Diagnostic implications of loss of 5-hydroxymethylcytosine for melanoma

References

• Balch CM, Gershenwald JE, Soong SJ et al. Final version of 2009 AJCC melanoma staging and classification. J. Clin. Oncol. 27(36), 6199–6206 (2009).
   PubMed Web of Science ®Google Scholar
• Tas F. Metastatic behavior in melanoma: timing, pattern, survival, and influencing factors. J. Oncol. doi:10.1155/2012/647684 (2012) (Epub ahead of print).
   PubMedGoogle Scholar
• Nijenhuis CM, Haanen JB, Schellens JH, Beijnen JH. Is combination therapy the next step to overcome resistance and reduce toxicities in melanoma? Cancer Treat. Rev. doi:10.1016/j.ctrv.2012.10.006 (2012) (Epub ahead of print).
   PubMed Web of Science ®Google Scholar
• Ito S, D’Alessio AC, Taranova OV, Hong K, Sowers LC, Zhang Y. Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 466(7310), 1129–1133 (2010).
   PubMed Web of Science ®Google Scholar
• Tahiliani M, Koh KP, Shen Y et al. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 324(5929), 930–935 (2009).
   PubMed Web of Science ®Google Scholar
• Szwagierczak A, Bultmann S, Schmidt CS, Spada F, Leonhardt H. Sensitive enzymatic quantification of 5-hydroxymethylcytosine in genomic DNA. Nucleic Acids Res. 38(19), e181 (2010).
   PubMed Web of Science ®Google Scholar
• Hoon DS, Spugnardi M, Kuo C, Huang SK, Morton DL, Taback B. Profiling epigenetic inactivation of tumor suppressor genes in tumors and plasma from cutaneous melanoma patients. Oncogene 23(22), 4014–4022 (2004).
   PubMed Web of Science ®Google Scholar
• Liu S, Ren S, Howell P, Fodstad O, Riker AI. Identification of novel epigenetically modified genes in human melanoma via promoter methylation gene profiling. Pigment Cell Melanoma Res. 21(5), 545–558 (2008).
   PubMed Web of Science ®Google Scholar
• Shen L, Kondo Y, Guo Y et al. Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters. PLoS Genet. 3(10), 2023–2036 (2007).
   PubMed Web of Science ®Google Scholar
• Paz MF, Fraga MF, Avila S et al. A systematic profile of DNA methylation in human cancer cell lines. Cancer Res. 63(5), 1114–1121 (2003).
   PubMed Web of Science ®Google Scholar
• Conway K, Edmiston SN, Khondker ZS et al. DNA-methylation profiling distinguishes malignant melanomas from benign nevi. Pigment Cell Melanoma Res. 24(2), 352–360 (2011).
   PubMed Web of Science ®Google Scholar
• Tellez CS, Shen L, Estécio MR, Jelinek J, Gershenwald JE, Issa JP. CpG island methylation profiling in human melanoma cell lines. Melanoma Res. 19(3), 146–155 (2009).
   PubMed Web of Science ®Google Scholar
• Lian CG, Xu Y, Ceol C et al. Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma. Cell 150(6), 1135–1146 (2012).
   PubMed Web of Science ®Google Scholar
• Hill LL, Korngold R, Jaworsky C, Murphy G, McCue P, Berd D. Growth and metastasis of fresh human melanoma tissue in mice with severe combined immunodeficiency. Cancer Res. 51(18), 4937–4941 (1991).
   PubMed Web of Science ®Google Scholar
• Juhasz I, Albelda SM, Elder DE et al. Growth and invasion of human melanomas in human skin grafted to immunodeficient mice. Am. J. Pathol. 143(2), 528–537 (1993).
   PubMed Web of Science ®Google Scholar
• Quintana E, Piskounova E, Shackleton M et al. Human melanoma metastasis in NSG mice correlates with clinical outcome in patients. Sci. Transl. Med. 4(159), 159ra149 (2012).
   PubMed Web of Science ®Google Scholar
• Girouard SD, Murphy GF. Melanoma stem cells: not rare, but well done. Lab. Invest. 91(5), 647–664 (2011).
   PubMed Web of Science ®Google Scholar
• Quintana E, Shackleton M, Sabel MS, Fullen DR, Johnson TM, Morrison SJ. Efficient tumour formation by single human melanoma cells. Nature 456(7222), 593–598 (2008).
   PubMed Web of Science ®Google Scholar
• Shakhova O, Sommer L. Testing the cancer stem cell hypothesis in melanoma: The clinics will tell. Cancer Lett. doi:10.1016/j.canlet.2012.10.009 (2012) (Epub ahead of print).
   PubMed Web of Science ®Google Scholar
• Cobb J, Büsst C, Petrou S, Harrap S, Ellis J. Searching for functional genetic variants in non-coding DNA. Clin. Exp. Pharmacol. Physiol. 35(4), 372–375 (2008).
   PubMed Web of Science ®Google Scholar