Using proteomics to identify targets of antiendothelial cell antibodies

References

• Petty RG, Pearson JD. Endothelium, the axis of vascular health and disease. J. Roy. Coll. Phys. London23, 92–102 (1989).
   PubMed Web of Science ®Google Scholar
• Meroni PL, Youinou P. Endothelial cell antibodies. In: Autoantibodies. Peter JB, Shoenfeld Y (Eds). Elsevier, Amsterdam, The Netherlands 245 (1996).
   Google Scholar
• Belizna C, Duijvestijn A, Hamidou M, Cohen Tervaert JW. Antiendothelial cell antibodies in vasculitis and connective tissue disease. Ann. Rheum. Dis.65, 1545–1550 (2006).
   PubMed Web of Science ®Google Scholar
• Bordron A, Revelen R, D’Arbonneau F et al. Functional heterogeneity of anti-endothelial cell antibodies. Clin. Exp. Immunol.124, 492–501 (2001).
   PubMed Web of Science ®Google Scholar
• Cines DB, Lyss AP, Reeber M, Bina M, DeHoratius RJ. Presence of complement-fixing anti-endothelial cell antibodies in systemic lupus erythematosus. J. Clin. Invest.73, 611–625 (1984).
   PubMed Web of Science ®Google Scholar
• Rosenbaum J, Pottinger BE, Woo P et al. Measurement and characterisation of circulating anti-endothelial cell IgG in connective tissue diseases. Clin. Exp. Immunol.72, 450–461 (1988).
   PubMed Web of Science ®Google Scholar
• Matsuda J, Gotoh M, Gohchi K, Kawasugi K, Tsukamoto M, Saitoh N. Antiendothelial cell antibodies to the endothelial hybridoma cell line (EAhy926) in systemic lupus erythematosus patients with antiphospholipid antibodies. Br. J. Haematol.97, 227–232 (1997).
   PubMedGoogle Scholar
• van Leeuwen EB, Wisman GB, Tervaert JW et al. An SV40 large T-antigen immortalized human umbilical vein endothelial cell line for anti-endothelial cell antibody detection. Clin. Exp. Rheumatol.19, 283–290 (2001).
   PubMedGoogle Scholar
• Belizna C, Cohen-Tervaert JW. Specificity, pathogenecity, and clinical value of antiendothelial cell antibodies. Semin. Arthritis Rheum.27, 98–109 (1997).
   PubMed Web of Science ®Google Scholar
• Revelen R, D’Arbonneau F, Guillevin L, Bordron A, Youinou P, Dueymes M. Comparison of cell-ELISA, flow cytometry and western blotting for the detection of antiendothelial cell antibodies. Clin. Exp. Rheumatol.20, 19–26 (2002).
   PubMed Web of Science ®Google Scholar
• Del Papa N, Guidali L, Sironi M et al. Anti-endothelial cell IgG antibodies from patients with Wegener’s granulomatosis bind to human endothelial cells in vitro and induce adhesion molecules expression and cytokine secretion. Arthritis Rheum.39, 758–766 (1996).
   PubMedGoogle Scholar
• Penning CA, Cunningham J, French MA et al. Antibody-dependent cellular cytotoxicity of human vascular endothelium in systemic sclerosis. Clin. Exp. Immunol.57, 548–556 (1984).
   PubMedGoogle Scholar
• Bordron A, Dueymes M, Levy Y et al. The binding of some human anti-endothelial cell antibodies induces endothelial cell apoptosis. J. Clin. Invest.101, 2029–2035 (1998).
   PubMed Web of Science ®Google Scholar
• Frohlich D, Spertini O, Moser R. The Fcγ receptor-mediated respiratory burst of rolling neutrophils to cytokine-activated, immune complexbearing endothelial cells depends on L-selectin but not on E-selectin. Blood91, 2558–2564 (1998).
   PubMedGoogle Scholar
• Papa ND, Raschi E, Moroni G et al. Anti-endothelial cell IgG fractions from systemic lupus erythematosus patients bind to human endothelial cells and induce a pro-adhesive and a pro-inflammatory inflammatoryphenotype in vitro. Lupus8, 423–429 (1999).
   PubMedGoogle Scholar
• Carvalho D, Savage CO, Isenberg D, Pearson JD. IgG anti-endothelial cell autoantibodies from patients with systemic lupus erythematosus or systemic vasculitis stimulate the release of two endothelial cell-derived mediators, which enhance adhesion molecule expression and leukocyte adhesion in an autocrine manner. Arthritis Rheum.42, 631–640 (1999).
