An overview of platelet function in normal and complicated pregnancies

References

• McCrae KR. Thrombocytopenia in pregnancy: differential diagnosis, pathogenesis, and management. Blood Reviews 17(4), 265 (2003).
   Web of Science ®Google Scholar
• Valera MC, Parant O, Vayssiere C, Arnal JF, Payrastre B. Physiologic and pathologic changes of platelets in pregnancy. Platelets 21(8), 587–595 (2010).
   PubMed Web of Science ®Google Scholar
• Askie LM, Duley L, Henderson-Smart DJ, Stewart LA; PARIS Collaborative Group. Antiplatelet agents for prevention of pre-eclampsia: a meta-analysis of individual patient data. Lancet 369(9575), 1791–1798 (2007).
   PubMed Web of Science ®Google Scholar
• Fuster V, Badimon L, Badimon JJ, Chesebro JH. The pathogenesis of coronary artery disease and the acute coronary syndromes (2). N. Engl. J. Med. 326(5), 310–318 (1992).
   PubMed Web of Science ®Google Scholar
• Peace AJ, Tedesco AF, Foley DP, Dicker P, Berndt MC, Kenny D. Dual antiplatelet therapy unmasks distinct platelet reactivity in patients with coronary artery disease. J. Thromb. Haemost. 6(12), 2027–2034 (2008).
   PubMed Web of Science ®Google Scholar
• Gachet C. Identification, characterization, and inhibition of the platelet ADP receptors. Int. J. Hematol. 74(4), 375–381 (2001).
   PubMed Web of Science ®Google Scholar
• Jackson SP, Nesbitt WS, Kulkarni S. Signaling events underlying thrombus formation. J. Thromb. Haemost. 1(7), 1602–1612 (2003).
   PubMed Web of Science ®Google Scholar
• Jackson SP. The growing complexity of platelet aggregation. Blood 109(12), 5087–5095 (2007).
   PubMed Web of Science ®Google Scholar
• Maxwell MJ, Westein E, Nesbitt WS, Giuliano S, Dopheide SM, Jackson SP. Identification of a 2-stage platelet aggregation process mediating shear-dependent thrombus formation. Blood 109(2), 566–576 (2007).
   PubMed Web of Science ®Google Scholar
• Harrison P, Mackie I, Mumford A et al.; British Committee for Standards in Haematology. Guidelines for the laboratory investigation of heritable disorders of platelet function. Br. J. Haematol. 155(1), 30–44 (2011).
   PubMed Web of Science ®Google Scholar
• Hung J, Lam JY, Lacoste L, Letchacovski G. Cigarette smoking acutely increases platelet thrombus formation in patients with coronary artery disease taking aspirin. Circulation 92(9), 2432–2436 (1995).
   PubMed Web of Science ®Google Scholar
• Wang JS, Jen CJ, Kung HC, Lin LJ, Hsiue TR, Chen HI. Different effects of strenuous exercise and moderate exercise on platelet function in men. Circulation 90(6), 2877–2885 (1994).
   PubMed Web of Science ®Google Scholar
• Dalby MC, Davidson SJ, Burman JF, Davies SW. Diurnal variation in platelet aggregation iwth the PFA-100 platelet function analyser. Platelets 11(6), 320–324 (2000).
   PubMed Web of Science ®Google Scholar
• Feuring M, Wehling M, Ruf A, Schultz A. Circadian variation of platelet function measured with the PFA-100. Platelets 20(7), 466–470 (2009).
   PubMed Web of Science ®Google Scholar
• Pierre S, Crosbie L, Duttaroy AK. Inhibitory effect of aqueous extracts of some herbs on human platelet aggregation in vitro. Platelets 16(8), 469–473 (2005).
   PubMed Web of Science ®Google Scholar
• Feuring M, Christ M, Roell A et al. Alterations in platelet function during the ovarian cycle. Blood Coagul. Fibrinolysis 13(5), 443–447 (2002).
   PubMed Web of Science ®Google Scholar
• Refaai MA, Frenkel E, Sarode R. Platelet aggregation responses vary over a period of time in healthy controls. Platelets 21(6), 460–463 (2010).
