Optimizing lesion detection in small-bowel capsule endoscopy: from present problems to future solutions

References

• Koulaouzidis A, Rondonotti E, Karargyris A. Small-bowel capsule endoscopy: a ten-point contemporary review. World J Gastroenterol 2013;19:3726-46
   PubMed Web of Science ®Google Scholar
• Iddan G, Meron G, Glukhovsky A, et al. Wireless capsule endoscopy. Nature 2000;405:417
   PubMed Web of Science ®Google Scholar
• Eliakim R. Video capsule endoscopy of the small bowel. Curr Opin Gastroenterol 2013;29:133-9
   PubMed Web of Science ®Google Scholar
• ASGE Technology Committee. Wang A, Banerjee S, Barth BA, et al. Wireless capsule endoscopy. Gastrointest Endosc 2013;78:805-15
   PubMed Web of Science ®Google Scholar
• Ladas SD, Triantafyllou K, Spada C, et al. ESGE Clinical Guidelines Committee. European Society of Gastrointestinal Endoscopy (ESGE): recommendations (2009) on clinical use of video capsule endoscopy to investigate small-bowel, esophageal and colonic diseases. Endoscopy 2010;42:220-7
   PubMed Web of Science ®Google Scholar
• Sidhu R, Sanders DS, Morris AJ, et al. Guidelines on small bowel enteroscopy and capsule endoscopy in adults. Gut 2008;57:125-36
   PubMed Web of Science ®Google Scholar
• Eliakim R, Carter D. Endoscopic assessment of the small bowel. Dig Dis 2013;31:194-8
   PubMed Web of Science ®Google Scholar
• Fisher LR, Hasler WL. New vision in video capsule endoscopy: current status and future directions. Nat Rev Gastroenterol Hepatol 2012;9:392-405
   PubMed Web of Science ®Google Scholar
• Swain P. At a watershed? Technical developments in wireless capsule endoscopy. J Dig Dis 2010;11:259-65
   PubMed Web of Science ®Google Scholar
• Girelli CM, Porta P, Colombo E, et al. Development of a novel index to discriminate bulge from mass on small-bowel capsule endoscopy. Gastrointest Endosc 2011;74:1067-74; quiz 1115.e1-5
   PubMed Web of Science ®Google Scholar
• Lewis BS. How to read wireless capsule endoscopic images: tips of the trade. Gastrointest Endosc Clin N Am 2004;14:11-16
   PubMedGoogle Scholar
• Adler SN, Metzger YC, Roesch T. The flat polyp: does too much flattening occur with full air insufflation on colonoscopy? Endoscopy 2010;42(Suppl 2)):E167-8
   Google Scholar
• Woods SP, Constandinou TG. Wireless capsule endoscope for targeted drug delivery: mechanics and design considerations. IEEE Trans Biomed Eng 2013;60:945-53
   PubMed Web of Science ®Google Scholar
• Karargyris A, Koulaouzidis A. OdoCapsule: next generation wireless capsule endoscopy with accurate localization and video stabilization. IEEE Trans Biomed Eng 2014; Under review
   Web of Science ®Google Scholar
• Filip D. Self-stabilising capsule endoscope for early detection and biopsy of colonic polyps. Thesis for PhD, Dept of Electrical and Computer Engineering Calgary, Alberta, Canada 2013. Available from: http://theses.ucalgary.ca/handle/11023/495
   Google Scholar
• Kopylov U, Papageorgiou NP, Nadler M, et al. Head or tail: the orientation of the small bowel capsule endoscope movement in the small bowel. Dig Dis Sci 2012;57:694-8
   PubMed Web of Science ®Google Scholar
• Koulaouzidis A, Douglas S, Plevris JN. Heads or tail orientation in small-bowel capsule endoscopy: 2 capsule models with 2 reviewers. Dig Dis Sci 2012;57:1102-3
   PubMed Web of Science ®Google Scholar
• Adler SN, Metzger YC. Heads or tails, does it make a difference? Capsule endoscope direction in small bowel studies is important. Endoscopy 2007;39:910-12
   PubMed Web of Science ®Google Scholar
• Metzger YC, Adler SN, Bar-Gil Shitrit A, et al. Comparison of a new PillCam™ SB2 video capsule versus the standard PillCam™ SB for detection of small bowel disease. Reports in Medical Imaging 2009;2:7-11
   Google Scholar
• Koulaouzidis A. Upper esophageal images and Z-line detection with 2 different small-bowel capsule systems. World J Gastroenterol 2012;18:6003-4
   PubMed Web of Science ®Google Scholar
• Chung JW, Hwang HJ, Chung MJ, et al. Safety of capsule endoscopy using human body communication in patients with cardiac devices. Dig Dis Sci 2012;57:1719-23
   PubMed Web of Science ®Google Scholar
