Role of hydrogen sulfide in the female reproductive tract

References

• Reiffenstein RJ, Hulbert WC, Roth SH. Toxicology of hydrogen sulfide. Annu. Rev. Pharmacol. Toxicol.32, 109–134 (1992).
   PubMed Web of Science ®Google Scholar
• Abe K, Kimura H. The possible role of hydrogen sulfide as an endogenous neuromodulator. J. Neurosci.16(3), 1066–1071 (1996).
   PubMed Web of Science ®Google Scholar
• Hosoki R, Matsuki N, Kimura H. The possible role of hydrogen sulfide as an endogenous smooth muscle relaxant in synergy with nitric oxide. Biochem. Biophys. Res. Commun.237(3), 527–531 (1997).
   PubMed Web of Science ®Google Scholar
• Carson RJ, Seyffarth G, Mian R, Maddock H. Interactions between gasotransmitters. In: Signal Transduction and the Gasotransmitter. Wang R (Ed.). Humana Press, NJ, USA, 33–55 (2004).
   Google Scholar
• Acevedo CH, Ahmed A. Hemeoxygenase-1 inhibits human myometrial contractility via carbon monoxide and is upregulated by progesterone during pregnancy. J. Clin. Invest.101(5), 949–955 (1998).
   PubMed Web of Science ®Google Scholar
• Yallampalli C, Garfield RE, Byam-Smith M. Nitric oxide inhibits uterine contractility during pregnancy but not during delivery. Endocrinology133(4), 1899–1902 (1993).
   PubMed Web of Science ®Google Scholar
• Ledingham MA, Thomson AJ, Greer IA, Norman JE. Nitric oxide in parturition. BJOG107(5), 581–593 (2000).
   PubMedGoogle Scholar
• Wang R. Two’s company, three’s a crowd: can H2S be the third endogenous gaseous transmitter? FASEB J.16(13), 1792–1798 (2002).
   PubMed Web of Science ®Google Scholar
• Shibuya N, Tanaka M, Yoshida M et al. 3-mercaptopyruvate sulfurtransferase produces hydrogen sulfide and bound sulfane sulfur in the brain. Antioxid. Redox Signal.11(4), 703–714 (2009).
   PubMed Web of Science ®Google Scholar
• Shibuya N, Mikami Y, Kimura Y, Nagahara N, Kimura H. Vascular endothelium expresses 3-mercaptopyruvate sulfurtransferase and produces hydrogen sulfide. J. Biochem.146(5), 623–626 (2009).
   PubMed Web of Science ®Google Scholar
• Zhao W, Zhang J, Lu Y, Wang R. The vasorelaxant effect of H2S as a novel endogenous gaseous K(ATP) channel opener. EMBO J.20(21), 6008–6016 (2001).
   PubMed Web of Science ®Google Scholar
• Zhao W, Ndisang JF, Wang R. Modulation of endogenous production of H2S in rat tissues. Can. J. Physiol. Pharmacol.81(9), 848–853 (2003).
   PubMed Web of Science ®Google Scholar
• Stipanuk MH, Beck PW. Characterization of the enzymic capacity for cysteine desulphhydration in liver and kidney of the rat. Biochem. J.206(2), 267–277 (1982).
   PubMed Web of Science ®Google Scholar
• Bian JS, Yong QC, Pan TT et al. Role of hydrogen sulfide in the cardioprotection caused by ischemic preconditioning in the rat heart and cardiac myocytes. J. Pharmacol. Exp. Ther.316(2), 670–678 (2006).
   PubMed Web of Science ®Google Scholar
• Zerangue N, Kavanaugh MP. Interaction of L-cysteine with a human excitatory amino acid transporter. J. Physiol.493(Pt 2), 419–423 (1996).
   PubMed Web of Science ®Google Scholar
• Kimura H. Hydrogen sulfide: from brain to gut. Antioxid. Redox Signal. (2009) (Epub ahead of print).
   Google Scholar
• Lowicka E, Beltowski J. Hydrogen sulfide (H2S) – the third gas of interest for pharmacologists. Pharmacol. Rep.59(1), 4–24 (2007).
   PubMed Web of Science ®Google Scholar
• Whiteman M, Li L, Rose P, Tan CH, Parkinson D, Moore P. The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxid. Redox Signal. (2009) (Epub ahead of print).
