31
Views
1
CrossRef citations to date
0
Altmetric
Review

Does hormone treatment alter arterial properties in postmenopausal women?

, &
Pages 653-665 | Published online: 10 Jan 2014

References

  • Grodstein F, Manson JE, Colditz GA, Willett WC, Speizer FE, Stampfer MJ. A prospective, observational study of postmenopausal hormone therapy and primary prevention of cardiovascular disease. Ann. Intern. Med.33(12), 933–941 (2000).
  • Laurent S, Cockcroft J, Van Bortel L et al. Expert consensus document on arterial stiffness: methodological issues and clinical applications. Eur. Heart J.27(21), 2588–2605 (2006).
  • Mattace-Raso FU, van der Cammen TJ, Hofman A et al. Arterial stiffness and risk of coronary heart disease and stroke: the Rotterdam study. Circulation113(5), 657–663 (2006).
  • Redfield MM, Jacobsen SJ, Borlaug BA, Rodeheffer RJ, Kass DA. Age- and gender-related ventricular-vascular stiffening: a community-based study. Circulation112(15), 2254–2262 (2005).
  • Barrett-Connor E, Bush TL. Estrogen and coronary heart disease in women. JAMA265(14), 1861–1867 (1991).
  • Wenger NK, Speroff L, Packard B. Cardiovascular health and disease in women. N. Engl J. Med.329(4), 247–256 (1993).
  • Kannel WB, Hjortland MC, McNamara PM, Gordon T. Menopause and risk of cardiovascular disease: the Framingham study. Ann. Intern. Med.85, 447–452 (1976).
  • Tostes RC, Nigro D, Fortes ZB, Carvalho MH. Effects of estrogen on the vascular system. Braz. J. Med. Biol. Res.36(9), 1143–1158 (2003).
  • Orshal JM, Khalil RA. Gender, sex hormones, and vascular tone. Am. J. Physiol. Regul. Integr. Comp. Physiol.286(2), R233–R249 (2004).
  • Wolinsky H. Effects of estrogen and progestogen treatment on the response of the aorta of male rats to hypertension. Morphological and chemical studies. Circ. Res.30(3), 341–349 (1972).
  • Henneman DH. Effect of estrogen on in vivo and in vitro collagen biosynthesis and maturation in old and young female guinea pigs. Endocrinology83(4), 678–690 (1968).
  • Fischer GM, Bashey RI, Rosenbaum H, Lyttle CR. A possible mechanism in arterial wall for mediation of sex difference in atherosclerosis. Exp. Mol. Pathol.43(3), 288–296 (1985).
  • Fischer GM, Swain ML. Effects of estradiol and progesterone on the increased synthesis of collagen in atherosclerotic rabbit aortas. Atherosclerosis54(2), 177–185 (1985).
  • Fischer GM, Cherian K, Swain ML. Increased synthesis of aortic collagen and elastin in experimental atherosclerosis. Inhibition by contraceptive steroids. Atherosclerosis39(4), 463–467 (1981).
  • Fischer GM, Swain ML. Effect of sex hormones on blood pressure and vascular connective tissue in castrated and non-castrated male rats. Am. J. Physiol.232(6), H617–H621 (1977).
  • McCrohon JA, Adams MR, McCredie RJ et al. Hormone replacement therapy is associated with improved arterial physiology in healthy postmenopausal women. Clin. Endocrinol. (Oxford)45(4), 435–441 (1996).
  • Pepine CJ, Nichols WW, Pauly DF. Estrogen and different aspects of vascular disease in women and men. Circ. Res.99(5), 459–461 (2006).
  • Thompson J, Khalil RA. Gender differences in the regulation of vascular tone. Clin. Exp. Pharmacol. Physiol.30(1–2), 1–15 (2003).
  • Montague CR, Hunter MG, Gavrilin MA, Phillips GS, Goldschmidt-Clermont PJ, Marsh CB. Activation of estrogen receptor-α reduces aortic smooth muscle differentiation. Circ. Res.99(5), 477–484 (2006).
