Proteomic biomarkers of adverse pregnancy outcome in preterm birth: a theranostics opportunity

References

• Martin JA, Hamilton BE, Sutton PD. Births: final data for 2004. National Vital Statistics Reports55, 1–101 (2006).
   Google Scholar
• Flores-Santos R, Hernandez-Cabrera MA, Hernandez-Herrera RJ. Screening for retinopathy of prematurity: results of a 7-year study of underweight newborns. Arch. Med. Res.38, 440–443 (2007).
   PubMed Web of Science ®Google Scholar
• Patra K, Wilson-Costello D, Taylor HG. Grades I–II intraventricular hemorrhage in extremely low birth weight infants: effects on neurodevelopment. J. Pediatr.149, 169–173 (2006).
   PubMed Web of Science ®Google Scholar
• Hintz SR, Kendrick DE, Vohr BR; National Institute of Child Health and Human Development Neonatal Research Network. Changes in neurodevelopmental outcomes at 18–22 months’ corrected age among infants of less than 25 weeks’ gestational age born in 1993–1999. Pediatrics115, 1645–1651 (2005).
   PubMed Web of Science ®Google Scholar
• Vincer MJ, Allen AC, Joseph KS. Increasing prevalence of cerebral palsy among very preterm infants: a population-based study. Pediatrics118, E1621–E1626 (2006).
   PubMed Web of Science ®Google Scholar
• Bhandari A, Bhandari V. Pathogenesis, pathology and pathophysiology of pulmonary sequelae of bronchopulmonary dysplasia in premature infants. Front. Biosci.8, E370–E380 (2003).
   Web of Science ®Google Scholar
• Clements KM, Barfield WD, Ayadi MF. Preterm birth-associated cost of early intervention services: an analysis by gestational age. Pediatrics119, e866–e874 (2007).
   PubMed Web of Science ®Google Scholar
• Green NS, Damus K, Simpson JL; March of Dimes Scientific Advisory Committee on Prematurity. Research agenda for preterm birth: recommendations from the March of Dimes. Am. J. Obstet. Gynecol.193, 626–635 (2005).
   PubMed Web of Science ®Google Scholar
• Berghella V, Owen J, MacPherson C. Natural history of cervical funneling in women at high risk for spontaneous preterm birth. Obstet. Gynecol.109, 863–869 (2007).
   PubMed Web of Science ®Google Scholar
• Klebanoff M, Searle K. The role of inflammation in preterm birth – focus on periodontitis. Br. J. Obstet. Gynecol.113, 43–45 (2006).
   Google Scholar
• Menon R, Fortunato SJ, Thorsen P. Genetic associations in preterm birth: a primer of marker selection, study design, and data analysis. J. Soc. Gynecol. Investig.13, 531–541 (2006).
   PubMedGoogle Scholar
• Husslein P, Cabero Roura L, Dudenhausen JW. Atosiban versus usual care for the management of preterm labor. J. Perinat. Med.35, 305–313 (2007).
   PubMed Web of Science ®Google Scholar
• Smith GN, Walker MC, Ohlsson A. Randomized double-blind placebo-controlled trial of transdermal nitroglycerin for preterm labor. Am. J. Obstet. Gynecol.196(37) E1–E8 (2007).
   PubMed Web of Science ®Google Scholar
• Berghella V, Rust OA, Althuisius SM. Short cervix on ultrasound: does indomethacin prevent p,eterm birth? Am. J. Obstet. Gynecol.195, 809–813 (2006).
   PubMed Web of Science ®Google Scholar
• Grimes DA, Nanda K. Magnesium sulfate tocolysis: time to quit. Obstet. Gynecol.108, 986–989 (2006).
   PubMed Web of Science ®Google Scholar
• Thornton JG. Maintenance tocolysis. Br. J. Obstet. Gynecol.112, 118–121 (2005).
   Google Scholar
• Hollier LM. Preventing preterm birth: what works, what doesn’t. Obstet. Gynecol. Surv.60, 124–131 (2005).
