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Review

Helicobacter pylori: host genetics and disease outcomes

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Pages 577-585 | Published online: 10 Jan 2014

References

  • Marshall BJ, Warren JR. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet1, 1311–1315 (1984).
  • IARC monographs on the evaluation of carcinogenic risks to humans, Vol. 61. Schistosomes, liver flukes and Helicobacter pylori. IARC, Lyon, France, 177–240 (1994).
  • Malaty HM, El-Kasabany A, Graham DY et al. Age at acquisition of Helicobacter pylori infection: a follow-up study from infancy to adulthood. Lancet359, 931–935 (2002).
  • Parsonnet J, Shmuely H, Haggerty T. Fecal and oral shedding of Helicobacter pylori from healthy infected adults. JAMA282, 2240–2245 (1999).
  • Taylor DN, Blaser MJ. The epidemiology of Helicobacter pylori infection. Epidemiol. Rev.13, 42–59 (1991).
  • Freeman HJ. Disappearance of Helicobacter without antibiotics in 12 patients with gastritis. Can. J. Gastroenterol.11, 167–172 (1997).
  • Tham TC, Sloan JM, Collins JS. Long-term semi-quantitative follow-up of Helicobacter pylori associated gastritis. Ir. J. Med. Sci.166, 132–134 (1997).
  • Amieva MR, El-Omar EM. Host-bacterial interactions in Helicobacter pylori infection. Gastroenterology134, 306–323 (2008).
  • Graham DY, Opekun AR, Osato MS et al. Challenge model for Helicobacter pylori infection in human volunteers. Gut53, 1235–1243 (2004).
  • Danon SJ, O’Rourke JL, Moss ND et al. The importance of local acid production in the distribution of Helicobacter felis in the mouse stomach. Gastroenterology108, 1386–1395 (1995).
  • Kuipers EJ, Lundell L, Klinkenberg-Knol EC et al. Atrophic gastritis and Helicobacter pylori infection in patients with reflux esophagitis treated with omeprazole or fundoplication. N. Engl. J. Med.33, 1018–1022 (1996).
  • Israel DA, Peek RM. Pathogenesis of Helicobacter pylori-induced gastric inflammation. Aliment Pharmacol. Ther.15, 1271–1290 (2001).
  • Robert A, Olafsson AS, Lancaster C et al. Interleukin-1 is cytoprotective, antisecretory, stimulates PGE2 synthesis by the stomach, and retards gastric emptying. Life Sci.48, 123–134 (1991).
  • Wolfe MM, Nompleggi DJ. Cytokine inhibition of gastric acid secretion – a little goes a long way. Gastroenterology102, 2177–2178 (1992).
  • Beales IL, Calam J. Interleukin 1 β and tumour necrosis factor α inhibit acid secretion in cultured rabbit parietal cells by multiple pathways. Gut 42, 227–234 (1998).
  • El-Omar EM, Oien K, El Nujumi A et al.Helicobacter pylori infection and chronic gastric acid hyposecretion. Gastroenterology113, 15–24 (1997).
  • El-Omar EM, Penman ID, Ardill JE et al.Helicobacter pylori infection and abnormalities of acid secretion in patients with duodenal ulcer disease. Gastroenterology109, 681–691 (1995).
  • McColl KE, El-Omar E, Gillen D. Helicobacter pylori gastritis and gastric physiology. Gastroenterol. Clin. North Am.29, 687–703 (2000).
  • Danon SJ, O’Rourke JL, Moss ND et al. The importance of local acid production in the distribution of Helicobacter felis in the mouse stomach. Gastroenterology108, 1386–1395 (1995).
  • Lundell L, Havu N, Miettinen P et al. Changes of gastric mucosal architecture during long-term omeprazole therapy: results of a randomized clinical trial. Aliment Pharmacol. Ther.23, 639–647 (2006).
  • Kuipers EJ. Proton pump inhibitors and gastric neoplasia. Gut55, 1217–1221 (2006).
  • Kuipers EJ, Klinkenberg-Knol EC, Meuwissen SG. Omeprazole and accelerated onset of atrophic gastritis. Gastroenterology118, 239–242 (2000).
  • Malaty HM, Engstrand L, Pedersen NL et al.Helicobacter pylori infection: genetic and environmental influences. A study of twins. Ann. Intern. Med.120, 982–986 (1994).