   Google Scholar
• Olson KR. Is hydrogen sulfide a circulating ‘gasotransmitter’ in vertebrate blood? Biochim. Biophys. Acta1787(7), 856–863 (2009).
   PubMed Web of Science ®Google Scholar
• Ueland PM. Homocysteine species as components of plasma redox thiol status. Clin. Chem.41(3), 340–342 (1995).
   PubMed Web of Science ®Google Scholar
• Yaman H, Akgul EO, Kurt YG et al. Plasma total homocysteine concentrations in a Turkish population sample. Acta Cardiol.64(2), 247–251 (2009).
   PubMed Web of Science ®Google Scholar
• Tan IK, Gajra B. Plasma and urine amino acid profiles in a healthy adult population of Singapore. Ann. Acad. Med. Singap.35(7), 468–475 (2006).
   PubMed Web of Science ®Google Scholar
• Ishigami M, Hiraki K, Umemura K, Ogasawara Y, Ishii K, Kimura H. A source of hydrogen sulfide and a mechanism of its release in the brain. Antioxid. Redox Signal.11(2), 205–214 (2009).
   PubMed Web of Science ®Google Scholar
• Stipanuk MH. Sulfur amino acid metabolism: pathways for production and removal of homocysteine and cysteine. Annu. Rev. Nutr.24, 539–577 (2004).
   PubMed Web of Science ®Google Scholar
• Whiteman M, Moore PK. Hydrogen sulfide and the vasculature: a novel vasculoprotective entity and regulator of nitric oxide bioavailability? J. Cell. Mol. Med.13(3), 488–507 (2009).
   PubMed Web of Science ®Google Scholar
• Li L, Salto-Tellez M, Tan CH, Whiteman M, Moore PK. GYY4137, a novel hydrogen sulfide-releasing molecule, protects against endotoxic shock in the rat. Free Radic. Biol. Med.47(1), 103–113 (2009).
   PubMed Web of Science ®Google Scholar
• Pearson RJ, Wilson T, Wang R. Endogenous hydrogen sulfide and the cardiovascular system – what’s the smell all about? Clin. Invest. Med.29(3), 146–150 (2006).
   PubMed Web of Science ®Google Scholar
• Cheng Y, Ndisang JF, Tang G, Cao K, Wang R. Hydrogen sulfide-induced relaxation of resistance mesenteric artery beds of rats. Am. J. Physiol. Heart Circ. Physiol.287(5), H2316–H2323 (2004).
   PubMed Web of Science ®Google Scholar
• Kiss L, Deitch EA, Szabo C. Hydrogen sulfide decreases adenosine triphosphate levels in aortic rings and leads to vasorelaxation via metabolic inhibition. Life Sci.83(17–18), 589–594 (2008).
   PubMed Web of Science ®Google Scholar
• Lee SW, Cheng Y, Moore PK, Bian JS. Hydrogen sulphide regulates intracellular pH in vascular smooth muscle cells. Biochem. Biophys. Res. Commun.358(4), 1142–1147 (2007).
   PubMed Web of Science ®Google Scholar
• Zhao W, Wang R. H(2)S-induced vasorelaxation and underlying cellular and molecular mechanisms. Am. J. Physiol. Heart Circ. Physiol.283(2), H474–H480 (2002).
   PubMed Web of Science ®Google Scholar
• Yang G, Wu L, Jiang B et al. H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine γ-lyase. Science322(5901), 587–590 (2008).
   PubMed Web of Science ®Google Scholar
• Li L, Bhatia M, Moore PK. Hydrogen sulphide – a novel mediator of inflammation? Curr. Opin. Pharmacol.6(2), 125–129 (2006).
   PubMed Web of Science ®Google Scholar
• Hu LF, Wong PT, Moore PK, Bian JS. Hydrogen sulfide attenuates lipopolysaccharide-induced inflammation by inhibition of p38 mitogen-activated protein kinase in microglia. J. Neurochem.100(4), 1121–1128 (2007).
   PubMed Web of Science ®Google Scholar
• Kimura Y, Goto YI, Kimura H. Hydrogen sulfide increases glutathione production and suppresses oxidative stress in mitochondria. Antioxid. Redox Signal.12(1), 1–13 (2010).
