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Reviews

Regulatory T-cells and preeclampsia: an overview of literature

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References

  • * Of interest
  • ** Of considerable interest
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studied the role of Treg cells in PE for the first time

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It was the first paper which offered the current definition of Treg

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This review article offered a very well classification of subjects

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  • Terness P, Kallikourdis M, Betz AG, et al. Tolerance signaling molecules and pregnancy: IDO, galectins, and the renaissance of regulatory T cells. Am J Reproductive Immunol ( New York, NY : 1989). 2007;58(3):238–254. Epub 2007 Aug 8.
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These three papers took the highest scores in our quality assessment

  • Miko E, Szereday L, Barakonyi A, et al. Immunoactivation in preeclampsia: Vdelta2+ and regulatory T cells during the inflammatory stage of disease. J Reprod Immunol. 2009;80(1–2):100–108. Epub 2009 Apr 28.
  • Toldi G, Rigo J Jr., Stenczer B, et al. Increased prevalence of IL-17-producing peripheral blood lymphocytes in pre-eclampsia. Am J Reproductive Immunol ( New York, NY 1989). 2011;66(3):223–229. Epub 2011 Feb 11.

These three papers took the highest scores in our quality assessment

  • Toldi G, Saito S, Shima T, et al. The frequency of peripheral blood CD4+ CD25high FoxP3+ and CD4+ CD25- FoxP3+ regulatory T cells in normal pregnancy and pre-eclampsia. Am J Reproductive Immunol ( New York, NY : 1989). 2012;68(2):175–180. Epub 2012 Apr19.

These three papers took the highest scores in our quality assessment

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  • Darmochwal-Kolarz D, Saito S, Tabarkiewicz J, et al. Apoptosis Signaling Is Altered in CD4(+)CD25(+)FoxP3(+) T Regulatory Lymphocytes in Pre-Eclampsia. Int J Mol Sci. 2012;13(6):6548–6560. Epub 2012 Jul 28.
  • Steinborn A, Haensch GM, Mahnke K, et al. Distinct subsets of regulatory T cells during pregnancy: is the imbalance of these subsets involved in the pathogenesis of preeclampsia? Clin Immunol ( Orlando, FL). 2008;129(3):401–412. Epub 2008 Sep 23.
  • Steinborn A, Schmitt E, Kisielewicz A, et al. Pregnancy‐associated diseases are characterized by the composition of the systemic regulatory T cell (Treg) pool with distinct subsets of Tregs. Clin Exp Immunol. 2012;167(1):84–98.
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  • Hafeez NA, Fouda Mel T, Abdel Gawad ER, et al. The role of regulatory T cells in preeclampsia. Egypt J Immunol. 2014;21(1):45–55. Epub 2014 Sep 11.
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