  • Tseng FC, Brown EE, Maiese EM et al. Polymorphisms in cytokine genes and risk of Helicobacter pylori infection among Jamaican children. Helicobacter11, 425–430 (2006).
  • Liou JM, Lin JT, Wang HP et al.IL-1B-511 C-->T polymorphism is associated with increased host susceptibility to Helicobacter pylori infection in Chinese. Helicobacter12, 142–149 (2007).
  • Parkin DM, Bray F, Ferlay J et al. Global cancer statistics, 2002. CA Cancer J. Clin.55, 74–108 (2005).
  • Graham DY, Yamaoka Y. Disease-specific Helicobacter pylori virulence factors: the unfulfilled promise. Helicobacter5(Suppl. 1), S3–S9 (2000).
  • Dinarello CA. Biologic basis for interleukin-1 in disease. Blood87, 2095–2147 (1996).
  • El-Omar EM. The importance of interleukin 1β in Helicobacter pylori associated disease. Gut48, 743–747 (2001).
  • Bidwell J, Keen L, Gallagher G et al. Cytokine gene polymorphism in human disease: on-line databases, supplement 1. Genes Immun.2, 61–70 (2001).
  • El-Omar EM, Carrington M, Chow WH et al. Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature404, 398–402 (2000).
  • El-Omar EM, Rabkin CS, Gammon MD et al. Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms. Gastroenterology124, 1193–1201 (2003).
  • Machado JC, Pharoah P, Sousa S et al. Interleukin 1B and interleukin 1RN polymorphisms are associated with increased risk of gastric carcinoma. Gastroenterology121, 823–829 (2001).
  • Figueiredo C, Machado JC, Pharoah P et al.Helicobacter pylori and interleukin 1 genotyping: an opportunity to identify high-risk individuals for gastric carcinoma. J. Natl Cancer Inst.94, 1680–1687 (2002).
  • Machado JC, Figueiredo C, Canedo P et al. A proinflammatory genetic profile increases the risk for chronic atrophic gastritis and gastric carcinoma. Gastroenterology125, 364–371 (2003).
  • Rad R, Prinz C, Neu B et al. Synergistic effect of Helicobacter pylori virulence factors and interleukin-1 polymorphisms for the development of severe histological changes in the gastric mucosa. J. Infect. Dis.188, 272–281 (2003).
  • Palli D, Saieva C, Luzzi I et al. Interleukin-1 gene polymorphisms and gastric cancer risk in a high-risk Italian population. Am. J. Gastroenterol.100, 1941–1948 (2005).
  • Furuta T, El-Omar EM, Xiao F et al. Interleukin 1β polymorphisms increase risk of hypochlorhydria and atrophic gastritis and reduce risk of duodenal ulcer recurrence in Japan. Gastroenterology123, 92–105 (2002).
  • Zeng ZR, Hu PJ, Hu S et al. Association of interleukin 1B gene polymorphism and gastric cancers in high and low prevalence regions in China. Gut52, 1684–1689 (2003).
  • Lee KA, Ki CS, Kim HJ et al. Novel interleukin 1β polymorphism increased the risk of gastric cancer in a Korean population. J. Gastroenterol.39, 429–433 (2004).
  • Chang YW, Jang JY, Kim NH et al. Interleukin-1B (IL-1B) polymorphisms and gastric mucosal levels of IL-1β cytokine in Korean patients with gastric cancer. Int. J. Cancer114, 465–471 (2005).
  • Yang J, Hu Z, Xu Y et al. Interleukin-1B gene promoter variants are associated with an increased risk of gastric cancer in a Chinese population. Cancer Lett.215, 191–198 (2004).
  • Chen HM, Wilkins LM, Aziz N et al. Single nucleotide polymorphisms in the human interleukin-1B gene affect transcription according to haplotype context. Hum. Mol. Genet.15, 519–529 (2006).
  • Lee KA, Park JH, Sohn TS et al. Interaction of polymorphisms in the Interleukin 1B-31 and general transcription factor 2A1 genes on the susceptibility to gastric cancer. Cytokine38, 96–100 (2007).
  • Shen J, Arnett DK, Peacock JM et al. Interleukin1β genetic polymorphisms interact with polyunsaturated fatty acids to modulate risk of the metabolic syndrome. J. Nutr.137, 1846–1851 (2007).
  • Tu S, Cui G, Takaishi S et al. Overexpression of human interleukin-1 β in transgenic mice results in spontaneous gastric inflammation and carcinogenesis. Gastroenterology128(4 Suppl. 2), A62 (2005).
