Renin–angiotensin system and hemangioblast development from human embryonic stem cells

References

• Zambidis ET, Soon Park T, Yu W et al. Expression of angiotensin-converting enzyme (CD143) identifies and regulates primitive hemangioblasts derived from human pluripotent stem cells. Blood112, 3601–3614 (2008).
   PubMed Web of Science ®Google Scholar
• Thomson JA, Itskovitz-Eldor J, Shapiro SS et al. Embryonic stem cell lines derived from human blastocysts. Science282, 1145–1147 (1998).
   PubMed Web of Science ®Google Scholar
• Kaufman DS, Lewis RL, Hanson ET et al. Functional endothelial cells derived from rhesus monkey embryonic stem cells. Blood103, 1325–1332 (2004).
   PubMed Web of Science ®Google Scholar
• Mikkola HK, Orkin SH. The journey of developing hematopoietic stem cells. Development133, 3733–3744 (2006).
   PubMed Web of Science ®Google Scholar
• Maximow AA. Relation of blood cells to connective tissues and endothelium. Physiol. Rev.4, 533–563 (1924).
   Google Scholar
• Sabin F. Origin and development of the primitive vessels of the chick and of the pig. Carnegie Inst. Wash. Publ. Contribs Embryol.6, 61–124 (1917).
   Google Scholar
• Murray PDF. The development in vitro of the blood of the early chick embryo. Proc. Royal Soc. Lond. SeriesB111, 497–521 (1932).
   Google Scholar
• Kennedy M, Firpo M, Choi K et al. A common precursor for primitive erythropoiesis and definitive haematopoiesis. Nature386, 488–493 (1997).
   PubMed Web of Science ®Google Scholar
• Choi K, Kennedy M, Kazarov A et al. A common precursor for hematopoietic and endothelial cells. Development125, 725–732 (1998).
   PubMed Web of Science ®Google Scholar
• Yamashita J, Itoh H, Hirashima M et al. Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors. Nature408, 92–96 (2000).
   PubMed Web of Science ®Google Scholar
• Kennedy M, D’Souza SL, Lynch-Kattman M et al. Development of the hemangioblast defines the onset of hematopoiesis in human ES cell differentiation cultures. Blood109, 2679–2687 (2007).
   PubMed Web of Science ®Google Scholar
• Wang L, Li L, Shojaei F et al. Endothelial and hematopoietic cell fate of human embryonic stem cells originates from primitive endothelium with hemangioblastic properties. Immunity21, 31–41 (2004).
   PubMed Web of Science ®Google Scholar
• Fehling HJ, Lacaud G, Kubo A et al. Tracking mesoderm induction and its specification to the hemangioblast during embryonic stem cell differentiation. Development130, 4217–4227 (2003).
   PubMed Web of Science ®Google Scholar
• Ramshaw HS, Haylock D, Swart B et al. Monoclonal antibody BB9 raised against bone marrow stromal cells identifies a cell-surface glycoprotein expressed by primitive human hemopoietic progenitors. Exp. Hematol.29, 981–992 (2001).
   PubMedGoogle Scholar
• Jokubaitis VJ, Sinka L, Driessen R et al. Angiotensin-converting enzyme (CD143) marks hematopoietic stem cells in human embryonic, fetal, and adult hematopoietic tissues. Blood111, 4055–4063 (2008).
   PubMed Web of Science ®Google Scholar
• Sauvageau G, Iscove NN, Humphries RK. In vitro and in vivo expansion of hematopoietic stem cells. Oncogene23, 7223–7232 (2004).
   PubMedGoogle Scholar
• Kaufman DS, Hanson ET, Lewis RL et al. Hematopoietic colony-forming cells derived from human embryonic stem cells. Proc. Natl Acad. Sci USA98, 10716–10721 (2001).
   PubMed Web of Science ®Google Scholar
• Vodyanik MA, Bork JA, Thomson JA et al. Human embryonic stem cell-derived CD34+ cells: efficient production in the coculture with OP9 stromal cells and analysis of lymphohematopoietic potential. Blood105, 617–626 (2005).
