4
Views
3
CrossRef citations to date
0
Altmetric
Review

The vanishing twin: prevalence and consequences for outcome after assisted reproduction

Pages 369-377 | Published online: 10 Jan 2014

References

  • Stoeckel W. Lehbuch der Geburtschilfe. Gustav Fischer, Jena, Germany (1945).
  • Finberg HJ, Birnholz JC. Ultrasound observations in multiple gestation with first trimester bleeding: the blighted twin. Radiology132, 137–142 (1979).
  • Landy HJ, Keith LG. The vanishing twin: a review. Hum. Reprod.4, 177–183 (1998).
  • Tharapel AT, Elias S, Shulman LP et al. Resorbed co-twin as an explanation for discrepant chorionic villus results: NonHmosaic 47,XX, +16 in villi (direct and culture) with normal (46,XX) amniotic fluid and neonatal blood. Prenat. Diagn.9, 467–472 (1989).
  • Landy HJ, Weiner S, Corson SL et al. The ‘vanishing twin’: ultrasonographic assessment of fetal disappearance in the first trimester. Am. J. Obstet. Gynecol.155, 14–19 (1986).
  • Hvidtjørn D, Grove J, Schendel D et al. ‘Vanishing embryo syndrome’ in IVF/ICSI. Hum. Reprod.20, 2550–2551 (2005).
  • Hofmann G, Gundrun C, Drake L, Bertsche A. Frequency and effect of vaginal bleeding on pregnancyoutcome during the first 3 weeks after positive B-hCG test results following IVF-ET. Fertil. Steril.74, 609–610 (2000).
  • Pezeshki K, Feldman J, Stein DE, Lobel SM, Grazi RV. Bleeding and spontaneous abortion after therapy for infertility. Fertil. Steril.74, 504–508 (2000).
  • Williams MA, Mittendorf R, Lieberman E, Monson RR. Adverse infant outcomes associated with first-trimester vaginal bleeding. Obstet. Gynecol.78, 14–18 (1991).
  • Weiss JL, Malone FD, Vidaver J et al. Threatened miscarriage: a risk for poor pregnancy outcome, a population based screening study. Am. J. Obstet. Gynecol.190, 745–750 (2004).
  • De sutter P, Bontinck J, Schutysers V, Van der Elst J, Gerris J, Dhont M. First-trimester bleeding and pregnancy outcome in singletons after assisted reproduction. Hum. Reprod.21, 1907–1911 (2006).
  • Dickey RP, Taylor SN, Lu PY et al. Spontaneous reduction of multiple pregnancy: incidence and effect on outcome. Am. J. Obstet. Gynecol.186, 77–83 (2002).
  • Tummers P, De Sutter P, Dhont M. Risk of spontaneous abortion in singleton and twin pregnancies after IVF/ICSI. Hum. Reprod.18, 1720–1723 (2003).
  • La Sala GB, Nucera G, Gallinelli A, Nicoli A, Villani MT, Blickstein I. Spontaneous embryonic loss following in vitro fertilization: incidence and effect on outcomes. Am. J. Obstet. Gynecol.191, 741–746 (2004).
  • Pinborg A, Lidegaard O, la Cour Freiesleben N, Nyboe Andersen A. consequences of vanishing twins in IVF/ICSI pregnancies. Hum. Reprod.20, 2821–2829 (2005).
  • Dickey RP, Sartor BM, Pyrzak R. What is the most relevant standard of success in assisted reproduction? No single outcome measure is satisfactory when evaluating success in assisted reproduction; both twin and singletons births should be counted as successes. Hum. Reprod.19, 783–787 (2004).
  • Schieve LA, Meikle SF, Ferre C, Peterson HB, Jeng G, Wilcox LS. Low and very low birth weight in infants conceived with use of assisted reproductive technology. N. Engl. J. Med.346, 731–737 (2002).
  • Lancaster PAL. Number of gestational sacs and singleton IVF preterm birth. Hum. Reprod.19(Suppl. 1) O245–O285 (2004).