• Bandorski D, Höltgen R, Stunder D, et al. Capsule endoscopy in patients with cardiac pacemakers, implantable cardioverter defibrillators and left heart assist devices. Ann Gastroenterol 2014;27:3-8
   PubMedGoogle Scholar
• Choi EH, Mergener K, Semrad C, et al. A multicenter, prospective, randomized comparison of a novel signal transmission capsule endoscope to an existing capsule endoscope. Gastrointest Endosc 2013;78:325-32
   PubMed Web of Science ®Google Scholar
• Drew K, McAlindon ME, Sanders DS, et al. The nurse endoscopist: moving ahead with time. Gastroenterol Nurs 2013;36:209-13
   PubMed Web of Science ®Google Scholar
• Koulaouzidis A, Pendlebury J, Douglas S, et al. Aspiration of video capsule: rare but potentially life-threatening complication to include in your consent form. Am J Gastroenterol 2009;104:1602-3
   PubMed Web of Science ®Google Scholar
• Rajan E, Iyer PG, Oxentenko AS, et al. Training in small-bowel capsule endoscopy: assessing and defining competency. Gastrointest Endosc 2013;78:617-22
   PubMed Web of Science ®Google Scholar
• Krupinski EA, Graham AR, Weinstein RS. Characterizing the development of visual search expertise in pathology residents viewing whole slide images. Hum Pathol 2013;44:357-64
   PubMed Web of Science ®Google Scholar
• Cave DR. Reading wireless video capsule endoscopy. Gastrointest Endosc Clin N Am 2004;14:17-13
   PubMedGoogle Scholar
• Krupinski EA, Tillack AA, Richter L, et al. Eye-movement study and human performance using telepathology virtual slides: implications for medical education and differences with experience. Hum Pathol 2006;37(12):1543-56
   PubMed Web of Science ®Google Scholar
• Helle L, Nivala M, Kronqvist P, et al. Do prior knowledge, personality and visual perceptual ability predict student performance in microscopic pathology? Med Educ 2010;44:621-9
   PubMed Web of Science ®Google Scholar
• Zheng Y, Hawkins L, Wolff J, et al. Detection of lesions during capsule endoscopy: physician performance is disappointing. Am J Gastroenterol 2012;107:554-60
   PubMed Web of Science ®Google Scholar
• Lo SK. How should we do capsule reading? Tech Gastrointest Endosc 2006;8:146-8
   Google Scholar
• Rondonotti E, Soncini M, Girelli CM, et al. AIGO, SIED and SIGE Lombardia. Can we improve the detection rate and interobserver agreement in capsule endoscopy? Dig Liver Dis 2012;44:1006-26
   PubMedGoogle Scholar
• Mishkin DS, Chuttani R, Croffie J, et al. Technology Assessment Committee, American Society for Gastrointestinal Endoscopy. ASGE Technology Status Evaluation Report: wireless capsule endoscopy. Gastrointest Endosc 2006;63:539-45
   PubMed Web of Science ®Google Scholar
• Fleischer DE. Capsule endoscopy: the voyage is fantastic–will it change what we do? Gastrointest Endosc 2002;56:452-6
   PubMed Web of Science ®Google Scholar
• Galinsky T, Rosa R, Warm J, et al. Psychophysical determinants in sustained attention. Hum Factors 1993;35:603-14
   PubMed Web of Science ®Google Scholar
• Butterly L, Robinson CM, Anderson JC, et al. Serrated and adenomatous polyp detection increases with longer withdrawal time: results from the New Hampshire colonoscopy registry. Am J Gastroenterol 2014;109:417-26
   PubMed Web of Science ®Google Scholar
• Lee TJ, Rees CJ, Blanks RG, et al. Colonoscopic factors associated with adenoma detection in a national colorectal cancer screening program. Endoscopy 2014;46:203-11
   PubMed Web of Science ®Google Scholar
• Spyrou E, Iakovidis DK. Video-based measurements for wireless capsule endoscope IOP publishing; tracking. Meas Sci Technol 2014;25:015002; 14pp
   Web of Science ®Google Scholar
• Korean Gut Image Study Group. Lim YJ, Joo YS, Jung DY, et al. Learning curve of capsule endoscopy. Clin Endosc 2013;46:633-6
   PubMedGoogle Scholar
• Jensen MD, Nathan T, Kjeldsen J. Inter-observer agreement for detection of small bowel Crohn’s disease with capsule endoscopy. Scand J Gastroenterol 2010;45:878-84
   PubMed Web of Science ®Google Scholar
• Postgate A, Haycock A, Thomas-Gibson S, et al. Computer-aided learning in capsule endoscopy leads to improvement in lesion recognition ability. Gastrointest Endosc 2009;70:310-16
   PubMed Web of Science ®Google Scholar
• Shiotani A, Honda K, Kawakami M, et al. Evaluation of RAPID(®) 5 Access software for examination of capsule endoscopies and reading of the capsule by an endoscopy nurse. J Gastroenterol 2011;46:138-42