   PubMed Web of Science ®Google Scholar
• Coomarasamy A, Knox EM, Gee H. Effectiveness of nifedipine versus atosiban for tocolysis in preterm labour: a meta-analysis with an indirect comparison of randomised trials. Br. J. Obstet. Gynecol.110, 1045–1049 (2003).
   Google Scholar
• King J, Flenady V, Cole S, Thornton S. Cyclo-oxygenase (COX) inhibitors for treating preterm labour. Cochrane Database Syst. Rev.2, CD001992 (2005).
   Google Scholar
• Combs CA, McCune M, Clark R, Fishman A. Aggressive tocolysis does not prolong pregnancy or reduce neonatal morbidity after preterm premature rupture of the membranes. Am. J. Obstet. Gynecol.190, 1723–1728 (2004).
   PubMed Web of Science ®Google Scholar
• Lockwood CJ. Testing for risk of preterm delivery. Clin. Lab. Med.23, 345–360 (2003).
   PubMed Web of Science ®Google Scholar
• Lockwood CJ, Kuczynski E. Markers of risk for preterm delivery. J. Perinat. Med.27, 5–20 (1999).
   PubMed Web of Science ®Google Scholar
• Lockwood CJ, Kuczynski E. Risk stratification and pathological mechanisms in preterm delivery. Paediatr. Perinat. Epidemiol.15, 78–89 (2001).
   PubMed Web of Science ®Google Scholar
• US Department of Health and Human Services. ‘Innovation or Stagnation? – Challenge and Opportunity on the Critical Path to New Medical Products. March 2004.
   Google Scholar
• Slamon DJ, Leyland-Jones B, Shak S. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N. Engl. J. Med.344, 783–792 (2001).
   PubMed Web of Science ®Google Scholar
• Cunningham D, Humblet Y, Siena S. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N. Engl. J. Med.351, 337–345 (2004).
   PubMed Web of Science ®Google Scholar
• Nesin M. Genetic basis of preterm birth. Front. Biosci.12, 115–124 (2007).
   PubMed Web of Science ®Google Scholar
• Lee SJ, Steer PJ, Filippi V. Seasonal patterns and preterm birth: a systematic review of the literature and an analysis in a London-based cohort. Br. J. Obstet. Gynecol.113, 1280–1288 (2006).
   Google Scholar
• Gilbreath S, Kass PH. Adverse birth outcomes associated with open dumpsites in Alaska Native Villages. Am. J. Epidemiol.164, 518–528 (2006).
   PubMed Web of Science ®Google Scholar
• Macones GA, Parry S, Elkousy M. A polymorphism in the promoter region of TNF and bacterial vaginosis: preliminary evidence of gene–environment interaction in the etiology of spontaneous preterm birth. Am. J. Obstet. Gynecol.190, 1504–1508 (2004).
   PubMed Web of Science ®Google Scholar
• Venter JC, Adams MD, Myers EW. The sequence of the human genome. Science291, 1304–1351 (2001).
   PubMed Web of Science ®Google Scholar
• Aguan K, Carvajal JA, Thompson LP. Application of a functional genomics approach to identify differentially expressed genes in human myometrium during pregnancy and labour. Mol. Hum. Reprod.6, 1141–1145 (2000).
   PubMed Web of Science ®Google Scholar
• Bukowski R, Hankins GD, Saade GR. Labor-associated gene expression in the human uterine fundus, lower segment, and cervix. PLoS Med.3, E169 (2006).
   PubMed Web of Science ®Google Scholar
• Havelock JC, Keller P, Muleba N. Human myometrial gene expression before and during parturition. Biol. Reprod.72, 707–719 (2005).
   PubMed Web of Science ®Google Scholar
• Buhimschi CS, Mason CW, Swaan PW. Evidence that innate immunity is activated in myometrium from women in term and preterm labor. Presented at: Society for Gynecologic Investigation. Toronto, Canada, 22–25 March 2006.
   Google Scholar
• Lieber CD. Introduction to Proteomics. Tools for the New Biology. Lieber CD (Ed.). Humana Press Inc., NJ, USA, 3–14 (2002).