   PubMed Web of Science ®Google Scholar
• Peace AJ, Egan K, Kavanagh GF et al. Reducing intra-individual variation in platelet aggregation: implications for platelet function testing. J. Thromb. Haemost. 7(11), 1941–1943 (2009).
   PubMed Web of Science ®Google Scholar
• Mylotte D, Foley D, Kenny D. Platelet function testing: methods of assessment and clinical utility. Cardiovasc. Hematol. Agents Med. Chem. 9(1), 14–24 (2011).
   PubMedGoogle Scholar
• Breet NJ, van Werkum JW, Bouman HJ, Kelder JC, Ten Berg JM, Hackeng CM. High on-aspirin platelet reactivity as measured with aggregation-based, cyclooxygenase-1 inhibition sensitive platelet function tests is associated with the occurrence of atherothrombotic events. J. Thromb. Haemost. 8(10), 2140–2148 (2010).
   PubMed Web of Science ®Google Scholar
• Gum PA, Kottke-Marchant K, Welsh PA, White J, Topol EJ. A prospective, blinded determination of the natural history of aspirin resistance among stable patients with cardiovascular disease. J. Am. Coll. Cardiol. 41(6), 961–965 (2003).
   PubMed Web of Science ®Google Scholar
• McGlasson DL, Fritsma GA. Whole blood platelet aggregometry and platelet function testing. Semin. Thromb. Hemost. 35(2), 168–180 (2009).
   PubMed Web of Science ®Google Scholar
• Holmes VA, Wallace JM, Gilmore WS, McFaul P, Alexander HD. Soluble P-selectin levels during normal pregnancy: a longitudinal study. BJOG 109(9), 997–1002 (2002).
   PubMed Web of Science ®Google Scholar
• Lok CA, Nieuwland R, Sturk A et al. Microparticle-associated P-selectin reflects platelet activation in preeclampsia. Platelets 18(1), 68–72 (2007).
   PubMed Web of Science ®Google Scholar
• Davenport R. Pathogenesis of acute traumatic coagulopathy. Transfusion 53(Suppl. 1), 23S–27S (2013).
   PubMed Web of Science ®Google Scholar
• Macafee B, Campbell JP, Ashpole K et al. Reference ranges for thromboelastography (TEG(®)) and traditional coagulation tests in term parturients undergoing caesarean section under spinal anaesthesia*. Anaesthesia 67(7), 741–747 (2012).
   PubMed Web of Science ®Google Scholar
• Italiano JE Jr, Mairuhu AT, Flaumenhaft R. Clinical relevance of microparticles from platelets and megakaryocytes. Curr. Opin. Hematol. 17(6), 578–584 (2010).
   PubMed Web of Science ®Google Scholar
• Alijotas-Reig J, Palacio-Garcia C, Llurba E, Vilardell-Tarres M. Cell-derived microparticles and vascular pregnancy complications: a systematic and comprehensive review. Fertil. Steril. 99(2), 441–449 (2013).
   PubMed Web of Science ®Google Scholar
• Norris LA, Gleeson N, Sheppard BL, Bonnar J. Whole blood platelet aggregation in moderate and severe pre-eclampsia. Br. J. Obstet. Gynaecol. 100(7), 684–688 (1993).
   PubMedGoogle Scholar
• Roell A, Schueller P, Schultz A et al. Effect of oral contraceptives and ovarian cycle on platelet function. Platelets 18(2), 165–170 (2007).
   PubMed Web of Science ®Google Scholar
• Toth B, Nikolajek K, Rank A et al. Gender-specific and menstrual cycle dependent differences in circulating microparticles. Platelets 18(7), 515–521 (2007).
   PubMed Web of Science ®Google Scholar
• Stirling Y, Woolf L, North WR, Seghatchian MJ, Meade TW. Haemostasis in normal pregnancy. Thromb. Haemost. 52(2), 176–182 (1984).
   PubMed Web of Science ®Google Scholar
• McColl MD, Ramsay JE, Tait RC et al. Risk factors for pregnancy associated venous thromboembolism. Thromb. Haemost. 78(4), 1183–1188 (1997).
   PubMed Web of Science ®Google Scholar
• Clark P. Changes of hemostasis variables during pregnancy. Semin. Vasc. Med. 3(1), 13–24 (2003).