   PubMed Web of Science ®Google Scholar
• Brock AS, Freeman J, Roberts J, et al. A resource-efficient tool for training novices in wireless capsule endoscopy. Gastroenterol Nurs 2012;35:317-21
   PubMed Web of Science ®Google Scholar
• Dokoutsidou H, Karagiannis S, Giannakoulopoulou E, et al. A study comparing an endoscopy nurse and an endoscopy physician in capsule endoscopy interpretation. Eur J Gastroenterol Hepatol 2011;23:166-70
   PubMed Web of Science ®Google Scholar
• Shiotani A, Honda K, Kawakami M, et al. Analysis of small-bowel capsule endoscopy reading by using quickview mode: training assistants for reading may produce a high diagnostic yield and save time for physicians. J Clin Gastroenterol 2012;46:e92-5
   PubMed Web of Science ®Google Scholar
• Riphaus A, Richter S, Vonderach M, et al. Capsule endoscopy interpretation by an endoscopy nurse - a comparative trial. Z Gastroenterol 2009;47:273-6
   PubMed Web of Science ®Google Scholar
• Postgate A, Haycock A, Fitzpatrick A, et al. How should we train capsule endoscopy? A pilot study of performance changes during a structured capsule endoscopy training program. Dig Dis Sci 2009;54:1672-9
   PubMed Web of Science ®Google Scholar
• Levinthal GN, Burke CA, Santisi JM. The accuracy of an endoscopy nurse in interpreting capsule endoscopy. Am J Gastroenterol 2003;98:2669-71
   PubMed Web of Science ®Google Scholar
• Fernández-Urién I, Espinet E, Pérez N, et al. [Capsule endoscopy interpretation: the role of physician extenders]. Rev Esp Enferm Dig 2008;100:219-24
   PubMed Web of Science ®Google Scholar
• Sidhu R, Sanders DS, Kapur K, et al. Capsule endoscopy: is there a role for nurses as physician extenders? Gastroenterol Nurs 2007;30:45-8
   PubMed Web of Science ®Google Scholar
• Bossa F, Cocomazzi G, Valvano MR, et al. Detection of abnormal lesions recorded by capsule endoscopy. A prospective study comparing endoscopist’s and nurse’s accuracy. Dig Liver Dis 2006;38:599-602
   PubMedGoogle Scholar
• Niv Y, Niv G. Capsule endoscopy examination–preliminary review by a nurse. Dig Dis Sci 2005;50:2121-4
   PubMed Web of Science ®Google Scholar
• Jang BI, Lee SH, Moon JS, et al. Inter-observer agreement on the interpretation of capsule endoscopy findings based on capsule endoscopy structured terminology: a multicenter study by Korean Gut Image Study Group. Scand J Gastroenterol 2010;45:370-4
   PubMed Web of Science ®Google Scholar
• Buscaglia JM. "Drivers ed" with a road test for the capsule endoscopist. Gastrointest Endosc 2013;78:623-4
   PubMed Web of Science ®Google Scholar
• Faigel DO, Baron TH, Adler DG, et al. ASGE. ASGE guideline: guidelines for credentialing and granting privileges for capsule endoscopy. Gastrointest Endosc 2005;61:503-5
   PubMed Web of Science ®Google Scholar
• Than TD, Alici G, Zhou H, et al. A review of localization systems for robotic endoscopic capsules. IEEE Trans Biomed Eng 2012;59:2387-99
   PubMed Web of Science ®Google Scholar
• Fischer D, Schreiber R, Levi D, et al. Capsule endoscopy: the localization system. Gastrointest Endosc Clin N Am 2004;14:25-31
   PubMedGoogle Scholar
• Marya N, Karellas A, Foley A, et al. Computerized 3-dimensional localization of a video capsule in the abdominal cavity: validation by digital radiography. Gastrointest Endosc 2014;79:669-74
   PubMed Web of Science ®Google Scholar
• Karargyris A, Koulaouzidis A. Capsule-odometer: a concept to improve accurate lesion localization. World J Gastroenterol 2013;19:5943-6
   PubMed Web of Science ®Google Scholar
• Karargyris A, Bourbakis N. Wireless capsule endoscopy and endoscopic imaging: a survey on various methodologies presented. IEEE Eng Med Biol Mag 2010;29:72-83
   PubMedGoogle Scholar
• Iakovidis DK, Spyrou E, Diamantis D, et al. Capsule endoscope localization based on visual features. In Proceedings of IEEE International Conference on Bioinformatics and Bioengineering (BIBE), Chania, Greece, 2013
   Google Scholar
• Scaramuzza D, Fraundorfer F. Visual odometry, Part I: the first 30 years and fundamentals. IEEE Robot Autom Mag 2011;80-92
   Web of Science ®Google Scholar
