Growth factors and folliculogenesis in polycystic ovary patients

References

• Fortune JE, Cushman RA, Wahl CM, Kito S. The primordial to primary follicle transition. Mol. Cell. Endocrino.163(1–2), 53–60 (2000).
   Google Scholar
• Eppig JJ. Oocyte control of ovarian follicular development and function in mammals. Reproduction122(6), 829–838 (2001).
   PubMed Web of Science ®Google Scholar
• Erickson GF, Shimasaki S. The physiology of folliculogenesis: the role of novel growth factors. Fertil. Steri.76, 943–949 (2001).
   PubMed Web of Science ®Google Scholar
• Jonard S, Dewailly D. The follicular excess in polycystic ovaries, due to intra-ovarian hyperandrogenism, may be the main culprit for the follicular arrest. Hum. Reprod. Update10(2), 107–117 (2004).
   PubMed Web of Science ®Google Scholar
• Jonard S, Dewailly D, Pigny P. What are the determinants of the antral follicle number at ovarian ultrasonography (U/S) in PCOS? ESHRE Congress, Madrid, 29 June to 3 July 2003, oral communication, 0–119. Hum. Reprod.18(1), 42 (2003).
   Google Scholar
• Hull KL, Harvey S. Growth hormone: a reproductive endocrine-paracrine regulator? J. Reprod. Fertil.5, 175–182 (2000).
   Google Scholar
• Sirotkin AV, Makarevich AV. Growth hormone can regulate functions of porcine ovarian granulosa cells through the cAMP/protein kinase A system. Anim. Reprod. Sci.70, 111–126 (2002).
   Google Scholar
• Hull KL, Harvey S. Growth hormone: roles in female reproduction. J. Endocrinol.168, 1–23 (2001).
   PubMed Web of Science ®Google Scholar
• Ge Z, Miller E, Nicholson W et al. Insulin-like growth factor (IGF)-I and IGF binding proteins-2, -3, -4, -5 in porcine corpora lutea during the estrous cycle; evidence for inhibitory actions of IGFBP-3. Domest. Anim. Endocrinol.25, 183–197 (2003).
   Google Scholar
• Fortune JE, Rivera GM, Yang MY. Follicular development: the role of the follicular microenvironment in selection of the dominant follicle. Anim. Reprod. Sci.82–83, 109–126 (2004).
   Google Scholar
• Abd El Aal DE, Mohamed SA, Amine AF et al. Vascular endothelial growth factor and insulin-like growth factor-1 in polycystic ovary syndrome and their relation to ovarian blood flow. Eur. J. Obstet. Gynecol. Reprod. Biol.118(2), 219–224 (2005).
   PubMed Web of Science ®Google Scholar
• Greisen S, Flyvbjerg A, Ledet T et al. Regulation of insulin-like growth factor binding protein secretion by human granulosa luteal cells in a polycystic ovary-like environment. Fertil. Steril.78(1), 162–168 (2002).
   Google Scholar
• Druckmann R, Rohr DU. IGF-1 in gynaecology and obstetrics: update 2002. Maturitas41(Suppl. 1), S65–S83 (2002).
   PubMed Web of Science ®Google Scholar
• Balen A. The pathophysiology of polycystic ovary syndrome: trying to understand PCOS and its endocrinology. Best Pract. Res. Clin. Obstet. Gynaecol.18(5), 685–706 (2004).
   PubMed Web of Science ®Google Scholar
• Pawelczyk L, Spaczynski RZ, Banaszewska B et al. Metformin therapy increases insulin-like growth factor binding protein-1 in hyperinsulinemic women with polycystic ovary syndrome. Eur. J.Obstet. Gynecol. Reprod. Biol.113(2), 209–213 (2004).
   PubMed Web of Science ®Google Scholar
• Robinson CJ, Stringer SE. The splice variants of vascular endothelial growth factor (VEGF) and their receptors. J. Cell. Sci.114(Pt 5), 853–865 (2001).
