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Contemporary methods for the diagnosis and treatment of microscopic colitis

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References

  • Lindström CG. “Collagenous colitis” with watery diarrhoea–a new entity? Pathol Eur 1976;11(1):87-9
  • Lazenby AJ, Yardley JH, Giardiello FM, et al. Lymphocytic (“microscopic”) colitis: a comparative histopathologic study with particular reference to collagenous colitis. Hum Pathol 1989;20(1):18-28
  • Münch A, Aust D, Bohr J, et al. Microscopic colitis: Current status, present and future challenges: Statements of the european microscopic colitis group. J Crohn’s Colitis 2012;6(9):932-45
  • Olesen M, Eriksson S, Bohr J, et al. Lymphocytic colitis: a retrospective clinical study of 199 Swedish patients. Gut 2004;53(4):536-41
  • Williams JJ, Beck PL, Andrews CN, et al. Microscopic colitis - a common cause of diarrhoea in older adults. Age Ageing 2010;39(2):162-8
  • Bohr J, Tysk C, Eriksson S, et al. Collagenous colitis: a retrospective study of clinical presentation and treatment in 163 patients. Gut 1996;39(6):846-51
  • Tong J, Zheng Q, Zhang C, et al. Incidence, prevalence, and temporal trends of microscopic colitis: a systematic review and meta-analysis. Am J Gastroenterol 2015;110(2):265-76
  • Pardi DS, Loftus EVJr, Smyrk TC, et al. The epidemiology of microscopic colitis: a population based study in Olmsted County, Minnesota. Gut 2007;56(4):504-8
  • Gentile NM, Khanna S, Loftus EVJr, et al. The Epidemiology of Microscopic Colitis in Olmsted County From 2002 to 2010: A Population-Based Study. Clin Gastroenterol Hepatol 2014;12(5):838-42
  • Williams JJ, Kaplan GG, Makhija S, et al. Microscopic colitis-defining incidence rates and risk factors: a population-based study. Clin Gastroenterol Hepatol 2008;6(1):35-40
  • Olesen M, Eriksson S, Bohr J, et al. Microscopic colitis: a common diarrhoeal disease. An epidemiological study in Orebro, Sweden, 1993-1998. Gut 2004;53(3):346-50
  • Wickbom A, Bohr J, Eriksson S, et al. Stable incidence of colitis and lymphocytic colitis in örebro, sweden, 1999-2008: a continuous epidemiologic study. Inflamm Bowel Dis 2013;19(11):2387-93
  • Fernández-Bañares F, Salas A, Forné M, et al. Incidence of collagenous and lymphocytic colitis: A 5-year population- based study. Am J Gastroenterol 1999;94(2):418-23
  • Fernández-Bañares F, Salas A, Esteve M, et al. Evolution of the incidence of collagenous colitis and lymphocytic colitis in Terrassa, Spain: A population-based study. Inflamm Bowel Dis 2011;17(4):1015-20
  • Sonnenberg A, Genta RM. Geographic distributions of microscopic colitis and inflammatory bowel disease in the United States. Inflamm Bowel Dis 2012;18(12):2288-93
  • Verhaegh BP, Jonkers DM, Driessen A, et al. Incidence of microscopic colitis in the Netherlands. A nationwide population-based study from 2000 to 2012. Dig Liver Dis 2015;47(1):30-6
  • Bürgel N, Bojarski C, Mankertz J, et al. Mechanisms of diarrhea in collagenous colitis. Gastroenterology 2002;123(2):433-43
  • Münch A, Söderholm JD, Ost A, Ström M. Increased transmucosal uptake of E. coli K12 in collagenous colitis persists after budesonide treatment. Am J Gastroenterol 2009;104(3):679-85
  • Tagkalidis PP, Gibson PR, Bhathal PS. Microscopic colitis demonstrates a T helper cell type 1 mucosal cytokine profile. J Clin Pathol 2007;60(4):382-7
