87
Views
2
CrossRef citations to date
0
Altmetric
Review

Joint involvement in inflammatory bowel disease: managing inflammation outside the digestive system

Pages 81-89 | Published online: 10 Jan 2014

References

  • Orchard TR, Wordsworth BP, Jewell DP. Peripheral arthropathies in inflammatory bowel disease: their articular distribution and natural history. Gut42, 387–381 (1998).
  • Braun J, Sieper J, Bollow M. Imaging of sacroiliitis. Clin. Rheumatol.19, 51–57 (2000).
  • Rudwaleit M, van der Heijde D, Landewé R et al. The development of Assessment of SpondyloArthritis International Society classification criteria for axial spondyloarthritis (part II): validation and final selection. Ann. Rheum. Dis.68, 777–783 (2009).
  • Palm O, Bernklev T, Moum B, Gran JT. Non-inflammatory joint pain in patients with inflammatory bowel disease is prevalent and has a significant impact on health related quality of life. J. Rheumatol.32, 1755–1759 (2005).
  • De Vos M, Cuvelier C, Mielants H, Veys E, Barbier F, Elewaut A. Ileocolonoscopy in seronegative spondylarthropathy. Gastroenterology96, 339–344 (1989).
  • De Vos M, Mielants H, Cuvelier C, Elewaut A, Veys E. Long-term evolution of gut inflammation in patients with spondylarthropathy. Gastroenterology110, 1696–1703 (1996).
  • Demetter P, Van Huysse JA, De Keyser F et al. Increase in lymphoid follicles and leukocyte adhesion molecules emphasizes a role for the gut in spondyloarthropathy pathogenesis. J. Pathol.198, 517–522 (2002).
  • D’Inca R, Podswiadek M, Ferronato A et al. Articular manifestations in inflammatory bowel disease patients: a prospective study. Dig. Liver Dis.41, 565–569 (2009).
  • De Vlam K, Mielants H, Cuvelier C et al. Spondyloarthropathy is underestimated in inflammatory bowel disease: prevalence and HLA association. J. Rheumatol.27, 2860–2865 (2000).
  • Peeters H, Vander Cruyssen B, Mielants H et al. Clinical and genetic factors associated with sacroilliitis in Crohn’s disease. J. Gastroenterol. Hepatol.23, 132–137 (2008).
  • Scott WW Jr, Fishman EK, Kuhlman JE et al. Computed tomography evaluation of the sacroiliac joints in Crohn disease. Radiologic/clinical correlation. Skeletal Radiol.19, 207–210 (1990).
  • McEniff N, Eustace S, McCarthy C et al. Asymptomatic sacroiliitis in inflammatory bowel disease. Assessment by computed tomography. Clin. Imaging19, 258–262 (1995).
  • Salvarani C, Fries W. Clinical futures and epidemiology of spondyloarthritides associated with inflammatory bowel disease. World J. Gastroenterol.15, 2449–2455 (2009).
  • van der Linden SM, Valkenburgh HA, de Jongh BM, Cats A. The risk of developing ankylosing spondylitis in HLAB27 positive individuals. A comparison of relatives of spondylitis patients with general population. Arthr. Rheum.27, 241–249 (1984).
  • Saraux A, Guillemin F, Guggenpuhl P et al. Prevalence of spondyloarthropathy in France: 2001. Ann. Rheum. Dis.64, 1431–1435 (2005).
  • Braun J, Bollow M, Remlinger G et al. Prevalence of spondyloarthropathies in HLA-B27 positive and negative blood donors. Arthritis Rheum.41, 58–67 (1998).
  • Baeten D, De Keyser F. The histopathology of spondyloarthropathy (review). Curr. Mol. Med.4, 1–12 (2004).
  • Elewaut D, van Damme N, Baeten D et al. Enrichment of T cells carrying b7 integrins in inflamed synovial tissue from patients with early spondyloarthropathy compared to rheumatoid arthritis. J. Rheumatol.25, 1932–1937 (1998).
