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Expert Review of Gastroenterology & Hepatology Volume 10, 2016 - Issue 1
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Reviews

Latest advances in the pathological understanding of cholangiocarcinomas

Yasuni NakanumaDepartment of Diagnostic Pathology, Shizuoka Cancer Center, Shizuoka, JapanCorrespondence[email protected]
,
Takashi MiyataDepartment of Diagnostic Pathology, Shizuoka Cancer Center, Shizuoka, Japan;Department of Hepatobiliary Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, Japan
&
Tsuneyuki UchidaDepartment of Diagnostic Pathology, Shizuoka Cancer Center, Shizuoka, Japan;Department of Hepatobiliary Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, Japan
Pages 113-127 | Published online: 22 Oct 2015

References

  • Papers of special note have been highlighted as:
  • * of interest
  • ** of considerable interest
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*Firstly described CCA resembling reactive bile ducts and referred this subtype to hepatic progenitor cells.

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**First showed the presence of biliary tract stem cells in the peribiliary glands and their differentiation to pancreatic tissue and cholangiocytes.

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*First described a majority of biliary cystic neoplasm belong to intraductal papillary neoplasm of bile.

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*First described the neoplastic lesions in the peribiliary glands and the relation of these lesions with pancreatic branch type IPMN.

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*This is the first study describing ductal plate malformation structures in cholangiocarcinoma.

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**Consensus report on the grade of biliary intraepithelial neoplasia and on practical algorism for the diagnosis.

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*This is the first study of intraductal papillary neoplasm of bile duct showing similarity to pancreatic intraductal papillary mucinous neoplasm.

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**First review on the role and spectrum of the peribiliary glands in a variety of human biliary tract disease.

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