   PubMedGoogle Scholar
• Condie RG. A serial study of coagulation factors XII, XI and X in plasma in normal pregnancy and in pregnancy complicated by pre-eclampsia. Br. J. Obstet. Gynaecol. 83(8), 636–639 (1976).
   PubMedGoogle Scholar
• Lindoff C, Astedt B. Fibrinolytic components in individual consecutive plasma samples during normal pregnancy. Fibrinolysis. 7(3), 190–194 (1993).
   Google Scholar
• Greer IA. Haemostasis and Thrombosis in Pregnancy. Bloom AL, Thomas DP, Tuddenham EGD (Eds). Churchill Livingstone, Edinburgh, UK (1994).
   Google Scholar
• Douglas JT, Shah M, Lowe GD, Belch JJ, Forbes CD, Prentice CR. Plasma fibrinopeptide A and beta-thromboglobulin in pre-eclampsia and pregnancy hypertension. Thromb. Haemost. 47(1), 54–55 (1982).
   PubMed Web of Science ®Google Scholar
• Harlow FH, Brown MA, Brighton TA et al. Platelet activation in the hypertensive disorders of pregnancy. Am. J. Obstet. Gynecol. 187(3), 688–695 (2002).
   PubMed Web of Science ®Google Scholar
• Holthe MR, Staff AC, Berge LN, Lyberg T. Different levels of platelet activation in preeclamptic, normotensive pregnant, and nonpregnant women. Am. J. Obstet. Gynecol. 190(4), 1128–1134 (2004).
   PubMed Web of Science ®Google Scholar
• Morrison R, Crawford J, MacPherson M, Heptinstall S. Platelet behaviour in normal pregnancy, pregnancy complicated by essential hypertension and pregnancy-induced hypertension. Thromb. Haemost. 54(3), 607–611 (1985).
   PubMed Web of Science ®Google Scholar
• Salamalekis E, Stamou E, Loghis C, Papageorgiou E, Papoulias I, Panayotopoulos N. Platelet reactivity is increased in mild gestational diabetes compared with normal pregnancy. J. Obstet. Gynaecol. 17(3), 255–257 (1997).
   PubMedGoogle Scholar
• Erez O, Romero R, Hoppensteadt D et al. Premature labor: a state of platelet activation? J. Perinat. Med. 36(5), 377–387 (2008).
   PubMed Web of Science ®Google Scholar
• Gatti L, Tenconi PM, Guarneri D et al. Hemostatic parameters and platelet activation by flow-cytometry in normal pregnancy: a longitudinal study. Int. J. Clin. Lab. Res. 24(4), 217–219 (1994).
   PubMedGoogle Scholar
• Star J, Rosene K, Ferland J, DiLeone G, Hogan J, Kestin A. Flow cytometric analysis of platelet activation throughout normal gestation. Obstet. Gynecol. 90(4 Pt 1), 562–568 (1997).
   PubMed Web of Science ®Google Scholar
• Janes SL, Goodall AH. Flow cytometric detection of circulating activated platelets and platelet hyper-responsiveness in pre-eclampsia and pregnancy. Clin. Sci. 86(6), 731–739 (1994).
   PubMed Web of Science ®Google Scholar
• Louden KA, Broughton Pipkin F, Heptinstall S, Fox SC, Mitchell JR, Symonds EM. A longitudinal study of platelet behaviour and thromboxane production in whole blood in normal pregnancy and the puerperium. Br. J. Obstet. Gynaecol. 97(12), 1108–1114 (1990).
   PubMedGoogle Scholar
• Sheu JR, Hsiao G, Shen MY, Lin WY, Tzeng CR. The hyperaggregability of platelets from normal pregnancy is mediated through thromboxane A2 and cyclic AMP pathways. Clin. Lab. Haematol. 24(2), 121–129 (2002).
   PubMedGoogle Scholar
• Sato Y, Fujiwara H, Konishi I. Role of platelets in placentation. Med. Mol. Morphol. 43(3), 129–133 (2010).
   PubMed Web of Science ®Google Scholar
• Sato Y, Fujiwara H, Zeng BX, Higuchi T, Yoshioka S, Fujii S. Platelet-derived soluble factors induce human extravillous trophoblast migration and differentiation: platelets are a possible regulator of trophoblast infiltration into maternal spiral arteries. Blood 106(2), 428–435 (2005).