  • Lu W, Pan K, Zhang L et al. Genetic polymorphisms of interleukin (IL)-1B, IL-1RN, IL-8, IL-10 and tumor necrosis factor α and risk of gastric cancer in a Chinese population. Carcinogenesis26, 631–636 (2005).
  • Taguchi A, Ohmiya N, Shirai K et al. Interleukin-8 promoter polymorphism increases the risk of atrophic gastritis and gastric cancer in Japan. Cancer Epidemiol. Biomarkers Prev.14, 2487–2493 (2005).
  • Lee WP, Tai DI, Lan KH et al. The -251T allele of the interleukin-8 promoter is associated with increased risk of gastric carcinoma featuring diffuse-type histopathology in Chinese population. Clin. Cancer Res.11, 6431–6441 (2005).
  • Ohyauchi M, Imatani A, Yonechi M et al. The polymorphism interleukin 8 -251 A/T influences the susceptibility of Helicobacter pylori related gastric diseases in the Japanese population. Gut54, 330–335 (2005).
  • Kuipers EJ. Review article: exploring the link between Helicobacter pylori and gastric cancer. Aliment Pharmacol. Ther.13(Suppl. 1), 3–11 (1999).
  • Segal ED, Lange C, Covacci A et al. Induction of host signal transduction pathways by Helicobacter pylori. Proc. Natl Acad. Sci. USA94, 7595–7599 (1997).
  • Su B, Ceponis PJ, Lebel S et al.Helicobacter pylori activates Toll-like receptor 4 expression in gastrointestinal epithelial cells. Infect. Immun.71, 3496–3502 (2003).
  • Pasare C, Medzhitov R. Toll-like receptors: linking innate and adaptive immunity. Adv. Exp. Med. Biol.560, 11–18 (2005).
  • Takeda K, Akira S. Toll-like receptors in innate immunity. Int. Immunol.17, 1–14 (2005).
  • Arbour NC, Lorenz E, Schutte BC et al.TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. Nat. Genet.25, 187–191 (2000).
  • Franchimont D, Vermeire S, El Housni H et al. Deficient host–bacteria interactions in inflammatory bowel disease? The Toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn’s disease and ulcerative colitis. Gut53, 987–992 (2004).
  • Lorenz E, Mira JP, Frees KL et al. Relevance of mutations in the TLR4 receptor in patients with Gram-negative septic shock. Arch. Intern. Med.162, 1028–1032 (2002).
  • Kiechl S, Lorenz E, Reindl M et al. Toll-like receptor 4 polymorphisms and atherogenesis. N. Engl. J. Med.347, 185–192 (2002).
  • Higgins SC, Lavelle EC, McCann C et al. Toll-like receptor 4-mediated innate IL-10 activates antigen-specific regulatory T cells and confers resistance to Bordetella pertussis by inhibiting inflammatory pathology. J. Immunol.171, 3119–3127 (2003).
  • Hold GL, Rabkin CS, Chow WH et al. A functional polymorphism of Toll-like receptor 4 gene increases risk of gastric carcinoma and its precursors. Gastroenterology132, 905–912 (2007).
  • Sanduleanu S, Jonkers D, De Bruine A et al. Double gastric infection with Helicobacter pylori and non-Helicobacter pylori bacteria during acid-suppressive therapy: increase of pro-inflammatory cytokines and development of atrophic gastritis. Aliment. Pharmacol. Ther.15, 1163–1175 (2001).
  • Zavros Y, Rieder G, Ferguson A et al. Genetic or chemical hypochlorhydria is associated with inflammation that modulates parietal and G-cell populations in mice. Gastroenterology122, 119–133 (2002).
  • Baccarelli A, Hou L, Chen J et al. Mannose-binding lectin-2 genetic variation and stomach cancer risk. Int. J. Cancer119, 1970–1975 (2006).
  • Zanke BW, Greenwood CM, Rangrej J et al. Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24. Nat. Genet.39, 989–994 (2007).
  • Haiman CA, Le Marchand L, Yamamato J et al. A common genetic risk factor for colorectal and prostate cancer. Nat. Genet.39, 954–956 (2007).
  • Tomlinson I, Webb E, Carvajal-Carmona L et al. A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21. Nat. Genet.39, 984–988 (2007).

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