  • Andresen L, Jørgensen VL, Perner A, et al. Activation of nuclear factor kappaB in colonic mucosa from patients with collagenous and ulcerative colitis. Gut 2005;54(4):503-9
  • Bohr J, Järnerot G, Tysk C, et al. Effect of fasting on diarrhoea in collagenous colitis. Digestion 2002;65(1):30-4
  • Abdo AA, Zetler PJ, Halparin LS. Familial microscopic colitis. Can J Gastroenterol 2001;15(5):341-3
  • Järnerot G, Hertervig E, Grännö C, et al. Familial occurrence of microscopic colitis: a report on five families. Scand J Gastroenterol 2001;36(9):959-62
  • Finne KD, Do K, Schulte K, et al. High prevalence of celiac sprue-like HLA-DQ genes and enteropathy in patients with the microscopic colitis syndrome. Am J Gastroenterol 2000;95(8):1974-82
  • Koskela RM, Karttunen TJ, Niemelä SE, et al. Human leucocyte antigen and TNFalpha polymorphism association in microscopic colitis. Eur J Gastroenterol Hepatol 2008;20(4):276-82
  • Fernández-Bañares F, Esteve M, Farré C, et al. Predisposing HLA-DQ2 and HLA-DQ8 haplotypes of coeliac disease and associated enteropathy in microscopic colitis. Eur J Gastroenterol Hepatol 2005;17(12):1333-8
  • Madisch A, Hellmig S, Schreiber S, et al. Allelic variation of the matrix metalloproteinase-9 gene is associated with collagenous colitis. Inflamm Bowel Dis 2011;17(11):2295-8
  • Pardi DS, Ramnath VR, Loftus EVJr, et al. Lymphocytic colitis: clinical features, treatment, and outcomes. Am J Gastroenterol 2002;97(11):2829-33
  • Vigren L, Tysk C, Strom M, et al. Celiac disease and other autoimmune diseases in patients with collagenous colitis. Scand J Gastroenterol 2013;48(8):944-50
  • Jegadeesan R, Liu X, Pagadala MR, et al. Microscopic colitis: is it a spectrum of inflammatory bowel disease? World J Gastroenterol 2013;19(26):4252-6
  • Thörn M, Sjöberg D, Ekbom A, et al. Microscopic colitis in Uppsala health region, a population-based prospective study 2005–2009. Scand J Gastroenterol 2013;48(7):825-30
  • Macaigne G, Lahmek P, Locher C, et al. Microscopic Colitis or Functional Bowel Disease With Diarrhea: A French Prospective Multicenter Study. Am J Gastroenterol 2014;109(9):1461-70
  • Rönnblom A, Holmström T, Tanghöj H, et al. Celiac disease, collagenous sprue and microscopic colitis in IBD. Observations from a population-based cohort of IBD (ICURE). Scand J Gastroenterol 2015;50(10):1234-40
  • Vigren L, Sjöberg K, Benoni C, et al. Is smoking a risk factor for collagenous colitis? Scand J Gastroenterol 2011;46(11):1334-9
  • Fernandez-Banares F, de Sousa M, Salas A, et al. Impact of Current Smoking on the Clinical Course of Microscopic Colitis. Inflamm Bowel Dis 2013;19(7):1470-6
  • Yen EF, Pokhrel B, Du H, et al. Current and past cigarette smoking significantly increase risk for microscopic colitis. Inflamm Bowel Dis 2012;18(10):1835-41
  • Roth B, Gustafsson RJ, Jeppsson B, et al. Smoking- and alcohol habits in relation to the clinical picture of women with microscopic colitis compared to controls. BMC Womens Health 2014;14:16
  • Bohr J, Tysk C, Eriksson S, et al. Collagenous colitis: a retrospective study of clinical presentation and treatment in 163 patients. Gut 1996;39(6):846-51
  • Mäkinen M, Niemelä S, Lehtola J, Karttunen TJ. Collagenous colitis and Yersinia enterocolitica infection. Dig Dis Sci 1998;43(6):1341-6
  • Perk G, Ackerman Z, Cohen P, Eliakim R. Lymphocytic colitis: a clue to an infectious trigger. Scand J Gastroenterol 1999;34(1):110-12