  • Chen Z, Yuhanna IS, Galcheva-Gargova Z, Karas RH, Mendelsohn ME, Shaul PW. Estrogen receptor α mediates the nongenomic activation of endothelial nitric oxide synthase by estrogen. J. Clin. Invest.103(3), 401–406 (1999).
  • Huang A, Sun D, Koller A, Kaley G. 17β-estradiol restores endothelial nitric oxide release to shear stress in arterioles of male hypertensive rats. Circulation101(1), 94–100 (2000).
  • Saitta A, Altavilla D, Cucinotta D et al. Randomized, double-blind, placebo-controlled study on effects of raloxifene and hormone replacement therapy on plasma NO concentrations, endothelin-1 levels, and endothelium-dependent vasodilation in postmenopausal women. Arterioscler. Thromb. Vasc. Biol.21(9), 1512–1519 (2001).
  • Farhat MY, Lavigne MC, Ramwell PW. The vascular protective effects of estrogen. FASEB J.10(5), 615–624 (1996).
  • Hayward CS, Kelly RP, Collins P. The roles of gender, the menopause and hormone replacement on cardiovascular function. Cardiovasc. Res.46(1), 28–49 (2000).
  • Khalil RA. Sex hormones as potential modulators of vascular function in hypertension. Hypertension46(2), 249–254 (2005).
  • Lebrun CE, van der Schouw YT, Bak AA et al. Arterial stiffness in postmenopausal women: determinants of pulse wave velocity. J. Hypertens.20(11), 2165–2172 (2002).
  • Enstrom I, Lidfeldt J, Lindholm LH, Nerbrand C, Pennert K, Samsioe G. Does blood pressure differ between users and non-users of hormone replacement therapy? The Women’s Health In the Lund Area (WHILA) study. Blood Press.11(4), 240–243 (2002).
  • Simon JA, Hsia J, Cauley JA et al. Postmenopausal hormone therapy and risk of stroke: The Heart and Estrogen–progestin Replacement Study (HERS). Circulation103(5), 638–642 (2001).
  • Shah SH, Alexander KP. Hormone replacement therapy for primary and secondary prevention of heart disease. Curr. Treat. Options Cardiovasc. Med.5(1), 25–33 (2003).
  • O’Rourke MF, Staessen JA, Vlachopoulos C, Duprez D, Plante GE. Clinical applications of arterial stiffness; definitions and reference values. Am. J. Hypertens.15(5), 426–444 (2002).
  • Mackenzie IS, Wilkinson IB, Cockcroft JR. Assessment of arterial stiffness in clinical practice. QJM95(2), 67–74 (2002).
  • Oliver JJ, Webb DJ. Noninvasive assessment of arterial stiffness and risk of atherosclerotic. Arterioscler. Thromb. Vasc. Biol.23(4), 554–566 (2003).
  • Nichols WW, O’Rourke MF. McDonald’s Blood Flow in Arteries: Theoretic, Experimental and Clinical Principles. (4th Edition). Edward Arnold, London, UK (1998).
  • Nichols WW, Edwards DG. Arterial elastance and wave reflection augmentation of systolic blood pressure: deleterious effects and implications for therapy. J. Cardiovasc. Pharmacol. Ther.6(1), 5–21 (2001).
  • O’Rourke MF, Seward JB. Central arterial pressure and arterial pressure pulse: new views entering the second century after Korotkov. Mayo Clin. Proc.81(8), 1057–1068 (2006).
  • Murgo JP, Westerhof N, Giolma JP et al. Aortic input impedance in normal man: relationship to pressure wave forms. Circulation62(1), 105–116 (1980).
  • Nichols WW, Singh BM. Augmentation index as a measure of peripheral vascular disease state. Curr. Opin. Cardiol.17(5), 543–551 (2002).
