Relevance, pathogenesis and clinical implications of thyroid disorders in children with celiac disease

References

• Mooney PD, Hadjivassiliou M, Sanders DS. Coeliac disease. BMJ 2014;348:g1561
   PubMed Web of Science ®Google Scholar
• Kupfer SS, Jabri B. Pathophysiology of Celiac Disease. Gastrointest Endosc Clin N Am 2012;22:639-60
   PubMedGoogle Scholar
• Tanpowpong P, Broder-Fingert S, Katz AJ, Camargo CA. Age-related patterns in clinical presentations and gluten-related issues among children and adolescents with celiac disease. Clin Transl Gastroenterol 2012;3:e9
   Google Scholar
• Shan L, Molberg Ø, Parrot I, et al. Structural basis for gluten intolerance in celiac sprue. Science 2002;297:2275-9
   PubMed Web of Science ®Google Scholar
• Dieterich W, Ehnis T, Bauer M, et al. Identification of tissue transglutaminase as the autoantigen of celiac disease. Nat Med 1997;3:797-801
   PubMed Web of Science ®Google Scholar
• Dubé C, Rostom A, Sy R, et al. The prevalence of celiac disease in average-risk and at-risk Western European populations: a systematic review. Gastroenterology 2005;128:S57-67
   PubMed Web of Science ®Google Scholar
• Myléus A, Ivarsson A, Webb C, et al. Celiac disease revealed in 3% of Swedish 12-year-olds born during an epidemic. J Pediatr Gastroenterol Nutr 2009;49:170-6
   PubMed Web of Science ®Google Scholar
• Rampertab SD, Pooran N, Brar P, et al. Trends in the presentation of celiac disease. Am J Med 2006;119:355.e9-14
   PubMed Web of Science ®Google Scholar
• Telega G, Bennet TR, Werlin S. Emerging new clinical patterns in the presentation of celiac disease. Arch Pediatr Adolesc Med 2008;162:164-8
   PubMed Web of Science ®Google Scholar
• Husby S, Koletzko S, Korponay-Szabó IR, et al. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition guidelines for the diagnosis of coeliac disease. J Pediatr Gastroenterol Nutr 2012;54:136-60
   PubMed Web of Science ®Google Scholar
• Mustalahti K, Collin P, Sievänen H, et al. Osteopenia in patients with clinically silent coeliac disease warrants screening. The Lancet 1999;354:744-5
   PubMed Web of Science ®Google Scholar
• Zugna D, Richiardi L, Akre O, et al. A nationwide population-based study to determine whether coeliac disease is associated with infertility. Gut 2010;59:1471-5
   PubMed Web of Science ®Google Scholar
• Rubio-Tapia A, Hill ID, Kelly CP, American College of Gastroenterology. ACG clinical guidelines: diagnosis and management of celiac disease. Am J Gastroenterol 2013;108:656-76
   PubMed Web of Science ®Google Scholar
• Seyhan M, Erdem T, Ertekin V, Selimoğlu MA. The mucocutaneous manifestations associated with celiac disease in childhood and adolescence. Pediatr Dermatol 2007;24:28-33
   PubMed Web of Science ®Google Scholar
• Ludvigsson JF, Zingone F, Tomson T, et al. Increased risk of epilepsy in biopsy-verified celiac disease: a population-based cohort study. Neurology 2012;78:1401-7
   PubMed Web of Science ®Google Scholar
• Welander A, Sundelin B, Fored M, Ludvigsson JF. Increased risk of IgA nephropathy among individuals with celiac disease. J Clin Gastroenterol 2013;47:678-83
   PubMed Web of Science ®Google Scholar
• Iacono Lo O, Petta S, Venezia G, et al. Anti-tissue transglutaminase antibodies in patients with abnormal liver tests: is it always coeliac disease? Am J Gastroenterol 2005;100:2472-7
   PubMed Web of Science ®Google Scholar
• West J, Logan RFA, Smith CJ, et al. Malignancy and mortality in people with coeliac disease: population based cohort study. BMJ 2004;329:716-19
   PubMed Web of Science ®Google Scholar
• De Vries L, Bulvik S, Phillip M. Chronic autoimmune thyroiditis in children and adolescents: at presentation and during long-term follow-up. Arch Dis Child 2009;94:33-7
   PubMed Web of Science ®Google Scholar
• Collin P, Kaukinen K, Välimäki M, Salmi J. Endocrinological Disorders and Celiac Disease. Endocr Rev 2013;23:464-83
   Web of Science ®Google Scholar
• Størdal K, Bakken IJ, Surén P, Stene LC. Epidemiology of coeliac disease and comorbidity in Norwegian children. J Pediatr Gastroenterol Nutr 2013;57:467-71
   PubMed Web of Science ®Google Scholar
• Elfström P, Montgomery SM, Kämpe O, et al. Risk of Thyroid Disease in Individuals with Celiac Disease. J Clin Endocrinol Metab 2008;93:3915-21
   PubMed Web of Science ®Google Scholar
• Meloni A, Mandas C, Jores RD, Congia M. Prevalence of autoimmune thyroiditis in children with celiac disease and effect of gluten withdrawal. J Pediatr 2009;155:51-5 55.e1.