   PubMed Web of Science ®Google Scholar
• Hornig C, Barleon B, Ahmad S et al. Release and complex formation of soluble VEGFR-1 from endothelial cells and biological fluids. Lab. Invest.80, 443–454 (2000).
   PubMed Web of Science ®Google Scholar
• Shin SY, Lee HJ, Ko DS et al. The regulators of VEGF expression in mouse ovaries. Yonsei Med. J.46(5), 679–686 (2005).
   Google Scholar
• Mattioli M, Barboni B, Turriani M et al. Follicle activation involves vascular endothelial growth factor production and increased blood vessel extension. Biol. Reprod.65(4), 1014–1019 (2001).
   PubMed Web of Science ®Google Scholar
• Stouffer RL, Martinez-Chequer JC, Molskness TA et al. Regulation and action of angiogenic factors in the primate ovary. Arch. Med. Res.32, 567–575 (2001).
   PubMed Web of Science ®Google Scholar
• Zimmermann RC, Xiao E, Husami N et al. Short-term administration of antivascular endothelial growth factor antibody in the late follicular phase delays follicular development in the rhesus monkey. J. Clin. Endocrinol. Metab.86(2), 768–772 (2001).
   Google Scholar
• Shimizu T, Jiang JY, Iijima K et al. Induction of follicular development by direct single injection of vascular endothelial growth factor gene fragments into the ovary of miniature gilts. Biology of Reproduction69, 1388–1393 (2003).
   PubMed Web of Science ®Google Scholar
• Gruemmer R, Motejlek K, Berghaus D et al. Regulation of soluble vascular endothelial growth factor receptor (sFlt-1/sVEGFR-1) expression and release in endothelial cells by human follicular fluid and granulosa cells. Reprod. Biol. Endocrinol.3, 57 (2005).
   Google Scholar
• Ferrara N, Frantz G, LeCouter J et al. Differential expression of the angiogenic factor genes vascular endothelial growth factor (VEGF) and endocrine gland-derived VEGF in normal and polycystic human ovaries. Am. J. Pathol.162(6), 1881–1893 (2003).
   PubMed Web of Science ®Google Scholar
• Loverro G, Vicino M, Lorusso F et al. Polycystic ovary syndrome: relationship between insulin sensitivity, sex hormone levels and ovarian stromal blood flow. Gynecol. Endocrinol.15(2), 142–149 (2001).
   PubMed Web of Science ®Google Scholar
• Li M, Bullock CM, Knauer DJ et al. Identification of two prokineticin cDNAs: recombinant proteins potently contract gastrointestinal smooth muscle. Mol. Pharmacol.59, 692–698 (2001).
   PubMed Web of Science ®Google Scholar
• LeCouter J, Kowalski J, Foster J et al. Identification of an angiogenic mitogen selective for endocrine gland endothelium. Nature412, 877–884 (2001).
   PubMed Web of Science ®Google Scholar
• LeCouter J, Lin R, Ferrara N. Endocrine gland-derived VEGF and the emerging hypothesis of organ-specific regulation of angiogenesis. Nat. Med.8, 913–917 (2002).
   PubMed Web of Science ®Google Scholar
• Kisliouk T, Levy N, Hurwitz A et al. Presence and regulation of endocrine gland vascular endothelial growth factor/prokineticin-1 and its receptors in ovarian cells. J. Clin. Endocrinol. Metab.88, 3700–3707 (2003).
   Google Scholar
• Ferrara N, LeCouter J, Lin R et al. EG-VEGF and Bv8: a novel family of tissue-restricted angiogenic factors. Biochimica et Biophysica Acta1654, 69–78 (2004).
   Google Scholar
• Visser JA, Themmen AP. Anti-Mullerian hormone and folliculogenesis. Mol. Cell. Endocrinol.234(1–2), 81–86 (2005).
   PubMed Web of Science ®Google Scholar
• Teixeira J, Maheswaran S, Donahoe PK. Müllerian-inhibiting substance: an instructive developmental hormone with diagnostic and possible therapeutic applications. Endocrinol. Rev.22, 657–674 (2001).