   Google Scholar
• Buhimschi CS, Weiner CP, Buhimschi IA. Clinical proteomics: a novel diagnostic tool for the new biology of preterm labor, part I: proteomics tools. Obstet. Gynecol. Surv.61, 481–486 (2006).
   PubMed Web of Science ®Google Scholar
• Bahtiyar MO, Copel JA, Mahoney MJ. Proteomics: a novel methodology to complement prenatal diagnosis of chromosomal abnormalities and inherited human diseases. Am. J. Perinatol.24, 167–181 (2007).
   PubMed Web of Science ®Google Scholar
• Shankar R, Cullinane F, Brennecke SP, Moses EK. Applications of proteomic methodologies to human pregnancy research: a growing gestation approaching delivery? Proteomics4, 1909–1917 (2004).
   PubMed Web of Science ®Google Scholar
• Menon R, Fortunato SJ. Infection and the role of inflammation in preterm premature rupture of the membranes. Best Pract. Res. Clin. Obstet. Gynaecol.21, 467–478 (2007).
   PubMed Web of Science ®Google Scholar
• Bernstein S, Heimler R, Sasidharan P. Approaching the management of the neonatal intensive care unit graduate through history and physical assessment. Ped. Clin. North Am.45, 79–105 (1998).
   PubMed Web of Science ®Google Scholar
• Mercer BM. Is there a role for tocolytic therapy during conservative management of preterm premature rupture of the membranes? Clin. Obstet. Gynecol.50, 487–496 (2007).
   PubMed Web of Science ®Google Scholar
• Buhimschi IA, Kramer WB, Buhimschi CS. Reduction–oxidation (redox) state regulation of matrix metalloproteinase activity in human fetal membranes. Am. J. Obstet. Gynecol.182, 458–464 (2000).
   PubMed Web of Science ®Google Scholar
• Wilkins MR, Sanchez JC, Gooley AA. Progress with proteome projects: why all proteins expressed by a genome should be identified and how to do it. Biotechnol. Genet. Eng. Rev.13, 19–50 (1996).
   PubMed Web of Science ®Google Scholar
• Buhimschi IA, Christner R, Buhimschi CS. Proteomic biomarker analysis of amniotic fluid for identification of intra-amniotic inflammation. Br. J. Obstet. Gynecol.112, 173–181 (2005).
   Google Scholar
• Vuadens F, Benay C, Crettaz D. Identification of biologic markers of the premature rupture of fetal membranes: proteomic approach. Proteomics3, 1521–1525 (2003).
   PubMed Web of Science ®Google Scholar
• Michel PE, Crettaz D, Morier P. Proteome analysis of human plasma and amniotic fluid by Off-GelTM isoelectric focusing followed by nano-LC-MS/MS. Electrophoresis27, 1169–11681 (2006).
   PubMed Web of Science ®Google Scholar
• Buhimschi IA, Buhimschi CS, Weiner CP. Proteomic but not enzyme-linked immunosorbent assay technology detects amniotic fluid monomeric calgranulins from their complexed calprotectin form. Clin. Diagn. Lab. Immunol.12, 837–844 (2005).
   PubMedGoogle Scholar
• Gravett MG, Novy MJ, Rosenfeld RG. Diagnosis of intra-amniotic infection by proteomic profiling and identification of novel biomarkers. JAMA292, 462–469 (2005).
   Web of Science ®Google Scholar
• Ruetschi U, Rosen A, Karlsson G. Proteomic analysis using protein chips to detect biomarkers in cervical and amniotic fluid in women with intra-amniotic inflammation. J. Proteome Res.4, 2236–2242 (2005).
   PubMed Web of Science ®Google Scholar
• Biron DG, Brun C, Lefevre T. The pitfalls of proteomics experiments without the correct use of bioinformatics tools. Proteomics6, 5577–5596 (2006).
   PubMed Web of Science ®Google Scholar
• Hermjakob H, Apweiler R. The Proteomics Identifications Database (PRIDE) and the ProteomExchange Consortium: making proteomics data accessible. Expert Rev. Proteomics3, 1–3 (2006).
   PubMed Web of Science ®Google Scholar
• Lo SL, You T, Lin Q. SPLASH: Systematic Proteomics Laboratory Analysis and Storage Hub. Proteomics6, 1758–1769 (2006).