  • Nichols WW. Clinical measurement of arterial stiffness obtained from noninvasive pressure waveforms. Am. J. Hypertens.18(1 Pt 2), 3S–10S (2005).
  • O’Rourke MF, Nichols WW. Aortic diameter, aortic stiffness, and wave reflection increase with age and isolated systolic hypertension. Hypertension45(4), 652–658 (2005).
  • McEniery CM, Yasmin, Hall IR, Qasem A, Wilkinson IB, Cockcroft JR. Normal vascular aging: differential effects on wave reflection and aortic pulse wave velocity: the Anglo–Cardiff Collaborative Trial (ACCT). J. Am. Coll. Cardiol.46(9), 1753–1760 (2005).
  • Marchais SJ, Guerin AP, Pannier BM et al. Wave reflections and cardiac hypertrophy in chronic uremia. Influence of body size. Hypertension22(6), 876–883 (1993)
  • Boutouyrie P, Bussy C, Hayoz D et al. Local pulse pressure and regression of arterial wall hypertrophy during long-term antihypertensive treatment. Circulation101(22), 2601–2606 (2000).
  • Bank AJ, Wilson RF, Kubo SH et al. Direct effects of smooth muscle relaxation and contraction on in vivo human brachial artery elastic properties. Circ. Res.77, 1008–1016 (1995).
  • Bortolotto LA, Hanon O, Franconi G et al. The aging process modifies the distensibility of elastic but not muscular arteries. Hypertension34(4 Pt 2), 889–892 (1999).
  • Benetos A, Laurent S, Hoeks AP et al. Arterial alterations with aging and high blood pressure. A noninvasive study of carotid and femoral arteries. Arterioscler. Thromb.13(1), 90–97 (1993).
  • Laogun AA, Gosling RG. In vivo arterial compliance in man. Clin. Phys. Physiol. Meas.3(3), 201–212 (1982).
  • Smulyan H, Asmar RG, Rudnicki A, London GM, Safar ME. Comparative effects of aging in men and women on the properties of the arterial tree. J. Am. Coll. Cardiol.37(5), 1374–1380 (2001).
  • Waddell TK, Dart AM, Gatzka CD, Cameron JD, Kingwell BA. Women exhibit a greater age-related increase in proximal aortic stiffness than men. J. Hypertens.19(12), 2205–2212 (2001).
  • Ronnback M, Fagerudd J, Forsblom C, Pettersson-Fernholm K, Reunanen A, Groop PH. Altered age-related blood pressure pattern in Type 1 diabetes. Circulation110(9), 1076–1082 (2004).
  • Sonesson B, Hansen F, Stale H, Lanne T. Compliance and diameter in the human abdominal aorta – the influence of age and sex. Eur. J. Vasc. Surg.7(6), 690–697 (1993).
  • Nichols WW, O’Rourke MF. Aging: a physical perspective. In: Arterial Stiffness in Hypertension (Volume 23). Handbook of Hypertension. Safar ME, O’Rourke MF (Eds). Elsevier, NY, USA 379–397 (2006).
  • Staessen JA, van der Heijden-Spek JJ, Safar ME et al. Menopause and the characteristics of the large arteries in a population study. J. Hum. Hypertens.15(8), 511–518 (2001).
  • Karpanou EA, Vyssoulis GP, Papakyriakou SA, Toutouza MG, Toutouzas PK. Effects of menopause on aortic root function in hypertensive women. J. Am. Coll. Cardiol.28(6), 1562–1566 (1956).
  • Westendorp IC, Bots ML, Grobbee DE et al. Menopausal status and distensibility of the common carotid artery. Arterioscler. Thromb. Vasc. Biol.19(3), 713–717 (1999).
  • Izumi S, Muano T, Mori A, Kika G, Okuwaki S. Common carotid artery stiffness, cardiovascular function and lipid metabolism after menopause. Life Sci.78(15), 1696–1701 (2006).