   PubMed Web of Science ®Google Scholar
• Zambidis ET, Peault B, Park TS et al. Hematopoietic differentiation of human embryonic stem cells progresses through sequential hematoendothelial, primitive, and definitive stages resembling human yolk sac development. Blood106, 860–870 (2005).
   PubMed Web of Science ®Google Scholar
• Yu J, Vodyanik MA, Smuga-Otto K et al. Induced pluripotent stem cell lines derived from human somatic cells. Science318, 1917–1920 (2007).
   PubMed Web of Science ®Google Scholar
• Takahashi K, Tanabe K, Ohnuki M et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell131, 861–872 (2007).
   PubMed Web of Science ®Google Scholar
• Park IH, Zhao R, West JA et al. Reprogramming of human somatic cells to pluripotency with defined factors. Nature451, 141–146 (2008).
   PubMed Web of Science ®Google Scholar
• Kondo M, Wagers AJ, Manz MG et al. Biology of hematopoietic stem cells and progenitors: implications for clinical application. Annu. Rev. Immunol.21, 759–806 (2003).
   PubMed Web of Science ®Google Scholar
• Cumano A, Ferraz JC, Klaine M et al. Intraembryonic, but not yolk sac hematopoietic precursors, isolated before circulation, provide long-term multilineage reconstitution. Immunity15, 477–485 (2001).
   PubMedGoogle Scholar
• Medvinsky AL, Samoylina NL, Muller AM et al. An early pre-liver intraembryonic source of CFU-S in the developing mouse. Nature364, 64–67 (1993).
   PubMed Web of Science ®Google Scholar
• Gekas C, Dieterlen-Lievre F, Orkin SH et al. The placenta is a niche for hematopoietic stem cells. Dev. Cell8, 365–375 (2005).
   PubMed Web of Science ®Google Scholar
• Zovein AC, Hofmann JJ, Lynch M et al. Fate tracing reveals the endothelial origin of hematopoietic stem cells. Cell Stem Cell3, 625–636 (2008).
   PubMed Web of Science ®Google Scholar
• Keller G. Embryonic stem cell differentiation: emergence of a new era in biology and medicine. Genes Dev.19, 1129–1155 (2005).
   PubMed Web of Science ®Google Scholar
• Lensch MW, Daley GQ. Scientific and clinical opportunities for modeling blood disorders with embryonic stem cells. Blood107, 2605–2612 (2006).
   PubMed Web of Science ®Google Scholar
• Olsen AL, Stachura DL, Weiss MJ. Designer blood: creating hematopoietic lineages from embryonic stem cells. Blood107, 1265–1275 (2006).
   PubMedGoogle Scholar
• Tian X, Woll PS, Morris JK et al. Hematopoietic engraftment of human embryonic stem cell-derived cells is regulated by recipient innate immunity. Stem Cells24, 1370–1380 (2006).
   PubMedGoogle Scholar
• Wang L, Menendez P, Shojaei F et al. Generation of hematopoietic repopulating cells from human embryonic stem cells independent of ectopic HOXB4 expression. J. Exp. Med.201, 1603–1614 (2005).
   PubMed Web of Science ®Google Scholar
• Murry CE, Keller G. Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development. Cell132, 661–680 (2008).
   PubMed Web of Science ®Google Scholar
• Doetschman TC, Eistetter H, Katz M et al. The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium. J. Embryol. Exp. Morphol.87, 27–45 (1985).
   PubMedGoogle Scholar
• Burt RK, Verda L, Kim DA et al. Embryonic stem cells as an alternate marrow donor source: engraftment without graft-versus-host disease. J. Exp. Med.199, 895–904 (2004).
   PubMed Web of Science ®Google Scholar
• Narayan AD, Chase JL, Lewis RL et al. Human embryonic stem cell-derived hematopoietic cells are capable of engrafting primary as well as secondary fetal sheep recipients. Blood107, 2180–2183 (2006).
