by using toponome imaging system: sample preparation and measuring procedures. Nat. Protoc.2, 2285–2294 (2007).
  • Murphy RF. Putting proteins on a map. Nat. Biotechnol.24, 1223–1224 (2006).
  • Zipf GK. Human Behavior and the Principle of Least Effort. Addison-Wesley, Cambridge, MS, USA (1949).
  • Schubert W. Multiple antigen – mapping microscopy of human tissue. In: Advances in Analytical Cellular Pathology. Burger G, Oberholzer M, Vooijs GP (Eds). Elsevier, Amsterdam 97–98 (1990).
  • Schubert W. Antigenic determinants of T Iymphocyte α/β receptor and other leukocyte surface proteins as differential markers of skeletal muscle regeneration: detection of spatially and timely restricted patterns by MAM microscopy. Eur. J. Cell Biol.58, 395–410 (1992).
  • Schubert W. Exploring molecular networks directly in the cell. Cytometry A69, 109–112 (2006).
  • Schubert W. A three symbol code for organized proteomes based on cyclical imaging of protein locations. Cytometry A71, 352–360 (2007).
  • Ecker RC, Rogojanu B, Streit M, Osterreicher K, Steiner GE. An improved method for discrimination of cell populations in tissue sections using microscopy-based multicolcor tissue cytometry. Cytometry A69(3), 119–123 (2006).
  • Ecker RC, Tarnok A. Cytomics goes 3D: toward tissomics. Cytometry A65(1), 1–3 (2005).
  • Mittag A, Lenz D, Gerstner AO, Tarnok A. Hyperchromatic cytometry principles for cytomics using slide based cytometry. Cytometry A69(7), 691–703 (2006).
  • Laffers W, Mittag A, Lenz D, Tarnok A, Gerstner AO. Iterative restaining as a privotal tool for n-color immunophenotyping by slide-based cytometry. Cytometry A69(3), 127–130 (2006).
  • Bedner E, Du L, Traganos F, Darzynkiewicz Z. Caffeine dissociates complexes between DNA and intercalating dyes: application for bleaching fluorochrome-stained cells for their subsequent restaining and analysis by laser scanning cytometry. Cytometry43(1), 38 (2001).
  • De Angelis L, Berghella L, Coletta M et al. Skeletal muscle progenitors originating from embryonic dorsal aorta coexpress endothelial and myogenic markers and contribute to postnatal muscle growth and regeneration. J. Cell Biol.147, 869–878 (1999).
  • Zheng B, Cao B, Crisan M et al. Prospective identification of myogenic endothelial cells in human skeletal muscle. Nat. Biotechnol.25, 1025–1034 (2007).
  • Sampaolesi M Blot S, D’Antona G, Granger N et al. Mesangioblast stem cells ameliorate muscle function in dystrophic dogs. Nature444, 552–553 (2006).
  • Torrente Y, Belicchi M, Marchesi C et al. Autologous transplantation of muscle-derived CD133+ stem cells in Duchenne patients. Cell Transplant.16, 563–577 (2007).
  • Conrad C, Boyman O, Tonel G et al. α1β1 integrin is crucial for accumulation of epidermal T cells and the development of psoriasis. Nat. Med.13, 836–842 (2007).
  • Nattkemper T, Ritter H, Schubert W. A neural classifyer enabling high-throughput topological analysis of Iymphocytes in tissue sections. IEEE Trans. Inf.Techn. Biomed.5, 138–149 (2001).
  • Nattkemper TW, Twellmann T, Schubert W, Ritter H. Human vs. machine: evaluation of fluorescence micrographs. Comput. Biol. Med.33, 31–43 (2003).
  • Dress A, Lokot T, Pustyl`nikov LD, Schubert W. Poisson numbers and poisson distributions in subset surprisology. Ann. Combinatorics8, 473–485 (2004).
  • Schubert W, Friedenberger M, Haars R, Nattkemper T, Ritter H. Automatic recognition of muscle invasive T cells expressing dipeptidyl-peptidase IV (CD26), and analysis of the associated cell surface phenotypes. J. Theoret. Med.4, 67–74 (2002).
  • Dress A, Lokot T, Schubert W, Serocka P. Two theorems about similarity maps. Ann. Combinatorics. (2008) (In Press).
  • Schubert W. Method of blocking cytotoxic activity in patients with amyotrophic lateral sclerosis using antibodies to FcγRIII. US patent No. 6,638,506 (first published as international patent application WO 99/29731) (1999).
  • Mohamed HA, Mosier DR, Zou LL et al. Immunoglobulin Fcgamma receptor promotes immunoglobulin uptake, immunoglobulin-mediated calcium release, and neurotransmitter release in motor neurons. J. Neurosci. Res.69, 110–116 (2002).
  • Schubert W, Masters CL, Beyreuther K. APP+ T Iymphocytes selectively sorted to endomysial tubes in polymyositis displace NCAM-expressing muscle fibers. Eur. J. Cell Biol.62, 333–342 (1992).
  • Haars R, Schneider A, Bode M, Schubert W. Secretion and differential localization of the proteolytic cleavage products Aβ40 and Aβ42 of the Alzheimer amyloid precursor protein in human fetal myogenic cells. Eur. J. Cell Biol.79, 400–406 (2000).
  • Schubert W. Polymositis, topological proteomics technology and paradigm for cell invasion dynamics. J. Theoret. Med.4, 67–74 (2002).
  • Ebert M, Müller-Ostermeyer F, Ademmer K et al. CD8+CD103+ cells analogous to intestinal intraepithelial Iymphocytes infiltrate the pancreas in chronic pancreatitis. Clin. Exp. Immunol.112, 21–26 (1998).
  • Ademmer K, Ebert M, Müller-Ostermeyer F et al. Effector T Iymphocyte subsets in human pancreatic cancer: detection of CD8+CD18+ cells and CD8+CD103+ cells by multi-epitope imaging. Am. J. Gastroenterol.11, 2141–2147 (1998).
  • Schubert W, Zimmermann K, Cramer K, Starzinski-Powitz A. Lymphocyte antigen Leul9 as a molecular marker of regeneration in human skeletal muscle. Proc. Natl Acad. Sci. USA86, 307–311 (1989).
  • Blitzer RD, Iyengar R, Landau EM. Postsynaptic signaling networks: cellular crogwheels underlying long-term plasticity. Biol. Psychiatry57, 113–119 (2005).
  • Malenka RC, Nicoll RA. Long-term potentiation – a decade of progress ? Science285, 1870–1874 (1999).
  • Lismann J. Long-term potentiation: outstanding questions and attempted synthesis. Philos. Philos. Trans. R. Soc. Lond., B, Biol. Sci.358, 829–842 (2003).
  • Greengard P. The neurobiology of slow synaptic transmission. Science294, 1024–1030 (2001).
  • Kandal ER. The molecular biology of memory storage: a dialogue between genes and synapses. Science294, 1030–1038 (2001).
  • Bennett GJ, Yie YK. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain33, 87–107 (1988).
  • Garry EM, Moss A, Delaney A et al. Neuropathic sensitisation of behavioral reflexes and spinal NMDA receptor/CaM kinase II interactions are disrupted in PSD-95 mutant mice. Curr. Biol.13, 321–328 (2003).
  • Bode M, Irmler M, Friedenberger. M, et al. Interlocking transcriptomics, proteomics and toponomics technologies for brain tissue analysis in murine hippocampus. Proteomics8(6), 1170–1178 (2008).
  • Bode M, Krusche A. Toponome Imaging System (TIS): imaging the proteome with functional resolution. Application note. Nat. Methods4, iii–iv (2007).

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