   PubMed Web of Science ®Google Scholar
• Durlinger ALL, Visser JA, Themmen APN. Regulation of ovarian function: the role of anti-Müllerian hormone. Reproduction124, 601–609 (2002).
   PubMed Web of Science ®Google Scholar
• Josso N, di Clemente N, Gouedard L. Anti-Mullerian hormone and its receptors. Mol. Cell. Endocrinol.179(1–2), 25–32 (2001).
   PubMed Web of Science ®Google Scholar
• di Clemente N, Josso N, Gouedard L et al. Components of the anti-Mullerian hormone signaling pathway in gonads. Mol. Cell. Endocrinol.211(1–2), 9–14 (2003).
   PubMed Web of Science ®Google Scholar
• Durlinger AL, Gruijters MJ, Kramer P. Anti-Mullerian hormone inhibits initiation of primordial follicle growth in the mouse ovary. Endocrinology143, 1076–1084 (2002).
   PubMed Web of Science ®Google Scholar
• Durlinger AL, Kramer P, Karels B. Control of primordial follicle recruitment by anti-Mullerian hormone in the mouse ovary. Endocrinology140, 5789–5796 (1999).
   PubMed Web of Science ®Google Scholar
• Durlinger AL, Gruijters MJ, Kramer P. Anti-Mullerian hormone attenuates the effects of FSH on follicle development in the mouse ovary. Endocrinology142, 4891–4899 (2001).
   PubMed Web of Science ®Google Scholar
• Seifer DB, MacLaughlin DT, Christian BP et al. Early follicular serum mullerian-inhibiting substance levels are associated with ovarian response during assisted reproductive technology cycles. Fertil. Steril.77, 468–471 (2002).
   PubMed Web of Science ®Google Scholar
• VanRooij IA, Broekmans FJ, Te Velde ER et al. Serum AMH levels: a novel measure of ovarian reserve. Hum. Reprod.17, 3065–3071 (2002).
   Google Scholar
• Fanchin R, Schonauer LM, Righini C et al. Serum AMH is more strongly related to ovarian follicular status than serum inhibin B, estradiol, FSH and LH on day 3. Hum. Reprod.18, 323–327 (2003).
   PubMed Web of Science ®Google Scholar
• Pigny P, Merlen E, Robert Y et al. Elevated serum level of anti-mullerian hormone (AMH) in polycystic ovary syndrome: relationship to the ovarian follicle excess and to the follicular arrest. J. Clin.Endocrinol. Metab.88, 5957–5962 (2003).
   PubMed Web of Science ®Google Scholar
• Cook CL, Siow Y, Brenner AG. Relationship between serum mullerian-inhibiting substance and other reproductive hormones in untreated women with polycystic ovary syndrome and normal women. Fertil. Steril.77, 141–146 (2002).
   PubMed Web of Science ®Google Scholar
• Laven JS, Mulders AG, Themmen AP. Anti-Mullerian hormone (AMH) serum concentrations in ormoovulatory and anovulatory women. J. Clin. Endocrinol. Metab.89, 318–323 (2004).
   PubMed Web of Science ®Google Scholar
• Ingraham HA, Hirokawa Y, Roberts LM et al. Autocrine and paracrine Mullerian inhibiting substance hormone signaling in reproduction. Recent Prog. Horm. Res.55, 53–67 (2000).
   PubMedGoogle Scholar
• Galloway SM, McNatty KP, Cambridge LM et al. Mutations in an oocyte-derived growth factor gene (BMP15) cause increased ovulation rate and infertililty in a dosage-sensitive manner. Nat. Genet.25, 279–283 (2000).
   PubMed Web of Science ®Google Scholar
• Teixeira FFL, Baracat EC, Lee TH et al. Aberrant expression of growth differentiation factor-9 in oocytes of women with polycystic ovary syndrome. J. Clin. Endocrinol. Metab.87, 1337–1344 (2005).