   PubMed Web of Science ®Google Scholar
• Ledran MH, Krassowska A, Armstrong L et al. Efficient hematopoietic differentiation of human embryonic stem cells on stromal cells derived from hematopoietic niches. Cell Stem Cell3, 85–98 (2008).
   PubMed Web of Science ®Google Scholar
• Kyba M, Perlingeiro RC, Daley GQ. HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors. Cell109, 29–37 (2002).
   PubMed Web of Science ®Google Scholar
• Kyba M, Perlingeiro RC, Hoover RR et al. Enhanced hematopoietic differentiation of embryonic stem cells conditionally expressing Stat5. Proc. Natl Acad. Sci. USA100(Suppl. 1), 11904–11910 (2003).
   PubMedGoogle Scholar
• Perlingeiro RC, Kyba M, Daley GQ. Clonal analysis of differentiating embryonic stem cells reveals a hematopoietic progenitor with primitive erythroid and adult lymphoid–myeloid potential. Development128, 4597–4604 (2001).
   PubMedGoogle Scholar
• Wang Y, Yates F, Naveiras O et al. Embryonic stem cell-derived hematopoietic stem cells. Proc. Natl Acad. Sci. USA102, 19081–19086 (2005).
   PubMed Web of Science ®Google Scholar
• Comte L, Lorgeot V, Volkov L et al. Effects of the angiotensin-converting enzyme inhibitor enalapril on blood haematopoietic progenitors and acetyl-N-Ser-Asp-Lys-Pro concentrations. Eur. J. Clin. Invest.27, 788–790 (1997).
   PubMed Web of Science ®Google Scholar
• Chisi JE, Wdzieczak-Bakala J, Thierry J et al. Captopril inhibits the proliferation of hematopoietic stem and progenitor cells in murine long-term bone marrow cultures. Stem Cells17, 339–344 (1999).
   PubMed Web of Science ®Google Scholar
• Rell K, Koziak K, Jarzyo I et al. Correction of posttransplant erythrocytosis with enalapril. Transplantation57, 1059–1063 (1994).
   PubMedGoogle Scholar
• Nomura S, Sugihara T, Tomiyama T et al. Polycythaemia vera: response to treatment with angiotensin-converting enzyme inhibitor. Eur. J. Haematol.57, 117–119 (1996).
   PubMed Web of Science ®Google Scholar
• Lenfant M, Wdzieczak-Bakala J, Guittet E et al. Inhibitor of hematopoietic pluripotent stem cell proliferation: purification and determination of its structure. Proc. Natl Acad. Sci. USA86, 779–782 (1989).
   PubMed Web of Science ®Google Scholar
• Rousseau A, Michaud A, Chauvet MT et al. The hemoregulatory peptide N-acetyl-Ser-Asp-Lys-Pro is a natural and specific substrate of the N-terminal active site of human angiotensin-converting enzyme. J. Biol. Chem.270, 3656–3661 (1995).
   PubMed Web of Science ®Google Scholar
• Cole J, Ertoy D, Lin H et al. Lack of angiotensin II-facilitated erythropoiesis causes anemia in angiotensin-converting enzyme-deficient mice. J. Clin. Invest.106, 1391–1398 (2000).
   PubMed Web of Science ®Google Scholar
• Savary K, Michaud A, Favier J et al. Role of the renin–angiotensin system in primitive erythropoiesis in the chick embryo. Blood105, 103–110 (2005).
   PubMed Web of Science ®Google Scholar
• Grant MB, May WS, Caballero S et al. Adult hematopoietic stem cells provide functional hemangioblast activity during retinal neovascularization. Nat. Med.8, 607–612 (2002).
   PubMed Web of Science ®Google Scholar
• Bailey AS, Jiang S, Afentoulis M et al. Transplanted adult hematopoietic stems cells differentiate into functional endothelial cells. Blood103, 13–19 (2004).