• Koulaouzidis A, Rondonotti E, Giannakou A, et al. Diagnostic yield of small-bowel capsule endoscopy in patients with iron-deficiency anemia: a systematic review. Gastrointest Endosc 2012;76:983-92
   PubMed Web of Science ®Google Scholar
• Liao Z, Gao R, Xu C, et al. Indications and detection, completion, and retention rates of small-bowel capsule endoscopy: a systematic review. Gastrointest Endosc 2010;71:280-6
   PubMed Web of Science ®Google Scholar
• Rondonotti E, Marmo R, Petracchini M, et al. The American Society for Gastrointestinal Endoscopy (ASGE) diagnostic algorithm for obscure gastrointestinal bleeding: eight burning questions from everyday clinical practice. Dig Liver Dis 2013;45:179-85
   PubMedGoogle Scholar
• Appleyard M, Fireman Z, Glukhovsky A, et al. A randomized trial comparing wireless capsule endoscopy with push enteroscopy for the detection of small-bowel lesions. Gastroenterology 2000;119:1431-8
   PubMed Web of Science ®Google Scholar
• Cass OW. Is half-knowledge worse than ignorance? Gastrointest Endosc 2006;64:542-3
   PubMed Web of Science ®Google Scholar
• Koulaouzidis A, Plevris JN. Detection of the ampulla of Vater in small bowel capsule endoscopy: experience with two different systems. J Dig Dis 2012;13:621-7
   PubMed Web of Science ®Google Scholar
• Rondonotti E, Koulaouzidis A, Karargyris A, et al. Utility of three-dimensional image reconstruction in the diagnosis of small-bowel masses in capsule endoscopy. Gastrointest Endosc 2014. [Epub ahead of print]
   Google Scholar
• Friedrich K, Gehrke S, Stremmel W, et al. First clinical trial of a newly developed capsule endoscope with panoramic side view for small bowel: a pilot study. J Gastroenterol Hepatol 2013;28:1496-501
   PubMed Web of Science ®Google Scholar
• Koulaouzidis A, Dabos KJ. Looking forwards: not necessarily the best in capsule endoscopy? Ann Gastroenterol 2013;26:365-7
   PubMedGoogle Scholar
• Hale MF, Drew K, Baldacchino T, et al. Gastroscopy without a Gastroscope! feasibility in a porcine model using a magnetic capsule. Gut 2013;62:A156
   Web of Science ®Google Scholar
• Swain P. The future of wireless capsule endoscopy. World J Gastroenterol 2008;14:4142-5
   PubMed Web of Science ®Google Scholar
• Rokkas T, Papaxoinis K, Triantafyllou K, et al. Does purgative preparation influence the diagnostic yield of small bowel video capsule endoscopy?: a meta-analysis. Am J Gastroenterol 2009;104:219-27
   PubMed Web of Science ®Google Scholar
• Mergener K, Ponchon T, Gralnek I, et al. Literature review and recommendations for clinical application of small-bowel capsule endoscopy, based on a panel discussion by international experts. Consensus statements for small-bowel capsule endoscopy, 2006/2007. Endoscopy 2007;39:895-909; Erratum in: Endoscopy 2007;39:1105
   PubMed Web of Science ®Google Scholar
• Yazici C, Losurdo J, Brown MD, et al. Inpatient capsule endoscopy leads to frequent incomplete small bowel examinations. World J Gastroenterol 2012;18:5051-7
   PubMed Web of Science ®Google Scholar
• Triantafyllou K, Papadopoulos AA, Kalantzis N, et al. Diabetes mellitus is a risk factor for incomplete small-bowel capsule endoscopy. Gastrointest Endosc 2009;69:1408-9
   PubMed Web of Science ®Google Scholar
• Westerhof J, Weersma RK, Koornstra JJ. Risk factors for incomplete small-bowel capsule endoscopy. Gastrointest Endosc 2009;69:74-80
   PubMed Web of Science ®Google Scholar
• Shibuya T, Mori H, Takeda T, et al. The relationship between physical activity level and completion rate of small bowel examination in patients undergoing capsule endoscopy. Intern Med 2012;51:997-1001
   PubMed Web of Science ®Google Scholar
• Fatima H, Rex DK, Rothstein R, et al. Cecal insertion and withdrawal times with wide-angle versus standard colonoscopes: a randomized controlled trial. Clin Gastroenterol Hepatol 2008;6:109-14
   PubMed Web of Science ®Google Scholar
• Villa F, Signorelli C, Rondonotti E, et al. Preparations and prokinetics. Gastrointest Endosc Clin N Am 2006;16:211-20
   PubMedGoogle Scholar
• Koulaouzidis A, Dimitriadis S, Douglas S, et al. The use of Domperidone increases the completion rate of small bowel capsule endoscopy but does this come at the expense of diagnostic yield? J Clin Gastroenterol 2014. [ Epub ahead of print]