   PubMed Web of Science ®Google Scholar
• Morita A, Miyagi E, Yasumitsu H. Proteomic search for potential diagnostic markers and therapeutic targets for ovarian clear cell adenocarcinoma. Proteomics6, 5880–5890 (2006).
   PubMed Web of Science ®Google Scholar
• Zhang H, Kong B, Qu X, Jia L. Biomarker discovery for ovarian cancer using SELDI-TOF-MS. Gynecol. Oncol.102, 61–66 (2006).
   PubMed Web of Science ®Google Scholar
• Taguchi F, Solomon B, Gregorc V. Mass spectrometry to classify non-small-cell lung cancer patients for clinical outcome after treatment with epidermal growth factor receptor tyrosine kinase inhibitors: a multicohort cross-institutional study. J. Natl Cancer Inst.99, 838–846 (2007).
   PubMed Web of Science ®Google Scholar
• Hellstrom M, Lexander H, Franzen B. Proteomics in prostate cancer research. Anal. Quant. Cytol. Histol.29, 32–40 (2007).
   PubMed Web of Science ®Google Scholar
• Lopez MF, Mikulskis A, Kuzdzal S. High-resolution serum proteomic profiling of Alzheimer disease samples reveals disease-specific, carrier-protein-bound mass signatures. Clin. Chem.51, 1946–1954 (2005).
   PubMed Web of Science ®Google Scholar
• Ransohoff DF. Lessons from controversy: ovarian cancer screening and serum proteomics. J. Natl Cancer Inst.97, 315–319 (2005).
   PubMed Web of Science ®Google Scholar
• Anderson NL, Anderson NG. The human plasma proteome: history, character, and diagnostic prospects. Mol. Cell. Proteomics1, 845–867 (2002).
   PubMed Web of Science ®Google Scholar
• Sampson JE, Theve RP, Blatman RN. Fetal origin of amniotic fluid polymorphonuclear leukocytes. Am. J. Obstet. Gynecol.176, 77–81 (1997).
   PubMed Web of Science ®Google Scholar
• Buhimschi CS, Pettker CM, Magloire LK. Proteomic technology and delayed interval delivery in multiple pregnancies. Int. J. Gynaecol. Obstet.90, 48–50 (2005).
   PubMed Web of Science ®Google Scholar
• Cho CKJ, Shan SJ, Winsor EJ, Diamandis EP. Proteomic analysis of human amniotic fluid. Mol. Cell. Proteomics6, 1406–1415 (2007).
   PubMed Web of Science ®Google Scholar
• Michaels JE, Dasari S, Pereira L. Comprehensive proteomic analysis of the human amniotic fluid proteome: gestational age-dependent changes. J. Proteome Res.6, 1277–1285 (2007).
   PubMed Web of Science ®Google Scholar
• Buhimschi CS, Bhandari V, Hamar BD. Proteomic profiling of the amniotic fluid to detect inflammation, infection, and neonatal sepsis. PLoS Med.4(1), e18 (2007).
   PubMed Web of Science ®Google Scholar
• Buhimschi CS, Buhimschi IA, Abdel-Razeq S. Proteomic biomarkers of intra-amniotic inflammation: relationship with funisitis and early-onset sepsis in the premature neonate. Pediatr. Res.61, 318–324 (2007).
   PubMed Web of Science ®Google Scholar
• Hofmann MA, Drury S, Fu C. RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides. Cell97, 889–901 (1999).
   PubMed Web of Science ®Google Scholar
• Buhimschi IA, Zhao G, Pettker CM. The receptor for advanced glycation end products (RAGE) system in women with intraamniotic infection and inflammation. Am. J. Obstet. Gynecol.196(181), E1–E13 (2007).
   PubMed Web of Science ®Google Scholar
• Lockwood CJ. Pregnancy-associated changes in the hemostatic system. Clin. Obstet. Gynecol.49, 836–843 (2006).
   PubMed Web of Science ®Google Scholar
• Salafia CM, Lopez-Zeno JA, Sherer DM. Histologic evidence of old intrauterine bleeding is more frequent in prematurity. Am. J. Obstet. Gynecol.173, 1065–1070 (1995).