  • Baeten D, Demetter P, Cuvelier CA et al. Macrophages expressing the scavenger receptor CD163: a link between immune alterations of the gut and synovial inflammation in spondyloarthropathy. J. Pathol.196, 343–350 (2002).
  • Demetter P, De Vos M, Van Huysse JA et al. Colon mucosa of patients both with spondyloarthritis and Crohn’s disease is enriched with macrophages expressing the scavenger receptor CD163. Ann. Rheum. Dis.64, 321–324 (2005).
  • Jacques P, Mielants H, Coppieters K, De Vos M, Elewaut D. The intimate relationship between gut and joint in spondyloarthropathies (review). Curr. Opin. Rheumatol.19, 353–357 (2007).
  • Hindryckx P, Serry G, Laukens D, Peeters H, De Vos M. Increased intestinal VEGF expression and mucosal vascularization in patients with spondylarthropathy. Gastroenterology136, A-559 (2009).
  • Polzer K, Baeten D, Soleiman A et al. Tumour necrosis factor blockade increases lymphangiogenesis in murine and human arthritis joints. Ann. Rheum. Dis.67, 1610–1616 (2008).
  • Schett G. Joint remodelling in inflammatory diseases. Ann. Rheum. Dis.66(Suppl. 3), iii42–iii44 (2007).
  • Kontoyiannis D, Pasparakis M, Pizarro TT, Cominelli F, Kollias G. Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: implications for joint and gut-associated immunopathologies. Immunity10, 387–398 (1999).
  • Armaka M, Apostolaki M, Jacques P, Kontoyiannis DL, Elewaut D, Kollias G. Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases. J. Exp. Med.205, 331–337 (2008).
  • Kontoyiannis D, Boulougouris G, Manoloukos M et al. Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn’s-like inflammatory bowel disease. J. Exp. Med.196, 1563–1574 (2002).
  • Taurog JD, Maika SD, Simmons WA, Breban M, Hammer RE. Susceptibility to inflammatory disease in HLA-B27 transgenic rat lines correlates with the level of B27 expression. J. Immunol.150, 4168–4178 (1993).
  • Rath HC, Wilson KH, Sartor RB. Differential induction of colitis and gastritis in HLA B27 transgene rats selectively colonized with Bacteroides vulgatus and Eschericia coli. Infect. Immunol.67, 2969–2974 (1999).
  • Rath HC, Schultz M, Freitag R et al. Different subsets of enteric bacteria induce and perpetuate experimental colitis in rats and mice. Infect. Immun.69, 2277–2285 (2001).
  • Hacquard-Bouder C, Falgarone G, Bosquet A et al. Alteration of antigen-independent immunologic synapse formation between dendritic cells from HLA-B27 transgenic rats and CD4+ T cells: selective impairment of costimulatory molecules engagement by mature HLA-B27. Arthritis Rheum.56, 1478–1489 (2007).
  • Fert I, Glatigny S, Poulain C et al. Correlation between dendritic cell functional defect and spondylarthritis phenotypes in HLA-B27/HUMAN β2-microglobulin-transgenic rat lines. Arthritis Rheum.58, 3425–3429 (2008).
  • Turner MJ, Delay ML, Bai S, Klenk E, Colbert RA. HLA-B27 up-regulation causes accumulation of misfolded heavy chains and correlates with the magnitude of the unfolded protein response in transgenic rats: implications for the pathogenesis of spondylarthritis-like disease. Arthritis Rheum.56, 215–223 (2007).
  • Tran TM, Dorris ML, Satumtira N et al. Additional human β2-microglobulin curbs HLA-B27 misfolding and promotes arthritis and spondylitis without colitis in male HLA-B27 -transgenic rats. Arthritis Rheum.54, 1317–1327 (2006).
  • Reveille JD. Recent studies on the genetic basis of ankylosing spondylitis (review). Curr. Rheumatol. Rep.11, 340–348 (2009).
  • Barrett JC, Hansoul S, Nicolae DL et al. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn’s disease. Nat. Genet.29, 175 (2008).