   PubMed Web of Science ®Google Scholar
• Can MM, Kaymaz C, Can E et al. Whole blood platelet aggregation failed to detect differences between preeclampsia and normal pregnancy. Platelets 21(6), 496–497 (2010).
   PubMed Web of Science ®Google Scholar
• Peraçoli MT, Menegon FT, Borges VT, de Araújo Costa RA, Thomazini-Santos IA, Peraçoli JC. Platelet aggregation and TGF-beta(1) plasma levels in pregnant women with preeclampsia. J. Reprod. Immunol. 79(1), 79–84 (2008).
   PubMed Web of Science ®Google Scholar
• O’Brien WF, Saba HI, Knuppel RA, Scerbo JC, Cohen GR. Alterations in platelet concentration and aggregation in normal pregnancy and preeclampsia. Am. J. Obstet. Gynecol. 155(3), 486–490 (1986).
   PubMed Web of Science ®Google Scholar
• Oron G, Ben-Haroush A, Hod M, Orvieto R, Bar J. Serum-soluble CD40 ligand in normal pregnancy and in preeclampsia. Obstet. Gynecol. 107(4), 896–900 (2006).
   PubMed Web of Science ®Google Scholar
• Konijnenberg A, van der Post JA, Mol BW et al. Can flow cytometric detection of platelet activation early in pregnancy predict the occurrence of preeclampsia? A prospective study. Am. J. Obstet. Gynecol. 177(2), 434–442 (1997).
   PubMed Web of Science ®Google Scholar
• Bujold E, Roberge S, Lacasse Y et al. Prevention of preeclampsia and intrauterine growth restriction with aspirin started in early pregnancy: a meta-analysis. Obstet. Gynecol. 116(2 Pt 1), 402–414 (2010).
   PubMed Web of Science ®Google Scholar
• Brouillet S, Murthi P, Hoffmann P et al. EG-VEGF controls placental growth and survival in normal and pathological pregnancies: case of fetal growth restriction (FGR). Cell. Mol. Life Sci. 70(3), 511–525 (2013).
   PubMed Web of Science ®Google Scholar
• Wallenburg HC, Rotmans N. Enhanced reactivity of the platelet thromboxane pathway in normotensive and hypertensive pregnancies with insufficient fetal growth. Am. J. Obstet. Gynecol. 144(5), 523–528 (1982).
   PubMed Web of Science ®Google Scholar
• Norris LA, Sheppard BL, Burke G, Bonnar J. Platelet activation in normotensive and hypertensive pregnancies complicated by intrauterine growth retardation. Br. J. Obstet. Gynaecol. 101(3), 209–214 (1994).
   PubMedGoogle Scholar
• Ahmed Y, Sullivan MH, Pearce JM, Elder MG. Changes in platelet function in pregnancies complicated by fetal growth retardation. Eur. J. Obstet. Gynecol. Reprod. Biol. 42(3), 171–175 (1991).
   PubMed Web of Science ®Google Scholar
• Missfelder-Lobos H, Teran E, Lees C, Albaiges G, Nicolaides KH. Platelet changes and subsequent development of pre-eclampsia and fetal growth restriction in women with abnormal uterine artery Doppler screening. Ultrasound Obstet. Gynecol. 19(5), 443–448 (2002).
   PubMed Web of Science ®Google Scholar
• Rai R, Tuddenham E, Backos M et al. Thromboelastography, whole-blood haemostasis and recurrent miscarriage. Hum. Reprod. 18(12), 2540–2543 (2003).
   PubMed Web of Science ®Google Scholar
• Beyan C, Kaptan K, Ifran A. Platelet aggregation abnormalities in patients with recurrent fetal losses. Thromb. Res. 121(3), 327–331 (2007).
   PubMed Web of Science ®Google Scholar
• Flood K, Peace A, Kent E et al. Platelet reactivity and pregnancy loss. Am. J. Obstet. Gynecol. 203(3), 281.e1–281.e5 (2010).
   Google Scholar
• Breet NJ, van Werkum JW, Bouman HJ et al. Comparison of platelet function tests in predicting clinical outcome in patients undergoing coronary stent implantation. JAMA 303(8), 754–762 (2010).
   PubMed Web of Science ®Google Scholar