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Editorial

Aging and the microbiome: implications for asthma in the elderly?

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References

  • Chotirmall SH, Watts M, Branagan P, et al. Diagnosis and management of asthma in older adults. J Am Geriatr Soc 2009;57(5):901-9
  • Al-Alawi M, Hassan T, Chotirmall SH. Advances in the diagnosis and management of asthma in older adults. Am J Med 2014;127(5):370-8
  • Human Microbiome Project C. Structure, function and diversity of the healthy human microbiome. Nature 2012;486(7402):207-14
  • Fulop T, Le Page A, Fortin C, et al. Cellular signaling in the aging immune system. Curr Opin Immunol 2014;29C:105-11
  • Castelo-Branco C, Soveral I. The immune system and aging: a review. Gynecol Endocrinol 2014;30(1):16-22
  • Franceschi C, Bonafe M, Valensin S, et al. Inflamm-aging. An evolutionary perspective on immunosenescence. Ann N Y Acad Sci 2000;908:244-54
  • De Martinis M, Franceschi C, Monti D, et al. Inflamm-ageing and lifelong antigenic load as major determinants of ageing rate and longevity. FEBS Lett 2005;579(10):2035-9
  • Heintz C, Mair W. You are what you host: microbiome modulation of the aging process. Cell 2014;156(3):408-11
  • Human Microbiome Project C. A framework for human microbiome research. Nature 2012;486(7402):215-21
  • Cox MJ, Cookson WO, Moffatt MF. Sequencing the human microbiome in health and disease. Hum Mol Genet 2013;22(R1):R88-94
  • Atarashi K, Tanoue T, Oshima K, et al. Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota. Nature 2013;500(7461):232-6
  • Han MK, Huang YJ, Lipuma JJ, et al. Significance of the microbiome in obstructive lung disease. Thorax 2012;67(5):456-63
  • Hilty M, Burke C, Pedro H, et al. Disordered microbial communities in asthmatic airways. PloS One 2010;5(1):e8578
  • Huang YJ, Nelson CE, Brodie EL, et al. Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma. J Allergy Clin Immunol 2011;127(2):372-81
  • Marri PR, Stern DA, Wright AL, et al. Asthma-associated differences in microbial composition of induced sputum. J Allergy Clin Immunol 2013;131(2):346-52
  • Goleva E, Jackson LP, Harris JK, et al. The effects of airway microbiome on corticosteroid responsiveness in asthma. Am J Respir Crit Care Med 2013;188(10):1193-201
  • Huang YJ, Nariya S, Lynch SV, et al. The Airway Microbiome in Severe Asthma. Ann Am Thorac Soc 2014;11(Suppl 1):S78
  • van Woerden HC, Gregory C, Brown R, et al. Differences in fungi present in induced sputum samples from asthma patients and non-atopic controls: a community based case control study. BMC Infect Dis 2013;13:69
  • Fischer GJ AK, Berthier E, Keller NP. Fungal lipoxygenases: a novel instigator of asthma? In: 27th Fungal Genentics Conference. Asilomar Conference Center; 12-17 March 2013; Pacific Grove, CA
  • Chotirmall SH, Al-Alawi M, Mirkovic B, et al. Aspergillus-associated airway disease, inflammation, and the innate immune response. Biomed Res Int 2013;2013:723129
  • Zhang R, Hou A. Host-Microbe Interactions in Caenorhabditis elegans. ISRN Microbiol 2013;2013:356451
  • Gollwitzer ES, Saglani S, Trompette A, et al. Lung microbiota promotes tolerance to allergens in neonates via PD-L1. Nat Med 2014;20(6):642-7
  • Trompette A, Gollwitzer ES, Yadava K, et al. Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis. Nat Med 2014;20(2):159-66
  • Claesson MJ, Jeffery IB, Conde S, et al. Gut microbiota composition correlates with diet and health in the elderly. Nature 2012;488(7410):178-84

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