  • McNulty M, Spiers P, McGovern E, Feely J. Aging is associated with increased matrix metalloproteinase-2 activity in the human aorta. Am. J. Hypertens.18(4 Pt 1), 504–509 (2005).
  • de Simone G, Roman MJ, Daniels SR et al. Age-related changes in total arterial capacitance from birth to maturity in a normotensive population. Hypertension29(6), 1213–1217 (1997).
  • London GM, Guerin AP, Pannier BM, Marchais SJ, Metivier F. Body height as a determinant of carotid pulse contour in humans. J. Hypertens.10(Suppl. 6), S93–S95 (1992).
  • Nichols WW, Avolio AP, O’Rourke MF. Ascending aortic impedance patterns in the kangaroo: their explanation and relation to pressure waveforms. Circ. Res.59(3), 247–255 (1986).
  • Schreiner PJ, Heiss G, Tyroler HA, Morrisett JD, Davis CE, Smith R. Race and gender differences in the association of Lp(a) with carotid artery wall thickness. The Atherosclerosis Risk in Communities (ARIC) study. Arterioscler. Thromb. Vasc. Biol.16(3), 471–478 (1996).
  • London GM, Guerin AP, Pannier B, Marchais SJ, Stimpel M. Influence of sex on arterial hemodynamics and blood pressure. Role of body height. Hypertension26(3), 514–519 (1995).
  • Hayward CS, Kelly RP. Gender-related differences in the central arterial pressure waveform. J. Am. Coll. Cardiol.30(7), 1863–7181 (1997).
  • Domanski MJ, Davis BR, Pfeffer MA, Kastantin M, Mitchell GF. Isolated systolic hypertension: prognostic information provided by pulse pressure. Hypertension34(3), 375–380 (1999).
  • Krumholz HM, Larson M, Levy D. Sex differences in cardiac adaptation to isolated systolic hypertension. Am. J. Cardiol.72(3), 310–313 (1993).
  • Shub C, Klein AL, Zachariah PK, Bailey KR, Tajik AJ. Determination of left ventricular mass by echocardiography in a normal population: effect of age and sex in addition to body size. Mayo Clin. Proc.69(3), 205–211 (1994).
  • Gatzka CD, Kingwell BA, Cameron JD et al. Gender differences in the timing of arterial wave reflection beyond differences in body height.J. Hypertens.19(12), 2197–2203 (2001).
  • Crews JK, Khalil RA. Antagonistic effects of 17 β-estradiol, progesterone, and testosterone on Ca2 and entry mechanisms of coronary vasoconstriction. Arterioscler. Thromb. Vasc. Biol.19(4), 1034–1040 (1999).
  • McGrath BP, Liang YL, Teede H, Shiel LM, Cameron JD, Dart A. Age-related deterioration in arterial structure and function in postmenopausal women: impact of hormone replacement therapy. Arterioscler. Thromb. Vasc. Biol.18(7), 1149–1156 (1998).
  • Sztejnsznajd C, Silva ME, Nussbacher A et al. Estrogen treatment improves arterial distensibility, fibrinolysis, and metabolic profile in postmenopausal women with Type 2 diabetes mellitus. Metabolism55(7), 953–959 (2006).
  • Vargas R, Wroblewska B, Rego A, Hatch J, Ramwell PW. Oestradiol inhibits smooth muscle cell proliferation of pig coronary artery. Br. J. Pharmacol.109(3), 612–617 (1993).
  • Kushwaha RS, Lewis DS, Carey KD, McGill HC Jr. Effects of estrogen and progesterone on plasma lipoproteins and experimental atherosclerosis in the baboon (Papio sp.). Arterioscler. Thromb.11(1), 23–31 (1991).
  • Manolio TA, Furberg CD, Shemanski L et al. Associations of postmenopausal estrogen use with cardiovascular disease and its risk factors in older women. The CHS Collaborative Research Group. Circulation88(5 Pt 1), 2163–2171 (1993).