  • Manel N, Unutmaz D, Littman DR. The differentiation of human Th17 cells require transforming growth factor-β and induction of the nuclear receptor RORg. Nat. Immunol.9, 641–649 (2008).
  • Yang L, Anderson DE, Baecher-Allan C et al. IL-21 and TGF-β are required for differentiation of human Th17 cells. Nature454, 350–352 (2008).
  • Brand S. Crohn’s disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn’s disease. Gut58, 1152–1167 (2009).
  • Schmechel S, Konrad A, Diegelman J et al. Linking genetic susceptibility to Crohn’s disease with Th17 cell function: IL-22 serum levels are increased in Crohn’s disease and correlate with disease activity and IL23R genotype status. Inflamm. Bowel Dis.14, 204–212 (2008).
  • Ciccia F, Bombardieri M, Principato A et al. Overexpression of interleukin-23, but not interleukin-17, as an immunologic signature of subclinical intestinal inflammation in ankylosing spondylitis. Arthritis Rheum.60, 955–965 (2009).
  • Melis L, Vandooren B, Kruithof E et al. Systemic levels of IL-23 are strongly associated with disease activity in rheumatoid arthritis but not spondyloarthritis. Ann. Rheum. Dis. DOI: 10.1136/ard.2009.107649 (2009) (Epub ahead of print).
  • Laukens D, Peeters H, Marichal D et al.CARD15 gene polymorphisms in patients with spondyloarthorpathies identify a specific phenotype previously related to Crohn’s disease. Ann. Rheum. Dis.64, 930–935 (2005).
  • Micelli-Richard C, Zouali H, Lesage S et al. CARD15/NOD2 analyses in spondyloarthropathy. Arthritis Rheum.46, 1405–1406 (2002).
  • Craene AM, Bradbury L, Van Heel DA et al. Role of NOD2 variants in spondyloarthritis. Arthritis Rheum.46, 1629–1633 (2002).
  • Laukens D, Peeters H, Cruyssen BV et al. Altered gut transcriptome in spondyloarthropathy. Ann. Rheum. Dis.65, 1293–1300 (2006).
  • Georges M, Laukens D, Libioulle C et al. Evidence for significant overlap between common risk variants for Crohn’s disease and ankylosing spondylitis. Acta Gastroenterol. Belg.72, 103 (2009).
  • Forrest K, Symmons D, Foster P. Systematic review: is ingestion of paracetamol or non-steroidal antiinflammatory drugs associated with exacerbations of inflammatory bowel disease ? Aliment Pharmacol. Ther.20, 1035–1043 (2004).
  • Feagins LA, Cryer BL. Do non-steroidal anti-inflammatory drugs cause exacerbations of inflammatory bowel disease? Dig. Dis. Sci.55(2), 226–232 (2009).
  • Kefalakes H, Stylianedes TJ, Amanakis G, Kolios G. Exacerbation of inflammatory bowel disease associated with the use of nonsteroidal antiinflammatory drugs: myth or reality? Eur. J. Clin. Pharmacol.65, 963–970 (2009).
  • Singh S, Graff LA, Bernstein CN. Do NSAIDs, antibiotics, infections or stress trigger flares in IBD? Am. J. Gastroenterol.104, 1298–1313 (2009).
  • Felder JB, Korelitz BI, Rajapakse R, Schwarz S, Horatagis AP, Gleim G. Effects of nonsteroidal antiinflammatory drugs on inflammatory bowel disease: a case–control study. Am. J. Gastroenterol.95, 1949–1954 (2000).
  • Takeuchi K, Smale S, Premchand P et al. Prevalence and mechanism of non-steroidal antiinflammatory drug induced clinical relapse in patients with IBD. Clin. Gastroenterol. Hepatol.4, 196–202 (2006).
  • Bonner GF, Fakhri A, Vennamanen SR. A long-term cohort study of non-steroidal antiinflammatory drug use and disease activity in outpatients with inflammatory bowel diseases. Inflamm. Bowel Dis.10, 751–757 (2004).