   Web of Science ®Google Scholar
• Champion MC, Hartnett M, Yen M. Domperidone, a new dopamine antagonist. CMAJ 1986;135:457-61
   PubMed Web of Science ®Google Scholar
• Ou G, Svarta S, Chan C, et al. The effect of chewing gum on small-bowel transit time in capsule endoscopy: a prospective, randomized trial. Gastrointest Endosc 2014;79:630-6
   PubMed Web of Science ®Google Scholar
• Dabos KJ, Giannakou A, Koulaouzidis A. Chewing gum and completion rate in small-bowel capsule endoscopy: meta-analyzing the data. Gastrointest Endosc 2014;79(6):1032-4
   PubMed Web of Science ®Google Scholar
• de Franchis R, Avgerinos A, Barkin J, et al. ICCE. ICCE consensus for bowel preparation and prokinetics. Endoscopy 2005;37:1040-5
   PubMed Web of Science ®Google Scholar
• Koulaouzidis A, Giannakou A, Yung DE, et al. Do prokinetics influence the completion rate in small-bowel capsule endoscopy? A systematic review and meta-analysis. Curr Med Res Opin 2013;29:1171-85
   PubMed Web of Science ®Google Scholar
• Koulaouzidis A, Giannakou A, Plevris JN. Prokinetics in small-bowel capsule endoscopy: smart use is the key. Eur J Gastroenterol Hepatol 2014;26:492-3
   PubMed Web of Science ®Google Scholar
• Pohl J, Nguyen-Tat M, Pech O, et al. Computed virtual chromoendoscopy for classification of small colorectal lesions: a prospective comparative study. Am J Gastroenterol 2008;103:562-9
   PubMed Web of Science ®Google Scholar
• Pohl J, Aschmoneit I, Schuhmann S, et al. Computed image modification for enhancement of small-bowel surface structures at video capsule endoscopy. Endoscopy 2010;42:490-2
   PubMed Web of Science ®Google Scholar
• Imagawa H, Oka S, Tanaka S, et al. Improved visibility of lesions of the small intestine via capsule endoscopy with computed virtual chromoendoscopy. Gastrointest Endosc 2011;73:299-306
   PubMed Web of Science ®Google Scholar
• Spada C, Hassan C, Costamagna G. Virtual chromoendoscopy: will it play a role in capsule endoscopy? Dig Liver Dis 2011;43:927-8
   PubMedGoogle Scholar
• Aihara H, Ikeda K, Tajiri H. Image-enhanced capsule endoscopy based on the diagnosis of vascularity when using a new type of capsule. Gastrointest Endosc 2011;73:1274-9
   PubMed Web of Science ®Google Scholar
• Krystallis C, Koulaouzidis A, Douglas S, et al. Chromoendoscopy in small bowel capsule endoscopy: blue mode or Fuji intelligent colour enhancement? Dig Liver Dis 2011;43(12):953-7
   PubMedGoogle Scholar
• Koulaouzidis A, Douglas S, Plevris JN. Blue mode does not offer any benefit over white light when calculating Lewis score in small-bowel capsule endoscopy. World J Gastrointest Endosc 2012;4:33
   PubMedGoogle Scholar
• Koulaouzidis A, Smirnidis A, Douglas S, et al. QuickView in small-bowel capsule endoscopy is useful in certain clinical settings, but QuickView with Blue Mode is of no additional benefit. Eur J Gastroenterol Hepatol 2012;24:1099-104
   PubMed Web of Science ®Google Scholar
• Westerhof J, Koornstra JJ, Weersma RK. Can we reduce capsule endoscopy reading times? Gastrointest Endosc 2009;69:497-502
   PubMed Web of Science ®Google Scholar
• Saurin JC, Lapalus MG, Cholet F, et al. French Society of Digestive Endoscopy (SFED). Can we shorten the small-bowel capsule reading time with the "Quick-view" image detection system? Dig Liver Dis 2012;44:477-81
   PubMedGoogle Scholar
• Halling ML, Nathan T, Kjeldsen J, et al. High sensitivity of quick view capsule endoscopy for detection of small bowel Crohn’s disease. J Gastroenterol Hepatol 2014;29(5):992-6
   PubMed Web of Science ®Google Scholar
• Farnbacher MJ, Krause HH, Hagel AF, et al. QuickView video preview software of colon capsule endoscopy: reliability in presenting colorectal polyps as compared to normal mode reading. Scand J Gastroenterol 2014;49:339-46
   PubMed Web of Science ®Google Scholar
• Koulaouzidis A, Douglas S. Capsule endoscopy in clinical practice: concise up-to-date overview. Clin Exp Gastroenterol 2009;2:111-16
   PubMedGoogle Scholar
• Buscaglia JM, Kapoor S, Clarke JO, et al. Enhanced diagnostic yield with prolonged small bowel transit time during capsule endoscopy. Int J Med Sci 2008;5:303-8
   PubMedGoogle Scholar