   PubMed Web of Science ®Google Scholar
• Sgonc R, Gruschwitz MS, Dietrich H, Recheis H, Gershwin ME, Wick G. Endothelial cell apoptosis is a primary pathogenetic event underlying skin lesions in avian and human scleroderma. J. Clin. Invest.98, 785–792, (1996).
   PubMed Web of Science ®Google Scholar
• Florey OJ, Johns M, Esho OO, Mason JC, Haskard DO. Antiendothelial cell antibodies mediate enhanced leukocyte adhesion to cytokine-activated endothelial cells through a novel mechanism requiring cooperation between FcγRIIa and CXCR1/2. Blood109, 3881–3889 (2007).
   PubMedGoogle Scholar
• Cervera R, Khamashta MA, Font J et al. Anti-endothelial cell antibodies in patients with the antiphospholipid syndrome. Autoimmunity11, 1–6 (1991).
   PubMed Web of Science ®Google Scholar
• Cervera R, Khamashta MA, Hughes GRV. Antibodies to Endothelial Cells and Vascular Damage. CRC Press. FL, USA 83–84 (1993).
   Google Scholar
• Valesini G, Alessandri C, Celestino D, Conti F. Anti-endothelial antibodies and neuropsychiatric systemic lupus erythematosus. Ann. NY Acad. Sci.1069, 118–128 (2006).
   PubMed Web of Science ®Google Scholar
• Park M, Park Y, Jung SY, Lee KH, Lee S. Anti-endothelial cell antibodies and antiphospholipid antibodies in Takayasu’s arteritis: correlations of their titers and isotype distributions with disease activity. Clin. Exp. Rheum.24, S10–S16 (2006).
   PubMed Web of Science ®Google Scholar
• Kaneko M, Ono T, Matsubara T et al. Serological identification of endothelial antigens predominantly recognized in Kawasaki disease patients by recombinant expression cloning. Microbiol Immunol48, 703–711 (2004).
   PubMed Web of Science ®Google Scholar
• Lee KH, Chung HS, Kim HS et al. Human α-enolase form endothelial cells as a target antigen of anti-endothelial cell antibody in Behcet’s disease. Arthritis Rheum.48, 2025–2035 (2003).
   PubMed Web of Science ®Google Scholar
• Brasile L, Kremer J, Clarke J, Cerrilli J. Identification of an autoantibody to vascular endothelial cell-specific antigen in patients with systemic vasculitis. Am. J. Med.87, 74–80 (1987).
   Google Scholar
• Del Papa N, Meroni PL, Barcellini W et al. Antibodies to endothelial cells in primary vasculitis mediate in vitro endothelial cytotoxicity in the presence of normal peripheral blood mononuclear cells. Clin. Immunol. Immunopathol.63, 267–274 (1992).
   PubMedGoogle Scholar
• Ferraro G, Meroni PL, Tincani A et al. Anti-endothelial cell antibodies in patients with Wegener’s granulomatosis and micropolyarthritis. Clin. Exp. Immunol.79, 47–53 (1990).
   PubMed Web of Science ®Google Scholar
• Schoen FJ. Blood vessels. In:Robbins Pathologic Basis of Disease (5th Edition). Cotran RS, Kumar V, Robbins SL (Eds). Saunders, PA, USA 467–516 (1994).
   Google Scholar
• Heurkens AHM, Hiemstra PS, Lafeber GJM, Daha MR, Breedveld FC. Anti-endothelial cell antibodies in patients with rheumatoid arthritis complicated by vasculitits. Clin. Exp. Immunol.78, 7–12 (1989).
   PubMed Web of Science ®Google Scholar
• Vismara A, Meroni PL, Tincani A et al. Relationship between anti-cardiolipin and anti-endothelial cell antibodies in systemic lupus erythematosus. Clin. Lab. Immunol.17, 125–130 (1985).
   PubMedGoogle Scholar
• Westphal JR, Boerbooms ATh, Schalwijk CJM et al. Anti-endothelial cell antibodies in sera of patients with autoimmune diseases: comparison between ELISA and FACS analysis. Clin. Exp. Immunol.96, 444–449 (1994).
