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The role of insulin resistance in nonalcoholic steatohepatitis and liver disease development – a potential therapeutic target?

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Pages 229-242 | Received 28 Aug 2015, Accepted 15 Oct 2015, Published online: 05 Dec 2015

References

  • Papers of special note have been highlighted as:
  • * of interest
  • ** of considerable interest
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  • ** Important paper which describe the interaction between IR and NAFLD
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* Important review about NAFLD.

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* Important paper about the role of Foxo activation during NAFLD which leads to deregulation of gluconeogenesis and persistent hepatic glucose output.

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* Important paper which describe the correlation between Notch signaling and insulin resistance in NAFLD.

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* Important paper about the role of genetic variants in the NAFLD pathogenesis and liver disease progression.

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* Important paper about the role of IR in NAFLD progression.

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* Important paper about genetic variants which have been associated with the severity of liver damage.

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* Important paper which describe an association between IR and fibrogenesis in NASH and HCV.

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