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Special Report

Potential use of aromatase inhibitors in gynecology

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Pages 41-47 | Published online: 10 Jan 2014

References

  • Simpson ER, Davis SR. Mini-review: aromatase and the regulation of estrogen biosynthesis – some new perspectives. Endocrinology142, 4589–4594 (2001).
  • Holzer H, Casper R, Tulandi T. A new era in ovulation induction. Fertil. Steril.85, 277–284 (2006).
  • Simpson ER, Mahendroo MS, Means D et al. Aromatase cytochrome P450, the enzyme responsible for estrogen biosynthesis. Endocr. Rev.15, 342–355 (1994).
  • Michael MD, Michael LF, Simpson ER. A CRE-like sequence that binds CREB and contributes to cAMP dependent regulation of the proximal promoter of the human aromatase P450 (CYP19) gene. Mol. Cell Endocrinol.134, 147–156 (1997).
  • Zhao Y, Mendelson CR, Simpson ER. Characterisation of the sequences of the human CYP19 (aromatase) gene that mediate regulation by glucocorticoids in adipose stromal cells and fetal hepatocytes. Mol. Endocrinol.9, 340–349 (1995).
  • Agarwal VR, Bulun SE, Leitch M, Rohrick R, Simpson ER. Use of alternative promotors to express the aromatase cytochrome P450 enzyme (CYP19) gene in breast adipose tissues of cancer free and breast cancer patients. J. Clin. Endocrinol. Metab.81, 3843–3849 (1996).
  • Cole PA, Robinson CH. Mechanism and inhibition of cytochrome P-450 aromatase. J. Med. Chem.3, 2933–2944 (1990).
  • Nabholtz JM, Buzdar A, Pollak M et al. Anastrozole is superior to tamoxifen as first-line therapy for advanced breast cancer in postmenopausal women: results of a North American multicenter randomised trial. Arimidex Study Group. J. Clin. Oncol.18, 3758–3767 (2000).
  • Colussi DM, Parisot CY, Lefevre GY. Plasma protein binding of letrozole, a new nonsteriodal aromatase enzyme inhibitor. J. Clin. Pharmacol.38, 727–735 (1998).
  • Pfister HC, Martoni A, Zamagni C et al. Effect of age and single versus multiple dose pharmacokinetics of letrozole in breast cancer patients. Biopharm. Drug Dispos.22, 191–197 (2001).
  • Haynes BP, Dowsett M, Miller WR, Dixon JM, Bhatnagar AS. The pharmacology of letrozole. J. Ster. Biochem. Mol. Biol.87, 35–45 (2003).
  • Geisler J, Haynes B, Anker G, Dowsett M, Lonning PE. Influence of letrozole and anastrozole on total body aromatisation and plasma estrogen levels in post menopausal breast cancer patients evaluated in a randomised cross over study. J. Clin. Oncol.20, 751–757 (2002).
  • Evans TR, Di Salle E, Ornati G et al. Phase I and endocrine study of exemestane (FCE 24304), a new aromatase inhibitor in postmenopausal women. Cancer Res.52, 5933–5939 (1992).
  • Geisler J, King N, Anker G et al. In vivo inhibition of aromatisation by exemestane, a novel irreversible aromatase inhibitor, in postmenopausal breast cancer patients. Clin. Cancer Res.4, 2089–2093 (1998).
  • Bonhoff AJ, Nether OG, Johannisson E. Effects of clomiphene citrate on endometrial structure in infertile women. Hum. Reprod.11, 844–849 (1996).
  • Gonan Y, Casper RF. Sonographic determination of an adverse effect of clomiphene citrate on endometrial growth. Hum. Reprod.5, 670–674 (1990).
  • Randall JM, Templeton A. Cervical mucus score and in vitro sperm mucus interaction in spontaneous and clomiphene citrate cycles. Fertil. Steril.56, 465–468 (1991).
  • Weil S, Vondole K, Sou J, Boudy C. Androgen and follicle stimulating hormone interactions in primate ovarian follicle development. J. Clin. Endocrinol. Metab.84, 2951–2956 (1999).
  • Fisher SA, Reid RL, Van Vugt DA, Casper RF. A randomised double blind comparison of the effects of clomiphene citrate and the aromatase inhibitor letrozole on ovulatory function in normal women. Fertil. Steril.78, 280–285 (2002).
  • Mitwally MF, Casper RF. Aromatase inhibition: a novel method of ovulation induction in women with polycystic ovarian syndrome. Reprod. Technol.10, 244–247 (2000).
  • Mitwally MF, Casper RF. Use of an aromatase inhibitor for ovulation induction in patients with an inadequate response to clomiphene citrate. Fertil. Steril.75, 30530–30539 (2000).
  • Cortinez A, De Carvalho I, Vantman D et al. Hormonal profile and endometrial morphology in letrozole controlled ovarian hyperstimulation in ovulatory infertile patients. Fertil. Steril.83(1), 110–115 (2005).
  • Al-Omari WR, Sulman WR, Al-Hadithi N. Comparison of two aromatase inhibitors in women with clomiphene-resistant polycystic ovary syndrome. Int. J. Gynaecol. Obstet.85, 289–291 (2004).
  • Sammour A, Biljan MM, Tan SL, Tulandi T. Prospective randomised trial comparing the effects of letrozole (LE) and clomiphene citrate (CC) on follicular development, endometrial thickness and pregnancy rate in patients undergoing super-ovulation prior to intrauterine insemination. Fertil. Steril.76(Suppl. 1), S110 (2001) (Abstract).