  • Fernández-Bañares F, Esteve M, Espinós JC, et al. Drug consumption and the risk of microscopic colitis. Am J Gastroenterol 2007;102(2):324-30
  • Keszthelyi D, Jansen SV, Schouten GA, et al. Proton pump inhibitor use is associated with an increased risk for microscopic colitis: a case-control study. Aliment Pharmacol Ther 2010;32(9):1124-8
  • Fernández-Bañares F, De Sousa MR, Salas A, et al. Epidemiological risk factors in microscopic colitis: A prospective case-control study. Inflamm Bowel Dis 2013;19(2):411-17
  • Bonderup OK, Fenger-Grøn M, et al. Drug Exposure and Risk of Microscopic Colitis: A Nationwide Danish Case-Control Study with 5751 Cases. Inflamm Bowel Dis 2014;20:1702-7
  • Masclee GM, Coloma PM, Kuipers EJ, Sturkenboom MC. Increased Risk of Microscopic Colitis With Use of Proton Pump Inhibitors and Non-Steroidal Anti-Infl ammatory Drugs. Am J Gastroenterol 2015;110(5):749-59
  • Fernández-Bañares F, Esteve M, Salas A, et al. Bile acid malabsorption in microscopic colitis and in previously unexplained functional chronic diarrhea. Dig Dis Sci 2001;46(10):2231-8
  • Ung KA, Gillberg R, Kilander A, Abrahamsson H. Role of bile acids and bile acid binding agents in patients with collagenous colitis. Gut 2000;46(2):170-5
  • Ung KA, Kilander A, Willén R, Abrahamsson H. Role of bile acids in lymphocytic colitis. Hepatogastroenterology 2002;49(44):432-7
  • Roth B, Ohlsson B. Gastrointestinal symptoms and psychological well-being in patients with microscopic colitis. Scand J Gastroenterol 2013;48:27-34
  • Hjortswanga H, Tyskb C, Bohrb J, et al. Health-related quality of life is impaired in active collagenous colitis. Dig Liver Dis 2011;43(2):102-9
  • Kao KT, Pedraza BA, McClune AC, et al. Microscopic colitis: a large retrospective analysis from a health maintenance organization experience. World J. Gastroenterol 2009;15(25):3122-7
  • Roth B, Gustafsson RJ, Ohlsson B. Auto-Antibodies and Their Association with Clinical Findings in Women Diagnosed with Microscopic Colitis. PLoS One 2013;8(6):e66088
  • Wildt S, Nordgaard-Lassen I, Bendtsen F, Rumessen JJ. Metabolic and inflammatory faecal markers in collagenous colitis. Eur J Gastroenterol Hepatol 2007;19(7):567-74
  • Miehlke S, Madisch A, Bethke B, et al. Oral Budesonide for Maintenance Treatment of Collagenous Colitis: A Randomized, Double-Blind, Placebo-Controlled Trial. Gastroenterology 2008;135(5):1510-16
  • Bonderup OK, Hansen JB, Teglbjaerg PS, et al. Long-term budesonide treatment of collagenous colitis: a randomised, double-blind, placebo-controlled trial. Gut 2009;58(1):68-72
  • Münch A, Bohr J, Miehlke S, et al. Low-dose budesonide for maintenance of clinical remission in collagenous colitis: a randomised, placebo-controlled, 12-month trial. Gut 2014
  • Chan JL, Tersmette AC, Offerhaus GJ, et al. Cancer risk in collagenous colitis. Inflamm Bowel Dis 1999;5(1):40-3
  • Yen EF, Pokhrel B, Bianchi LK, et al. Decreased colorectal cancer and adenoma risk in patients with microscopic colitis. Dig Dis Sci 2012;57(1):161-9
  • Tontini GE, Pastorelli L, Spina L, et al. Microscopic Colitis and Colorectal Neoplastic Lesion Rate in Chronic Nonbloody Diarrhea: A Prospective, Multicenter Study. Dig Dis Sci 2014;20(5):882-91
  • Sonnenberg A, Genta RM. Low Prevalence of Colon Polyps in Chronic Infl ammatory Conditions of the Colon. Am J Gastroenterol 2015;110(7):1056-61