• Koulaouzidis A, Karargyris A. Three-dimensional image reconstruction in capsule endoscopy. World J Gastroenterol 2012;18:4086-90
   PubMed Web of Science ®Google Scholar
• Karargyris A, Bourbakis N. Three-dimensional reconstruction of the digestive wall in capsule endoscopy videos using elastic video interpolation. IEEE Trans Med Imaging 2011;30:957-71
   PubMed Web of Science ®Google Scholar
• Kolar A, Romain O, Ayoub J, et al. Prototype of video endoscopic capsule with 3-d imaging capabilities. IEEE Trans Biomed Circuits Syst 2010;4:239-49
   PubMed Web of Science ®Google Scholar
• Horn BKP. Shape from shading: a method for obtaining the shape of a smooth opaque object from one view. PhD thesis, MIT, 1970. Available from: http://dspace.mit.edu/handle/1721.1/6885
   Google Scholar
• Karargyris A, Rondonotti E, Mandelli G, et al. Evaluation of 4 three-dimensional representation algorithms in capsule endoscopy images. World J Gastroenterol 2013;19:8028-33
   PubMed Web of Science ®Google Scholar
• Koulaouzidis A, Karargyris A. Use of enhancement algorithm to suppress reflections in 3-D reconstructed capsule endoscopy images. World J Gastrointest Endosc 2013;5:465-7
   PubMedGoogle Scholar
• Koulaouzidis A, Karargyris A, Rondonotti E, et al. Three-dimensional representation software as image enhancement tool in small-bowel capsule endoscopy: a feasibility study. Dig Liver Dis 2013;45:909-14
   PubMedGoogle Scholar
• Ghoshal UC. Small bowel endoscopy in 2013: the reality and the potential. Nat Rev Gastroenterol Hepatol 2014;11:86-7
   PubMed Web of Science ®Google Scholar
• Girelli CM, Porta P. Bulge or mass? A diagnostic dilemma of capsule endoscopy. Endoscopy 2008;40:703-4
   PubMed Web of Science ®Google Scholar
• Postgate A, Tekkis P, Fitzpatrick A, et al. The impact of experience on polyp detection and sizing accuracy at capsule endoscopy: implications for training from an animal model study. Endoscopy 2008;40:496-501
   PubMed Web of Science ®Google Scholar
• Karargyris A, Karargyris O, Bourbakis N. 3D Representation of the Digestive Tract Surface in Wireless Capsule Endoscopy Videos. BioInformatics and BioEngineering (BIBE), 2010 IEEE International Conference; 31 May 2010–3 June 2010. p. 279-80
   Google Scholar
• Ciuti G, Visentini-Scarzanella M, Dore A, et al. Intra-operative monocular 3D reconstruction for image-guided navigation in active locomotion capsule endoscopy. Biomedical Robotics and Biomechatronics (BioRob), 2012 4th IEEE RAS & EMBS International Conference; 24-27 June 2012. p. 768-774
   Google Scholar
• Prasath VBS, Figueiredo IN, Figueiredo PN, et al. Mucosal region detection and 3D reconstruction in wireless capsule endoscopy videos using active contours. Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE; 28 August 2012–1 September 2012. p. 4014-4017
   Google Scholar
• Sun B, Liu L, Hu C, et al. 3D reconstruction based on Capsule Endoscopy image sequences. Audio Language and Image Processing (ICALIP), 2010 International Conference; 23-25 November 2010. p. 607-612
   Google Scholar
• Fan Y, Meng MQH, Li B. 3D reconstruction of wireless capsule endoscopy images, Engineering in Medicine and Biology Society (EMBC). 2010 Annual International Conference of the IEEE. 31 August 2010–4 September 2010. p. 5149-52
   Google Scholar
• Iakovidis DK, Spyrou E, Diamantis D. Efficient Homography-Based Video Visualization for Wireless Capsule Endoscopy, In Proceedings of, IEEE International Conference on Bioinformatics and Bioengineering (BIBE), Chania, Greece, 2013
   Google Scholar
• Spyrou E, Diamantis D, Iakovidis DK. Panoramic Visual Summaries for Efficient Reading of Capsule Endoscopy Videos,. In Proceedings of, IEEE International Workshop on Semantic and Social Media Adaptation and Personalization (SMAP), Bayonne, France, 2013. p. 41-6
   Google Scholar
• Szeliski R, Image alignment and stitching: a tutorial. Foundations and trends in computer graphics and vision. 2006. p. 1-104
   Google Scholar
• Yi S, Xie J, Mui P, Leighton JA. “Achieving real-time capsule endoscopy (CE) video visualization through panoramic imaging,” IS&T/SPIE Electronic Imaging. 2013. p. 86560I
   Google Scholar
• Soper TD, Porter MP, Seibel EJ. Surface mosaics of the bladder reconstructed from endoscopic video for automated surveillance. IEEE Trans Biomed Eng 2012;59(6):1670-80