  • La Sala GB, Nucera G, Gallinelli A, Nicoli A, Villani MT, Blickstein I. Spontaneous embryonic loss after in vitro fertilization with and without intracytoplasmic sperm injection. Fertil. Steril.82, 1536–9136 (2004).
  • Pinborg A, Lidegaard O, Freiesleben NC, Andersen AN. Vanishing twins: a predictor of small-for-gestational age in IVF singletons. Hum. Reprod.22, 2707–2714 (2007).
  • Andersen AN, Goossens V, Gianaroli L, Felberbaum R, de Mouzon J, Nygren KG. Assisted reproductive technology in Europe 2003. Results generated from European registers by ESHRE. Hum. Reprod.22, 1513–1525 (2007).
  • Stone J, Belogolovkin V, Matho A, Berkowitz RL, Moshier E, Eddleman K. Evolving trends in 2000 cases of multifetal pregnancy reduction: a single-center experience. Am. J. Obstet. Gynecol.197, 394.e1–394.e4 (2007).
  • Dodd J. Multifetal pregnancy reduction of triplet and higher-order multiple pregnancies to twins. Fertil. Steril.81, 1420–1422 (2004).
  • Belogolovkin V, Ferrara L, Moshier E, Gandhi M, Eddleman K, Stone J. Differences in fetal growth, discordancy, and placental pathology in reduced versus nonreduced twins. Am. J. Perinatol.24, 575–580 (2007).
  • Depp R, Macones GA, Rosenn MF, Turzo E, Wapner RJ, Weinblatt VJ. Multifetal pregnancy reduction: evaluation of fetal growth in the remaining twin. Am. J. Obstet. Gynecol.174, 1233–1240 (1996).
  • Audibert F, Boullier M, Boithias C, Kerbrat V, Vial M, Frydman R. Embryo reduction and birth weight discordance in dichorionic twins. Hum. Reprod.18, 437–440 (2003).
  • Papageorghiou AT, Vigdou K, Bakoulas V, Sebire NJ, Nicolaides KH. Risk of miscarriage and early preterm birth in trichorionic triplet pregnancies with embryo reduction versus expectant management: new data and systematic review. Hum. Reprod.21, 1912–1917 (2006).
  • Petterson B, Nelson KB, Watson L, Stanley F. Twins, triplets, and cerebral palsy in births in Western Australia in the 1980’s. Br. Med. J.307, 1239–1243 (1993).
  • Pharoah POD, Adi Y. Consequences of in-utero death in a twin pregnancy. Lancet355, 1597–1602 (2000).
  • Scher AI, Petterson B, Blair E et al. The risk of mortality or cerebral palsy in twins: a collaborative population-based study. Pediatr. Res.52, 671–681 (2002).
  • Helmerhorst FM, Perquin DAM, Donker D, Keirse MJNC. Perinatal outcome of singletons and twins after assisted conception: a systematic review of controlled studies. Br. Med. J.328, 261–265 (2004).
  • Jackson RA, Gibson KA, Wu YW, Croughan MS. Perinatal outcomes in singletons following in vitro fertilization: a meta-analysis. Obstet. Gynecol.103, 551–563 (2004).
  • Schieve LA, Ferre C, Peterson HB et al. Perinatal outcome among singleton infants conceived through asssisted reproductive technology in the united states. Obstet. Gynecol.103, 1144–1153 (2004).
  • Hansen M, Bower C, Milne E, de Klerk N, Kurinczuk JJ. Assisted reproductive technologies and the risk of birth defects – a systematic review. Hum. Reprod.20, 328–338 (2005).
  • Källén B, Finnström O, Nygren KG, Olausson PO. in vitro fertilization (IVF) in Sweden: risk for congenital malformations after different IVF methods. Birth Defects Res. (Part A)73, 162–169 (2005).
