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Expert Review of Clinical Pharmacology Volume 9, 2016 - Issue 3
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Editorials

What is needed to incorporate clinical pharmacogenetic tests into the practice of psychopharmacotherapy?

Jose de LeonUniversity of Kentucky Mental Health Research Center, Eastern State Hospital, Lexington, KY, USA;Psychiatry and Neurosciences Research Group (CTS-549), Institute of Neurosciences, University of Granada, Granada, Spain;Biomedical Research Centre in Mental Health Net (CIBERSAM), Santiago Apóstol Hospital, University of the Basque Country, Vitoria, SpainCorrespondence[email protected]
&
Edoardo SpinaDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy
Pages 351-354 | Published online: 18 Nov 2015

References

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  • Chou WH, Yan FX, de Leon J, et al. Extension of a pilot study: impact from the cytochrome P450 2D6 polymorphism on outcome and costs associated with severe mental illness. J Clin Psychopharmacol. 2000;20(2):246–251.
  • de Leon J. Translating pharmacogenetics to clinical practice: do cytochrome P450 2D6 ultrarapid metabolizers need higher atomoxetine doses? J Am Acad Child Adolesc Psychiatry. 2015;54(7):532–534.
  • Chung WH, Hung SI, Hong HS, et al. Medical genetics: a marker for Stevens-Johnson syndrome. Nature. 2004;428(6982):486.
  • Chen P, Lin JJ, Lu CS, et al. Carbamazepine-induced toxic effects and HLA-B*1502 screening in Taiwan. N Engl J Med. 2011;364(12):1126–1133.
  • Fibiger HC. Psychiatry, the pharmaceutical industry, and the road to better therapeutics. Schizophr Bull. 2012;38(4):649–650.

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