   PubMed Web of Science ®Google Scholar
• Direskeneli H, D’Cruz D, Khamashta AM, Hughes RV. Autoantibodies of against endothelial cells, extracellular matrix, and human collagen IV in patients with systemic vasculitis. Clin. Immunol. Immunopathol.70, 206–210 (1994).
   PubMedGoogle Scholar
• Gabriellu A, Montroni M, Rupoli S, Caniglia ML, De Lustro F, Danieli G. A retrospective study of antibodies against basement membrane antigens (type IV collagen and laminin) in patients with primary and secondary Raynaud’s phenomenon. Arthritis Rheum.31, 1433–1436 (1988).
   Google Scholar
• Mayet WJ, Csernok E, Szymkowiak C, Gross WL, Meyer zum Büschenfelde KH. Human endothelial cells express proteinase 3, the target antigen of anti-neutrophil cytoplasmic antibodies in Wegener’s granulomatosis. Blood82, 1221–1229 (1993).
   PubMed Web of Science ®Google Scholar
• Cohen Tervaert JW. The value of serial ANCA testing during follow-up studies in patients with ANCA-associated vasculitides. A review. J. Nephrol.9, 232–240 (1996).
   Google Scholar
• Meroni PL, Khamahta MA, Youinou P, Schoenfeld Y. Mosaic of anti-endothelial antibodies. Review of the first international workshop on anti-endothelial antibodies: clinical and pathological significance. Lupus4, 95–99 (1995).
   PubMedGoogle Scholar
• Del Papa N, Conforti G, Gambini D et al. Characterization of the endothelial surface proteins recognized by anti-endothelial cell antibodies in primary and secondary autoimmune vasculitis. Clin. Immunol. Immunopathol.70, 211–216 (1994).
   PubMedGoogle Scholar
• Van der Zee JM, Siegert CEH, De Vreede TA, Daha MR, Breedveld FC. Characterization of anti-endothelial cell antibodies in systemic lupus erythematosus. Clin. Exp. Immunol.84, 238–244 (1991).
   PubMed Web of Science ®Google Scholar
• Chan TM, Frampton G, Cameron JS. Identification of DNA-binding proteins on human umbilical vein endothelial cells plasma membrane. Clin. Exp. Immunol.91, 110–114 (1993).
   PubMedGoogle Scholar
• Youinou P. New target antigens for antiendothelial cell antibodies. Immunobiology210, 789–797 (2005).
   PubMed Web of Science ®Google Scholar
• Frampton G, Moriya S, Pearson JD et al. Identification of candidate endothelial cell autoantigens in systemic lupus erythematosus using a molecular cloning strategy: a role for ribosomal P protein P0 as an endothelial cell autoantigen. Rheumatology39, 1114–1120 (2000).
   PubMedGoogle Scholar
• Bruneel A, Labas V, Maillloux A et al. Proteomic study of human umbilical vein endothelial cells in culture. Proteomics3, 714–723 (2003).
   PubMed Web of Science ®Google Scholar
• Ha MK, Chung KY, Bang D, Park YK, Lee KH. Proteomic analysis of the proteins expressed by hydrogen peroxide treated cultured human dermal microvascular endothelial cells. Proteomics5, 1507–1519 (2005).
   PubMedGoogle Scholar
• Lee JH, Chung KY, Bang D, Lee KH. Searching for aging-related proteins in human dermal microvascular endothelial cells treated with anti-aging agents. Proteomics6, 1351–1361 (2006).
   PubMed Web of Science ®Google Scholar
• Ha MK. Cho JS, Baik O, Lee KH, Koo H, Chung KY. Caenorhabditis elegans as a screening tool for the endothelial cell-derived putative aging-related proteins detected by proteomic analysis. Proteomics6, 3339–3351 (2006).
   PubMedGoogle Scholar
• Cao MY, Dupriez VJ, Rider MH et al. Myelin protein Po as a potential autoantigen in autoimmune inner ear disease. FASEB J.10, 1635–1640 (1996).
   PubMed Web of Science ®Google Scholar
• Pohlner K, Portig I, Pankuweit S, Lottspeich F, Maisch B. Identification of mitochondrial antigens recognized by antibodies in sera of patients with idiopathic dilated cardiomyopathy by two-dimensional gel electrophoresis and protein sequencing. Am. J. Cardiol.80, 1040–1045 (1997).
   PubMed Web of Science ®Google Scholar
• Nakamura M, Tsutsumi K, Ooka S et al. Identification of β-tubulin isoform V as an autoantigen in allergic rhinitis by a proteomic approach. Microbiol. Immunol.48, 427–434 (2004).