  • Baron YM, Galea R, Brincat M. Carotid artery wall changes in estrogen-treated and -untreated postmenopausal women. Obstet. Gynecol.91(6), 982–986 (1998).
  • Westendorp IC, in ‘t Veld BA, Bots ML et al. Hormone replacement therapy and intima-media thickness of the common carotid. Stroke30(12), 2562–2567 (1999).
  • Liang YL, Teede H, Shiel LM et al. Effects of oestrogen and progesterone on age-related changes in arteries of postmenopausal women. Clin. Exp. Pharmacol. Physiol.24(6), 457–459 (1997).
  • Kawecka-Jaszcz K, Czarnecka D, Olszanecka A, Rajzer M, Jankowski P. The effect of hormone replacement therapy on arterial blood pressure and vascular compliance in postmenopausal women with arterial hypertension. J. Hum. Hypertens.16(7), 509–516 (2002).
  • Mihmanli V, Mihmanli I, Atakir K et al. Carotid intima–media thickness in surgical menopause: women who received HRT versus who did not. Maturitas42(1), 37–43 (2002).
  • Takahashi K, Tanaka E, Murakami M et al. Long-term hormone replacement therapy delays the age related progression of carotid intima-media thickness in healthy postmenopausal women. Maturitas49(2), 170–177 (2004).
  • Nabulsi AA, Folsom AR, Szklo M, White A, Higgins M, Heiss G. No association of menopause and hormone replacement therapy with carotid artery intima-media thickness. Atherosclerosis Risk in Communities (ARIC) Study Investigators. Circulation4(8), 1857–1863 (1996).
  • Sulistiyani Adelman SJ, Chandrasekaran A, Jayo J, St Clair RW. Effect of 17 α-dihydroequilin sulfate, a conjugated equine estrogen, and ethynylestradiol on atherosclerosis in cholesterol-fed rabbits. Arterioscler. Thromb. Vasc. Biol.15(7), 837–846 (1995).
  • Williams JK, Anthony MS, Honore EK et al. Regression of atherosclerosis in female monkeys. Arterioscler. Thromb. Vasc. Biol.15(7), 827–836 (1995).
  • Nagai Y, Earley CJ, Kemper MK, Bacal CS, Metter EJ. Influence of age and postmenopausal estrogen replacement therapy on carotid arterial stiffness in women. 41(1), 307–311 (1999).
  • Bui MN, Arai AE, Hathaway L, Waclawiw MA, Csako G, Cannon RO 3rd. Effect of hormone replacement therapy on carotid arterial compliance in healthy postmenopausal women. Am. J. Cardiol.90(1), 82–85 (2002).
  • Moreau KL, Donato AJ, Seals DR, DeSouza CA, Tanaka H. Regular exercise, hormone replacement therapy and the age-related decline in carotid arterial compliance in healthy women. Cardiovasc Res.57(3), 861–868 (2003).
  • Angerer P, Kothny W, Stork S, von Schacky C. Hormone replacement therapy and distensibility of carotid arteries in postmenopausal women: a randomized, controlled trial. J. Am. Coll. Cardiol.36(6), 1789–1796 (2000).
  • Rodriguez-Macias KA, Naessen T, Bostrom A, Bergqvist D. Arterial stiffness is not improved in long-term use of estrogen. Am. J. Obstet. Gynecol.186(2), 189–194 (2002).
  • Hulley S, Grady D, Bush T et al. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and estrogen/progestin Replacement Study (HERS) Research Group. JAMA280(7), 605–613 (1998).
  • Rajkumar C, Kingwell BA, Cameron JD et al. Hormonal therapy increases arterial compliance in postmenopausal women. J. Am. Coll. Cardiol.30(2), 350–356 (1997).
  • Waddell TK, Rajkumar C, Cameron JD, Jennings GL, Dart AM, Kingwell BA. Withdrawal of hormonal therapy for 4 weeks decreases arterial compliance in postmenopausal women. J. Hypertens.17(3), 413–418 (1999).