   Google Scholar
• Schneyer A, Fujiwara T, Fox J et al. Dynamic changes in the intrafollicular inhibin/activin/follistatin axis during human follicular development: relationship to circulating hormone concentrations. J. Clin. Endocrinol. Metab.85, 3319–3330 (2000).
   PubMed Web of Science ®Google Scholar
• Ginther OJ, Beg MA, Bergfelt DR et al. Follicle selection in monovular species. Biol. Reprod.65(3), 638–647 (2001).
   PubMed Web of Science ®Google Scholar
• Fujiwara T, Sidis Y, Welt C et al. Dynamics of inhibin subunit and follistatin mRNA during development of normal and polycystic ovary syndrome follicles. J. Clin. Endocrinol. Metab.86(9), 4206–4215 (2001).
   Google Scholar
• Welt CK, Taylor AE, Fox J et al. Follicular arrest in polycystic ovary syndrome is associated with deficient inhibin A and B biosynthesis. J. Clin. Endocrinol. Metab.90(10), 5582–5587 (2005).
   PubMed Web of Science ®Google Scholar
• Glister C, Groome NP, Knight PG. Bovine follicle development is associated with divergent changes in activin-A, inhibin-A and follistatin and the relative abundance of different follistatin isoforms in follicular fluid. J. Endocrinol.188(2), 215–225 (2006).
   Google Scholar
• Florio P, Luisi S, Marchetti P et al. Activin A stimulates insulin secretion in cultured human pancreatic islets. J. Endocrinol. Invest.23, 231–234 (2000).
   PubMed Web of Science ®Google Scholar
• Norman RJ, Milner CR, Groome NP et al. Circulating follistatin concentrations are higher and activin concentrations are lower in polycystic ovarian syndrome. Hum. Reprod.16(4), 668–672 (2001).
   PubMed Web of Science ®Google Scholar
• Eldar-Geva T, Spitz IM, Groome NP et al. Follistatin and activin A serum concentrations in obese and non-obese patients with polycystic ovary syndrome. Hum. Reprod.16(12), 2552–2556 (2001).
   PubMed Web of Science ®Google Scholar
• Shen ZJ, Chen XP, Chen YG. Inhibin B, activin A, and follistatin and the pathogenesis of polycystic ovary syndrome. Int. J. Gynaecol. Obstet.88(3), 336–337 (2005).
   Google Scholar
• Zhang YQ, Zhang H, Maeshima A et al. Up-regulation of the expression of activins in the pancreatic duct by reduction of the β-cell mass. Endocrinology143(9), 3540–3547 (2002).
   Google Scholar
• Nakayama M, Manabe N, Inoue N et al. Changes in the expression of tumor necrosis factor (TNF) α, TNFα receptor (TNFR) 2, and TNFR-associated factor 2 in granulosa cells during atresia in pig ovaries. Biol. Reprod.68, 530–535 (2003).
   Google Scholar
• Lanuza GM, Saragueta PE, Bussmann UA et al. Paradoxical effects of tumour necrosis factor α on rat granulosa cell DNA synthesis. Reprod. Fertil. Dev.14, 133–139 (2002).
   Google Scholar
• Prange-Kiel J, Kreutzkamm C, Wehrenberg U et al. Role of tumor necrosis factor in preovulatory follicles of swine. Biol. Reprod.65, 928–935 (2001).
   Google Scholar
• Okuda K, Sakumoto R. Multiple roles of TNF super family members in corpus luteum function. Reprod. Biol.Endocrinol.1, 95 (2003).
   Google Scholar
• Spicer LJ. Receptors for insulin-like growth factor-I and tumor necrosis factor α are hormonally regulated in bovine granulosa and thecal cells. Anim. Reprod. Sci.67, 45–58 (2001).
   Google Scholar
• Ghersevich S, Isomaa V, Vihko P. Cytokine regulation of the expression of estrogenic biosynthetic enzymes in cultured rat granulosa cells. Mol. Cell. Endocrinol.172, 21–30 (2001).