   PubMed Web of Science ®Google Scholar
• Hayden LJ, Franklin KJ, Roth SH, Moore GJ. Inhibition of oxytocin-induced but not angiotensin-induced rat uterine contractions following exposure to sodium sulfide. Life Sci.45(26), 2557–2560 (1989).
   PubMed Web of Science ®Google Scholar
• Hayden LJ, Goeden H, Roth SH. Growth and development in the rat during sub-chronic exposure to low levels of hydrogen sulfide. Toxicol. Ind. Health6(3–4), 389–401 (1990).
   PubMed Web of Science ®Google Scholar
• Hayden LJ, Goeden H, Roth SH. Exposure to low levels of hydrogen sulfide elevates circulating glucose in maternal rats. J. Toxicol. Environ. Health31(1), 45–52 (1990).
   PubMed Web of Science ®Google Scholar
• Sidhu R, Singh M, Samir G, Carson RJ. L-cysteine and sodium hydrosulphide inhibit spontaneous contractility in isolated pregnant rat uterine strips in vitro. Pharmacol. Toxicol.88(4), 198–203 (2001).
   PubMedGoogle Scholar
• Wray S, Kupittayanant S, Shmygol A, Smith RD, Burdyga T. The physiological basis of uterine contractility: a short review. Exp. Physiol.86(2), 239–246 (2001).
   PubMed Web of Science ®Google Scholar
• Pierce SJ, Kupittayanant S, Shmygol T, Wray S. The effects of pH change on Ca2+ signaling and force in pregnant human myometrium. Am. J. Obstet. Gynecol.188(4), 1031–1038 (2003).
   PubMed Web of Science ®Google Scholar
• Patel P, Vatish M, Heptinstall J, Wang R, Carson RJ. The endogenous production of hydrogen sulphide in intrauterine tissues. Reprod. Biol. Endocrinol.7, 10 (2009).
   PubMedGoogle Scholar
• Chiku T, Padovani D, Zhu W, Singh S, Vitvitsky V, Banerjee R. H2S biogenesis by human cystathionine γ-lyase leads to the novel sulfur metabolites lanthionine and homolanthionine and is responsive to the grade of hyperhomocysteinemia. J. Biol. Chem.284(17), 11601–11612 (2009).
   PubMed Web of Science ®Google Scholar
• Aubard Y, Darodes N, Cantaloube M. Hyperhomocysteinemia and pregnancy – review of our present understanding and therapeutic implications. Eur. J. Obstet. Gynecol. Reprod. Biol.93(2), 157–165 (2000).
   PubMed Web of Science ®Google Scholar
• Steegers-Theunissen RP, Van Iersel CA, Peer PG, Nelen WL, Steegers EA. Hyperhomocysteinemia, pregnancy complications, and the timing of investigation. Obstet. Gynecol.104(2), 336–343 (2004).
   PubMed Web of Science ®Google Scholar
• Fayed MR, Youssef M, Odah MM. Hyperhomocysteinemia is a risk marker for development of maternal pre-eclampsia. Boll. Chim. Farm.143(7), 281–287 (2004).
   PubMedGoogle Scholar
• Seyffarth G, Nelson PN, Dunmore SJ, Rodrigo N, Murphy DJ, Carson RJ. Lipopolysaccharide induces nitric oxide synthase expression and platelet-activating factor increases nitric oxide production in human fetal membranes in culture. Reprod. Biol. Endocrinol.2, 29 (2004).
   PubMedGoogle Scholar
• Koenitzer JR, Isbell TS, Patel HD et al. Hydrogen sulfide mediates vasoactivity in an O2-dependent manner. Am. J. Physiol. Heart Circ. Physiol.292(4), H1953–H1960 (2007).
   PubMed Web of Science ®Google Scholar
• Srilatha B, Hu L, Adaikan GP, Moore PK. Initial characterization of hydrogen sulfide effects in female sexual function. J. Sex. Med.6(7), 1875–1884 (2009).
   PubMed Web of Science ®Google Scholar
• Guzman MA, Navarro MA, Carnicer R et al. Cystathionine β-synthase is essential for female reproductive function. Hum. Mol. Genet.15(21), 3168–3176 (2006).