   PubMed Web of Science ®Google Scholar
• Vodyanik MA, Thomson JA, Slukvin, II. Leukosialin (CD43) defines hematopoietic progenitors in human embryonic stem cell differentiation cultures. Blood108, 2095–2105 (2006).
   PubMedGoogle Scholar
• Qiu C, Hanson E, Olivier E et al. Differentiation of human embryonic stem cells into hematopoietic cells by coculture with human fetal liver cells recapitulates the globin switch that occurs early in development. Exp. Hematol.33, 1450–1458 (2005).
   PubMed Web of Science ®Google Scholar
• Lu SJ, Feng Q, Park JS et al. Biologic properties and enucleation of red blood cells from human embryonic stem cells. Blood112, 4475–4484 (2008).
   PubMed Web of Science ®Google Scholar
• Ma F, Ebihara Y, Umeda K et al. Generation of functional erythrocytes from human embryonic stem cell-derived definitive hematopoiesis. Proc. Natl Acad. Sci. USA105, 13087–13092 (2008).
   PubMedGoogle Scholar
• Gaur M, Kamata T, Wang S et al. Megakaryocytes derived from human embryonic stem cells: a genetically tractable system to study megakaryocytopoiesis and integrin function. J. Thromb. Haemost.4, 436–442 (2006).
   PubMed Web of Science ®Google Scholar
• Takayama N, Nishikii H, Usui J et al. Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors. Blood111, 5298–5306 (2008).
   PubMed Web of Science ®Google Scholar
• Saeki K, Nakahara M, Matsuyama S et al. A feeder-free and efficient production of functional neutrophils from human embryonic stem cells. Stem Cells27(1), 59–67 (2009).
   PubMedGoogle Scholar
• Karlsson KR, Cowley S, Martinez FO et al. Homogeneous monocytes and macrophages from human embryonic stem cells following coculture-free differentiation in M-CSF and IL-3. Exp. Hematol.36, 1167–1175 (2008).
   PubMed Web of Science ®Google Scholar
• Senju S, Hirata S, Matsuyoshi H et al. Generation and genetic modification of dendritic cells derived from mouse embryonic stem cells. Blood101, 3501–3508 (2003).
   PubMed Web of Science ®Google Scholar
• Slukvin II, Vodyanik MA, Thomson JA et al. Directed differentiation of human embryonic stem cells into functional dendritic cells through the myeloid pathway. J. Immunol.176, 2924–2932 (2006).
   PubMedGoogle Scholar
• Woll PS, Martin CH, Miller JS et al. Human embryonic stem cell-derived NK cells acquire functional receptors and cytolytic activity. J. Immunol.175, 5095–5103 (2005).
   PubMed Web of Science ®Google Scholar
• Galic Z, Kitchen SG, Kacena A et al. T lineage differentiation from human embryonic stem cells. Proc. Natl Acad. Sci. USA103, 11742–11747 (2006).
   PubMed Web of Science ®Google Scholar
• Lu SJ, Feng Q, Caballero S et al. Generation of functional hemangioblasts from human embryonic stem cells. Nat. Methods4, 501–509 (2007).
   PubMed Web of Science ®Google Scholar
• D’Souza SL, Elefanty AG, Keller G. SCL/Tal-1 is essential for hematopoietic commitment of the hemangioblast but not for its development. Blood105, 3862–3870 (2005).
   PubMedGoogle Scholar
• Choi KD, Yu J, Smuga-Otto K, Salvagiotto G et al. Hematopoietic and endothelial differentiation of human induced pluripotent stem cells. Stem Cells27(3), 559–567 (2009).
   PubMed Web of Science ®Google Scholar
• Okita K, Nakagawa M, Hyenjong H et al. Generation of mouse induced pluripotent stem cells without viral vectors. Science322, 949–953 (2008).
   PubMed Web of Science ®Google Scholar
• Stadtfeld M, Nagaya M, Utikal J et al. Induced pluripotent stem cells generated without viral integration. Science322, 945–949 (2008).
   PubMed Web of Science ®Google Scholar