  • Sandborn WJ, Stenson WF, Brynskov J et al. Safety of celecoxib in patients with ulcerative colitis in remission: a randomised placebo controlled pilot study. Clin. Gastroenterol. Hepatol.4, 203–211 (2006).
  • El Miedany Y, Youssef S, Ahmed I, El Gaafary M. The gastrointestinal safety and effect on disease activity of etoricoxib, a selective COX-2 inhibitor in inflammatory bowel diseases. Am. J. Gastroenterol.101, 311–317 (2006).
  • Zochling J, van der Heijde D, Dougados M, Braun J. Current evidence for the management of ankylosing spondylitis: a systematic literature review for the ASAS/EULAR management recommendations in ankylosing spondylitis. Ann. Rheum. Dis.65, 423–432 (2006).
  • Van den Bosch F, Kruithof E, De Vos M, De Keyser F, Mielants H. Crohn’s disease associated with spondyloarthropathy: effect of TNF-α blockade with infliximab on articular symptoms. Lancet356, 1821–1822 (2000).
  • Generini S, Giacomelli R, Fedi R et al. Infliximab in spondyloarthropathy associated with Crohn’s disease: an open study on the efficacy of inducing and maintaining remission at musculoskeletal and gut manifestations. Ann. Rheum. Dis.63, 1664–1669 (2004).
  • Braun J, Baraliakos X, Listing J et al. Differences in the incidence of flares or new onset of inflammatory bowel disease in patients with ankylosing spondylitis exposed to therapy with anti-TNF agents. Arthritis Rheum.57, 639–647 (2007).
  • Hindryckx P, Waeytens A, Laukens D, Peeters H, Van Huysse J, De Vos M. Absence of placental growth factor aggravates DSS-induced acute colonic injury. J. Crohns Colitis3(1), S124–S125 (2009).
  • Hindryckx P, Laukens D, Jacques P, Peeters H, Vandenabeele P, De Vos M. Protective effect of prolyl hydroxylase inhibition on tumor necrosis factor – induced intestinal pathology. Presented at: GASTRO 2009 UEGW/WCOG. London, UK, 21–25 November 2009.
  • Mannon PJ, Fuss IJ, Mayer L et al. Anti-interleukin 12 antibody for active Crohn’s disease. N. Engl. J. Med.351, 2069–2079 (2004).
  • Burakoff R, Barish CF, Riff D et al. A Phase 1/2 trial of STA 5326, an oral interleukin 12/23 inhibitor in patients with active moderate to severe Crohn’s disease. Inflamm. Bowel Dis.12, 558–565 (2006).
  • Gottlieb A, Menter A, Mendelsohn A et al. Ustekinumab, a human interleukin 12/23 monoclonal antibody, for psoriatic arthritis: randomised, double-blind, placebo-controlled, crossover trial. Lancet373, 633–640 (2009).
  • Toedter GP, Blank M, Lang Y, Chen D, Sandborn WJ, de Villiers WJ. Relationship of C-reactive protein with clinical response after therapy with ustekinumab in Crohn’s disease. Am. J. Gastroenterol.104, 2768–2773 (2009).
  • Canete JD, Celis R, Hernandez MV, Pablos JL, Sanmarti R. Synovial immunopathological changes associated with successful abatacept therapy in a case of severe refractory psoriatic arthritis. Ann. Rheum. Dis. DOI: 10.1136/ard.2009.113233 (2009).
  • Kaser A, Lee AH, Franke A et al. XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease. Cell134, 743–756 (2008).
  • Kaser A, Blumberg RS. Endoplasmic reticulum stress in the intestinal epithelium and inflammatory bowel disease. Semin. Immunol.21, 156–163 (2009).
  • Todd DJ, Lee AH, Glimcher LA et al. The endoplasmatic reticulum stress response in immunity and autoimmunity (review). Nat. Rev.8, 663–674 (2008).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.