   PubMed Web of Science ®Google Scholar
• VanAerts LA, Poirot CM, Herberts CA et al. Development of methionine synthase, cystathionine-β-synthase and S-adenosyl-homocysteine hydrolase during gestation in rats. J. Reprod. Fertil.103(2), 227–232 (1995).
   PubMedGoogle Scholar
• d’Emmanuele di Villa Bianca R, Sorrentino R, Maffia P et al. Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation. Proc. Natl Acad. Sci. USA106(11), 4513–4518 (2009).
   PubMed Web of Science ®Google Scholar
• Maul H, Longo M, Saade GR, Garfield RE. Nitric oxide and its role during pregnancy: from ovulation to delivery. Curr. Pharm. Des.9(5), 359–380 (2003).
   PubMed Web of Science ®Google Scholar
• Kubo S, Doe I, Kurokawa Y, Nishikawa H, Kawabata A. Direct inhibition of endothelial nitric oxide synthase by hydrogen sulfide: contribution to dual modulation of vascular tension. Toxicology232(1–2), 138–146 (2007).
   PubMed Web of Science ®Google Scholar
• Sweazea K, Walker BR. Antioxidant and vasodilatory effects of heme oxygenase on mesenteric vasoreactivity following chronic hypoxia. Microcirculation16(2), 131–141 (2009).
   PubMed Web of Science ®Google Scholar
• Olson KR, Dombkowski RA, Russell MJ et al. Hydrogen sulfide as an oxygen sensor/transducer in vertebrate hypoxic vasoconstriction and hypoxic vasodilation. J. Exp. Biol.209(Pt 20), 4011–4023 (2006).
   PubMed Web of Science ®Google Scholar
• Olson KR. Hydrogen sulfide and oxygen sensing in the cardiovascular system. Antioxid. Redox Signal. DOI: 10.1089/ars.2009.2921 (2009) (Epub ahead of print).
   Google Scholar
• Olson KR, Whitfield NL, Bearden SE et al. Hypoxic pulmonary vasodilation: a paradigm shift with a hydrogen sulfide mechanism. Am. J. Physiol. Regul. Integr. Comp. Physiol.298(1), R51–R60 (2010).
   PubMed Web of Science ®Google Scholar
• Srilatha B, Adaikan PG, Li L, Moore PK. Hydrogen sulphide: a novel endogenous gasotransmitter facilitates erectile function. J. Sex. Med.4(5), 1304–1311 (2007).
   PubMed Web of Science ®Google Scholar
• Vaisanen-Tommiska MR. Nitric oxide in the human uterine cervix: endogenous ripening factor. Ann. Med.40(1), 45–55 (2008).
   PubMed Web of Science ®Google Scholar
• Sidhapuriwala J, Li L, Sparatore A, Bhatia M, Moore PK. Effect of S-diclofenac, a novel hydrogen sulfide releasing derivative, on carrageenan-induced hindpaw oedema formation in the rat. Eur. J. Pharmacol.569(1–2), 149–154 (2007).
   PubMed Web of Science ®Google Scholar
• Baskar R, Sparatore A, Del Soldato P, Moore PK. Effect of S-diclofenac, a novel hydrogen sulfide releasing derivative inhibit rat vascular smooth muscle cell proliferation. Eur. J. Pharmacol.594(1–3), 1–8 (2008).
   PubMed Web of Science ®Google Scholar
• Nemmani KV, Mali SV, Borhade N et al. NO-NSAIDs: gastric-sparing nitric oxide-releasable prodrugs of non-steroidal anti-inflammatory drugs. Bioorg. Med. Chem. Lett.19(18), 5297–5301 (2009).
   PubMed Web of Science ®Google Scholar
• Li L, Whiteman M, Guan YY et al. Characterization of a novel, water-soluble hydrogen sulfide-releasing molecule (GYY4137): new insights into the biology of hydrogen sulfide. Circulation117(18), 2351–2360 (2008).
   PubMed Web of Science ®Google Scholar
• Shukla N, Rossoni G, Hotston M et al. Effect of hydrogen sulphide-donating sildenafil (ACS6) on erectile function and oxidative stress in rabbit isolated corpus cavernosum and in hypertensive rats. BJU Int.103(11), 1522–1529 (2009).
   PubMed Web of Science ®Google Scholar