Advanced search
Publication Cover
Expert Review of Obstetrics & Gynecology Volume 7, 2012 - Issue 3
Journal homepage
2,330
Views
1
CrossRef citations to date
0
Altmetric
Editorial

Boy or girl? The implications of using cell-free fetal DNA to decide fetal sex

Ji Hyae Lim Laboratory of Medical Genetics, Medical Research Institute, Cheil General Hospital and Women’s Healthcare Center, Seoul, Korea
,
So Yeon Park Laboratory of Medical Genetics, Medical Research Institute, Cheil General Hospital and Women’s Healthcare Center, Seoul, Korea
&
Hyun Mee Ryu Department of Obstetrics and Gynecology, Cheil General Hospital and Women’s Healthcare Center, KwanDong University College of Medicine, Seoul, Korea and Laboratory of Medical Genetics, Medical Research Institute, Cheil General Hospital and Women’s Healthcare Center, 1-19 Mookjung-dong, Jung-gu, Seoul 100-380, Korea. [email protected]
Pages 193-195 | Published online: 10 Jan 2014

References

  • Jahr S, Hentze H, Englisch S et al. DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells. Cancer Res.61, 1659–1665 (2001).
  • Lo YM, Corbetta N, Chamberlain PF et al. Presence of fetal DNA in maternal plasma and serum. Lancet350(9076), 485–487 (1997).
  • Tjoa ML, Cindrova-Davies T, Spasic-Boskovic O, Bianchi DW, Burton GJ. Trophoblastic oxidative stress and the release of cell-free feto-placental DNA. Am. J. Pathol.169, 400–404 (2006).
  • Lo YM, Tein MS, Lau TK et al. Quantitative analysis of fetal DNA in maternal plasma and serum: implications for noninvasive prenatal diagnosis. Am. J. Hum. Genet.62, 768–775 (1998).
  • Chan KC, Zhang J, Hui AB et al. Size distributions of maternal and fetal DNA in maternal plasma. Clin. Chem.50, 88–92 (2004).
  • Illanes S, Denbow M, Kailasam C, Finning K, Soothill PW. Early detection of cell-free fetal DNA in maternal plasma. Early Hum. Dev.83, 563–566 (2007).
  • Lo YM, Zhang J, Leung TN, Lau TK, Chang AM, Hjelm NM. Rapid clearance of fetal DNA from maternal plasma. Am. J. Hum. Genet.64, 218–224 (1999).
  • Hill M, Finning K, Martin P et al. Non-invasive prenatal determination of fetal sex. Clin. Genet.80(1), 68–75 (2011).
  • Chitty L, Mistry B, Hogg J et al. Prospective Register of Outcomes of Free-Fetal DNA Testing (PROOF) – results of the first year’s audit. J. Med. Genet.44(Suppl. 1), S28 (2007).
  • Devaney SA, Palomaki GE, Scott JA, Bianchi DW. Noninvasive fetal sex determination using cell-free fetal DNA: a systematic review and meta-analysis. JAMA306(6), 627–636 (2011).
  • Dhallan R, Au WC, Mattagajasingh S et al. Methods to increase the percentage of free fetal DNA recovered from the maternal circulation. JAMA291, 1114–1119 (2004).
  • Legler TJ, Liu Z, Mavrou A et al. Workshop report on the extraction of foetal DNA from maternal plasma. Prenat. Diagn.27, 824–829 (2007).
  • Scheffer PG, van der Schoot CE, Page-Christiaens GC, Bossers B, van Erp F, de Haas M. Reliability of fetal sex determination using maternal plasma. Obstet. Gynecol.115, 117–126 (2010).
  • Davanos N, Spathas DH. Relative quantitation of cell-free fetal DNA in maternal plasma using autosomal DNA markers. Clin. Chim. Acta412(17–18), 1539–1543 (2001).
  • Lim JH, Park SY, Kim SY et al. Effective detection of fetal sex using circulating fetal DNA in first-trimester maternal plasma. FASEB J.26(1), 250–258 (2012).
  • Odeh M, Granin V, Kais M, Ophir E, Bornstein J. Sonographic fetal sex determination. Obstet. Gynecol. Surv.64, 50–57 (2009).
  • Mujezinovic F, Alfirevic Z. Procedure-related complications of amniocentesis and chorionic villous sampling: a systematic review. Obstet. Gynecol.110, 687–694 (2007).
  • Avent ND, Chitty LS. Non-invasive diagnosis of fetal sex; utilisation of free fetal DNA in maternal plasma and ultrasound. Prenat. Diagn.26, 598–603 (2006).
  • Bianchi DW. At-home fetal DNA gender testing. Obstet. Gynecol.107(2 Pt 1), 216–218 (2006).
  • Javitt GH. Pink or blue? The need for regulation is black and white. Fertil. Steril.86(1), 13–15 (2006).
  • van den Heuvel A, Marteau TM. Cultural variation in values attached to informed choice in the context of prenatal diagnosis. Semin. Fetal Neonatal Med.13, 99–102 (2008).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.