   PubMedGoogle Scholar
• Xiang Y, Sekine T, Nakamura H et al. Proteomic surveillance of autoimmunity in osteoarthritis: identification of triosephosphate isomerase as an autoantigen in patients with osteoarthritis. Arthritis Rheum.50, 1511–1521 (2004).
   PubMed Web of Science ®Google Scholar
• Takasaki Y, Kaneda K, Matsushita M et al. Glyceraldehyde 3-phosphate dehydrogenase is a novel autoantigen leading autoimmune responses to proliferating cell nuclear antigen multiprotein complexes in lupus patients. Int. Immunol.16, 1295–1304 (2004).
   PubMed Web of Science ®Google Scholar
• Carlsson L, Ronquist G, Nilsson BO, Larsson A. Dominant prostasome immunogens for sperm-agglutinating autoantibodies of infertile men. J. Androl.25, 699–705 (2004).
   PubMedGoogle Scholar
• Hsu HC, Zhou T, Kim H et al. Production of a novel class of polyreactive pathogenic autoantibodies in BXD2 mice causes glomerulonephritis and arthritis. Arthritis Rheum.54, 343–355 (2006).
   PubMed Web of Science ®Google Scholar
• Huguet S, Labas V, Duclos-Vallee JC et al. Heterogeneous nuclear ribonucleoprotein A2/B1 identified as an autoantigen in autoimmune hepatitis by proteome analysis. Proteomics4, 1341–1345 (2004).
   PubMed Web of Science ®Google Scholar
• Canelle L, Bousquet J, Pionneau C et al. An efficient proteomics-based approach for the screening of autoantibodies. J. Immunol. Methods299, 77–89 (2005).
   PubMed Web of Science ®Google Scholar
• Zou L,Wu Y, Pei L et al. Identification of leukemia-associated antigens in chronic myeloid leukemia by proteomic analysis. Leuk. Res.29, 1387–1391 (2005).
   PubMedGoogle Scholar
• Ahn BY, Song ES, Cho YJ, Kwon OW, Kim JK, Lee NG. Identification of an anti-aldolase autoantibody as a diagnostic marker for diabetic retinopathy by immunoproteomic analysis. Proteomics6, 1200–1209 (2006).
   PubMed Web of Science ®Google Scholar
• Saulot V, Vittecoq O, Charlionet R et al. Presence of autoantibodies to the glycolytic enzyme α-enolase in sera from patients with early rheumatoid arthritis. Arthritis Rheum.46, 1196–1201 (2002).
   PubMed Web of Science ®Google Scholar
• Kinloch A, Tatzer V, Wait R et al. Identification of citrullinated αenolase as a candidate autoantigen in rheumatoid arthritis. Arthritis Res. Ther.7, 1421–1429 (2005).
   PubMed Web of Science ®Google Scholar
• Stulik J, Hernychova L, Porkertova S et al. Identification of new celiac disease autoantigens using proteomic analysis. Proteomics3, 951–956 (2003).
   PubMed Web of Science ®Google Scholar
• Dieude M, Senecal JL, Raymond Y. Induction of endothelial cell apoptosis by heat-shock protein 60-reactive antibodies from anti-endothelial cell autoantibody-positive systemic lupus erythematosus patients. Arthritis Rheum.50, 3221–3231 (2004).
   PubMed Web of Science ®Google Scholar
• Nahm D, Lee KH, Shin JY, Ye YM, Kang Y, Park HS. Identification of α-enolase as an autoantigen associated with severe asthma. J. Allergy Clin. Immunol.118, 376–381 (2006).
   PubMed Web of Science ®Google Scholar
• Pratesi F, Moscato S, Sabbatini A, Chimenti D, Bombardieri S, Migliorini P. Autoantibodies specific for α-enolase in systemic autoimmune disorders. J. Rheumatol.27, 109–115 (2000).
   PubMed Web of Science ®Google Scholar
• Pancholi V. Multifunctional α-enolase: its role in diseases. Cell Mol. Life Sci.58, 902–920 (2001).
   PubMed Web of Science ®Google Scholar
• Gitlits VM, Toh B, Sentry JW. Disease association, origin, and clinical relevance of autoantibodies to the glycolytic enzyme enolase. J. Invest. Med.49, 138–145 (2001).