   PubMed Web of Science ®Google Scholar
• Van der Pals M, Ivarsson A, Norström F, et al. Prevalence of thyroid autoimmunity in children with celiac disease compared to healthy 12-year olds. Autoimmune Dis 2014;2014:417356
   PubMedGoogle Scholar
• Kalyoncu D, Urganci N. Antithyroid antibodies and thyroid function in pediatric patients with celiac disease. Int J Endocrinol 2015;2015:276575-4
   PubMed Web of Science ®Google Scholar
• Diamanti A, Ferretti F, Guglielmi R, et al. Thyroid autoimmunity in children with coeliac disease: a prospective survey. Arch Dis Child 2011;96:1038-41
   PubMed Web of Science ®Google Scholar
• Liu E, Lee H-S, Aronsson CA, et al. Risk of pediatric celiac disease according to HLA haplotype and country. N Engl J Med 2014;371:42-9
   PubMed Web of Science ®Google Scholar
• Dalton TA, Bennett JC. Autoimmune disease and the major histocompatibility complex: therapeutic implications. Am J Med 1992;92:183-8
   PubMed Web of Science ®Google Scholar
• Kaukinen K, Collin P, Mykkänen AH, et al. Celiac disease and autoimmune endocrinologic disorders. Dig Dis Sci 1999;44:1428-33
   PubMed Web of Science ®Google Scholar
• Badenhoop K, Dieterich W, Segni M, et al. HLA DQ2 and/or DQ8 is associated with celiac disease-specific autoantibodies to tissue transglutaminase in families with thyroid autoimmunity. Am J Gastroenterol 2001;96:1648-9
   PubMed Web of Science ®Google Scholar
• Hunt KA, McGovern DPB, Kumar PJ, et al. A common CTLA4 haplotype associated with coeliac disease. Eur J Hum Genet 2005;13:440-4
   PubMed Web of Science ®Google Scholar
• Chistiakov DA, Turakulov RI. CTLA-4 and its role in autoimmune thyroid disease. J Mol Endocrinol 2003;31:21-36
   PubMed Web of Science ®Google Scholar
• Schuppan D. Current concepts of celiac disease pathogenesis. Gastroenterology 2000;119:234-42
   PubMed Web of Science ®Google Scholar
• Antonelli A, Ferrari SM, Corrado A, et al. Autoimmune thyroid disorders. Autoimmun Rev 2015;14:174-80
   PubMed Web of Science ®Google Scholar
• Kumar V, Gutierrez-Achury J, Kanduri K, et al. Systematic annotation of celiac disease loci refines pathological pathways and suggests a genetic explanation for increased interferon-gamma levels. Hum Mol Genet 2015;24:397-409
   PubMed Web of Science ®Google Scholar
• Bjarnason I, Peters TJ, Veall N. A persistent defect in intestinal permeability in coeliac disease demonstrated by a 51Cr-labelled EDTA absorption test. The Lancet 1983;1:323-5
   PubMed Web of Science ®Google Scholar
• Fasano A. Intestinal zonulin: open sesame!. Gut 2001;49:159-62
   PubMed Web of Science ®Google Scholar
• Akobeng AK, Thomas AG. Systematic review: tolerable amount of gluten for people with coeliac disease. Aliment Pharmacol Ther 2008;27:1044-52
   PubMed Web of Science ®Google Scholar
• Kurppa K, Collin P, Sievänen H, et al. Gastrointestinal symptoms, quality of life and bone mineral density in mild enteropathic coeliac disease: a prospective clinical trial. Scand J Gastroenterol 2010;45:305-14
   PubMed Web of Science ®Google Scholar
• Silano M, Volta U, Vincenzi AD, et al. Collaborating Centers of the Italian Registry of the Complications of Coeliac Disease. Effect of a gluten-free diet on the risk of enteropathy-associated T-cell lymphoma in celiac disease. Dig Dis Sci 2008;53:972-6
   PubMed Web of Science ®Google Scholar
• Ventura A, Magazzù G, Greco L. Duration of exposure to gluten and risk for autoimmune disorders in patients with celiac disease. SIGEP Study Group for Autoimmune Disorders in Celiac Disease. Gastroenterol 1999;117:297-303
   PubMed Web of Science ®Google Scholar
• Ventura A, Neri E, Ughi C, et al. Gluten-dependent diabetes-related and thyroid-related autoantibodies in patients with celiac disease. J Pediatr 2000;137:263-5
   PubMed Web of Science ®Google Scholar
• Sategna Guidetti C, Solerio E, Scaglione N, et al. Duration of gluten exposure in adult coeliac disease does not correlate with the risk for autoimmune disorders. Gut 2001;49:502-5
   PubMed Web of Science ®Google Scholar
• Sategna Guidetti C, Volta U, Ciacci C, et al. Prevalence of thyroid disorders in untreated adult celiac disease patients and effect of gluten withdrawal: an Italian multicenter study. Am J Gastroenterol 2001;96:751-77
   PubMed Web of Science ®Google Scholar
• Cassio A, Ricci G, Baronio F, et al. Long-term clinical significance of thyroid autoimmunity in children with celiac disease. J Pediatr 2010;156:292-5
   PubMed Web of Science ®Google Scholar