References
- Dolcetti L Peranzoni E Ugel S et al. Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF. Eur. J. Immunol. 40(1), 22–35 (2010).
- Nagaraj S Youn JI Weber H et al. Anti-inflammatory triterpenoid blocks immune suppressive function of MDSCs and improves immune response in cancer. Clin. Cancer Res. 16(6), 1812–1823 (2010).
- Nagaraj S Schrum AG Cho HI Celis E Gabrilovich DI. Mechanism of T-cell tolerance induced by myeloid-derived suppressor cells. J. Immunol. 184(6), 3106–3116 (2010).
- Nagaraj S Gabrilovich DI. Myeloid-derived suppressor cells in human cancer. Cancer J. 16(4), 348–353 (2010).
- Herber DL Cao W Nefedova Y et al. Lipid accumulation and dendritic cell dysfunction in cancer. Nat. Med. 16(8), 880–886 (2010).
- Ostrand-Rosenberg S. Myeloid-derived suppressor cells: more mechanisms for inhibiting anti-tumor immunity. Cancer Immunol. Immunother. 59(10), 1593–1600 (2010).
- Nagaraj S Gupta K Pisarev V et al. Altered recognition of antigen is a mechanism of CD8+ T-cell tolerance in cancer. Nat. Med. 13(7), 828–835 (2007).
- Almand B Clark JI Nikitina E et al. Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer. J. Immunol. 166(1), 678–689 (2001).
- Gabrilovich DI Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system. Nat. Rev. Immunol. 9(3), 162–174 (2009).
- Kodumudi KN Woan K Gilvary DL Sahakian E Wei S Djeu JY. A novel chemoimmunomodulating property of docetaxel: suppression of myeloid-derived suppressor cells in tumor bearers. Clin. Cancer Res. 16(18), 4583–4594 (2010).
- Solito S Bronte V Mandruzzato S. Antigen specificity of immune suppression by myeloid-derived suppressor cells. J. Leukoc. Biol. 90(1), 31–36 (2011).
- Chalmin F Ladoire S Mignot G et al. Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells. J. Clin. Invest. 120(2), 457–471 (2010).
- Kodumudi KN Woan K Gilvary DL Sahakian E Wei S Djeu JY. A novel chemoimmunomodulating property of docetaxel: suppression of myeloid-derived suppressor cells in tumor bearers. Clin. Cancer Res. 16(18), 4583–4594 (2010).
- Sinha P Clements VK Ostrand-Rosenberg S. Reduction of myeloid-derived suppressor cells and induction of M1 macrophages facilitate the rejection of established metastatic disease. J. Immunol. 174(2), 636–645 (2005).
- Kusmartsev S Nefedova Y Yoder D Gabrilovich DI. Antigen-specific inhibition of CD8+ T-cell response by immature myeloid cells in cancer is mediated by reactive oxygen species. J. Immunol. 172(2), 989–999 (2004).
- Kusmartsev S Nagaraj S Gabrilovich DI. Tumor-associated CD8+ T-cell tolerance induced by bone marrow-derived immature myeloid cells. J. Immunol. 175(7), 4583–4592 (2005).
- Serafini P Mgebroff S Noonan K Borrello I. Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells. Cancer Res. 68(13), 5439–5449 (2008).
- Nagaraj S Nelson A Youn J Cheng P Quiceno D Gabrilovich D. Antigen-specific CD4+ T-cells regulate function of myeloid-derived suppressor cells in cancer via retrograde MHC class II signaling. Cancer Res. 72(4), 928–938 (2012).
- Kortylewski M Kujawski M Wang T et al. Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent anti-tumor immunity. Nat. Med. 11(12), 1314–1321 (2005).
- Ko JS Zea AH Rini BI et al. Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients. Clin. Cancer Res. 15(6), 2148–2157 (2009).