  • Mitwally MF, Casper RF. Aromatase inhibition reduces gonadotropin dose required for controlled ovarian stimulation in women with unexplained infertility. Hum. Reprod.18, 1588–1597 (2003).
  • Healey S, Tan SL, Tulandi T, Biljan M. Effects of letrozole on superovulation with gonadotropins in women undergoing intrauterine insemination. Fertil. Steril.80, 1325–1329 (2004).
  • Al-Fadhli R, Sylvestre C, Buckett W, Tan SL, Tulandi T. A randomized trial of superovulation with two different doses of letrozole. Fertil. Steril.85, 161–164 (2006).
  • Biljan MM, Hemmings R, Brassard N. The outcome of 150 babies following the treatment with letrozole or letrozole and gonadotropins. Oral presentation ASRM 2005. Fertil. Steril.84(Suppl. 1), 0–231 (2005).
  • Tulandi T, Martin J, Al-Fadhli R et al. Congenital malformations among 911 newborns conceived after infertility treatment with letrozole or clomiphene citrate. Fertil. Steril.85(6), 1761–1765 (2006).
  • Buttram VC, Reiter RC. Uterine myomata: etiology, symptomatology and management. Fertil. Steril.36, 433–445 (1981).
  • Stewart EA. Uterine fibroids. Lancet357, 293–298 (2001).
  • Felberbaum RE, Germer U, Ludwig M et al. Treatment of uterine fibroids with a slow release formulation of the gonadotropin releasing hormone antagonist Cetrorelix. Hum. Reprod.13, 660–668 (1998).
  • De Leo V, Morgante G, Lanzetta D, D’Antona D, Bertieri RS. Danazol administration after gonadotropin releasing hormone analog reduces rebound of uterine myomas. Hum. Reprod.12, 357–360 (1997).
  • Coutinho EM, Goncalves MT. Long term treatment of myomas with gestrinone. Fertil. Steril.51, 939–946 (1989).
  • Murphy AA, Kettel LM, Morales AJ, Roberts VJ, Yen SS. Regression of uterine myomata in response to the antiprogesterone RU 486. J. Clin. Endocrinol. Metab.76, 513–517 (1993).
  • Sumitani H, Shozu T, Segawa HJ, Yang K, Murakami M. In situ estrogen synthesized by aromatase P450 in uterine myoma cells promotes cell growth probably via an autocrine/intracrine mechanism. Endocrinology141, 3852–3861 (2000).
  • Bulun SE, Simpson ER, Word RA. Expression of the CYP19 gene and its product aromatase cytochrome P450 in human myoma tissues and cells in culture. J. Clin. Endocrinol. Metab.78, 736–743 (1994).
  • Shozu M, Murakami K, Segawa T, Kasai T, Inoue M. Successful treatment of symptomatic uterine myoma with a non-steroidal aromatase inhibitor in a premenopausal woman. Fertil. Steril.79, 628–631 (2003).
  • Vessey MP, Villard-Mackintosh L, Painter R. Epidemiology of endometriosis in women attending family planning clinics. Br. Med. J.306, 182–184 (1993).
  • Zeitoun K, Takayama K, Michael MD, Bulun SE. Stimulation of aromatase promoter II activity in endometriosis and its inhibition in endometrium are regulated by competitive binding of steroidogenic factor-1 and chicken ovalbumin upstream promoter transcription factor to the same cis-acting element. Mol. Endocrinol.13, 239–253 (1999).
  • Noble LS, Takayam K, Zeitoun KM et al. Prostaglandin stimulates aromatase expression in endometriosis derived stromal cells. J. Clin. Endocrinol. Metab.82, 600–606 (1997).
  • Bulun SE, Imir G, Utsunomiya H et al. Aromatase in endometriosis and uterine myomata. J. Steroid Biochem. Mol. Biol.95, 57–62 (2005).
  • Waller KG, Shaw RW. Gonadotropin-releasing hormone analogs for the treatment of endometriosis: long-term follow-up. Fertil. Steril.59, 511–515 (1993).
  • Bulun SE, Zeitoun K, Takayama K et al. Estrogen production in endometriosis and use of aromatase inhibitors to treat endometriosis. Endocr. Relat. Cancer6, 293 (1999).
  • Takayama K, Zeitoun K, Gunby RT et al. Treatment of severe postmenopausal endometriosis with an aromatase inhibitor. Fertil. Steril.69, 709 (1998).
  • Razzi S, Fava A, Sartini A et al. Treatment of severe recurrent endometriosis with an aromatase inhibitor in a young ovariectomised woman. BJOG111, 182–184 (2004).
  • Ailawadi RK, Jobanputra S, Kataria M et al. Treatment of endometriosis and chronic pelvic pain with letrozole and norethindrone acetate: a pilot study. Fertil. Steril.81, 290–296 (2004).
  • Soysal S, Sysal ME, Ozer S, Gul N, Gezgin T. The effects of post-surgical administration of goserelin plus anastozole compared to goserelin alone in patients with severe endometriosis: a prospective randomised trial. Hum. Reprod.19, 160–167 (2004).
  • Simpson ER. Aromatase: biologic relevance of tissue-specific expression. Semin. Reprod. Med.22, 11–23 (2004).

Website

  • Health Canada. Congenital anomalies in Canada – a perinatal health report (2002). www.phac-aspc.gc.ca/publicat/cac-acc02

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