   PubMed Web of Science ®Google Scholar
• Tanaka M, Kidoh Y, Kamei M, et al. A new instrument for measurement of gastrointestinal mucosal color. Dig Endosc 1996;8(2):139-46
   Google Scholar
• Kudo S, Kashida H, Tamura T, et al. Colonoscopic diagnosis and management of nonpolypoid early colorectal cancer. World J Surg 2000;24(9):1081-90
   PubMed Web of Science ®Google Scholar
• Theodoridis S, Koutroumbas K. Pattern Recognition. 4th edition. Elsevier; 2008
   Google Scholar
• Karkanis SA, Iakovidis DK, Maroulis DE, et al. Computer aided tumor detection in endoscopic video using color wavelet features. IEEE Trans Inf Technol Biomed 2003;7:141-52
   PubMedGoogle Scholar
• Liedlgruber M, Uhl A. Computer-aided decision support systems for endoscopy in the gastrointestinal tract: A review. IEEE Rev Biomed Eng 2011;4:73-88
   PubMedGoogle Scholar
• Sainju S, Bui FM, Wahid KA. Automated bleeding detection in capsule endoscopy videos using statistical features and region growing. J Med Syst 2014;38(4):1-11
   PubMed Web of Science ®Google Scholar
• Figueiredo IN, Kumar S, Leal C, Figueiredo PN. Computer-assisted bleeding detection in wireless capsule endoscopy images. Comput Methods Biomech Biomed Engin 2013;1(4):198-210
   Google Scholar
• Pan GB, Xu F, Chen JL. Bleeding detection in wireless capsule endoscopy using color similarity coefficient. Appl Mech Mater 2012;195:307-12
   Google Scholar
• Charisis VS, Hadjileontiadis LJ, Liatsos CN, et al. Capsule endoscopy image analysis using texture information from various color models. Comput Methods Programs Biomed 2012;107(1):61-74
   PubMed Web of Science ®Google Scholar
• Kumar R, Zhao Q, Seshamani S, et al. Assessment of Crohn’s disease lesions in wireless capsule endoscopy images. IEEE Trans Biomed Eng 2012;59(2):355-62
   PubMed Web of Science ®Google Scholar
• Li B, Meng MH. Tumor recognition in wireless capsule endoscopy images using textural features and SVM-based feature selection. IEEE Trans Inf Technol Biomed 2012;16(3):323-9
   PubMedGoogle Scholar
• Li BP, Meng MQH. Comparison of several texture features for tumor detection in CE images. J Med Syst 2012;36(4):2463-9
   PubMed Web of Science ®Google Scholar
• Li B, Meng MQH, Lau JY. Computer-aided small bowel tumor detection for capsule endoscopy. Artif Intell Med 2011;52(1):11-16
   PubMed Web of Science ®Google Scholar
• Mamonov AV, Figueiredo IN, Figueiredo PN, Tsai YHR. Automated polyp detection in colon capsule endoscopy. IEEE Trans Med Imaging 2014;33(7):1488-502
   PubMed Web of Science ®Google Scholar
• Li B, Meng MQH. Automatic polyp detection for wireless capsule endoscopy images. Expert Syst Appl 2012;39(12):10952-8
   Web of Science ®Google Scholar
• Karargyris A, Bourbakis N. Detection of small bowel polyps and ulcers in wireless capsule endoscopy videos. IEEE Trans Biomed Eng 2011;58(10):2777-86
   PubMed Web of Science ®Google Scholar
• Szczypinski P, Klepaczko A, Strzelecki M. Án intelligent automated recognition system of abnormal structures in WCE images. In: Hybrid artificial intelligent systems. Springer; 2011. p. 140-7
   Google Scholar
• Szczypinski P, Klepaczko A, Pazurek M, Daniel P. Texture and color based image segmentation and pathology detection in capsule endoscopy videos. Comput Methods Programs Biomed 2014;113(1):396-411
   PubMed Web of Science ®Google Scholar
• Chen H, Chen J, Peng Q, et al. Automatic hookworm image detection for wireless capsule endoscopy using hybrid color gradient and contourlet transform. In: Biomedical Engineering and Informatics (BMEI), 2013 6th International Conference on. IEEE; 2013. p. 116-20
   Google Scholar
• Segui S, Drozdzal M, Vilarino F, et al. Categorization and segmentation of intestinal content frames for wireless capsule endoscopy. IEEE Trans Inf Technol Biomed 2012;16(6):1341-52
   PubMedGoogle Scholar
• HajiMaghsoudi O, Talebpour A, Soltanian-Zadeh H, Soleimani HA. Automatic informative tissue’s discriminators in WCE. In: Imaging Systems and Techniques (IST), 2012 IEEE International Conference on. IEEE; 16-17 July 2012. p. 18-23
   Google Scholar