   PubMed Web of Science ®Google Scholar
• Lockwood CJ, Krikun G, Rahman M. The role of decidualization in regulating endometrial hemostasis during the menstrual cycle, gestation, and in pathological states. Semin. Thromb. Hemost.33, 111–117 (2007).
   PubMed Web of Science ®Google Scholar
• Weiner CP, Lee KY, Buhimschi CS. Proteomic biomarkers that predict the clinical success of rescue cerclage. Am. J. Obstet. Gynecol.192, 710–718 (2005).
   PubMed Web of Science ®Google Scholar
• Lockwood CJ, Toti P, Arcuri F. Mechanisms of abruption-induced premature rupture of the fetal membranes: thrombin-enhanced interleukin-8 expression in term decidua. Am. J. Pathol.167, 1443–1449 (2005).
   PubMed Web of Science ®Google Scholar
• Buhimschi IA, Christner R, Buhimschi CS. Proteomic biomarker analysis of amniotic fluid for identification of intra-amniotic inflammation. Br. J. Obstet. Gynecol.112, 173–181 (2005).
   Google Scholar
• Buhimschi CS, Sfakianaki AK, Hamar BG. A low vaginal ‘pool’ amniotic fluid glucose measurement is a predictive but not a sensitive marker for infection in women with preterm premature rupture of membranes. Am. J. Obstet. Gynecol.194, 309–316 (2006).
   PubMed Web of Science ®Google Scholar
• Lewis DF, Robichaux AG, Jaekle RK. Expectant management of preterm premature rupture of membranes and nonvertex presentation: what are the risks? Am. J. Obstet. Gynecol.196(566), E1–E5 (2007).
   PubMed Web of Science ®Google Scholar
• Mercer BM. Is there a role for tocolytic therapy during conservative management of preterm premature rupture of the membranes? Clin. Obstet. Gynecol.50, 487–496 (2007).
   PubMed Web of Science ®Google Scholar
• ACOG Committee on Practice Bulletins–Obstetrics. ACOG Practice Bulletin No. 80: premature rupture of membranes. Clinical management guidelines for obstetrician–gynecologists. Obstet. Gynecol.109, 1007–1019 (2007).
   PubMedGoogle Scholar
• Menon R, Fortunato SJ. The role of matrix degrading enzymes and apoptosis in rupture of membranes. J. Soc. Gynecol. Investig.11, 427–437 (2004).
   PubMedGoogle Scholar
• Thadikkaran L, Crettaz D, Siegenthaler MA. The role of proteomics in the assessment of premature rupture of fetal membranes. Clin. Chim. Acta360, 27–36 (2005).
   PubMed Web of Science ®Google Scholar
• Buhimschi IA, Buhimschi CS, Norwitz E. Proteomic analysis of cervico–vaginal secretions during pregnancy. Presented at: The Society for Maternal–Fetal Medicine, Reno, NV, USA, 7–12 February 2005.
   Google Scholar
• Di Quinzio MK, Oliva K, Holdsworth SJ. Proteomic analysis and characterisation of human cervico–vaginal fluid proteins. Clin. Aust. NZ J. Obstet. Gynaecol.47, 9–15 (2007).
   PubMed Web of Science ®Google Scholar
• Pereira L, Reddy AP, Jacob T. Identification of novel protein biomarkers of preterm birth in human cervical–vaginal fluid. J. Proteome Res.6, 1269–1276 (2007).
   PubMed Web of Science ®Google Scholar
• Buhimschi IA, Buhimschi CS, Weiner CP. Proteomic but not enzyme-linked immunosorbent assay technology detects amniotic fluid monomeric calgranulins from their complexed calprotectin form. Clin. Diagn. Lab. Immunol.12, 837–844 (2005).
   PubMedGoogle Scholar
• Kunimi K, Maegawa M, Kamada M. Myeloid-related protein-8/14 is associated with proinflammatory cytokines in cervical mucus. J. Reprod. Immunol.71, 3–11 (2006).
   PubMed Web of Science ®Google Scholar