   Google Scholar
• Sakumoto R, Shibya M, Okuda K. Tumor necrosis factor-α (TNF-α.) inhibits progesterone and estradiol-17β production from cultured granulosa cells: presence of TNFα receptors in bovine granulosa and theca cells. J. Reprod. Dev.49(6), 441–449 (2003).
   Google Scholar
• Inoue N, Manabe N, Matsui T et al. Roles of tumor necrosis factor-related apoptosis-inducing ligand signaling pathway in granulosa cell apoptosis during atresia in pig ovaries. J. Reprod. Dev.49(4), 313–321 (2003).
   Google Scholar
• Araya AV, Aguirre A, Romero C et al. Evaluation of tumor necrosis factor α production in ex vivo short term cultured whole blood from women with polycystic ovary syndrome. Eur Cytokine Netw.13(4), 419–424 (2002).
   Google Scholar
• Gonzalez F, Rote NS, Minium J et al. In vitro evidence that hyperglycemia stimulates tumor necrosis factor-{α} release in obese women with polycystic ovary syndrome. J. Endocrinol.188(3), 521–529 (2006).
   PubMed Web of Science ®Google Scholar
• Murakoshi N, Miyauchi T, Kakinuma Y et al. Vascular endothelin-B receptor system in vivo plays a favorable inhibitory role in vascular remodeling after injury revealed by endothelin-B receptor-knockout mice. Circulation106, 1991–1998 (2002).
   PubMed Web of Science ®Google Scholar
• Nakas-Icindic E, Zaciragic A, Hadzovic A et al. Endothelin in health and disease. Bosn. J. Basic Med. Sci.4, 31–34 (2004).
   Google Scholar
• Diamanti-Kandarakis E, Spina G, Kouli C et al. Increased endothelin-1 levels in women with polycystic ovary syndrome and the beneficial effect of metformin therapy. J. Clin. Endocrinol. Metab.86(10), 4666–4673 (2001).
   PubMed Web of Science ®Google Scholar
• Ko C, Gieske MC, Al-Alem L et al. Endothelin-2 in ovarian follicle rupture. Endocrinology147(4), 1770–1779 (2006).
   PubMed Web of Science ®Google Scholar
• Artini PG, Monti M, Matteucci C et al. Vascular endothelial growth factor (VEGF) and basic fibrobast growth factor (bFGF) in the polycystic ovary syndrome during controlled ovarian hyperstimulation. Gynecol. Endocrinol. (2006) (In Press).
   Google Scholar
• Nilsson E, Parrott JA, Skinner MK. Basic fibroblast growth factor induces primordial follicle development and initiates folliculogenesis. Mol. Cell. Endocrinol.175(1–2), 123–130 (2001).
   PubMed Web of Science ®Google Scholar
• Skinner MK. Regulation of primordial follicle assembly and development. Hum. Reprod. Update11(5), 461–471 (2005).
   PubMed Web of Science ®Google Scholar
• Hammadeh ME, Fischer-Hammadeh C, Hoffmeister H et al. Fibroblast growth factor (FGF), intracellular adhesion molecule (sICAM-1) level in serum and follicular fluid of infertile women with polycystic ovarian syndrome, endometriosis and tubal damage, and their effect on ICSI outcome. Am. J. Reprod. Immunol.50(2), 124–130 (2003).
   Google Scholar
• Wang Y, Ge W. Cloning of epidermal growth factor (EGF) and EGF receptor from the zebrafish ovary: evidence for EGF as a potential paracrine factor from the oocyte to regulate activin/follistatin system in the follicle cells. Biol. Reprod.71(3), 749–760 (2004).
   Google Scholar
• Park JY, Su YQ, Ariga M et al. EGF-like growth factors as mediators of LH action in the ovulatory follicle. Science303(5658), 682–684 (2004).
   PubMed Web of Science ®Google Scholar