   PubMedGoogle Scholar
• Fijak M, Iosub R, Schneider E et al. Identification of immunodominant autoantigens in rat autoimmune orchitis. J. Pathol.207, 127–138 (2005).
   PubMedGoogle Scholar
• Sinz A, Bantscheff M, Mikkat S et al. Mass spectrometric proteome analyses of synovial fluids and plasmas from patients suffering from rheumatoid arthritis and comparison to reactive arthritis or osteoarthritis. Electrophoresis23, 3445–3456 (2002).
   PubMed Web of Science ®Google Scholar
• Tilleman K, Van Beneden K, Dhondt A et al. Chronically inflamed synovium from spondyloarthropathy and rheumatoid arthritis investigated by protein expression profiling followed by tandem mass spectrometry. Proteomics5, 2247–2257 (2005).
   PubMed Web of Science ®Google Scholar
• Liao H, Wu J, Kuhn E et al. Use of mass spectrometry to identify protein biomarkers of disease severity in the synovial fluid and serum of patients with rheumatoid arthritis. Arthritis Rheum.50, 3792–3803 (2004).
   PubMed Web of Science ®Google Scholar
• de Seny D, Fillet M, Meuwis MA et al. Discovery of new rheumatoid arthritis biomarkers using the surface-enhanced laser desorption/ionization time-of-flight mass spectrometry ProteinChip approach. Arthritis Rheum.52, 3801–3812 (2005).
   PubMed Web of Science ®Google Scholar
• Tomosugi N, Kitagawa K, Takahashi N, Sugai S, Ishikawa I. Diagnostic potential of tear proteomic patterns in Sjogren’s syndrome. J. Proteome Res.4, 820–825 (2005).
   PubMed Web of Science ®Google Scholar
• Hunt DF, Yates JR, Shabanowitz J, Winston S, Hauer CR. Proc. Natl Acad. Sci. USA83, 6233–6237 (1986).
   PubMed Web of Science ®Google Scholar
• Marcotte EM. How do shotgun proteomics algorithms identify proteins? Nat. Biotech.7, 755–757 (2007).
   Google Scholar
• Gavin AC, Aloy P, Grandi P et al. Proteome survey reveals modularity of the yeast cell machinery. Nature440, 631–636 (2006).
   PubMed Web of Science ®Google Scholar
• Krogan NJ, Cagney G, Yu H et al. Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature440, 637–643 (2006).
   PubMed Web of Science ®Google Scholar
• Foster LJ, de Hoog CL, Zhang Y et al. A mammalian organelle map by protein correlation profiling. Cell125, 187–199 (2006).
   PubMed Web of Science ®Google Scholar
• Decramer S, Wittke S, Mischak H et al. Predicting the clinical outcome of congenital unilateral uteropelvic junction obstruction in newborn by urinary proteome analysis. Nat. Med.12, 398–400 (2006).
   PubMed Web of Science ®Google Scholar
• Matsuda J, Saitoh N, Gohchi K et al. Anti-annexin V antibody in systemic lupus erythematosus patients with lupus anticoagulant and/or anticardiolipin antibody. Am. J. Hematol.47, 56–58 (1994).
   PubMed Web of Science ®Google Scholar
• Tripathy NK, Sinha N., Nityanand S. Anti-annexin V antibodies in Takayasu’s arteritis: prevalence and relationship with disease activity. Clin. Exp. Immunol.134, 360–364 (2003).
   PubMedGoogle Scholar
• Wheeler CH, Collins A, Dunn MJ, Crisp SJ, Yacoub MH, Rose ML. Characterization of endothelial antigens associated with transplant-associated coronary artery disease. J. Heart Lung Transplant.14, 188–197 (1995).
   Google Scholar
• Margutti P, Delunardo F, Sorice M et al. Screening of a HUVEC cDNA library identifies actin as a candidate autoantigen associated with carotid atherosclerosis. Clin. Exp. Immunol.137, 209–215 (2004).
   PubMedGoogle Scholar
• Yoshio T, Masuyama J, Kano S. Antiribosomal PO protein antibodies react with the surface of human umbilical vein endothelial cells. J. Rheumatol.23, 1311–1312 (1996).
   PubMedGoogle Scholar
• Alderuccio F, Barnett AJ, Campbell JH, Pederson JS, Toh BH. Scl-95/100: doublet of endothelial marker autoantigens in progressive systemic sclerosis. Clin. Exp. Immunol.64, 94–100 (1986).
   PubMedGoogle Scholar