• Iakovidis DK, Tsevas S, Polydorou A. Reduction of capsule endoscopy reading times by unsupervised image mining. Comput Med Imaging Graph 2010;34(6):471-8
   PubMed Web of Science ®Google Scholar
• Koulaouzidis A, Tsevas S, Iakovidis DK. Automatic Detection of ’Suspicious’ Capsule Endoscopy Video Segments. In Proceedings of, British Society of Gastroenterology (BSG), Annual Meeting, Manchester, 2014
   Google Scholar
• Fawcett T. An introduction to roc analysis. Pattern Recogn Lett 2006;27(8):861-74
   Web of Science ®Google Scholar
• Karagozler ME, Cheung E, Kwon J, Sitti M. Miniature endoscopic capsule robot using biomimetic micro-patterned adhesives. First IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics. New York, USA. 2006. p. 105-11
   Google Scholar
• Quirini M, Scapellato S, Valdastri P, et al. An approach to capsular endoscopy with active motion. Conf Proc IEEE Eng Med Biol Soc 2007;2007:2827-30
   Google Scholar
• Valdastri P, Quaglia C, Susilo E, et al. Wireless therapeutic endoscopic capsule: in vivo experiment. Endoscopy 2008;40:979-82
   PubMed Web of Science ®Google Scholar
• Glass P, Cheung E, Sitti M. A legged anchoring mechanism for capsule endoscopes using micropatterned adhesives. IEEE Trans Biomed Eng 2008;55:2759-67
   PubMed Web of Science ®Google Scholar
• Valdastri P, Webster RJ3rd, Quaglia C, et al. A new mechanism for meso-scale legged locomotion in compliant tubular environments. IEEE T Robot 2009;25:1047-57
   Web of Science ®Google Scholar
• Tortora G, Valdastri P, Susilo E, et al. Propeller-based wireless device for active capsular endoscopy in the gastric district. Minim Invasive Ther Allied Technol 2009;18:280-90
   PubMed Web of Science ®Google Scholar
• Valdastri P, Quaglia C, Buselli E, et al. A magnetic internal mechanism for precise orientation of the camera in wireless endoluminal applications. Endoscopy 2010;42:481-6
   PubMed Web of Science ®Google Scholar
• Ciuti G, Valdastri P, Menciassi A, Dario P. Robotic magnetic steering and locomotion of capsule endoscope for diagnostic and surgical endoluminal procedures. Robotica 2010;28:199-207
   Web of Science ®Google Scholar
• Bourbakis N, Giakos G, Karargyris A. Design of new-generation robotic capsules for therapeutic and diagnostic endoscopy. IEEE International Conference on Imaging Systems and Techniques. New York.2010. p. 1-6
   Google Scholar
• Gao M, Hu C, Chen Z, et al. Design and fabrication of a magnetic propulsion system for self-propelled capsule endoscope. IEEE Trans Biomed Eng 2010;57:2891-902
   PubMed Web of Science ®Google Scholar
• Simi M, Valdastri P, Quaglia C, et al. Design, fabrication, and testing of a capsule with hybrid locomotion for gastrointestinal tract exploration. IEEE-ASME T Mech 2010;15:170-80
   Web of Science ®Google Scholar
• Morita E, Ohtsuka N, Shindo Y, et al. In vivo trial of a driving system for a self-propelling capsule endoscope using a magnetic field (with video). Gastrointest Endosc 2010;72:836-40
   PubMed Web of Science ®Google Scholar
• Yang S, Park K, Kim J, et al. Autonomous locomotion of capsule endoscope in gastrointestinal tract. Conf Proc IEEE Eng Med Biol Soc 2011;2011:6659-63
   Google Scholar
• Filip D, Eggermont M, Nagel J, Andrews CN. Electronic Stool (e-Stool): a novel self-stabilizing video capsule endoscope for reliable non-invasive colonic imaging. International Mechanical Engineering Congress and Exposition, Volume 2, Biomedical and Biotechnology Engineering; Nanoengineering for Medicine and Biology In: Proceedings of the ASME; New York. ASME, 2011. 711-22
   Google Scholar
• Yim S, Sitti M. Design and rolling locomotion of a magnetically actuated soft capsule endoscope. IEEE T Robot 2012;28:183-94
   Web of Science ®Google Scholar
• Kong K, Yim S, Choi S, Jeon D. A Robotic biopsy device for capsule endoscopy. J Med Devices 2012;6(3):031004
   Google Scholar
• http://www.research.philips.com/initiatives/intellicap/
   Google Scholar
• Laursen EL, Ersbøll AK, Rasmussen AM, et al. [Intra- and interobserver variation in capsule endoscopy reviews]. Ugeskr Laeger 2009;171:1929-34
   PubMedGoogle Scholar
• Tang TB, Johannessen EA, Wang L, et al. IDEAS: A minatrue lab-in-a-chip pill multisensor microsystem. In: Proceeding IEEE NORCHIP Conference 2002, Copenhagen, Denmark
   Google Scholar