  • Teede HJ, Liang YL, Kotsopoulos D, Zoungas S, Cravent R, McGrath BP. A placebo-controlled trial of long-term oral combined continuous hormone replacement therapy in postmenopausal women: effects on arterial compliance and endothelial function. Clin. Endocrinol. (Oxford)55(5), 673–682 (2001).
  • Scuteri A, Lakatta EG, Bos AJ, Fleg JL. Effect of estrogen and progestin replacement on arterial stiffness indices in postmenopausal women. Aging (Milano)13(2), 122–130 (2001).
  • Miura S, Tanaka E, Mori A et al. Hormone replacement therapy improves arterial stiffness in normotensive postmenopausal women. Maturitas45(4), 293–298 (2003).
  • da Costa LS, de Oliveira MA, Rubim VS et al. Effects of hormone replacement therapy or raloxifene on ambulatory blood pressure and arterial stiffness in treated hypertensive postmenopausal women. Am. J. Cardiol.94(11), 1453–1456 (2004).
  • Tsioufis C, Tzioumis K, Dimitriadis K et al. Nondipping status does not attenuate the conjugated estrogen-induced impovement in aortic stiffness in postmenopausal women with untreated hypertension. Am. J. Hypertens.18(5 Pt 1), 607–611 (2005).
  • Sumino H, Ichikawa S, Kasama S et al. Different effects of oral conjugated estrogen and transdermal estradiol on arterial stiffness and vascular inflammatory markers in postmenopausal women. Atherosclerosis189(2), 436–442 (2006).
  • Luotola H. Blood pressure and hemodynamics in postmenopausal women during estradiol-17 β substitution. Ann. Clin. Res.15(Suppl. 38), S1–S121 (1983).
  • Scuteri A, Bos AJ, Brant LJ, Talbot L, Lakatta EG, Fleg JL. Hormone replacement therapy and longitudinal changes in blood pressure in postmenopausal women. Ann. Intern. Med.135(4), 229–238 (2001).
  • Williams B, Lacy PS, Thom SM et al. Differential impact of blood pressure-lowering drugs on central aortic pressure and clinical outcomes: principal results of the Conduit Artery Function Evaluation (CAFE) study. Circulation113(9), 1213–1225 (2006).
  • Hayward CS, Knight DC, Wren BG, Kelly RP. Effect of hormone replacement therapy on non-invasive cardiovascular haemodynamics. J. Hypertens.15(9), 987–993 (1997).
  • Hayward CS, Samaras K, Campbell L, Kelly RP. Effect of combination hormone replacement therapy on ambulatory blood pressure and arterial stiffness in diabetic postmenopausal women. Am. J. Hypertens.14(7 Pt 1), 699–703 (2001).
  • Hayward CS, Kalnins WV, Kelly RP. Acute effects of 17β-estradiol on ventricular and vascular hemodynamics in postmenopausal women. Am. J. Physiol. Heart Circ. Physiol.279(5), H2277–H2284 (2000).
  • Stefanadis C, Tsiamis E, Dernellis J, Toutouzas P. Effect of estrogen on aortic function in postmenopausal women. Am. J. Physiol.276(2 Pt 2), H658–H662 (1999).
  • Elsheikh M, Bird R, Casadei B, Conway GS, Wass JA. The effect of hormone replacement therapy on cardiovascular hemodynamics in women with Turner’s syndrome. J. Clin. Endocrinol. Metab.85(2), 614–618 (2000).
  • Tanaka H, DeSouza CA, Seals DR. Arterial stiffness and hormone replacement use in healthy postmenopausal women. J. Gerontol. A Biol. Sci. Med. Sci.53(5), M344–M346 (1998).
  • Tentolouris N, Christodoulakos G, Lambrinoudaki I, Mandalaki E, Panoulis C. Effect of hormone therapy on the elastic properties of the arteries in healthy postmenopausal women. J. Endocrinol. Invest.28(4), 305–311 (2005).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.