  • Tanaka M, Mazzoleni G, Riddell RH. Distribution of collagenous colitis: utility of flexible sigmoidoscopy. Gut 1992;33(1):65-70
  • Yantiss RK, Odze RD. Optimal approach to obtaining mucosal biopsies for assessment of inflammatory disorders of the gastrointestinal tract. Am J Gastroenterol 2009;104(3):774-83
  • Langner C, Aust D, Ensari A, et al. Histology of microscopic colitis-review with a practical approach for pathologists. Histopathology 2015;66(5):613-26
  • Magro F, Langner C, Driessen A, et al. European consensus on the histopathology of inflammatory bowel disease. J Crohns Colitis 2013;7(10):827-51
  • Münch A, Langner C. Microscopic Colitis: Clinical and Pathologic Perspectives. Clin Gastroenterol Hepatol 2014;13(2):228-36
  • Goff JS, Barnett JL, Pelke T, Appelman HD. Collagenous colitis: histopathology and clinical course. Am J Gastroenterol 1997;92(1):57-60
  • Van den Oord JJ, Geboes K, Desmet VJ. Collagenous colitis: an abnormal collagen table? Two new cases and review of the literature. Am J Gastroenterol 1982;77(6):377-81
  • Libbrecht L, Croes R, Ectors N, et al. Microscopic colitis with giant cells. Histopathology 2002;40(4):335-8
  • De Petris G, Chen L. Evolution of microscopic colitis to giant cell colitis without significant intraepithelial lymphocytosis or thickened collagen plate. Int J Surg Pathol 2015;23(3):225-9
  • Saurine TJ, Brewer JM, Eckstein RP. Microscopic colitis with granulomatous inflammation. Histopathology 2004;45(1):82-6
  • Fiel MI, Robbins D, Harpaz N. Pseudomembranous variant of collagenous colitis. Mod Pathol 2003;16:118A
  • Geboes K, Riddell R, Jain D. Inflammatory bowel diseases. Gastrointestinal Pathology and its Clinical Implications. 2nd edition. Wolter Kluwer Health, Lippincot Williams & Wilkins; Philadelphia; 2014
  • Goldstein NS, Bhanot P. Paucicellular and asymptomatic lymphocytic colitis: Expanding the clinicopathologic spectrum of lymphocytic colitis. Am J Clin Pathol 2004;122(3):405-11
  • Chande N, MacDonald JK, McDonald JW. Interventions for treating microscopic colitis: a Cochrane Inflammatory Bowel Disease and Functional Bowel Disorders Review Group systematic review of randomized trials. Am J Gastroenterol 2009;104(1):235-41
  • Stewart MJ, Seow CH, Storr MA. Prednisolone and Budesonide for Short- and Long-Term Treatment of Microscopic Colitis: Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol 2011;9(10):881-90
  • Baert F, Schmit A, D’Haens G, et al. Budesonide in collagenous colitis: a double-blind placebo-controlled trial with histologic follow-up. Gastroenterology 2002;122(1):20-5
  • Miehlke S, Heymer P, Bethke B, et al. Budesonide treatment for collagenous colitis: a randomized, double-blind, placebo-controlled, multicenter trial. Gastroenterology 2002;123(4):978-84
  • Bonderup OK, Hansen JB, Birket-Smith L, et al. Budesonide treatment of collagenous colitis: a randomised, double blind, placebo controlled trial with morphometric analysis. Gut 2003;52(2):248-51
  • Miehlke S, Madisch A, Voss C, et al. Long-term follow-up of collagenous colitis after induction of clinical remission with budesonide. Aliment Pharmacol Ther 2005;22(11-12):1115-19
  • Madisch A, Heymer P, Voss C, et al. Oral budesonide therapy improves quality of life in patients with collagenous colitis. Int J Color Dis 2005;20(4):312-16
  • Miehlke S, Madisch A, Kupcinskas L, et al. Budesonide is more effective than mesalamine or placebo in short-term treatment of collagenous colitis. Gastroenterology 2014;146(5):1222-30