  • Strömberg B, Dahlquist G, Ericson A, Finnström O, Köster M, Stjernquist K. Neurological sequelae in children born after in-vitro fertilisation: a population based study. Lancet359, 461–465 (2002).
  • Källén B, Finnström O, Nygren K-G, Olausson PO. in vitro fertilization in Sweden: child morbidity including cancer risk. Fertil. Steril.84, 605–610 (2005).
  • Lidegaard Ø, Pinborg A, Nyboe Andersen A. Imprinting diseases and IVF. Danish National IVF cohort study. Hum. Reprod.20, 950–954 (2005).
  • De Sutter P, Veldeman L, Kok P, Szymczak N, Van der Elst J, Dhont M. Comparison of outcome of pregnancy after intra-uterine insemination (IUI) and IVF. Hum. Reprod.20, 1642–1646 (2005).
  • Ombelet W, Martens G, De Sutter P et al. Perinatal outcome of 12,021 singleton and 3108 twin births after non-IVF-assisted reproduction: a cohort study. Hum. Reprod.21, 1025–1032 (2006).
  • Griesinger G, Diedrich K, Ludwig M. Parameters of ovarian stimulation are not associated with the birth weight after IVF in women aged 25–35 years: an analysis of 32.000 singletons. Hum. Reprod.22(Suppl. 1) 103 (2007).
  • Baart EB, Martini E, Eijkemans MJ et al. Milder ovarian stimulation for in-vitro fertilization reduces aneuploidy in the human preimplantation embryo: a randomized controlled trial. Hum. Reprod.22, 980–988 (2007).
  • Henriksen TB, Baird DD, Olsen J, Hedegaard M, Secher NJ, Wilcox AJ. Time to pregnancy and preterm delivery. Obstet. Gynecol.89, 594–599 (1997).
  • Draper ES, Kurinczuk JJ, Abrams KR, Clarke M. Assessment of separate contributions to perinatal mortality of infertility history and treatment: a case-control analysis. Lancet353, 1746–1749 (1999).
  • Pandian Z, Bhattacharya S, Templeton A. Review of unexplained infertility and obstetric outcome: a 10 year review. Hum. Reprod.16, 2593–2597 (2001).
  • Basso O, Baird DD. Infertility and preterm delivery, birthweight, and caesarean section: a study within the Danish National Birth Cohort. Hum. Reprod.18, 2478–2484 (2003).
  • Basso O, Olsen J. Subfecundity and neonatal mortality: longitudinal study within the Danish National Birth Cohort. Br. Med. J.330, 393–394 (2005).
  • Zhu JL, Basso O, Obel C, Bille C, Olsen J. Infertility, infertility treatment, and congenital malformations: Danish national birth cohort. Br. Med. J.333, 679 (2006).
  • De Neubourg D, Gerris J, Mangelschots K et al. The obstetrical and neonatal outcome of babies born after single-embryo transfer in IVF/ICSI compares favourably to spontaneously conceived babies. Hum. Reprod.21, 1041–1046 (2006).
  • De Sutter P, Delbaere I, Gerris J et al. Birthweight of singletons after assisted reproduction is higher after single- than after double-embryo transfer. Hum. Reprod.21, 2633–2637 (2006).
  • Kjellberg AT, Carlsson P, Bergh C. Randomized single versus double embryo transfer: obstetric and paediatric outcome and a cost–effectiveness analysis. Hum. Reprod.21, 210–216 (2006).
  • Poikkeus P, Gissler M, Unkila-Kallio L, Hyden-Granskog C, Tiitinen A. Obstetric and neonatal outcome after single embryo transfer. Hum. Reprod.22, 1073–1079 (2007).
  • Thurin A, Hausken J, Hillensjö T et al. Elective single-embryo transfer versus double-embryo transfer in in vitro fertilization. N. Engl. J. Med.351(23), 2392–2402 (2004).

Websites

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.