  • Miehlke S, Madisch A, Karimi D, et al. Budesonide Is Effective in Treating Lymphocytic Colitis: A Randomized Double-Blind Placebo-Controlled Study. Gastroenterology 2009;136(7):2092-100
  • Jensen L, Munk LK. Elementary diet reduces diarrhoea associated with microscopic colitis. Scand J Gastroenterol 2005;40(12):1495-6
  • Madisch A, Miehlke S, Eichele O, et al. Boswellia serrata extract for the treatment of collagenous colitis. A double-blind, randomized, placebo-controlled, multicenter trial. Int J Colorectal Dis 2007;22(12):1445-51
  • Wildt S, Munck LK, Vinter-Jensen L, et al. Probiotic treatment of collagenous colitis: a randomized, double-blind, placebo-controlled trial with Lactobacillus acidophilus and Bifidobacterium animalis subsp. Lactis. Inflamm Bowel Dis 2006;12(5):395-401
  • Colussi D, Salari B, Stewart KO, et al. Clinical characteristics and patterns and predictors of response to therapy in collagenous and lymphocytic colitis. Scand J Gastroenterol 2015;50(11):1382-8
  • Fernández-Bañares F, Salas A, Esteve M, et al. Collagenous and lymphocytic colitis. evaluation of clinical and histological features, response to treatment, and long-term follow-up. Am J Gastroenterol 2003;98(2):340-7
  • Calabrese C, Fabbri A, Areni A, et al. Mesalazine with or without cholestyramine in the treatment of microscopic colitis: Randomized controlled trial. J Gastroenterol. Hepatol 2007;22(6):809-14
  • Fine KD, Lee EL. Efficacy of open-label bismuth subsalicylate for the treatment of microscopic colitis. Gastroenterology 1998;114(1):29-36
  • Pardi DS, Loftus EVJr, Tremaine WJ, Sandborn WJ. Treatment of refractory microscopic colitis with azathioprine and 6-mercaptopurine. Gastroenterology 2001;120(6):1483-4
  • Munch A, Fernandez-Banares F, Munck LK. Azathioprine and mercaptopurine in the management of patients with chronic, active microscopic colitis. Aliment Pharmacol Ther 2013;37(8):795-8
  • Vennamaneni SR, Bonner GF. Use of azathioprine or 6-mercaptopurine for treatment of steroid-dependent lymphocytic and collagenous colitis. Am J Gastroenterol 2001;96(9):2798-9
  • Münch A, Bohr J, Vigren L, et al. Lack of effect of methotrexate in budesonide-refractory collagenous colitis. Clin Exp Gastroenterol 2013;6(1):149-52
  • Riddell J, Hillman L, Chiragakis L, Clarke A. Collagenous colitis: Oral low-dose methotrexate for patients with difficult symptoms: Long-term outcomes. J Gastroenterol Hepatol 2007;22(10):1589-93
  • Esteve M, Mahadevan U, Sainz E, et al. Efficacy of anti-TNF therapies in refractory severe microscopic colitis. J Crohn’s Colitis 2011;5(6):612-18
  • Münch A, Ignatova S, Ström M. Adalimumab in budesonide and methotrexate refractory collagenous colitis. Scand J Gastroenterol 2012;47(1):59-63
  • Järnerot G, Tysk C, Bohr J, Eriksson S. Collagenous colitis and fecal stream diversion. Gastroenterology 1995;109(2):449-55
  • Fischer H, Holst E, Karlsson F, et al. Altered microbiota in microscopic colitis. Gut 2015;64(7):1185-6
  • Everard A, Belzer C, Geurts L, et al. Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity. Proc Natl Acad Sci USA 2013;110(22):9066-71
  • Gentile NM, Abdalla AA, Khanna S, et al. Outcomes of patients with microscopic colitis treated with corticoisteroids: a population-based study. Am J Gastroenterol 2012;108(2):256-259

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